Population Dietary Salt Reduction and the Risk of Cardiovascular Disease. A Scientific statement from the European Salt Action Network
Publication date: Available online 7 December 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): F.P. Cappuccio, M. Beer, P. Strazzullo, European Salt Action NetworkAbstractThe publication in the last few years of a number of prospective observational studies suggesting a J-shaped association between levels of salt (sodium) consumption and cardiovascular outcomes has opened a debate on the pertinence of population-wide salt reduction policies to reduce cardiovascular disease burden, and some have even questioned the global World Health Organization guidelines, that recommend a 30% reduction in salt con...
Source: Nutrition, Metabolism and Cardiovascular Diseases - December 7, 2018 Category: Nutrition Source Type: research

The Effects of Folic Acid Supplementation on C-Reactive Protein: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Publication date: Available online 6 December 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Fatahi S, Pezeshki M, S.M. Mousavi, Teymouri A, Rahmani J, Kord Varkaneh H, Ghaedi EAbstractBackground and aimGiven the contradictory results of previous randomized controlled trials (RCTs), we performed systematic review and met-analysis to quantify and summarize the effects of folic acid supplementation on C- reactive protein (CRP).Methods and resultsWe performed a systematic search of all available RCTs conducted up to October 2018 in the following databases: PubMed, Scopus, and Cochrane. RCTs which inve...
Source: Nutrition, Metabolism and Cardiovascular Diseases - December 6, 2018 Category: Nutrition Source Type: research

Leptin levels predict the development of insulin resistance in a sample of adult men–The Olivetti Heart Study
Publication date: Available online 13 October 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): L. D'Elia, P. Strazzullo, R. Iacone, O. Russo, F. GallettiAbstractBackground and aimsLeptin (LPT) is associated with unfavourable cardio-metabolic risk profile. Although a number of studies have found a positive association between LPT and insulin resistance (IR), no observational study has evaluated a prospective association to detect a predictive role of LPT in IR. Therefore, the aim of this study was to estimate the role of LPT on the incidence of IR in an 8-year follow-up of a sample of adult men (The O...
Source: Nutrition, Metabolism and Cardiovascular Diseases - December 5, 2018 Category: Nutrition Source Type: research

Ferritin levels throughout childhood and metabolic syndrome in adolescent stage
Publication date: Available online 4 December 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): M.F. Suárez-Ortegón, E. Blanco, S. McLachlan, J.M. Fernandez-Real, R. Burrows, S.H. Wild, B. Lozoff, S. GahaganAbstractBackground and aimIncreased ferritin levels have been widely associated with cardiovascular risk in adults. Whether ferritin levels and their changes during childhood are related to metabolic syndrome (MetS) at adolescence is unknown. We aimed to evaluate these associations using levels of ferritin at 5, 10 and 16 years and their linear increases and patterns of sustained incr...
Source: Nutrition, Metabolism and Cardiovascular Diseases - December 5, 2018 Category: Nutrition Source Type: research

Myocardial hypertrophy induced by high salt consumption is prevented by angiotensin II AT2 receptor agonist
ConclusionCompound 21 prevented the development of cardiac hypertrophy and fibrosis, reduced the increase in blood pressure and prevented the lower weight gain in animals fed a high salt diet. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - December 2, 2018 Category: Nutrition Source Type: research

Effects of pre- or post-exercise whey protein supplementation on body fat and metabolic and inflammatory profile in pre-conditioned older women: a randomized, double-blind, placebo-controlled trial
The objective of this study was to investigate the effect of whey protein (WP) pre- or post-RT on metabolic and inflammatory profile in pre-conditioned older women.Methods and ResultsSeventy older women participated in this investigation and were randomly assigned to one of three groups: WP pre-RT and placebo post-RT (WP-PLA, n = 24), placebo pre-RT and WP post-RT (PLA-WP, n = 23) and placebo pre and post-RT (PLA-PLA, n =23). Each group ingested 35 g of PLA or WP pre- and post-RT. RT was carried out over 12 weeks (three times/week; 3 x 8–12 repetition maximum). Body composition, blood pressure, blood samples and diet...
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 30, 2018 Category: Nutrition Source Type: research

