Physical activity attenuates the association between the IRS1 genotype and childhood obesity in Chinese children
Publication date: Available online 18 May 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Q.Y. Song, J.Y. Song, C.X. Li, Z. Liu, Yang Wang, L. Qi, Yan Wang, H.J. WangAbstractBackgrounds and Aims: The insulin receptor substrate 1 (IRS1) rs2943650 was found to be associated with obesity in adults, but the association has not been evaluated in children. The present study aimed to examine whether IRS1 rs2943650 was associated with obesity in Chinese children, and explore the interaction between rs2943650 and physical activity.Methods and resultsIRS1 rs2943650 was genotyped in 3303 Chinese children aged ...
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 20, 2019 Category: Nutrition Source Type: research

Associations between anthropometric indicators in early life and low-grade inflammation, insulin resistance and lipid profile in adolescence
ConclusionA high BMI from an early age was consistently associated with worse inflammatory and lipid profiles and insulin resistance in adolescence. No associations were found between BW and the same studied outcomes. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 19, 2019 Category: Nutrition Source Type: research

Prevalence of Obesity and Obesity-Associated Muscle Wasting In Patients on Peritoneal Dialysis
Publication date: Available online 16 May 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Bruna Guida, Rossella Trio, Martina Di Maro, Andrea Memoli, Teresa Di Lauro, Annamaria Belfiore, Mariarosaria Santillo, Mauro CataldiAbstractBackground and AimsA progressive decrease in muscle mass till full blown sarcopenia may occur in peritoneal dialysis (PD) patients and worsen their life quality and expectancy. Here we investigate the prevalence of obesity and obesity-associated muscle wasting in PD patients.Patients and MethodsStudy design was observational, cross sectional. Body composition was assessed ...
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 17, 2019 Category: Nutrition Source Type: research

Dietary fat intake and Metabolic Syndrome in adults: a systematic review
ConclusionsThe effects of dietary SFAs on MetS will be influenced by other specific nutrients. Replacement of SFA by MUFA and PUFA has been associated with MetS decrease. Dietary recommendations should emphasize on different quality of fat intake and not only to reduce total fat intake to obtain health benefits in adults. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 17, 2019 Category: Nutrition Source Type: research

The relationship between Serum Levels of Immunoglobulins and Metabolic Syndrome in an Adult Population: A population study from the TCLSIH cohort study
ConclusionsThis study demonstrated that decreased IgG and increased IgA are independently related to a higher prevalence of MetS. The results indicate that the immunoglobulins might be useful predictive factors for MetS in the general adult population. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 16, 2019 Category: Nutrition Source Type: research

Effects of Ramadan intermittent fasting on lipid and lipoproteins parameters: An updated meta-analysis
ConclusionRamadan fasting may be accompanied by a moderate improvement of lipid and lipoprotein parameters, especially HDL-C levels; fasting appears to be more beneficial for men and athletic subjects. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 16, 2019 Category: Nutrition Source Type: research

Evaluation of Body Composition in Renal Transplant Patients: an unsolved problem
Publication date: Available online 14 May 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Massimo Sabbatini, Bruna Guida (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 14, 2019 Category: Nutrition Source Type: research

Putative Nox2 Inhibitors Worsen Homocysteine-Induced Impaired Acetylcholine-Mediated Relaxation
Publication date: Available online 11 May 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Renee M. Smith, Sudarshan Rai, Peter Kruzliak, Alan Hayes, Anthony ZulliAbstractBackgroundIncreased homocysteine (Hcy) is associated with coronary artery disease (CAD). Hcy increases reactive oxygen species (ROS) via NADPH oxidases (Nox), reducing acetylcholine-mediated vasorelaxation. We aimed to determine if putative Nox2 inhibitors prevent Hcy-impaired acetylcholine-mediated vasorelaxation.MethodsNew Zealand White rabbit and wild-type (C57BL/6) and Nox2-/- (NOX) mice aortic rings were mounted in organ baths....
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 13, 2019 Category: Nutrition Source Type: research

