Association between endocrine-disrupting chemical mixtures and non-alcoholic fatty liver disease with metabolic syndrome as a mediator among adults: A population-based study in Korea
Ecotoxicol Environ Saf. 2024 Apr 12;276:116310. doi: 10.1016/j.ecoenv.2024.116310. Online ahead of print.ABSTRACTEndocrine-disrupting chemicals (EDCs) may play a role in non-alcoholic fatty liver disease (NAFLD); however, studies on the combined effects of EDC mixtures on NAFLD development are limited. Here, we explored the association between exposure to EDC mixtures and NAFLD and investigated the potential mediating role of metabolic syndrome (MetS). We included participants from the Korean National Environmental Health Survey Cycle 4 (2018-2020) and quantified the urinary concentrations of various EDCs-eight phthalate m...
Source: Ecotoxicology and Environmental Safety - April 13, 2024 Category: Environmental Health Authors: Bohyun Park Byungmi Kim Chung Ho Kim Hyun Jin Oh Bomi Park Source Type: research
Biological markers of adipose tissue: Adipokines
Ann Endocrinol (Paris). 2024 Apr 16:S0003-4266(24)00050-7. doi: 10.1016/j.ando.2024.04.002. Online ahead of print.ABSTRACTWe currently have a large sum of clinical and experimental data documenting the involvement of numerous adipokines in the maintenance of energy homeostasis in healthy individuals and their dysregulation in diseases such as obesity, metabolic syndrome or type 2 diabetes. Despite the impressive discoveries made in this field over many years, much remains to be done before understanding all the physiological and pathological implications, and hoping for the development of other effective and safe therapeut...
Source: Annales d'Endocrinologie - April 13, 2024 Category: Endocrinology Authors: Jean-Philippe Bastard Imane Dridi-Brahimi Camille Vatier Soraya Fellahi Bruno F ève Source Type: research
Biological markers of adipose tissue: Adipokines
Ann Endocrinol (Paris). 2024 Apr 16:S0003-4266(24)00050-7. doi: 10.1016/j.ando.2024.04.002. Online ahead of print.ABSTRACTWe currently have a large sum of clinical and experimental data documenting the involvement of numerous adipokines in the maintenance of energy homeostasis in healthy individuals and their dysregulation in diseases such as obesity, metabolic syndrome or type 2 diabetes. Despite the impressive discoveries made in this field over many years, much remains to be done before understanding all the physiological and pathological implications, and hoping for the development of other effective and safe therapeut...
Source: Annales d'Endocrinologie - April 13, 2024 Category: Endocrinology Authors: Jean-Philippe Bastard Imane Dridi-Brahimi Camille Vatier Soraya Fellahi Bruno F ève Source Type: research
Biological Therapy for Psoriasis in Cancer Patients: An 8-Year Retrospective Real-Life Study
Conclusions: Our experience supports the effectiveness and safety of biological therapy for psoriasis in patients with a history of cancer or recent onset neoplasia.PMID:38610706 | DOI:10.3390/jcm13071940 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Teresa Battista Lucia Gallo Fabrizio Martora Davide Fattore Luca Potestio Sara Cacciapuoti Massimiliano Scalvenzi Matteo Megna Source Type: research
Biological Therapy for Psoriasis in Cancer Patients: An 8-Year Retrospective Real-Life Study
Conclusions: Our experience supports the effectiveness and safety of biological therapy for psoriasis in patients with a history of cancer or recent onset neoplasia.PMID:38610706 | DOI:10.3390/jcm13071940 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Teresa Battista Lucia Gallo Fabrizio Martora Davide Fattore Luca Potestio Sara Cacciapuoti Massimiliano Scalvenzi Matteo Megna Source Type: research
Biological markers of adipose tissue: Adipokines
Ann Endocrinol (Paris). 2024 Apr 16:S0003-4266(24)00050-7. doi: 10.1016/j.ando.2024.04.002. Online ahead of print.ABSTRACTWe currently have a large sum of clinical and experimental data documenting the involvement of numerous adipokines in the maintenance of energy homeostasis in healthy individuals and their dysregulation in diseases such as obesity, metabolic syndrome or type 2 diabetes. Despite the impressive discoveries made in this field over many years, much remains to be done before understanding all the physiological and pathological implications, and hoping for the development of other effective and safe therapeut...
Source: Annales d'Endocrinologie - April 13, 2024 Category: Endocrinology Authors: Jean-Philippe Bastard Imane Dridi-Brahimi Camille Vatier Soraya Fellahi Bruno F ève Source Type: research
Association between endocrine-disrupting chemical mixtures and non-alcoholic fatty liver disease with metabolic syndrome as a mediator among adults: A population-based study in Korea
Ecotoxicol Environ Saf. 2024 Apr 12;276:116310. doi: 10.1016/j.ecoenv.2024.116310. Online ahead of print.ABSTRACTEndocrine-disrupting chemicals (EDCs) may play a role in non-alcoholic fatty liver disease (NAFLD); however, studies on the combined effects of EDC mixtures on NAFLD development are limited. Here, we explored the association between exposure to EDC mixtures and NAFLD and investigated the potential mediating role of metabolic syndrome (MetS). We included participants from the Korean National Environmental Health Survey Cycle 4 (2018-2020) and quantified the urinary concentrations of various EDCs-eight phthalate m...
