Relationship between legume consumption and metabolic syndrome: A systematic review and meta-analysis of observational studies
ConclusionLegume consumption is not associated with odds of MetS. These findings require validation in well-designed cohort studies and randomized clinical trials with accurate measurement of legume intake and strict control of confounders.RegistrationThis study was registered with the International Prospective Register of Systematic Reviews (registration number: CRD42019131777). (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 15, 2019 Category: Nutrition Source Type: research

Association Between Dairy Product Consumption and Hyperuricemia in an Elderly Population With Metabolic Syndrome
Publication date: Available online 11 October 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Guillermo Mena-Sánchez, Nancy Babio, Nerea Becerra-Tomás, Miguel Ángel Martínez-González, Andrés Díaz-López, Dolores Corella, Maria Dolores Zomeño, Dora Romaguera, Jesús Vioque, Ángel M. Alonso-Gómez, Julia Wärnberg, J. Alfredo Martínez, Luís Serra-Majem, Ramon Estruch, Rosa Bernal, José Lapetra, Xavier Pintó, Josep A. Tur, José Lopez-Miranda, Naomi Cano-IbáñezAbstractBac...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 12, 2019 Category: Nutrition Source Type: research

The effects of green coffee been extract supplementation on lipid profile in humans: A systematic review and meta-analysis of randomized controlled trials
Publication date: Available online 11 October 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Ding Feng, Baoping Ma, Ali Nazary-Vannani, Hamed Kord-Varkaneh, Somaye Fatahi, Maria Papageorgiou, Jamal Rahmani, Faezeh Poursoleiman, Israel Júnior Borges do Nascimento, Hui Li, Dongyang Ham, Dongmei WangAbstractBackground and aimThis systematic review and meta-analysis aimed to assess the effects of green coffee bean extract (GCBE) supplementation on lipid profile in adults.Methods and resultsThe PubMed/Medline, Scopus, Web of sciences, and Google Scholar were systematically searched for randomized...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 12, 2019 Category: Nutrition Source Type: research

The impact of probiotic yogurt consumption on lipid profiles in subjects with mild to moderate hypercholesterolemia: A systematic review and meta-analysis of randomized controlled trials
ConclusionAvailable evidence suggests that probiotic yogurt can significantly reduce total cholesterol and LDL-c in subjects with mild to moderate hypercholesterolemia without a significant effect on HDL-c and triglyceride levels. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 12, 2019 Category: Nutrition Source Type: research

Metabolic Abnormalities, But Not Obesity Per Se, Associated with Chronic Kidney Disease in a Taiwanese Population
This study enrolled 14983 eligible subjects stratified into metabolically healthy normal weight (MHNW), metabolically healthy overweight (MHOW), metabolically healthy obesity (MHO), metabolically unhealthy normal weight (MUNW), metabolically unhealthy overweight (MUOW), and metabolically unhealthy obesity (MUO) according to body mass index and metabolic syndrome status (ATP-III criteria). The metabolic healthy phenotype was defined as the absence of both metabolic syndrome and any known diabetes, coronary artery disease, stroke, hypertension or dyslipidemia. Early and advanced CKD were defined as eGFR
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 11, 2019 Category: Nutrition Source Type: research

Association of Daily Fish Intake with Serum Non-high-density Lipoprotein Cholesterol Levels and Healthy Lifestyle Behaviours in Apparently Healthy Males over the Age of 50 Years in Japanese: Implication for the Anti-atherosclerotic Effect of Fish Consumption
Publication date: Available online 4 October 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Shigemasa Tani, Rei Matsuo, Kazuhiro Imatake, Yasuyuki Suzuki, Atsuhiko Takahashi, Naoya MatsumotoAbstractBackgroundHigher fish consumption has been reported to be associated with a lower incidence of coronary artery disease (CAD). We hypothesized that higher fish intake may be associated with lower serum level of non-high-density lipoprotein cholesterol (non-HDL-C) levels, representing the entire dyslipidemia spectrum, and a healthy lifestyle.Methods and resultsThis cross-sectional study was conducted in a ...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 5, 2019 Category: Nutrition Source Type: research

