Gene expression signatures predict response to therapy with growth hormone
The Pharmacogenomics Journal, Published online: 27 May 2021; doi:10.1038/s41397-021-00237-5Gene expression signatures predict response to therapy with growth hormone (Source: The Pharmacogenomics Journal)
Source: The Pharmacogenomics Journal - May 27, 2021 Category: Drugs & Pharmacology Authors: Adam Stevens Philip Murray Chiara De Leonibus Terence Garner Ekaterina Koledova Geoffrey Ambler Klaus Kapelari Gerhard Binder Mohamad Maghnie Stefano Zucchini Elena Bashnina Julia Skorodok Diego Yeste Alicia Belgorosky Juan-Pedro Lopez Siguero Regis Couta Source Type: research
Identification and mapping of CpPM10.1, a major gene involved in powdery mildew (race 2 France of Podosphaera xanthii) resistance in zucchini (Cucurbita pepo L.)
This study not only provides highly stable PM resistance gene resources for cucurbit crops but also lays the foundation for the functional analysis of PM resistance and resistance breeding in zucchini.PMID:33914112 | DOI:10.1007/s00122-021-03840-z (Source: TAG. Theoretical and Applied Genetics)
Source: TAG. Theoretical and Applied Genetics - April 29, 2021 Category: Genetics & Stem Cells Authors: Yunli Wang Cong Qi Yusong Luo Feng Zhang Zuyun Dai Man Li Shuping Qu Source Type: research
Analysis of the molecular and biological variability of Zucchini yellow mosaic virus isolates from Iran and Iraq
Gene. 2021 Apr 19:145674. doi: 10.1016/j.gene.2021.145674. Online ahead of print.ABSTRACTDuring the growing season of 2018, several field-grown cucurbit plants in different parts of Iraq and Iran were surveyed for the presence of zucchini yellow mosaic virus (ZYMV), using two degenerate primer pairs (CIF/Rev and NIb2F/3R) targeting the two separated partial regions of the potyvirus genome (CI and NIb respectively). 7 out of 20 samples were confirmed to be infected with ZYMV. Phylogenetic analyses based on the CI gene grouped all Iranian and two Iraqi (ZYMV1 and ZYMV2) isolates together with isolates from the Middle East in...
Source: Gene - April 22, 2021 Category: Genetics & Stem Cells Authors: Hayder R Alinizi Mohsen Mehrvar Mohammad Zakiaghl Source Type: research
Analysis of the molecular and biological variability of Zucchini yellow mosaic virus isolates from Iran and Iraq
Gene. 2021 Apr 19:145674. doi: 10.1016/j.gene.2021.145674. Online ahead of print.ABSTRACTDuring the growing season of 2018, several field-grown cucurbit plants in different parts of Iraq and Iran were surveyed for the presence of zucchini yellow mosaic virus (ZYMV), using two degenerate primer pairs (CIF/Rev and NIb2F/3R) targeting the two separated partial regions of the potyvirus genome (CI and NIb respectively). 7 out of 20 samples were confirmed to be infected with ZYMV. Phylogenetic analyses based on the CI gene grouped all Iranian and two Iraqi (ZYMV1 and ZYMV2) isolates together with isolates from the Middle East in...
Source: Gene - April 22, 2021 Category: Genetics & Stem Cells Authors: Hayder R Alinizi Mohsen Mehrvar Mohammad Zakiaghl Source Type: research
Porous tantalum acetabular cups for reconstructions after peri-acetabular resections of primary bone tumours
CONCLUSIONS: The used PT AC had good medium-term survival rates and good functional results. This technique is a viable reconstructive option after resections of periacetabular primary bone sarcomas.PMID:33829914 | DOI:10.1177/11207000211001552 (Source: Hip International)
Source: Hip International - April 8, 2021 Category: Orthopaedics Authors: Riccardo Zucchini Andrea Sambri Claudio Giannini Michele Fiore Carlotta Calamelli Davide Maria Donati Massimiliano De Paolis Source Type: research
Post-operative outcomes of different surgical approaches to oropharyngeal squamous cell cancer: a case-matched study
CONCLUSION: In comparison with transmandibular surgery, transoral laser microsurgery and lateral pharyngotomy were associated with fewer complications and faster functional recovery. Lateral pharyngotomy had a higher rate of positive margins than transoral laser microsurgery, with a consequently greater need for adjuvant therapy. Many patients are nonetheless unsuitable for transoral surgery. All these factors should be considered when deciding on oropharyngeal cancer surgical treatment.PMID:33818328 | DOI:10.1017/S0022215121000876 (Source: Journal of Laryngology and Otology)
Source: Journal of Laryngology and Otology - April 5, 2021 Category: ENT & OMF Authors: G Tirelli A Bertolin F Guida S Zucchini M Tofanelli G Rizzotto P Boscolo-Rizzo G Danesi N Gardenal Source Type: research
Genome characterization of zucchini yellow mosaic virus infecting cucurbits reveals the presence of a new genotype in Trinidad and Tobago in the Caribbean region
In this study, four ZYMV isolates infecting pumpkin in Trinidad and Tobago were characterized by complete genome sequencing. Phylogenetic analysis showed 5.9 –6.0% nt and 7.7–7.9% aa sequence divergence in comparison to the most closely related isolates NAT and AG from Israel and SE04T from Slovakia. Based on the variations in the complete genome sequence as well as individual gene sequences, a new genotype, designated ZYMV-Trini, is proposed for the se isolates. Among the gene sequences of ZYMV-Trini isolates, the greatest variation was observed in the HC-Pro gene, with 20.8% aa sequence divergence from their closest ...