Severe hypercholesterolaemia in a paediatric patient with congenital analbuminaemia
Publication date: Available online 24 November 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): S. D’Addato, F. Fogacci, A.F.G. Cicero, S. Palmisano, F. Baronio, C. Biagi, C. Borghi (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 24, 2018 Category: Nutrition Source Type: research

Ultra-processed food consumption and its effects on anthropometric and glucose profile: a longitudinal study during childhood
ConclusionOur data suggest that early ultra-processed food consumption played a role in increasing abdominal obesity in children. These results reinforce the importance of effective strategies to prevent the excessive consumption of ultra-processed foods, especially in early ages. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 22, 2018 Category: Nutrition Source Type: research

A two-year study of parental obesity status and childhood obesity in China
Publication date: Available online 20 November 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): R.Y. Xu, Y.Q. Zhou, X.M. Zhang, Y.P. Wan, X. GaoAbstractBackground and AimsWe evaluated the association between parental obesity and their children’s obesity parameters [e.g., percentage of body fat (PBF)] over time.Methods and ResultsThe study included 2,066 Chinese parents-children trios (n=1,001 girls and 1,065 boys, aged 6-14 years). Children’s height, weight, waist circumference (WC) and PBF (bioelectrical impedance analysis) were annually assessed from 2014 (baseline) to 2016. Information...
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 21, 2018 Category: Nutrition Source Type: research

Editorial Board
Publication date: December 2018Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 28, Issue 12Author(s): (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 17, 2018 Category: Nutrition Source Type: research

Associations of metabolically healthy obesity with prevalence and progression of coronary artery calcification: Results from the Heinz Nixdorf Recall Cohort Study
ConclusionOur analyses on MHO CAC associations add to the evidence that MHO is not a purely benign health condition. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 16, 2018 Category: Nutrition Source Type: research

Editorial Board
Publication date: November 2018Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 28, Issue 11Author(s): (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 9, 2018 Category: Nutrition Source Type: research

Identifying sources of measurement error in assessing dietary intakes – Results of a multi-country ring-trial
ConclusionIn a design that eliminated respondent bias, this study indicates that softwares, supporting databases and interviewers generally introduce random error in dietary assessments. The inclusion of large sample sizes and food pictures to quantify portions, together with enhanced attention on interviewers’ training, standardisation of procedures and regular tool upgrades are essential in assuring a study’s quality and comparability. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 9, 2018 Category: Nutrition Source Type: research

Review of general suggestions on physical activity to prevent and treat gestational and pre-existing diabetes during pregnancy and in postpartum
Publication date: Available online 8 November 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): N. Di Biase, S. Balducci, C. Lencioni, A. Bertolotto, A. Tumminia, A.R. Dodesini, B. Pintaudi, T. Marcone, E. Vitacolonna, A. NapoliAbstractThe aim of this review is to provide general suggestions about physical activity (PA) in pre-gestational and gestational diabetes (GDM) and encourage women to take part in safe and effective activities throughout pregnancy, in the absence of other contraindications. Physical activity before, during pregnancy and postpartum has many positive effects on the mother as it c...
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 9, 2018 Category: Nutrition Source Type: research

Diabetes and work: the need of a close collaboration between diabetologist and occupational physician
ConclusionsFurther studies are necessary to define workplace-based interventions, which should be minimally invasive towards the work organization, allowing diabetic workers to fully realize their work skills while improving their wellbeing at work. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 9, 2018 Category: Nutrition Source Type: research

Role of socio-economic status in observational studies: a study model on non-alcoholic steato-hepatitis (NASH)
Publication date: Available online 1 November 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Nobili Valerio, Mosca Antonella, Silano Marco, Agostoni Carlo (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 3, 2018 Category: Nutrition Source Type: research

Weight loss facilitates reduction of left ventricular mass in obese hypertensive patients: the Campania Salute Network
Publication date: Available online 1 November 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): M.T. Lønnebakken, C. Mancusi, M.A. Losi, E. Gerdts, R. Izzo, M.V. Manzi, N. De Luca, G. de Simone, B. TrimarcoAbstractBackground and aimsReduction of left ventricular mass index (LVMi) during antihypertensive treatment is less likely to occur in obese subjects. The aim of the study was to assess whether weight loss influences reduction of LVMi in treated, obese, hypertensive patients.Methods and resultsFrom the Campania Salute Network registry, we identified 1546 obese hypertensive patients (50&plusm...
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 3, 2018 Category: Nutrition Source Type: research

