The two parasite species formerly known as Plasmodium ovale
Trends Parasitol. 2023 Nov 30:S1471-4922(23)00284-2. doi: 10.1016/j.pt.2023.11.004. Online ahead of print.ABSTRACTPlasmodium ovale was the last of the exclusively human malaria parasites to be described, in 1922, and has remained the least well studied. Beginning in 1995, two divergent forms of the parasite, later termed 'classic' and 'variant', were described. By 2010, it was realised that these forms are two closely related, but genetically distinct and non-recombining species; they were given the names Plasmodium ovale curtisi and Plasmodium ovale wallikeri. Since then, substantial additional data have confirmed that th...
Source: Trends in Parasitology - December 1, 2023 Category: Parasitology Authors: Georges Snounou Paul M Sharp Richard Culleton Source Type: research
Current and upcoming point-of-care diagnostics for schistosomiasis
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00280-5. doi: 10.1016/j.pt.2023.10.005. Online ahead of print.ABSTRACTPoint-of-care (POC) diagnostics are simple and effective portable tools that can be used for fast mapping of helminthic diseases and monitoring control programs. Most POC tests (POCTs) available for schistosomiasis diagnosis are lateral flow immunoassays (LFIAs). The emergence of simple and rapid DNA isolation methods, along with isothermal nucleic acid amplification strategies - for example, loop-mediated isothermal amplification (LAMP) and recombinase polymerase amplification (RPA) - and recent clustered regu...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Jonas Rivera Yi Mu Catherine A Gordon Malcolm K Jones Guofeng Cheng Pengfei Cai Source Type: research
Advances and challenges in synthetic biology for mosquito control
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00281-7. doi: 10.1016/j.pt.2023.11.001. Online ahead of print.ABSTRACTMosquito-borne illnesses represent a significant global health peril, resulting in approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are continuously expanding their global reach, driven by factors that escalate mosquito populations and pathogen transmission. Innovative control measures are imperative to combat these catastrophic ailments. Conventional approaches, such as eliminating breeding sites and using insecticides, have been helpful, but they face challenges such as inse...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Shih-Che Weng Reem A Masri Omar S Akbari Source Type: research
Current and upcoming point-of-care diagnostics for schistosomiasis
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00280-5. doi: 10.1016/j.pt.2023.10.005. Online ahead of print.ABSTRACTPoint-of-care (POC) diagnostics are simple and effective portable tools that can be used for fast mapping of helminthic diseases and monitoring control programs. Most POC tests (POCTs) available for schistosomiasis diagnosis are lateral flow immunoassays (LFIAs). The emergence of simple and rapid DNA isolation methods, along with isothermal nucleic acid amplification strategies - for example, loop-mediated isothermal amplification (LAMP) and recombinase polymerase amplification (RPA) - and recent clustered regu...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Jonas Rivera Yi Mu Catherine A Gordon Malcolm K Jones Guofeng Cheng Pengfei Cai Source Type: research
Advances and challenges in synthetic biology for mosquito control
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00281-7. doi: 10.1016/j.pt.2023.11.001. Online ahead of print.ABSTRACTMosquito-borne illnesses represent a significant global health peril, resulting in approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are continuously expanding their global reach, driven by factors that escalate mosquito populations and pathogen transmission. Innovative control measures are imperative to combat these catastrophic ailments. Conventional approaches, such as eliminating breeding sites and using insecticides, have been helpful, but they face challenges such as inse...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Shih-Che Weng Reem A Masri Omar S Akbari Source Type: research
Current and upcoming point-of-care diagnostics for schistosomiasis
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00280-5. doi: 10.1016/j.pt.2023.10.005. Online ahead of print.ABSTRACTPoint-of-care (POC) diagnostics are simple and effective portable tools that can be used for fast mapping of helminthic diseases and monitoring control programs. Most POC tests (POCTs) available for schistosomiasis diagnosis are lateral flow immunoassays (LFIAs). The emergence of simple and rapid DNA isolation methods, along with isothermal nucleic acid amplification strategies - for example, loop-mediated isothermal amplification (LAMP) and recombinase polymerase amplification (RPA) - and recent clustered regu...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Jonas Rivera Yi Mu Catherine A Gordon Malcolm K Jones Guofeng Cheng Pengfei Cai Source Type: research
Advances and challenges in synthetic biology for mosquito control
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00281-7. doi: 10.1016/j.pt.2023.11.001. Online ahead of print.ABSTRACTMosquito-borne illnesses represent a significant global health peril, resulting in approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are continuously expanding their global reach, driven by factors that escalate mosquito populations and pathogen transmission. Innovative control measures are imperative to combat these catastrophic ailments. Conventional approaches, such as eliminating breeding sites and using insecticides, have been helpful, but they face challenges such as inse...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Shih-Che Weng Reem A Masri Omar S Akbari Source Type: research
Current and upcoming point-of-care diagnostics for schistosomiasis