Source: Archives of Virology - April 3, 2021 Category: Virology Source Type: research
Cancers, Vol. 13, Pages 1687: Margin Assessment in Soft Tissue Sarcomas: Review of the Literature
similiano De Paolis
Adequacy of margins must take into consideration both the resection margin width (quantity) and anatomic barrier (quality). There are several classification schemes for reporting surgical resection margin status for soft tissue sarcomas (STS). Most of the studies regarding treatment outcomes in STS included all histologic grades and histological subtypes, which include infiltrative and non-infiltrative subtypes and are very heterogeneous in terms of both histologic characteristics and treatment modalities (adjuvant treatments or not). This lack of consistency makes it difficult to compare results fr...
Source: Cancers - April 2, 2021 Category: Cancer & Oncology Authors: Andrea Sambri Emilia Caldari Michele Fiore Riccardo Zucchini Claudio Giannini Maria Giulia Pirini Paolo Spinnato Alberta Cappelli Davide Maria Donati Massimiliano De Paolis Tags: Review Source Type: research
Innovations strategy for moving from created regional clusters to co-creation in life sciences for health care and well-being ecosystems
Environ Sci Pollut Res Int. 2021 Mar 30. doi: 10.1007/s11356-021-13689-w. Online ahead of print.ABSTRACTOver the last decades, the demographic changes have all altered the population structure and influenced the social, economic, and political characteristics of countries over the world. Therefore, the creation of novel ecosystems, new clusters and systems which involved technology and industry, business, education, science, and innovation are increased rapidly. However, in order to solve the future global challenges, the created various types of clusters, public and private sector systems should cooperate and work togethe...
Source: Environmental Science and Pollution Research International - March 31, 2021 Category: Environmental Health Authors: Lina Draudviliene Zaneta Stasiskiene Kastytis Pamakstys Lina Surgaute Cecilia Maini Maria Gracia Zucchini Gudrum Mernitz S ławomir Sołtys Source Type: research
Adolescent males suffered from reduced physical activity and increased BMI during COVID- 19 pandemic
Publication date: Available online 27 March 2021Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Giulio Maltoni, Maximiliano Zioutas, Giuseppina Deiana, Giovanni Battista Biserni, Andrea Pession, Stefano Zucchini (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 27, 2021 Category: Nutrition Source Type: research
Adolescent males suffered from reduced physical activity and increased BMI during COVID- 19 pandemic
Lockdown due to COVID-19 pandemic has forced a decrease in physical activity (PA) and an increase in sedentary behavior (SB) and a possibly worsening of fat accumulation in already obese subjects. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - March 26, 2021 Category: Nutrition Authors: Giulio Maltoni, Maximiliano Zioutas, Giuseppina Deiana, Giovanni Battista Biserni, Andrea Pession, Stefano Zucchini Tags: Short Communication Source Type: research
Gender differences in weight gain during lockdown due to COVID-19 pandemic in adolescents with obesity
Lockdown due to COVID-19 pandemic has forced a decrease in physical activity (PA), an increase in sedentary behavior (SB) and a possibly worsening of fat accumulation in already obese subjects.The aim of this study was to investigate how social restriction may have contributed to weight changes in adolescents with obesity. Secondary aim was to evaluate possible parameters influencing weight changes. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - March 26, 2021 Category: Nutrition Authors: Giulio Maltoni, Maximiliano Zioutas, Giuseppina Deiana, Giovanni Battista Biserni, Andrea Pession, Stefano Zucchini Tags: Short Communication Source Type: research
IRF4 modulates the response to BCR activation in chronic lymphocytic leukemia regulating IKAROS and SYK
Leukemia, Published online: 23 February 2021; doi:10.1038/s41375-021-01178-5IRF4 modulates the response to BCR activation in chronic lymphocytic leukemia regulating IKAROS and SYK (Source: Leukemia)
Source: Leukemia - February 23, 2021 Category: Hematology Authors: Rossana Maffei Stefania Fiorcari Stefania Benatti Claudio Giacinto Atene Silvia Martinelli Patrizia Zucchini Leonardo Potenza Mario Luppi Roberto Marasca Source Type: research
