A targetable receptor-binding site on PfCyRPA to aid in the fight against malaria

Trends Parasitol. 2024 Apr 10:S1471-4922(24)00083-7. doi: 10.1016/j.pt.2024.04.001. Online ahead of print.ABSTRACTRecently, Day et al. identified a receptor-binding site on the malaria parasite protein PfCyRPA that binds the host sugar Neu5Ac, and they found that disrupting this interaction impedes parasite growth. A map of the receptor-binding site identifies an attractive target for antimalarial vaccines and therapeutics.PMID:38604871 | DOI:10.1016/j.pt.2024.04.001
Source: Trends in Parasitology - Category: Parasitology Authors: Source Type: research