Irisin as a Mediator between Obesity and Vascular Inflammation in Chinese Children and Adolescents
ConclusionsOur study showed that Irisin levels change may indicate the early stages of cardiovascular disease in obese children. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 4, 2019 Category: Nutrition Source Type: research

Diabetic kidney disease: New clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on “The natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function”
ConclusionsThe heterogeneity in the clinical presentation and course of DKD has important implications for the diagnosis, prognosis, and possibly treatment of this complication. The therapeutic options for patients with type 2 diabetes and impaired renal function have substantially increased, thus allowing a better management of these individuals. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 4, 2019 Category: Nutrition Source Type: research

MicroRNA-217-5p ameliorates endothelial cell apoptosis induced by ox-LDL by targeting CLIC4
ConclusionWe revealed for the first time that miR-217-5p inhibited apoptosis of endothelial cells in atherosclerosis and identified CLIC4 as a novel target of miR-217-5p. Our work provides a potential therapeutic approach for the treatment of atherosclerosis. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 2, 2019 Category: Nutrition Source Type: research

The Role of Childhood BMI in Predicting Early Adulthood Dysglycemia: Tehran Lipid and Glucose Study
ConclusionThese findings show that overweight or obesity in childhood have no independent role for developing adulthood dysglycemia. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 2, 2019 Category: Nutrition Source Type: research

Moderate and heavy alcohol consumption are prospectively associated with decreased left ventricular ejection fraction: The Hoorn Study
ConclusionThe findings provide longitudinal evidence that moderate and heavy alcohol consumption are associated with decreased LVEF and trend towards a higher risk of incident LV systolic dysfunction, compared to light drinkers. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 2, 2019 Category: Nutrition Source Type: research

Grape seed procyanidin suppresses inflammation in cigarette smoke-exposed pulmonary arterial hypertension rats via PPAR γ/COX-2 pathway
ConclusionThese findings indicate that GSP ameliorates inflammation via PPAR γ/COX-2 pathway and finally inhibits the proliferation of PASMCs, which pulmonary vascular remodeling mainly results from. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 2, 2019 Category: Nutrition Source Type: research

Homocysteine levels and platelet reactivity in coronary artery disease patients treated with Ticagrelor
Publication date: Available online 30 September 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Monica Verdoia, Roberta Rolla, Federica Negro, Francesco Tonon, Patrizia Pergolini, Matteo Nardin, Marco Marcolongo, Giuseppe De Luca, Novara Atherosclerosis Study Group (NAS)AbstractBackgroundRecurrent atherothrombotic events have been reported in certain higher risk subsets of patients even with ticagrelor, a potent first-line antiplatelet agent for the management of patients with acute coronary syndrome (ACS). Hyperhomocysteinemia is a known determinant of platelet function abnormalities. Therefore, th...
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 2, 2019 Category: Nutrition Source Type: research

Dietary patterns and cardiovascular disease in Greek adults: the Hellenic National Nutrition and Health Survey (HNNHS)
ConclusionThe variability of food intake combinations in the Greek population seem to be associated with the presence of CVD and CVD related conditions. Such findings are imperative for national monitoring and informed priority setting. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 2, 2019 Category: Nutrition Source Type: research

Dietary saturated fat intake and risk of stroke: systematic review and dose-response meta-analysis of prospective cohort studies
ConclusionThis meta-analysis further demonstrated that a higher consumption of dietary SFA is associated with a lower risk of stroke, and every 10 grams/day increase in SFA intake is associated with a 6% relative risk reduction in the rate of stroke. Further research is needed to explore the influence of specific SFA types and different macronutrient replacement models of SFA on the stroke risk. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 2, 2019 Category: Nutrition Source Type: research

Letter to the Editor about PNPLA3 gene polymorphism in Brazilian patients with type 2 diabetes: A prognostic marker beyond liver disease?
Publication date: Available online 26 September 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Alessandro Mantovani, Chiara Zusi (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 27, 2019 Category: Nutrition Source Type: research