Body mass index and body fat distribution and new-onset atrial fibrillation: Substudy of the European Prospective Investigation into Cancer and Nutrition in Norfolk (EPIC-Norfolk) study
Publication date: Available online 15 March 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): J. Neefs, S.M. Boekholdt, K.-T. Khaw, R. Luben, R. Pfister, N.J. Wareham, E.R. Meulendijks, P. Sanders, J.R. de GrootAbstractBackground and aimObesity is a recognized risk factor for new-onset atrial fibrillation (AF). The association between body fat distribution, which is measured by body mass index (BMI) and waist–hip ratio (WHR), its changes, and new-onset AF is conflicting.Methods and resultsParticipants of the European Prospective Investigation into Cancer and Nutrition in Norfolk cohort study wer...
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 10, 2019 Category: Nutrition Source Type: research

Assessment of the American Heart Association's “Life's simple 7” score in French-speaking adults from Québec
Publication date: Available online 16 March 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): S. Harrison, C. Couillard, J. Robitaille, M.-C. Vohl, M. Bélanger, S. Desroches, V. Provencher, R. Rabasa-Lhoret, L. Bouchard, M.-F. Langlois, J. Houle, S. Lemieux, B. LamarcheAbstractBackground and aimsThe “Life's Simple 7” (LS7) metrics were developed by the American Heart Association (AHA) to assess and promote cardiovascular health in the American population. The purpose of this study was to assess the overall cardiovascular health of French-speaking adults from the Province of Quebec u...
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 10, 2019 Category: Nutrition Source Type: research

Long term association of nut consumption and cardiometabolic risk factors
ConclusionAfter adjustment for potential confounders, inverse association for nut consumption and obesity, but positive association for diabetes and nut intake was observed. Based on our findings, nuts incorporation into people’s usual diet may have beneficial effects for individuals with lower risk, such as non-diabetic subjects. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 10, 2019 Category: Nutrition Source Type: research

Markers of iron status, blood pressure and incident hypertension among Chinese adults
ConclusionThe current study found that haemoglobin and transferrin levels were positively associated with blood pressure and incident hypertension. Further research in different ethnic groups is required to confirm the association of the full range of markers of iron with BP and incident hypertension. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 8, 2019 Category: Nutrition Source Type: research

Impact of Severe and Symptomatic Hypoglycemia on Quality of Life and Fear of Hypoglycemia in Type 1 and Type 2 Diabetes. Results of the Hypos-1 Observational Study
ConclusionNot only severe but also symptomatic hypoglycemia negatively affect patient QoL, especially in T2DM. Addressing fear of hypoglycemia should be a goal of diabetes education. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 7, 2019 Category: Nutrition Source Type: research

Serum Long-Chain n-3 Polyunsaturated Fatty Acids and Aortic Calcification in Middle-Aged Men: The Population-Based Cross-sectional ERA-JUMP Study
ConclusionsThis study showed the significant inverse association of LCn-3PUFAs with aortic calcification independent of conventional cardiovascular risk factors among men in the general population. This association appeared to be driven by DHA but not EPA. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 7, 2019 Category: Nutrition Source Type: research

Body Composition and nutritional therapy in renal transplant patients
Publication date: Available online 7 May 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Leonardo Spatola, Elena Dozio (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 7, 2019 Category: Nutrition Source Type: research

Relationship of a Body Shape Index and Body Roundness Index, with carotid atherosclerosis in arterial hypertension
Publication date: Available online 7 May 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Giulio Geraci, Marta Zammuto, Rossella Gaetani, Alessandro Mattina, Francesco D’Ignoto, Calogero Geraci, Davide Noto, Maurizio Averna, Santina Cottone, Giuseppe MulèAbstractBackground and AimsA Body Shape Index (ABSI) and Body Roundness Index (BRI) are two; new anthropometric adiposity indices that have shown to be associated better than BMI with adipose abdominal tissue, with the onset of diabetes and the risk of premature death. Little is known about the influence of ABSI and BRI on subclinical va...
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 7, 2019 Category: Nutrition Source Type: research

Soy isoflavones (from Glycine max) preserves hepatocellular free radical defense system potential and ameliorates inflammatory response in high fat fed ovariectomised Wistar rats: The molecular mechanisms
Publication date: Available online 4 May 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): P. Sankar, P. Rajaa Muthu, Zachariah Bobby, M.G. SridharAbstractPostmenopausal women are more prone to develop metabolic syndrome (MetS) components; insulin resistance, type2 diabetes, dyslipidemia, atherosclerosis and obesity than premenopausal women. Oxidative stress (OxS) and inflammation (INF) are emerged as major triggers for these metabolic consequences. However, the pathogenesis of OxS and inflammation after menopause is only partially understood which is yet to be elucidated. The lack of safe/effective c...
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 5, 2019 Category: Nutrition Source Type: research