High prevalence of non-alcoholic fatty liver disease and metabolic risk factors in Guatemala: A population-based study
ConclusionsThe prevalence of metabolic abnormalities and liver outcomes in this general population study was very high. The prevalence of metabolic and liver abnormalities was particularly high among women, an observation that could explain the atypical 1:1 male to female ratio of liver cancer in Guatemala. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - November 1, 2018 Category: Nutrition Source Type: research

Lifestyle, anthropometric, socio-demographic and perinatal correlates of childhood hypertension: The Healthy Growth Study
ConclusionsChildren not born large for their gestational age, with low MVPA, low SES, being overweight, or obese and with family history of hypertension, have higher risk of childhood hypertension. Future studies should confirm the present findings so that the identified correlates of childhood hypertension can be used by public health initiatives for early detection and management of this major public health problem, prioritizing children and families at the highest possible risk for hypertension. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 26, 2018 Category: Nutrition Source Type: research

Serum dietary fatty acids and coronary heart disease risk – a nested case-control-study within the CARLA cohort
ConclusionOur results support the conclusion that in populations with a homogenous low level of omega-3 polyunsaturated fatty acids consumption, serum fatty acid levels are not associated with CHD risk. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 26, 2018 Category: Nutrition Source Type: research

Circulating Pro-Neurotensin in gestational diabetes mellitus
Conclusions/interpretation: Circulating Pro-NT is not independently associated with GDM, but is with HOMA-IR, creatinine, and FFA even after adjustment for pregnancy status. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 21, 2018 Category: Nutrition Source Type: research

Fetal cardiac growth is associated with in utero gut colonization
ConclusionFetal cardiac growth and gut colonization are associated. Greater neonatal LVPW thickness is related to lower diversity of the gut microbiota community, with depletion of bacteria having anti-remodeling effects, and enrichment in bacteria functionally linked to inflammation. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 20, 2018 Category: Nutrition Source Type: research

Effects of Postoperative Dietary Intake on Functional Recovery of Patients Undergoing Cardiac Surgery
Publication date: Available online 19 October 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): M. Ogawa, K.P. Izawa, S. Satomi-Kobayashi, Y. Tsuboi, K. Komaki, Y. Gotake, N. Yoshida, K. Wakida, J. Uchida, Y. Sakai, Y. OkitaAbstractBackground and aimAmong elderly patients undergoing cardiac surgery, malnutrition is very common and related to muscle wasting known as sarcopenia. Cardiac surgery causes a further decline of nutritional status due to reduced dietary intake (DI); however, the impact of postoperative DI on functional recovery is unclear.Methods and ResultsWe enrolled 250 consecutive patients...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 20, 2018 Category: Nutrition Source Type: research

Clinical and subclinical cardiovascular disease in female SLE patients: interplay between body mass index and bone mineral density
This study aims to analyze the associations of subclinical atherosclerosis with traditional and non-traditional CV risk factors.Methods and ResultsIn a cross-sectional study, atherosclerosis burden was compared between 112 female SLE patients and 31 controls. Plaque number and carotid intima-media wall thickness (cIMT) were assessed by ultrasonography. In a retrospective study, BMD determinations obtained 5-years before the ultrasonography assessment were analyzed in a subgroup of 62 patients. Plaque frequency was increased in SLE, even in patients without CV events or carotid wall thickening. cIMT was increased in patient...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 16, 2018 Category: Nutrition Source Type: research

The dose-response effects of uric acid on the prevalence of metabolic syndrome and electrocardiographic left ventricular hypertrophy in healthy individuals
Publication date: Available online 16 October 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Cheng-Wei Liu, Ko-Hung Chen, Chin-Kun Tseng, Wei-Cheng Chang, Yen-Wen Wu, Juey-Jen HwangAbstractBackground and aimHyperuricemia(HUA) is associated with the prevalence of metabolic syndrome(MetS) and cardiovascular risks in various populations. HUA is also able to induce cardiomyocyte hypertrophy in mouse models. However, the dose-response effects of serum uric acid(SUA) on the prevalence of MetS and electrocardiographic left ventricular hypertrophy(LVH) are unclear.Methods and resultsWe retrospectively coll...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 16, 2018 Category: Nutrition Source Type: research