Lipoprotein(a) levels are associated with coronary severity but not with outcomes in Chinese patients underwent percutaneous coronary intervention
ConclusionLp(a) is an independent predictor of the prevalence of more complex coronary artery lesions (SYNTAX score ≥ 23) in patients with PCI. In addition, our study has shown that Lp(a) has no relationship with long-term cardiovascular outcomes in Chinese patients with PCI. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 27, 2019 Category: Nutrition Source Type: research

Cyclic Glycine-Proline Normalizes Systolic Blood Pressure in High-fat Diet-Induced Obese Male Rats
ConclusionHFD-associated decreases in IGFBP-3 and increases in cGP represent an autocrine response to normalize IGF-1 function through improving the amount of bioavailable IGF-1 in the circulation of obese male rats. The beneficial effects of cGP on SBP and retroperitoneal fat mass may suggest a therapeutic potential for cGP in HFD-associated cardio-metabolic complications.Graphical abstract (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 27, 2019 Category: Nutrition Source Type: research

Excess weight mediates changes in HDL pool that reduce cholesterol efflux capacity and increase antioxidant activity
Publication date: Available online 23 September 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Jose Carlos de Lima-Junior, Vitor W.M. Virginio, Filipe A. Moura, Adriana Bertolami, Marcelo Bertolami, Otavio R. Coelho-Filho, Ilaria Zanotti, Wilson Nadruz, Eliana Cotta de Faria, Luiz Sergio F. de Carvalho, Andrei C. SpositoAbstractBackgroundObesity-related decline in high-density lipoprotein (HDL) functions such as cholesterol efflux capacity (CEC) has supported the notion that this lipoprotein dysfunction may contribute for atherogenesis among obese patients. We investigated if potentially other HDL ...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 24, 2019 Category: Nutrition Source Type: research

Worldwide burden of LDL cholesterol: implications in cardiovascular disease
ConclusionMore effective structural healthcare policies shall be planned at a worldwide scale for contrasting the epidemics of LDL-C attributable heath loss. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 24, 2019 Category: Nutrition Source Type: research

Reply to Drs Mantovani and Zusi
Publication date: Available online 21 September 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Cristiane A. Villela-Nogueira, Nathalie C. Leite, Carolina M. Machado, Claudia R. Cardoso, Gil F. Salles (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 22, 2019 Category: Nutrition Source Type: research

Value of Triglyceride-glucose Index for the Estimation of Ischemic Stroke Risk: Insights from a general Population
Publication date: Available online 21 September 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Wenrui Shi, Liying Xing, Li Jing, Yuanmeng Tian, Han Yan, Qun Sun, Dong Dai, Lei Shi, Shuang LiuAbstractBackground and AimsRecent studies have recognized triglyceride-glucose index (TyG) as a practical surrogate of insulin resistance. Previous studies have demonstrated that insulin resistance contributes to ischemic stroke via multiple mechanisms. Our study aimed to investigate the association between TyG and prevalent ischemic stroke, exploring the value of TyG to optimize the risk stratification of isch...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 22, 2019 Category: Nutrition Source Type: research

Statins therapy and colorectal cancer risk
Publication date: Available online 18 September 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Shih-Wei Lai, Yu-Hung Kuo, Chia-Wei Fang, Kuan-Fu Liao (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 18, 2019 Category: Nutrition Source Type: research

Chronic metformin reduces systemic and local inflammatory proteins and improves hypertension-related cardiac autonomic dysfunction
ConclusionChronic metformin presented anti-inflammatory and antioxidant effects and, independently of alterations in glycaemia, it improved cardiac autonomic parameters that are impaired in hypertension, being related to end-organ damage and mortality. These findings open up perspectives for future innovative uses of metformin in cardiovascular diseases, especially in hypertension.Graphical abstract (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 18, 2019 Category: Nutrition Source Type: research

Exploring the causal pathway from omega-6 levels to coronary heart disease: A network Mendelian randomization study
ConclusionsUsing a network MR framework, we provided evidence supporting a positive causal relationship between omega-6 and CHD, which might be partially mediated by TC, LDL-C, and TG. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 17, 2019 Category: Nutrition Source Type: research