Breakfast association with arterial stiffness and carotid atherosclerotic burden. Insights from the ‘Corinthia’ study
Publication date: Available online 2 May 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Evangelos Oikonomou, George Lazaros, Evangelia Christoforatou, Christos Chasikidis, Georgina Vavouranaki, Georgia Vogiatzi, George Angelos Papamikroulis, Sotirios Tsalamandris, Georgios Gergiopoulos, Savvas Mazaris, Panagiotis Theofilis, Myriam Anastasiou, Nikos Galiatsatos, Dimitris TousoulisAbstractBackground and AimsΤhe role of dietary patterns, in cardiovascular diseases has been challenged. The role of breakfast as an element of balance energy intake has gained research interest. However, the effects of...
Source: Nutrition, Metabolism and Cardiovascular Diseases - May 3, 2019 Category: Nutrition Source Type: research

Association of elective cesarean delivery with metabolic measures in childhood: a prospective cohort study in China
Publication date: Available online 30 April 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Y.-B. Zhou, H.-T. Li, K.-Y. Si, Y.-L. Zhang, L.-L. Wang, J.-M. LiuAbstractBackground and AimsCesarean delivery may increase the risk of childhood obesity, a precursor of metabolic syndrome (MetS). We aimed to investigate the association of elective cesarean delivery (ElCD) with MetS and its components in a Chinese birth cohort.Methods and ResultsThis cohort included 1467 children (737 delivered by ElCD and 730 by spontaneous vaginal delivery [SVD]) who were followed up at 4–7 years of age in 2013. MetS ...
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 30, 2019 Category: Nutrition Source Type: research

Dietary assessment methods in surveillance systems targeted to adolescents: a review of the literature
ConclusionsThis study detected considerable variability across the systems identified, suggesting the need of a SURSYS targeted to adolescents that gathers as much as possible complete dietary information, with standardised methodology and regular periodicity. The detailed information provided by this review could be useful to national authorities for the choice of protocols to be applied in their own national surveys. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 30, 2019 Category: Nutrition Source Type: research

Association of serum proprotein convertase subtilisin/kexin type 9 with early atherosclerosis in newly diagnosed type 2 diabetes mellitus
Publication date: Available online 24 April 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Wen Guo, Yingyun Gong, Jie Li, Pei Qin, Jing Lu, Xiaona Li, WenfangZhu, Nianzhen Xu, Hongwen Zhou, Qun ZhangAbstractAimProprotein convertase subtilisin/kexin type 9 (PCSK9) is rapidly gaining attention as a potential risk of developing atherosclerosis due to its crucial role in the regulation of low-density lipoprotein cholesterol (LDL-C) metabolism. The present study investigated the relationship between serum PCSK9 levels and early atherosclerosis as assessed by carotid intimal-medial thickness (CIMT) and b...
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 25, 2019 Category: Nutrition Source Type: research

Editorial Board
Publication date: May 2019Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 29, Issue 5Author(s): (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 21, 2019 Category: Nutrition Source Type: research

Impact of Whole Egg Intake on Blood Pressure, Lipids and Lipoproteins in Middle-Aged and Older Population: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
ConclusionOverall, the results support the notion that quantity of whole egg intake does not affect CVD risk factors and consuming egg substitutes may also be beneficial compared to whole eggs on lowering CVD risk in the middle-aged and older population. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 20, 2019 Category: Nutrition Source Type: research

Statin Use and the Site-Specific Risk of Colorectal Cancer in Individuals with Hypercholesterolemia from the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS)
ConclusionsHigh statin users with hypercholesterolemia were associated with lower risk of overall colorectal cancer, especially proximal colon cancer in men and rectal cancer in both sexes. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 14, 2019 Category: Nutrition Source Type: research

Beneficial effects of non-quinazoline α1-adrenolytics on hypertension and altered metabolism in fructose-fed rats. A comparison with prazosin
Conclusionsα1–adrenoceptor blockade, endothelial protection, TNF-α suppressing and antioxidant activity together with favorable pharmacokinetic parameters determines high efficacy of MH-76, leading to the effective improvement of hemodynamic and metabolic disturbances in metabolic syndrome. The use of non-quinazoline, multiple-targeted α1-blockers may be an interesting option for treatment of hypertension with metabolic complications. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 14, 2019 Category: Nutrition Source Type: research