Leptin Levels Predict The Development of Insulin Resistance In A Sample Of Adult Men - The Olivetti Heart Study
Publication date: Available online 13 October 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): L. D’Elia, P. Strazzullo, R. Iacone, O. Russo, Fd GallettiAbstractBackground and AimsLeptin (LPT) is associated with unfavourable cardio-metabolic risk profile. Although a number of studies have found a positive association between LPT and insulin resistance (IR), no observational study has evaluated a prospective association to detect a predictive role of LPT in IR. Therefore, the aim of this study was to estimate the role of LPT on the incidence of IR in an 8-year follow-up of a sample of adult men ...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 14, 2018 Category: Nutrition Source Type: research

Dietary Weight Loss in Insulin-resistant Non-obese Humans: Metabolic Benefits and Relationship to Adipose Cell Size
ConclusionsWeight loss yields metabolic health benefits in insulin-resistant overweight adults, even in the absence of classic cardiovascular risk factors. Weight loss-related improvement in insulin sensitivity may be mediated through changes in adipose cell size and/or central distribution of body fat. The insulin-resistant subgroup of overweight individuals should be identified and targeted for dietary weight loss.Clinical Trials IdentifierNCT00186459. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 13, 2018 Category: Nutrition Source Type: research

The Effect of Camelina Sativa Oil And Fish Intakes on Fatty Acid Compositions of Blood Lipid Fractions
Publication date: Available online 11 October 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): S. Manninen, M. Lankinen, V. de Mello, J. Ågren, D. Laaksonen, U. Schwab, A. ErkkiläAbstractBackground and AimsBlood lipid fractions serve as objective biomarkers of dietary fat intake. It is unclear which fatty acid pool most accurately reflects the dietary intakes of different n-3 PUFAs. We aimed to investigate the effect of fish and camelina sativa oil (CSO) intakes on fatty acid composition of erythrocyte membranes (EM), plasma phospholipids (PL), cholesteryl esters (CE) and triglycerides (TG...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 13, 2018 Category: Nutrition Source Type: research

The association between subclinical inflammation and abnormal glucose and lipid metabolisms in normal-weight Korean individuals
Publication date: Available online 25 June 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): M.-H. Kim, H.-N. Kim, W.-S. ChoiAbstractBackgrounds and AimsWe aimed to reveal the association between subclinical inflammation and metabolic risk factors and to determine the difference in the association between normal-weight and obese Korean individuals.Methods and ResultsData collected from the Korean National Health and Nutrition Examination Survey (KNHANES) 2015, conducted from January to December 2015, were analyzed. Overall, 4620 subjects were examined and divided into two subgroups: 2987 and 1633 subj...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

Ethnic differences in metabolic cardiovascular risk among normal weight individuals: implications for cardiovascular risk screening. The HELIUS study
ConclusionEven among normal weight individuals, high cardiovascular metabolic risk is more common among ethnic minorities than among the majority population. Regardless of ethnicity, most normal weight individuals with increased risk are eligible for cardiovascular risk screening. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

Caloric restriction attenuates aging-induced cardiac insulin resistance in male Wistar rats through activation of PI3K/Akt pathway
ConclusionIn conclusion CR partially improves cardiac insulin sensitivity and prevents the aging induced decrease in myocardial contractility in response to insulin administration through activation of PI3K/Akt pathway. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

Lipoprotein-X fifty years after its original discovery
Publication date: Available online 26 September 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): R. Fellin, E. ManzatoAbstractThe conversion of cholesterol to bile acids is regulated by several mechanisms including cholesterol 7 alpha hydroxylase, fibroblast growth factor 19, and farnesoid X receptors. During cholestasis these mechanisms are altered and there is an accumulation of bile acids and cholesterol in plasma. The hypercholesterolemia observed in cholestasis is due to the presence of an anomalous lipoprotein called lipoprotein-X (Lp-X).Lp-X is a lipoprotein rich in phospholipid and free chole...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

Association between long-term exposure of ambient air pollutants and cardiometabolic diseases: A 2012 Korean Community Health Survey
Publication date: Available online 26 September 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Jinyoung Shin, Jaekyung Choi, Kyoung Jin KimAbstractBackground and AimThe associations between long-term exposure to particulate matter
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults
ConclusionsSubjects with High-GRS may be susceptible to increased insulin resistance by 50% and its risk may be exacerbated by consuming more than 10 cups coffee/week or 220 mg caffeine/day. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