Platelet function and activation markers in primary hypercholesterolemia treated with PCSK9 monoclonal antibody: a 12-month follow-up
ConclusionBesides markedly lowering LDL-c levels, our results suggest that HC patients benefit from PCSK9 mAb treatment also for reducing platelet reactivity and increasing platelet sensitivity to the inhibitory effects of aspirin. These effects on platelets could play a role in the reduction of CV event incidence in patients treated with PCSK9-inhibitors. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 17, 2019 Category: Nutrition Source Type: research

Ameliorative Effects of Hempseed (Cannabis Sativa) Against Hypercholesterolemia Associated Cardiovascular Changes
ConclusionsCurrent study evidently demonstrates that the anti-hypercholesterolemic effects of HS are mediated through redox-sensitive modulation of inflammatory pathways.Graphical abstract (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 14, 2019 Category: Nutrition Source Type: research

Influence of muscle mass on the serum uric acid levels in children and adolescents
ConclusionSexual differences in serum UA levels begin at puberty and partially result from a direct influence of muscle mass. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 13, 2019 Category: Nutrition Source Type: research

Preclinical vascular alterations in obese adolescents detected by Laser-Doppler Flowmetry technique
ConclusionLDF showed very early, pre-clinical, vascular involvement in obese adolescents, characterized by impaired skin microcirculation, possibly reflecting a more diffuse microvascular dysfunction to other body tissues. Whether changing life style and improving weight may reverse such pre-clinical alterations remains to be established. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 13, 2019 Category: Nutrition Source Type: research

Phenotypes and concentration of PON1 in cardiovascular disease: the role of nutrient intake
Publication date: Available online 10 September 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): N. Ponce-Ruiz, F.E. Murillo-González, A.E. Rojas-García, Y.Y. Bernal-Hernández, Mike Mackness, J. Ponce-Gallegos, B.S. Barrón-Vivanco, I. Hernández-Ochoa, C.A. González-Arias, L. Ortega-Cervantes, G. Cardoso-Saldaña, I.M. Medina-DíazAbstractBackground and aimsParaoxonase 1 (PON1) is considered to play a crucial role as an anti-atherosclerotic factor. The PON1 activity is affected by genetic polymorphisms, environmental factors, age, sex, lifestyle, p...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 11, 2019 Category: Nutrition Source Type: research

Serum 25-hydroxyvitamin-D and nonalcoholic fatty liver disease: Does race/ethnicity matter? Findings from the MESA Cohort
Publication date: Available online 10 September 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Samar.R. El Khoudary, Saad Samargandy, Irfan Zeb, Temitope Foster, Ian H. de Boer, Dong Li, Matthew J. BudoffAbstractBackground and AimsLow serum 25-hydroxyvitamin D (25(OH)D) is associated with higher nonalcoholic fatty liver disease (NAFLD) risk in studies of mainly white participants. Significant racial/ethnic differences exist in serum 25(OH)D and NAFLD prevalence questioning extending this association to other racial/ethnic groups. We tested whether the association between serum 25(OH)D and NAFLD var...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 11, 2019 Category: Nutrition Source Type: research

Diabetes Diagnosis from Administrative Claims and Estimation of the True Prevalence of Diabetes among 4.2 Million Individuals of the Veneto Region (North East Italy)
ConclusionWe herein validated an algorithm for the diagnosis of diabetes using administrative claims against the clinical diagnosis. Together with rHIE laboratory data, this allowed to identify possibly undiagnosed diabetes and estimate the true prevalence of diabetes in Veneto. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 10, 2019 Category: Nutrition Source Type: research

Does a rise in plasma erythropoietin after high-altitude exposure affect FGF23 in healthy volunteers on normal or low phosphorus diet?
ConclusionThese data do not support a substantial effect of moderate hypoxia alone upon the expression of FGF23, but they suggest that exercise and high-altitude exposure combined may temporarily induce FGF23 expression. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 10, 2019 Category: Nutrition Source Type: research

Carbohydrate intake and risk of metabolic syndrome: a dose-response meta-analysis from observational studies
ConclusionCarbohydrate intake is associated with an increased risk of developing MetS. Therefore, additional large prospective cohort studies are warranted to confirm our findings. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 10, 2019 Category: Nutrition Source Type: research

