PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

Tumor-to-tumor metastasis to Warthin tumor presenting as an initial sign of breast carcinoma: A case report
Clin Case Rep. 2023 Jan 6;11(1):e6817. doi: 10.1002/ccr3.6817. eCollection 2023 Jan.ABSTRACTMetastases of distant primary tumors on the parotid gland are very rare. Tumor-to-tumor metastasis to salivary gland tumors is extremely rare. A case of a 69-year-old woman with a large left parotid gland mass with no previous salivary gland problems or cancer. Fine-needle aspiration (FNA) showed evidence of a Warthin tumor. A total left parotidectomy was performed. The final pathology report showed a Warthin tumor containing two metastases of adenocarcinoma. The immunohistochemistry of the metastases led to the diagnosis of primary...
Source: Clinical Breast Cancer - January 9, 2023 Category: Cancer & Oncology Authors: Iisa Mansikka Ilpo Kinnunen Jussi Hirvonen Paula Vainio Jarno Velhonoja Source Type: research

Tumor-to-tumor metastasis to Warthin tumor presenting as an initial sign of breast carcinoma: A case report
Clin Case Rep. 2023 Jan 6;11(1):e6817. doi: 10.1002/ccr3.6817. eCollection 2023 Jan.ABSTRACTMetastases of distant primary tumors on the parotid gland are very rare. Tumor-to-tumor metastasis to salivary gland tumors is extremely rare. A case of a 69-year-old woman with a large left parotid gland mass with no previous salivary gland problems or cancer. Fine-needle aspiration (FNA) showed evidence of a Warthin tumor. A total left parotidectomy was performed. The final pathology report showed a Warthin tumor containing two metastases of adenocarcinoma. The immunohistochemistry of the metastases led to the diagnosis of primary...
Source: Clinical Genitourinary Cancer - January 9, 2023 Category: Cancer & Oncology Authors: Iisa Mansikka Ilpo Kinnunen Jussi Hirvonen Paula Vainio Jarno Velhonoja Source Type: research

Tumor-to-tumor metastasis to Warthin tumor presenting as an initial sign of breast carcinoma: A case report
Clin Case Rep. 2023 Jan 6;11(1):e6817. doi: 10.1002/ccr3.6817. eCollection 2023 Jan.ABSTRACTMetastases of distant primary tumors on the parotid gland are very rare. Tumor-to-tumor metastasis to salivary gland tumors is extremely rare. A case of a 69-year-old woman with a large left parotid gland mass with no previous salivary gland problems or cancer. Fine-needle aspiration (FNA) showed evidence of a Warthin tumor. A total left parotidectomy was performed. The final pathology report showed a Warthin tumor containing two metastases of adenocarcinoma. The immunohistochemistry of the metastases led to the diagnosis of primary...
Source: Clinical Breast Cancer - January 9, 2023 Category: Cancer & Oncology Authors: Iisa Mansikka Ilpo Kinnunen Jussi Hirvonen Paula Vainio Jarno Velhonoja Source Type: research

Tumor-to-tumor metastasis to Warthin tumor presenting as an initial sign of breast carcinoma: A case report
Clin Case Rep. 2023 Jan 6;11(1):e6817. doi: 10.1002/ccr3.6817. eCollection 2023 Jan.ABSTRACTMetastases of distant primary tumors on the parotid gland are very rare. Tumor-to-tumor metastasis to salivary gland tumors is extremely rare. A case of a 69-year-old woman with a large left parotid gland mass with no previous salivary gland problems or cancer. Fine-needle aspiration (FNA) showed evidence of a Warthin tumor. A total left parotidectomy was performed. The final pathology report showed a Warthin tumor containing two metastases of adenocarcinoma. The immunohistochemistry of the metastases led to the diagnosis of primary...
Source: Clinical Genitourinary Cancer - January 9, 2023 Category: Cancer & Oncology Authors: Iisa Mansikka Ilpo Kinnunen Jussi Hirvonen Paula Vainio Jarno Velhonoja Source Type: research

Concurrent Warthin tumor and Kimura disease: a case report
ConclusionThis report describes the first concurrent case of WT and KD in the parotid gland. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - January 8, 2023 Category: General Medicine Source Type: research

Tumor ‐to‐tumor metastasis to Warthin tumor presenting as an initial sign of breast carcinoma: A case report
We present a case in which lobular breast carcinoma metastases were found within a Warthin tumor of the left parotid gland. The pathology of the distant metastases steered the diagnostics of the primary breast tumor. This patient case serves as a reminder that a new distant primary cancer might be the cause of a parotid lump. AbstractMetastases of distant primary tumors on the parotid gland are very rare. Tumor-to-tumor metastasis to salivary gland tumors is extremely rare. A case of a 69-year-old woman with a large left parotid gland mass with no previous salivary gland problems or cancer. Fine-needle aspiration (FNA) sho...
Source: Clinical Case Reports - January 7, 2023 Category: General Medicine Authors: Iisa Mansikka, Ilpo Kinnunen, Jussi Hirvonen, Paula Vainio, Jarno Velhonoja Tags: CASE REPORT Source Type: research

Benign tumors of the superficial lobe of the parotid gland
CONCLUSIONS: A comparison between ECD and SP as surgical procedures for the treatment of benign tumors of the parotid seems inappropriate as their indications do not overlap. ECD showed similar effectiveness and fewer side effects than SP and can be considered the treatment of choice for small, superficial and/or marginal tumors located in the lateral lobe of the parotid gland.PMID:36588495 | DOI:10.47162/RJME.63.3.11 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 2, 2023 Category: General Medicine Authors: Eugen Hora ţiu Ştefănescu Carmen Aurelia Mogoant ă Elena Irina C ăluianu Octavian Ion Predescu Charoula Florou Vlad Chercot ă Gheorghe Iov ănescu Source Type: research