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00280-5. doi: 10.1016/j.pt.2023.10.005. Online ahead of print.ABSTRACTPoint-of-care (POC) diagnostics are simple and effective portable tools that can be used for fast mapping of helminthic diseases and monitoring control programs. Most POC tests (POCTs) available for schistosomiasis diagnosis are lateral flow immunoassays (LFIAs). The emergence of simple and rapid DNA isolation methods, along with isothermal nucleic acid amplification strategies - for example, loop-mediated isothermal amplification (LAMP) and recombinase polymerase amplification (RPA) - and recent clustered regu...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Jonas Rivera Yi Mu Catherine A Gordon Malcolm K Jones Guofeng Cheng Pengfei Cai Source Type: research
Advances and challenges in synthetic biology for mosquito control
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00281-7. doi: 10.1016/j.pt.2023.11.001. Online ahead of print.ABSTRACTMosquito-borne illnesses represent a significant global health peril, resulting in approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are continuously expanding their global reach, driven by factors that escalate mosquito populations and pathogen transmission. Innovative control measures are imperative to combat these catastrophic ailments. Conventional approaches, such as eliminating breeding sites and using insecticides, have been helpful, but they face challenges such as inse...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Shih-Che Weng Reem A Masri Omar S Akbari Source Type: research
Current and upcoming point-of-care diagnostics for schistosomiasis
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00280-5. doi: 10.1016/j.pt.2023.10.005. Online ahead of print.ABSTRACTPoint-of-care (POC) diagnostics are simple and effective portable tools that can be used for fast mapping of helminthic diseases and monitoring control programs. Most POC tests (POCTs) available for schistosomiasis diagnosis are lateral flow immunoassays (LFIAs). The emergence of simple and rapid DNA isolation methods, along with isothermal nucleic acid amplification strategies - for example, loop-mediated isothermal amplification (LAMP) and recombinase polymerase amplification (RPA) - and recent clustered regu...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Jonas Rivera Yi Mu Catherine A Gordon Malcolm K Jones Guofeng Cheng Pengfei Cai Source Type: research
Advances and challenges in synthetic biology for mosquito control
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00281-7. doi: 10.1016/j.pt.2023.11.001. Online ahead of print.ABSTRACTMosquito-borne illnesses represent a significant global health peril, resulting in approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are continuously expanding their global reach, driven by factors that escalate mosquito populations and pathogen transmission. Innovative control measures are imperative to combat these catastrophic ailments. Conventional approaches, such as eliminating breeding sites and using insecticides, have been helpful, but they face challenges such as inse...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Shih-Che Weng Reem A Masri Omar S Akbari Source Type: research
Advances and challenges in synthetic biology for mosquito control
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00281-7. doi: 10.1016/j.pt.2023.11.001. Online ahead of print.ABSTRACTMosquito-borne illnesses represent a significant global health peril, resulting in approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are continuously expanding their global reach, driven by factors that escalate mosquito populations and pathogen transmission. Innovative control measures are imperative to combat these catastrophic ailments. Conventional approaches, such as eliminating breeding sites and using insecticides, have been helpful, but they face challenges such as inse...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Shih-Che Weng Reem A Masri Omar S Akbari Source Type: research
Current and upcoming point-of-care diagnostics for schistosomiasis
Trends Parasitol. 2023 Nov 23:S1471-4922(23)00280-5. doi: 10.1016/j.pt.2023.10.005. Online ahead of print.ABSTRACTPoint-of-care (POC) diagnostics are simple and effective portable tools that can be used for fast mapping of helminthic diseases and monitoring control programs. Most POC tests (POCTs) available for schistosomiasis diagnosis are lateral flow immunoassays (LFIAs). The emergence of simple and rapid DNA isolation methods, along with isothermal nucleic acid amplification strategies - for example, loop-mediated isothermal amplification (LAMP) and recombinase polymerase amplification (RPA) - and recent clustered regu...
Source: Trends in Parasitology - November 24, 2023 Category: Parasitology Authors: Jonas Rivera Yi Mu Catherine A Gordon Malcolm K Jones Guofeng Cheng Pengfei Cai Source Type: research
Copper in parasitic protists - a hitherto neglected virulence factor
Trends Parasitol. 2023 Nov 21:S1471-4922(23)00278-7. doi: 10.1016/j.pt.2023.10.003. Online ahead of print.ABSTRACTCopper plays a fundamental role in aerobic metabolism, but its role is double-edged, given its toxicity. Our understanding of copper metabolism in parasites remains rudimentary, despite its significance in virulence. Here we discuss how parasitic protists control copper homeostasis and show the potential key players identified by our bioinformatic analysis.PMID:37993308 | DOI:10.1016/j.pt.2023.10.003 (Source: Trends in Parasitology)
Source: Trends in Parasitology - November 22, 2023 Category: Parasitology Authors: Maria Grechnikova Zolt án Füssy Robert Sutak Source Type: research
Copper in parasitic protists - a hitherto neglected virulence factor
Trends Parasitol. 2023 Nov 21:S1471-4922(23)00278-7. doi: 10.1016/j.pt.2023.10.003. Online ahead of print.ABSTRACTCopper plays a fundamental role in aerobic metabolism, but its role is double-edged, given its toxicity. Our understanding of copper metabolism in parasites remains rudimentary, despite its significance in virulence. Here we discuss how parasitic protists control copper homeostasis and show the potential key players identified by our bioinformatic analysis.PMID:37993308 | DOI:10.1016/j.pt.2023.10.003 (Source: Trends in Parasitology)
Source: Trends in Parasitology - November 22, 2023 Category: Parasitology Authors: Maria Grechnikova Zolt án Füssy Robert Sutak Source Type: research