Insulin-like growth factor-1 short-period therapy improves cardiomyopathy stimulating cardiac progenitor cells survival in obese mice
ConclusionThese results suggest that only one week of IGF-1therapy has cardioprotective effects through Akt pathway upregulation, ensuring CPC survival and differentiation, contributing to heart failure rescue. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 10, 2019 Category: Nutrition Source Type: research

Osteoprotegerin in diabetic osteopathy
Publication date: Available online 9 September 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Alessia Valentini, Maria Assunta Cianfarani, Massimo Federici, Umberto Tarantino, Aldo BertoliAbstractAimThe aim of this study is to evaluate the relationship between OPG and the degree of glycaemic control in a population of elderly subjects.MethodsData presented included 172 elderly subjects, of whom 107 were hospitalized for a hip fracture and 65 were non fractured outpatients. All participants received a multidimensional geriatric evaluation and underwent blood sampling. HbA1c, OPG, CTX and OC were mea...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 10, 2019 Category: Nutrition Source Type: research

Editorial Board
Publication date: October 2019Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 29, Issue 10Author(s): (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 10, 2019 Category: Nutrition Source Type: research

Relationship between adherence to the Mediterranean Diet, intracerebral hemorrhage, and its location
Publication date: October 2019Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 29, Issue 10Author(s): Antonino Tuttolomondo, Domenico Di Raimondo, Alessandra Casuccio, Mariachiara Velardo, Giovanni Salamone, Valentina Arnao, Rosaria Pecoraro, Vittoriano Della Corte, Vincenzo Restivo, Francesca Corpora, Carlo Maida, Irene Simonetta, Anna Cirrincione, Valerio Vassallo, Antonio PintoAbstractIntroductionAlthough some authors evaluated the relationship between adherence to the Mediterranean Diet (MeDi) and both ischemic and hemorrhagic stroke, hemorrhagic stroke alone is not yet examined.AimsWe conducted a retr...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 10, 2019 Category: Nutrition Source Type: research

The Association of Dietary Patterns and Carotid Intima-Media Thickness: A Synthesis of Current Evidence
ConclusionFindings from this review are generally supportive of a trend between DPs with higher consumption of ‘healthy’ foods and lower consumption of ‘unhealthy’ foods and decreased CIMT; however, the association was largely not statistically significant. Evidence was overwhelmingly heterogeneous due to differences seen in DPs based on location and culture, sample characteristics and adjustment for confounders. Long-term prospective observational and interventional studies with standardized sample selection and dietary data collection are needed to significantly establish the role of DPs on CIMT. ...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 3, 2019 Category: Nutrition Source Type: research

Circulating glutamate level as a potential biomarker for abdominal obesity and metabolic risk
Publication date: Available online 31 August 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): I. Maltais-Payette, B. Allam-Ndoul, L. Pérusse, M.-C. Vohl, A. TchernofAbstractBackground and AimCirculating level of glutamate, a by-product of the catabolism of branched-chain amino acids, has been positively correlated with visceral adipose tissue accumulation and waist circumference (WC). The aim of the present study was to assess the potential of using glutamate level to identify individuals with abdominal obesity and a high cardiometabolic risk.Methods and resultsThe study sample included 99 men...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 1, 2019 Category: Nutrition Source Type: research

Myeloperoxidase as cardiovascular risk marker in pre-pubertal preterm children?
Publication date: Available online 31 August 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): D.O. Schoeps, S. Holzer, F.I.M.D. Suano-Souza, S. Hix, F.L.A. Fonseca, R.O.S. SarniAbstractBackground and AimsTo evaluate the biomarkers related to cardiovascular risk in pre-pubertal preterm children with a birth weight of less than 1,500g and relate them to current nutritional status, insulin resistance, and inflammation.Methods& Results: This is a cross-sectional, controlled study with pre-pubertal preterm children aged 5-9 years with a birth weight of less than 1,500 grams (Preterm group, n=44) compa...
Source: Nutrition, Metabolism and Cardiovascular Diseases - September 1, 2019 Category: Nutrition Source Type: research

