CT-based radiomics with various classifiers for histological differentiation of parotid gland tumors
ConclusionOur study demonstrated that noncontrast CT-based radiomics could stratify refined pathological types of parotid tumours well but could not sufficiently differentiate PA from BCA. Different classifiers had the best diagnostic performance for different parotid tumours. Our study findings add to the current knowledge on the differential diagnosis of parotid tumours. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 10, 2023 Category: Cancer & Oncology Source Type: research

Cancers, Vol. 15, Pages 1325: The Value of Multiparametric Magnetic Resonance Imaging in the Preoperative Differential Diagnosis of Parotid Gland Tumors
Conclusions: Morphological analysis using conventional MRI combined with diffusion-weighted imaging (DW) and dynamic contrast–enhanced (DCE) multiparametric MRI improved the preoperative differential diagnosis of parotid gland tumors. (Source: Cancers)
Source: Cancers - February 19, 2023 Category: Cancer & Oncology Authors: Sebastian Stoia Manuela Lenghel Cristian Dinu Tiberiu Tama ș Simion Bran Mihaela B ăciuț Emil Bo țan Daniel Leucu ța Gabriel Armencea Florin Oni șor Grigore B ăciuț Tags: Article Source Type: research

KRAS codon 12 mutations characterize a subset of de novo proliferating “metaplastic” Warthin tumors
AbstractWarthin tumor (WT; synonym: cystadenolymphoma) represents one of the most frequent salivary gland tumors with a frequency equaling or even outnumbering that of pleomorphic adenomas in some series. Histologically, the tumor displays tall columnar oncocytic cells, arranged into two cell-thick layers lining variably cystic glands within an organoid lymphoid stroma. Tumors with exuberant squamous metaplasia in response to FNA-induced or other types of tissue injury/infarction have been referred to as “metaplastic WTs. ” However, the same terminology was used for tumors with variable mucinous cell and solid or strat...
Source: Virchows Archiv - February 8, 2023 Category: Pathology Source Type: research

Locational and Clinical Varieties of Warthin Tumor: Two Rare Case Presentations
Ear Nose Throat J. 2023 Jan 27:1455613221146895. doi: 10.1177/01455613221146895. Online ahead of print.ABSTRACTWarthin tumor (WT) is the second most common benign tumor of the parotid gland with male predominance and is seen in the elderly population in the left mandibular and cervical regions. Extraparotid WT rarely presents as a mass in the right cervical region in middle-aged adults. Here, we present two extraordinary cases of WT seen in middle age, both in the right cervical region. The first is a 50-year-old man with an asymptomatic neck mass, and the second is a 60-year-old woman with a fast-growing mass with enhance...
Source: Ear, Nose and Throat Journal - January 27, 2023 Category: ENT & OMF Authors: Inci S Tascan Ali Yenigun Ferda Ozkan Muzeyyen Dogan Source Type: research

Locational and Clinical Varieties of Warthin Tumor: Two Rare Case Presentations
Ear Nose Throat J. 2023 Jan 27:1455613221146895. doi: 10.1177/01455613221146895. Online ahead of print.ABSTRACTWarthin tumor (WT) is the second most common benign tumor of the parotid gland with male predominance and is seen in the elderly population in the left mandibular and cervical regions. Extraparotid WT rarely presents as a mass in the right cervical region in middle-aged adults. Here, we present two extraordinary cases of WT seen in middle age, both in the right cervical region. The first is a 50-year-old man with an asymptomatic neck mass, and the second is a 60-year-old woman with a fast-growing mass with enhance...
Source: Ear, Nose and Throat Journal - January 27, 2023 Category: ENT & OMF Authors: Inci S Tascan Ali Yenigun Ferda Ozkan Muzeyyen Dogan Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers : Section A of Disease Markers)
Source: Cancer Biomarkers : Section A of Disease Markers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research

PD-L1 expression and CD8 positive lymphocytes in human neoplasms: A tissue microarray study on 11,838 tumor samples
CONCLUSIONS: PD-L1 expression in tumor and inflammatory cells is found in a wide range of human tumor types. Higher rates of tumor infiltrating CD8 positive lymphocytes in PD-L1 positive than in PD-L1 negative cancers suggest that the antitumor immune response may trigger tumoral PD-L1 expression.PMID:36683495 | DOI:10.3233/CBM-220030 (Source: Cancer Biomarkers)
Source: Cancer Biomarkers - January 23, 2023 Category: Cancer & Oncology Authors: Katharina M öller Madeleine Kn öll Elena Bady Max Jonathan Schmerder Sebastian Dwertmann Rico Martina Kluth Claudia Hube-Magg Niclas C Blessin Tim Mandelkow Maximilian Lennartz Anne Menz Andreas M Luebke Doris H öflmayer Christoph Fraune Christian Bern Source Type: research