The Association Between Body Mass Index and In-hospital Outcome Among Patients with Acute Myocardial Infarction—Insights from China Acute Myocardial Infarction (CAMI) Registry
Publication date: Available online 11 April 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Chenxi Song, Rui Fu, Jingang Yang, Haiyan Xu, Xiaojin Gao, Lei Feng, Yang Wang, Xiaoxue Fan, Bin Ning, Shuping Wan, Kefei Dou, Yuejin Yang, CAMI Registry study group Beijing, China; MA, and NC, USAAbstractBackgroundThe relationship between body mass index (BMI) and in-hospital mortality risk among patients with acute myocardial infarction (AMI) remains controversial.MethodsWe included 35964 patients diagnosed with AMI in CAMI registry between January 2013 and December 2016. Patients were categorized into 4 gr...
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 11, 2019 Category: Nutrition Source Type: research

Evaluating the interaction of common FTO genetic variants, added sugar, and trans-fatty acid intakes in altering obesity phenotypes
This study aimed to investigate whether the association of changes in general and central obesity with added sugar and TFA intakes is modified by common fat mass and obesity-associated gene (FTO) polymorphisms, in isolation or in a combined-form genetic risk score (GRS).Methods and resultsSubjects of this cohort study were selected from among adult participants of the Tehran Lipid and Glucose Study (n = 4292, 43.2% male). Dietary data were collected using a valid and reliable food frequency questionnaire. The genotypes of selected polymorphisms (rs1421085, rs1121980, and rs8050136) were determined. Genetic risk s...
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 6, 2019 Category: Nutrition Source Type: research

Vegetarians have a lower fasting insulin level and higher insulin sensitivity than matched omnivores: A cross-sectional study
ConclusionVegetarian diet, especially vegan diet, is negatively associated with FI and IR, independent of BMI. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 6, 2019 Category: Nutrition Source Type: research

Effect of fitness on cardiac structure and function in overweight and obesity (the FATCOR study)
Publication date: Available online 3 April 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): H. Halland, K. Matre, E. Einarsen, H. Midtbø, S. Saeed, N. Pristaj, M.T. Lønnebakken, E. GerdtsAbstractAimsObesity is associated with reduced left ventricular (LV) systolic myocardial function. We aimed to explore whether this effect is offset in the presence of good fitness.DesignCross-sectional study.MethodsWe studied clinical and echocardiographic data from 469 overweight (body mass index [BMI]>27 kg/m2) and obese (BMI ≥30 kg/m2) women and men without known cardiovascular (CV) disease in...
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 4, 2019 Category: Nutrition Source Type: research

Italian Titration Approach Study (ITAS) with insulin glargine 300 U/mL in insulin-naïve type 2 diabetes: Design and population
Publication date: Available online 8 February 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): R.C. Bonadonna, A. Giaccari, R. Buzzetti, G. Aimaretti, D. Cucinotta, A. Avogaro, G. Perseghin, M. Larosa, G.B. Bolli, C.G. FanelliAbstractBackground and aimsFostering patient's self-managing of basal insulin therapy could improve glucose control, by removing patient's and physician's barriers to basal insulin initiation, titration and glucose monitoring. The Italian Titration Approaches Study (ITAS) aims at demonstrating non-inferiority (
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 3, 2019 Category: Nutrition Source Type: research

The use of real time continuous glucose monitoring or flash glucose monitoring in the management of diabetes: A consensus view of Italian diabetes experts using the Delphi method
Publication date: Available online 10 February 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): D. Bruttomesso, L. Laviola, A. Avogaro, E. Bonora, S. Del Prato, S. Frontoni, E. Orsi, I. Rabbone, G. Sesti, F. Purrello, of the Italian Diabetes Society (SID)AbstractUntil recently, in Italy, the use of continuous glucose monitoring (CGM) systems has been limited, but is now rapidly increasing, including the so-called real-time CGM (rtCGM) and the intermittently viewed CGM (iCGM), also called Flash Glucose Monitoring (FGM). These technologies overcome many of the limitations of self-monitoring of blood gl...
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 3, 2019 Category: Nutrition Source Type: research

Associations of macro and micronutrients and antioxidants intakes with preeclampsia: A case-control study in Jordanian pregnant women
ConclusionIn this case–control study in Jordanian pregnant women, preeclampsia was associated with a high intake of fat, saturated fat, and sodium and a low intake of fruits, fiber, vitamin C, B-carotene, and olive oil. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 2, 2019 Category: Nutrition Source Type: research