Physical Activity Intervention Improved The Number And Functionality Of Endothelial Progenitor Cells In Low Birth Weight Children
ConclusionsA 10-week PA program attenuates the adverse effect of LBW on the number and functionality of EPCs; this effect occurs through an improvement in circulating levels of NO and VEGF-A.Clinical TrialsNCT02982967.Clinical Trialshttps://www.clinicaltrials.gov. Unique Identifier: NCT02982967.Date: December/2016. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 30, 2019 Category: Nutrition Source Type: research

Postnatal delayed growth impacts cognition but rescues programmed impaired pulmonary vascular development in an IUGR rat model
ConclusionThese findings indicate that delayed postnatal growth results in cognitive impairment, but it reverses elevations in mPAP induced by postnatal catch-up growth following IUGR. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 30, 2019 Category: Nutrition Source Type: research

Plaque calcification is driven by different mechanisms of mineralization associated with specific cardiovascular risk factors
ConclusionOur results support the hypothesis that the process of atherosclerotic plaque calcification presents a number of similarities with the physiological processes that occur in bone, involving both osteoblasts- and osteoclasts-like arterial cells. Finally, the present study suggests that risk factors, such as hypertension, cigarette smoke and diabetes, can cause the destabilization of the atheromatic plaque acting on calcification process as well as inflammation. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 24, 2019 Category: Nutrition Source Type: research

Factors associated with longitudinal changes in serum concentrations of Mac-2 binding protein: a prospective 3-year observational study
ConclusionDuring the observation period of>3 years, serum M2BP concentrations were increased in subjects who also exhibited increases in levels of metabolic parameters, especially LDL-C, and the oxidative stress marker d-ROM. These results support that serum M2BP reflects one of the contributors to the progression of silent atherosclerosis.Graphical abstract (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 24, 2019 Category: Nutrition Source Type: research

Associations of a Metabolic Syndrome Severity Score with Coronary Heart Disease and Diabetes in Fasting vs. Non-fasting Individuals
ConclusionsMetS-Z remained linked to future CHD and diabetes when assessed from non-fasting samples. A score such as this may allow for identification of at-risk individuals and serve as a motivation toward interventions to reduce risk. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 24, 2019 Category: Nutrition Source Type: research

Systemic lupus erythematosus is associated with poor outcome after acute myocardial infarction
ConclusionSLE is associated with a higher risk of in-hospital mortality and a borderline significant higher risk of prolonged hospitalization after AMI. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 22, 2019 Category: Nutrition Source Type: research

Validation of the echocardiographic assessment of epicardial adipose tissue thickness at the Rindfleisch fold for the prediction of coronary artery disease
Publication date: Available online 19 August 2019Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Valentina Parisi, Laura Petraglia, Roberto Formisano, Aurelio Caruso, Maria Gabriella Grimaldi, Dario Bruzzese, Fabrizio Vincenzo Grieco, Maddalena Conte, Stefania Paolillo, Alessandra Scatteia, Santo Dellegrottaglie, Annarita Iavazzo, Pasquale Campana, Emanuele Pilato, Patrizio Lancellotti, Vincenzo Russo, Emilio Attena, Pasquale Perrone Filardi, Dario LeoscoAbstractBackgroundEchocardiography is a promising technique for the assessment of epicardial adipose tissue (EAT). Increased EAT thickness is associate...
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 21, 2019 Category: Nutrition Source Type: research

Effect of vitamin D supplementation on endothelial function – an updated systematic review with meta-analysis and meta-regression
ConclusionsVitamin D supplementation showed no improvement in endothelial function. More evidence is required before recommendations for management of endothelial dysfunction can be made. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 21, 2019 Category: Nutrition Source Type: research

The probiotic Lactobacillus fermentum 296 attenuates cardiometabolic disorders in high fat diet-treated rats
ConclusionOur results suggest the ability of L. fermentum 296 improve biochemical and cardiovascular parameters altered in cardiometabolic disorders. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - August 15, 2019 Category: Nutrition Source Type: research