The Impact Of A Nutritional Intervention Based On Egg White For Phosphorus Control In Hemodialyis Patients
Publication date: Available online 28 September 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Bruna Guida, Sara Parolisi, Mario Coco, Tiziana Ruoppo, Roberta Veccia, Rossella Trio, Andrea Memoli, Mauro CataldiAbstractBackground and aimsHere we describe a dietary intervention for hyperphosphatemia in dialysis patients based on the partial replacement of meat and fish, which are one of the main sources of alimentary phosphorous, with egg white, a virtually phosphorous-free protein source. This intervention aims to reduce phosphorous intake without causing protein wasting.Patients and Methods23 hyper...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

Total polyphenol intake, polyphenol subtypes and incidence of cardiovascular disease: The SUN cohort study
ConclusionThe intake of flavonoids showed an inverse association with risk of cardiovascular events in a prospective cohort of Spanish middle-aged adult university graduates.Registration number for clinical trialsNCT02669602 in Clinical Trials. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

Correct determination of glycemia in the diagnosis and management of diabetes: recommendations for the optimization of the pre-analytical phase
Publication date: Available online 4 October 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Graziella Bonetti, Mariarosa Carta, Annunziata Lapolla, Roberto Miccoli, Roberto Testa, Andrea Mosca, SIBioC-SIPMeL working group on Diabetes (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2018 Category: Nutrition Source Type: research

Gender differences in homocysteine concentrations, a population-based cross-sectional study
Publication date: Available online 21 September 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): E. Cohen, I. Margalit, T. Shochat, E. Goldberg, I. KrauseAbstractBackground and aimsHigh concentrations of homocysteine are considered a risk factor for atherosclerosis and coronary artery disease. The aim of this study was to assess whether or not there are gender differences in the plasma concentrations of homocysteine.Methods and resultsData were collected from medical records of individuals examined at a screening center in Israel between the years 2000-2014. Cross sectional analysis was carried out o...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 22, 2018 Category: Nutrition Source Type: research

Arginine bioavailability and endothelin-1 system in the regulation of vascular function of umbilical vein endothelial cells from intrauterine growth restricted newborns
ConclusionsThe present study demonstrated that the reduction of NO bioavailability and release results from elevated Arg-2, accumulation of intracellular ADMA, and imbalance of ET-1 and ETBR, further leading to IUGR-associated vascular endothelial dysfunction. Our study provided novel evidence on the mechanism underlying fetal programming associated with IUGR, which will serve as potential therapeutic targets in the prevention of adverse cardiovascular consequences in adulthood.Graphical abstract (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 22, 2018 Category: Nutrition Source Type: research

Long-term effects of coffee and caffeine intake on the risk of pre-diabetes and type 2 diabetes: Findings from a population with low coffee consumption
Publication date: Available online 12 September 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Parvin Mirmiran, Mattias Carlström, Zahra Bahadoran, Fereidoun AziziAbstractBackground and aimHere, we examined the potential effect of coffee consumption and total caffeine intake on the occurrence of pre-diabetes and T2D, in a population with low coffee consumption.MethodsAdults men and women, aged 20-70 years, were followed for a median of 5.8 y. Dietary intakes of coffee and caffeine were estimated using a 168-food items validate semi-quantitative food frequency questionnaire, at baseline. Cox pr...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 12, 2018 Category: Nutrition Source Type: research

Editorial Board
Publication date: October 2018Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 28, Issue 10Author(s): (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 9, 2018 Category: Nutrition Source Type: research

Adipose tissue polyunsaturated fatty acids and metabolic syndrome among adult parents and their children
ConclusionsAmong Mesoamerican adults, MetS prevalence is inversely associated with adipose tissue ALA and GLA, and positively associated with EPA, DGLA, and the D6D index. Among children, metabolic risk score is positively associated with DPA, DGLA, and the D6D index. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 6, 2018 Category: Nutrition Source Type: research

