Apicomplexa micropore: history, function, and formation
Trends Parasitol. 2024 Apr 17:S1471-4922(24)00079-5. doi: 10.1016/j.pt.2024.03.008. Online ahead of print.ABSTRACTThe micropore, a mysterious structure found in apicomplexan species, was recently shown to be essential for nutrient acquisition in Plasmodium falciparum and Toxoplasma gondii. However, the differences between the micropores of these two parasites questions the nature of a general apicomplexan micropore structure and whether the formation process model from Plasmodium can be applied to other apicomplexans. We analyzed the literature on different apicomplexan micropores and found that T. gondii probably harbors ...
Source: Trends in Parasitology - April 18, 2024 Category: Parasitology Authors: Jiong Yang Shaojun Long Geoff Hide Zhao-Rong Lun De-Hua Lai Source Type: research
Apicomplexa micropore: history, function, and formation
Trends Parasitol. 2024 Apr 17:S1471-4922(24)00079-5. doi: 10.1016/j.pt.2024.03.008. Online ahead of print.ABSTRACTThe micropore, a mysterious structure found in apicomplexan species, was recently shown to be essential for nutrient acquisition in Plasmodium falciparum and Toxoplasma gondii. However, the differences between the micropores of these two parasites questions the nature of a general apicomplexan micropore structure and whether the formation process model from Plasmodium can be applied to other apicomplexans. We analyzed the literature on different apicomplexan micropores and found that T. gondii probably harbors ...
Source: Trends in Parasitology - April 18, 2024 Category: Parasitology Authors: Jiong Yang Shaojun Long Geoff Hide Zhao-Rong Lun De-Hua Lai Source Type: research
Apicomplexa micropore: history, function, and formation
Trends Parasitol. 2024 Apr 17:S1471-4922(24)00079-5. doi: 10.1016/j.pt.2024.03.008. Online ahead of print.ABSTRACTThe micropore, a mysterious structure found in apicomplexan species, was recently shown to be essential for nutrient acquisition in Plasmodium falciparum and Toxoplasma gondii. However, the differences between the micropores of these two parasites questions the nature of a general apicomplexan micropore structure and whether the formation process model from Plasmodium can be applied to other apicomplexans. We analyzed the literature on different apicomplexan micropores and found that T. gondii probably harbors ...
Source: Trends in Parasitology - April 18, 2024 Category: Parasitology Authors: Jiong Yang Shaojun Long Geoff Hide Zhao-Rong Lun De-Hua Lai Source Type: research
Cystoisospora suis
Trends Parasitol. 2024 Apr 12:S1471-4922(24)00082-5. doi: 10.1016/j.pt.2024.03.009. Online ahead of print.NO ABSTRACTPMID:38614866 | DOI:10.1016/j.pt.2024.03.009 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 13, 2024 Category: Parasitology Authors: Anna Sophia Feix Anja Joachim Source Type: research
Cystoisospora suis
Trends Parasitol. 2024 Apr 12:S1471-4922(24)00082-5. doi: 10.1016/j.pt.2024.03.009. Online ahead of print.NO ABSTRACTPMID:38614866 | DOI:10.1016/j.pt.2024.03.009 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 13, 2024 Category: Parasitology Authors: Anna Sophia Feix Anja Joachim Source Type: research
Cystoisospora suis
Trends Parasitol. 2024 Apr 12:S1471-4922(24)00082-5. doi: 10.1016/j.pt.2024.03.009. Online ahead of print.NO ABSTRACTPMID:38614866 | DOI:10.1016/j.pt.2024.03.009 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 13, 2024 Category: Parasitology Authors: Anna Sophia Feix Anja Joachim Source Type: research
MAM 2024: Malaria in a changing world
Trends Parasitol. 2024 Apr 11:S1471-4922(24)00074-6. doi: 10.1016/j.pt.2024.03.007. Online ahead of print.NO ABSTRACTPMID:38609740 | DOI:10.1016/j.pt.2024.03.007 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 12, 2024 Category: Parasitology Authors: Rhea J Longley Josephine Malinga Eva Hesping Edwin Sutanto Sophia M DonVito Michal Kucharski Damian A Oyong Julie M J Verhoef Esrah Du Elizabeth Villasis Kioko Mwikali Source Type: research
Regulation of host metabolic health by parasitic helminths
Trends Parasitol. 2024 Apr 11:S1471-4922(24)00073-4. doi: 10.1016/j.pt.2024.03.006. Online ahead of print.ABSTRACTObesity is a worldwide pandemic and major risk factor for the development of metabolic syndrome (MetS) and type 2 diabetes (T2D). T2D requires lifelong medical support to limit complications and is defined by impaired glucose tolerance, insulin resistance (IR), and chronic low-level systemic inflammation initiating from adipose tissue. The current preventative strategies include a healthy diet, controlled physical activity, and medication targeting hyperglycemia, with underexplored underlying inflammation. Stud...