Effects of folic acid supplementation on C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
Publication date: Available online 6 December 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): S. Fatahi, M. Pezeshki, S.M. Mousavi, A. Teymouri, J. Rahmani, H. Kord Varkaneh, E. GhaediAbstractBackground and aimGiven the contradictory results of previous randomized controlled trials (RCTs), we performed a systematic review and meta-analysis to quantify and summarize the effects of folic acid supplementation on C-reactive protein (CRP).Methods and resultsWe performed a systematic search of all available RCTs conducted up to October 2018 in the following databases: PubMed, Scopus, and Cochrane. RCTs th...
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 31, 2019 Category: Nutrition Source Type: research

The Role Of Inflammation In The Association Between Overall And Visceral Adiposity And Subclinical Atherosclerosis
ConclusionOur results suggest that associations between measures of overall and visceral body fat and subclinical atherosclerosis are not mediated by inflammation as measured by CRP and GlycA. Obesity may exert cardiovascular risk via other markers of systemic inflammation. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 29, 2019 Category: Nutrition Source Type: research

Skeletal muscle mass in acute coronary syndrome prognosis: gender-based analysis from Hellenic Heart Failure cohort
ConclusionAU-shape association between SMI and 10-year CVD event especially in women was highlighted. This work reveals gender-specific remarks for “obesity-lean paradox” in secondary prevention, implying that high muscle mass accompanied by obesity and excess adiposity may not guarantee better prognosis.Graphical abstract (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 27, 2019 Category: Nutrition Source Type: research

Dietary acid load and risk of hypertension: a systematic review and dose-response meta-analysis of observational studies
ConclusionWe found a significant positive association between dietary acid load and hypertension. Further studies, particularly those with prospective nature, are needed to confirm our findings. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 25, 2019 Category: Nutrition Source Type: research

Methodological approach to the assessment of the obesogenic environment in children and adolescents: a review of the literature
ConclusionsThe questionnaires constructed and validated to analyze multiple constitutive elements of an obesogenic environment at the same time are complex and must be administered by qualified and trained staff. On the other hand, when two or more questionnaires are used to analyze different factors, the questionnaires used are generally shorter, self-administered, and generally easier to understand and interpret. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 22, 2019 Category: Nutrition Source Type: research

Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the predimed study
Publication date: Available online 21 March 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): P. Bazal, A. Gea, M.A. Martínez-González, J. Salas-Salvadó, E.M. Asensio, C. Muñoz-Bravo, M. Fiol, M.A. Muñoz, J. Lapetra, L.L. Serra-Majem, X. Pintó, J.I. González, N. Becerra-Tomás, M. Fitó, E. Ros, A. Alonso-Gómez, M. Ruiz-CanelaAbstractBackground and AimsThere is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterra...
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 22, 2019 Category: Nutrition Source Type: research

Longitudinal association of adiposity and high-sensitivity C-reactive protein from adolescence into early adulthood
ConclusionA significant longitudinal effect of the accumulation of adiposity on low-grade inflammation was observed. The change in adiposity from consecutive study waves was shown to have a stronger effect on final hsCRP concentrations than both previous adiposity and hsCRP levels. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 22, 2019 Category: Nutrition Source Type: research

Editorial Board
Publication date: April 2019Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 29, Issue 4Author(s): (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 22, 2019 Category: Nutrition Source Type: research

Assessment Of The American Heart Association’s “Life’s Simple 7” Score In French-Speaking Adults From Québec
Publication date: Available online 16 March 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): S. Harrison, C. Couillard, J. Robitaille, M.-C. Vohl, M. Bélanger, S. Desroches, V. Provencher, R. Rabasa-Lhoret, L. Bouchard, M.-F. Langlois, J. Houle, S. Lemieux, B. LamarcheAbstractBackground and aimsThe “Life’s Simple 7” (LS7) metrics were developed by the American Heart Association (AHA) to assess and promote cardiovascular health in the American population. The purpose of this study was to assess the overall CV health of French-speaking adults from the Province of Quebec using t...
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 17, 2019 Category: Nutrition Source Type: research