Preclinical Signs Of Liver And Cardiac Damage In Youth With Metabolically Healthy Obese Phenotype
Publication date: Available online 4 September 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): P. Di Bonito, E. Miraglia del Giudice, C. Chiesa, M.R. Licenziati, M. Manco, F. Franco, G. Tornese, M.G. Baroni, A. Morandi, C. Maffeis, L. Pacifico, G. Valerio, CARITALY Study, Childhood Obesity Study Group of the Italian Society of Pediatric Endocrinology and DiabetologyAbstractBackground and AimsWe aimed to evaluate whether the metabolically healthy obese (MHO) phenotype was associated with hepatic steatosis (HS) or left ventricular hypertrophy (LVH) in young people with overweight (OW), obesity (OB) an...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 5, 2018 Category: Nutrition Source Type: research

Is lower low-density lipoprotein cholesterol associated with lower androgen and erectile dysfunction in men?
ConclusionLower LDL-C levels were significantly associated with lower free T and lower FAI in a general population of men. Moreover, both low and high levels of LDL-C might be risk factors for ED. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 2, 2018 Category: Nutrition Source Type: research

Comparison of a Mediterranean to a low-fat diet intervention in adults with type 1 diabetes and metabolic syndrome: A 6–month randomized trial
ConclusionsThis study suggests that a 6-month non-restrictive dietary intervention in patients with T1D and MS could contribute to weight management, without significant differences between interventions for anthropometric and metabolic parameters. Further studies should investigate the long-term benefits of these diets.Clinical Trial RegistryNCT02821585 (https://clinicaltrials.gov/) (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 31, 2018 Category: Nutrition Source Type: research

Inflammation and ventricular-vascular coupling in hypertensive patients with metabolic syndrome
Publication date: Available online 23 August 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): L. Zanoli, A. Di Pino, V. Terranova, S. Di Marca, M. Pisano, R. Di Quattro, V. Ferrara, R. Scicali, A.M. Rabuazzo, P. Fatuzzo, P. Castellino, S. Piro, F. Purrello, L. MalatinoAbstractBackground and AimsMetabolic syndrome (MetS) is currently considered to raise the risk for type 2 diabetes and cardiovascular events. It has been suggested that part of this risk excess may be due to a cluster of additional factors associated with MetS. We aimed to investigate the role of inflammation on the ventricular-vascular...
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 24, 2018 Category: Nutrition Source Type: research

(−)-epicatechin inhibits development of dilated cardiomyopathy in δ sarcoglycan null mouse
ConclusionAll the results indicate that (−)-epicatechin has the potential to prevent the development of dilated cardiomyopathy of genetic origin and encourages the use of this flavonol as a pharmacological therapy for dilated cardiomyopathy and heart failure diseases. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 23, 2018 Category: Nutrition Source Type: research

Light wine consumption is associated with a lower odd for cardiovascular disease in chronic kidney disease
Publication date: Available online 22 August 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): T. Jespersen, N. Kruse, T. Mehta, M. Kuwabara, L. Noureddine, D. JalalAbstractAimsTo examine the association between wine consumption and the prevalence of chronic kidney disease (CKD) and cardiovascular disease (CVD).Data synthesisWe performed a cross-sectional logistic regression analysis of National Health and Nutrition Examination Survey (NHANES) in participants 21 years of age or older from 2003 to 2006 in a large representative study of the U.S. population. Wine consumption was categorized as none (0 g...
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 23, 2018 Category: Nutrition Source Type: research

Weight loss but not gains in cardiorespiratory fitness after exercise-training predicts improved health risk factors in metabolic syndrome
Publication date: Available online 23 August 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Ricardo Mora-Rodriguez, Juan Fernando Ortega, Felix Morales-Palomo, Miguel Ramirez-JimenezAbstractBackground and AimsTo examine the relationship between changes in cardiorespiratory fitness (CRF; estimated by VO2max) and metabolic syndrome (MetS) after an exercise training intervention to confirm/contradict the high association found in cross-sectional observational studies.Methods and ResultsMetS individuals (54±8 yrs old; BMI of 32±5) were randomly allocated (6:1 ratio) to a group that exerci...
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 23, 2018 Category: Nutrition Source Type: research

Prevalence of the cardiovascular health status in adults: a systematic review and meta-analysis
ConclusionThe prevalence of ideal status was low for some metrics, such as dietary pattern, and the overall CVH status was still unsatisfactory. We should continue to measure the CVH status and carry out lifestyle interventions to improve the CVH status in the whole population. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 21, 2018 Category: Nutrition Source Type: research