Source: Ecotoxicology and Environmental Safety - April 13, 2024 Category: Environmental Health Authors: Bohyun Park Byungmi Kim Chung Ho Kim Hyun Jin Oh Bomi Park Source Type: research
Biological Therapy for Psoriasis in Cancer Patients: An 8-Year Retrospective Real-Life Study
Conclusions: Our experience supports the effectiveness and safety of biological therapy for psoriasis in patients with a history of cancer or recent onset neoplasia.PMID:38610706 | PMC:PMC11012886 | DOI:10.3390/jcm13071940 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Teresa Battista Lucia Gallo Fabrizio Martora Davide Fattore Luca Potestio Sara Cacciapuoti Massimiliano Scalvenzi Matteo Megna Source Type: research
The Cancer-Protective Potential of Protocatechuic Acid: A Narrative Review
Molecules. 2024 Mar 23;29(7):1439. doi: 10.3390/molecules29071439.ABSTRACTCancer is one of the leading causes of death worldwide, making the search for alternatives for its control a critical issue. In this context, exploring alternatives from natural sources, such as certain vegetables containing a variety of secondary metabolites with beneficial effects on the body and that play a crucial role in the fight against cancer, is essential. Among the compounds with the greatest efficacy in controlling this disease, those with antioxidant activity, particularly phenolic com-pounds, stand out. A remarkable example of this group...
Source: Cancer Control - April 13, 2024 Category: Cancer & Oncology Authors: Jorge Cadena-I ñiguez Edelmiro Santiago-Osorio Nancy S ánchez-Flores Sandra Salazar-Aguilar Ram ón Marcos Soto-Hernández Mar ía de la Luz Riviello-Flores V íctor Manuel Macías-Zaragoza Itzen Agui ñiga-Sánchez Source Type: research
Biological Therapy for Psoriasis in Cancer Patients: An 8-Year Retrospective Real-Life Study
Conclusions: Our experience supports the effectiveness and safety of biological therapy for psoriasis in patients with a history of cancer or recent onset neoplasia.PMID:38610706 | DOI:10.3390/jcm13071940 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Teresa Battista Lucia Gallo Fabrizio Martora Davide Fattore Luca Potestio Sara Cacciapuoti Massimiliano Scalvenzi Matteo Megna Source Type: research
Fractional Excretion of Urate is Positively Associated with Type 2 Diabetes in HUA Patients: A Cross-Sectional Study
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 13, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Metabolic effects of testosterone added to intensive lifestyle intervention in older men with obesity and hypogonadism
CONCLUSION: In older men with obesity and hypogonadism, adding TRT for six months to LT does not result in further improved cardiometabolic profiles, and could potentially blunt some of the metabolic benefits induced by LT.PMID:38606934 | DOI:10.1210/clinem/dgae249 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Adrian M Gonzalez-Gil Yoann Barnouin Alessandra Celli Viola Viola Marcos D Villarreal Maria Liza Duremdes Nava Adam Sciuk Clifford Qualls Reina Armamento-Villareal Dennis T Villareal Source Type: research
Regulation of host metabolic health by parasitic helminths
Trends Parasitol. 2024 Apr 11:S1471-4922(24)00073-4. doi: 10.1016/j.pt.2024.03.006. Online ahead of print.ABSTRACTObesity is a worldwide pandemic and major risk factor for the development of metabolic syndrome (MetS) and type 2 diabetes (T2D). T2D requires lifelong medical support to limit complications and is defined by impaired glucose tolerance, insulin resistance (IR), and chronic low-level systemic inflammation initiating from adipose tissue. The current preventative strategies include a healthy diet, controlled physical activity, and medication targeting hyperglycemia, with underexplored underlying inflammation. Stud...
Source: Trends in Parasitology - April 12, 2024 Category: Parasitology Authors: Suchandan Sikder Doris Pierce Eti R Sarkar Connor McHugh Kate G R Quinlan Paul Giacomin Alex Loukas Source Type: research
Regulation of host metabolic health by parasitic helminths
Trends Parasitol. 2024 Apr 11:S1471-4922(24)00073-4. doi: 10.1016/j.pt.2024.03.006. Online ahead of print.ABSTRACTObesity is a worldwide pandemic and major risk factor for the development of metabolic syndrome (MetS) and type 2 diabetes (T2D). T2D requires lifelong medical support to limit complications and is defined by impaired glucose tolerance, insulin resistance (IR), and chronic low-level systemic inflammation initiating from adipose tissue. The current preventative strategies include a healthy diet, controlled physical activity, and medication targeting hyperglycemia, with underexplored underlying inflammation. Stud...
Source: Trends in Parasitology - April 12, 2024 Category: Parasitology Authors: Suchandan Sikder Doris Pierce Eti R Sarkar Connor McHugh Kate G R Quinlan Paul Giacomin Alex Loukas Source Type: research
Impact of diabetes mellitus on osteoarthritis: a scoping review on biomarkers
Expert Rev Mol Med. 2024 Apr 12;26:e8. doi: 10.1017/erm.2024.7.ABSTRACTOsteoarthritis (OA) commonly affects the knee and hip joints and accounts for 19.3% of disability-adjusted life years and years lived with disability worldwide (Refs , ). Early management is important in order to avoid disability uphold quality of life (Ref. ). However, a lack of awareness of subclinical and early symptomatic stages of OA often hampers early management (Ref. ). Moreover, late diagnosis of OA among those with severe disease, at a stage when OA management becomes more complicated is common (Refs , , , ). Established risk factors for the d...
Source: Molecular Medicine - April 12, 2024 Category: Molecular Biology Authors: Shi Rui Seow Sumaiyah Mat Amalina Ahmad Azam Nor Fadilah Rajab Intan Safinar Ismail Devinder Kaur Ajit Singh Suzana Shahar Maw Pin Tan Francis Berenbaum Source Type: research