Source: Trends in Parasitology - April 12, 2024 Category: Parasitology Authors: Suchandan Sikder Doris Pierce Eti R Sarkar Connor McHugh Kate G R Quinlan Paul Giacomin Alex Loukas Source Type: research
MAM 2024: Malaria in a changing world
Trends Parasitol. 2024 Apr 11:S1471-4922(24)00074-6. doi: 10.1016/j.pt.2024.03.007. Online ahead of print.NO ABSTRACTPMID:38609740 | DOI:10.1016/j.pt.2024.03.007 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 12, 2024 Category: Parasitology Authors: Rhea J Longley Josephine Malinga Eva Hesping Edwin Sutanto Sophia M DonVito Michal Kucharski Damian A Oyong Julie M J Verhoef Esrah Du Elizabeth Villasis Kioko Mwikali Source Type: research
Regulation of host metabolic health by parasitic helminths
Trends Parasitol. 2024 Apr 11:S1471-4922(24)00073-4. doi: 10.1016/j.pt.2024.03.006. Online ahead of print.ABSTRACTObesity is a worldwide pandemic and major risk factor for the development of metabolic syndrome (MetS) and type 2 diabetes (T2D). T2D requires lifelong medical support to limit complications and is defined by impaired glucose tolerance, insulin resistance (IR), and chronic low-level systemic inflammation initiating from adipose tissue. The current preventative strategies include a healthy diet, controlled physical activity, and medication targeting hyperglycemia, with underexplored underlying inflammation. Stud...
Source: Trends in Parasitology - April 12, 2024 Category: Parasitology Authors: Suchandan Sikder Doris Pierce Eti R Sarkar Connor McHugh Kate G R Quinlan Paul Giacomin Alex Loukas Source Type: research
A targetable receptor-binding site on PfCyRPA to aid in the fight against malaria
Trends Parasitol. 2024 Apr 10:S1471-4922(24)00083-7. doi: 10.1016/j.pt.2024.04.001. Online ahead of print.ABSTRACTRecently, Day et al. identified a receptor-binding site on the malaria parasite protein PfCyRPA that binds the host sugar Neu5Ac, and they found that disrupting this interaction impedes parasite growth. A map of the receptor-binding site identifies an attractive target for antimalarial vaccines and therapeutics.PMID:38604871 | DOI:10.1016/j.pt.2024.04.001 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 11, 2024 Category: Parasitology Authors: Thayne H Dickey Niraj H Tolia Source Type: research
A paradigm for Africa-centric vaccine development in Equatorial Guinea
Trends Parasitol. 2024 Apr 5:S1471-4922(24)00072-2. doi: 10.1016/j.pt.2024.03.005. Online ahead of print.ABSTRACTThe Equatorial Guinea Malaria Vaccine Initiative (EGMVI) highlights how long-term African government and international energy industry investment, plus novel partnerships, can enable clinical development of vaccines in Africa, for Africa. We review achievements and challenges of this pioneering, award-winning, public-private partnership which offers a model for future Africa-centric clinical research and development (R&D).PMID:38582683 | DOI:10.1016/j.pt.2024.03.005 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 6, 2024 Category: Parasitology Authors: Peter F Billingsley Thomas L Richie Salim Abdulla Mitoha Ondo'o Ayekaba Claudia A Daubenberger Gu íllermo A Garcia Stephen L Hoffman Source Type: research
A paradigm for Africa-centric vaccine development in Equatorial Guinea
Trends Parasitol. 2024 Apr 5:S1471-4922(24)00072-2. doi: 10.1016/j.pt.2024.03.005. Online ahead of print.ABSTRACTThe Equatorial Guinea Malaria Vaccine Initiative (EGMVI) highlights how long-term African government and international energy industry investment, plus novel partnerships, can enable clinical development of vaccines in Africa, for Africa. We review achievements and challenges of this pioneering, award-winning, public-private partnership which offers a model for future Africa-centric clinical research and development (R&D).PMID:38582683 | DOI:10.1016/j.pt.2024.03.005 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 6, 2024 Category: Parasitology Authors: Peter F Billingsley Thomas L Richie Salim Abdulla Mitoha Ondo'o Ayekaba Claudia A Daubenberger Gu íllermo A Garcia Stephen L Hoffman Source Type: research
A paradigm for Africa-centric vaccine development in Equatorial Guinea
Trends Parasitol. 2024 Apr 5:S1471-4922(24)00072-2. doi: 10.1016/j.pt.2024.03.005. Online ahead of print.ABSTRACTThe Equatorial Guinea Malaria Vaccine Initiative (EGMVI) highlights how long-term African government and international energy industry investment, plus novel partnerships, can enable clinical development of vaccines in Africa, for Africa. We review achievements and challenges of this pioneering, award-winning, public-private partnership which offers a model for future Africa-centric clinical research and development (R&D).PMID:38582683 | DOI:10.1016/j.pt.2024.03.005 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 6, 2024 Category: Parasitology Authors: Peter F Billingsley Thomas L Richie Salim Abdulla Mitoha Ondo'o Ayekaba Claudia A Daubenberger Gu íllermo A Garcia Stephen L Hoffman Source Type: research
A paradigm for Africa-centric vaccine development in Equatorial Guinea
Trends Parasitol. 2024 Apr 5:S1471-4922(24)00072-2. doi: 10.1016/j.pt.2024.03.005. Online ahead of print.ABSTRACTThe Equatorial Guinea Malaria Vaccine Initiative (EGMVI) highlights how long-term African government and international energy industry investment, plus novel partnerships, can enable clinical development of vaccines in Africa, for Africa. We review achievements and challenges of this pioneering, award-winning, public-private partnership which offers a model for future Africa-centric clinical research and development (R&D).PMID:38582683 | DOI:10.1016/j.pt.2024.03.005 (Source: Trends in Parasitology)
Source: Trends in Parasitology - April 6, 2024 Category: Parasitology Authors: Peter F Billingsley Thomas L Richie Salim Abdulla Mitoha Ondo'o Ayekaba Claudia A Daubenberger Gu íllermo A Garcia Stephen L Hoffman Source Type: research