Body Mass Index and Body Fat Distribution and New-Onset Atrial Fibrillation. Sub study of The European Prospective Investigation Into Cancer and Nutrition in Norfolk (EPIC-Norfolk) Study
Publication date: Available online 15 March 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): J. Neefs, S.M. Boekholdt, K.-T. Khaw, R. Luben, R. Pfister, N.J. Wareham, E.R. Meulendijks, P. Sanders, J.R. de GrootAbstractBackgroundObesity is a recognized risk factor for new-onset atrial fibrillation (AF).The association between body fat distribution, measured by body mass index (BMI) and waist-hip ratio (WHR), its changes, and new-onset AF are conflicting.MethodsParticipants of the European Prospective Investigation into Cancer and Nutrition in Norfolk cohort study were included, with exclusion of preva...
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 16, 2019 Category: Nutrition Source Type: research

Notch3 signaling activation in smooth muscle cells promotes extrauterine growth restriction-induced pulmonary hypertension
ConclusionsThe present study demonstrated that upregulation of Notch3 signaling in PASMCs was crucial for the development of EUGR-induced PAH. Blocking Notch3-Hey1 signaling pathway in PASMCs provides a potential therapeutic target for PAH. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 14, 2019 Category: Nutrition Source Type: research

MicroRNA-24 attenuates vascular remodeling in diabetic rats through PI3K/Akt signaling pathway
ConclusionThe up-regulation of miR-24 significantly attenuated vascular remodeling both in balloon-injured diabetic rats and HG-stimulated VSMCs via suppression of proliferation, migration and collagen deposition by acting on PIK3R1 gene that modulated the PI3K/Akt/mTOR axes. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 14, 2019 Category: Nutrition Source Type: research

Dietary habits of adolescents living in North America, Europe or Oceania: a review on fruit, vegetable and legume consumption, sodium intake, and adherence to the Mediterranean Diet
ConclusionsAdolescents living in North America, Europe or Oceania are far from being compliant with the nutritional recommendations for fruit, vegetables, legumes, and sodium, and they do not follow the principles of the Mediterranean Diet. Educational and behavioural interventions are required to improve adolescents’ dietary patterns.Graphical abstract (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 14, 2019 Category: Nutrition Source Type: research

Consumption of whole grain food and its determinants in a general Italian population: results from the INHES Study
ConclusionsThe percentage of WG consumers in Italy in 2010-2013 appears to be quite low and still below that recorded in other countries of Europe where consumption is frequently over 50 percent. WG consumption is likely to be influenced by socioeconomic status and is associated with a number of psychosocial factors, meal patterns and eating-related behaviors. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 13, 2019 Category: Nutrition Source Type: research

Maternal psychological distress during pregnancy and childhood cardio-metabolic risk factors
ConclusionsMaternal psychological distress may influence their offspring heart rate and triglycerides concentrations. Further studies are needed to replicate these findings and assess the long-term cardio-metabolic consequences of maternal psychological distress. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 7, 2019 Category: Nutrition Source Type: research

Early vs. standard screening and treatment of gestational diabetes in high-risk women – An attempt to determine relative advantages and disadvantages
ConclusionEarly vs. standard screening and treatment of GDM in high-risk women is associated with similar short-term maternal-fetal outcomes, although women with an early diagnosis were treated to a greater extent with insulin therapy. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - March 4, 2019 Category: Nutrition Source Type: research

Exposure to solar ultraviolet radiation limits diet-induced weight gain, increases liver triglycerides and prevents the early signs of cardiovascular disease in mice
ConclusionOur results show that the UV contained in sunlight has the potential to prevent and treat chronic disease at sites distant from irradiated skin. A major health challenge going forward will be to harness the power of the sun safely, without risking an increase in skin cancers.Graphical abstract (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - February 28, 2019 Category: Nutrition Source Type: research

Mediterranean, but not lacto-ovo-vegetarian, diet positively influence circulating progenitor cells for cardiovascular prevention: the CARDIVEG study
Publication date: Available online 26 February 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Francesca Cesari, Monica Dinu, Giuditta Pagliai, Angela Rogolino, Betti Giusti, Anna Maria Gori, Alessandro Casini, Rossella Marcucci, Francesco SofiAbstractAimTo evaluate the possible association between dietary habits and progenitor cells using data obtained from a randomized crossover trial using two different diets, lacto-ovo-vegetarian (VD) and Mediterranean (MD), the CARDIVEG study.MethodsEighty clinically healthy subjects with a low-to-moderate cardiovascular risk profile (61 F; 19 M; mean age: 50.7...
Source: Nutrition, Metabolism and Cardiovascular Diseases - February 26, 2019 Category: Nutrition Source Type: research