Concurrent training associated with moderate walnut consumption improved isokinetic strength, subjective sleep quality, cognitive performance and postural balance in elderly active men: a randomized controlled trial
CONCLUSIONS: The present study clearly revealed that concurrent training alone or associated with daily walnut (15 g) consumption for 6 weeks significantly increased knee isokinetic strength, support leg standing parameters and sleep quality. Meanwhile, cognitive performance evaluated by MoCA test and postural balance with dual task were improved for CTW group only.PMID:38421528 | PMC:PMC10904559 | DOI:10.1007/s40520-023-02646-x (Source: Aging Clinical and Experimental Research)
Source: Aging Clinical and Experimental Research - February 29, 2024 Category: Geriatrics Authors: Anis Kamoun Abdelmonem Yahia Mohamed Amine Farjallah Rami Maaloul Houssem Marzougui Mohamed Bouaziz Nizar Souissi Mohamed Habib Elleuch Omar Hammouda Source Type: research

Juglone-ascorbate treatment enhances reactive oxygen species mediated mitochondrial apoptosis in pancreatic cancer
CONCLUSION: Our results suggest that Juglone is a potential anticancer agent especially when combined with ascorbate.PMID:38393422 | DOI:10.1007/s11033-024-09254-6 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - February 23, 2024 Category: Molecular Biology Authors: Dudu Erkoc-Kaya Hilal Arikoglu Ebru Guclu Duygu Dursunoglu Esma Menevse Source Type: research

Juglone-ascorbate treatment enhances reactive oxygen species mediated mitochondrial apoptosis in pancreatic cancer
CONCLUSION: Our results suggest that Juglone is a potential anticancer agent especially when combined with ascorbate.PMID:38393422 | DOI:10.1007/s11033-024-09254-6 (Source: Mol Biol Cell)
Source: Mol Biol Cell - February 23, 2024 Category: Molecular Biology Authors: Dudu Erkoc-Kaya Hilal Arikoglu Ebru Guclu Duygu Dursunoglu Esma Menevse Source Type: research

Juglone-ascorbate treatment enhances reactive oxygen species mediated mitochondrial apoptosis in pancreatic cancer
CONCLUSION: Our results suggest that Juglone is a potential anticancer agent especially when combined with ascorbate.PMID:38393422 | DOI:10.1007/s11033-024-09254-6 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - February 23, 2024 Category: Molecular Biology Authors: Dudu Erkoc-Kaya Hilal Arikoglu Ebru Guclu Duygu Dursunoglu Esma Menevse Source Type: research

Gelatin-based multifunctional composite films integrated with dialdehyde carboxymethyl cellulose and coffee leaf extract for active food packaging
In this study, dialdehyde carboxymethyl cellulose (DCMC, 10 wt% based on gelatin) and varying contents of coffee leaf extract (CLE, 1, 3, 5 and 7 wt% based on gelatin) were incorporated into gelatin (GEL) matrix to develop multifunctional food packaging films. DCMC acted as a physical reinforcing filler through crosslinking with GEL matrix by Schiff-base reaction, CLE served as an active filler to confer film functional properties. The micro-morphology, micro-structure, physicochemical and functional properties of the GEL/DCMC/CLE composite film were investigated. The results demonstrated that mechanical, barrier propertie...
Source: International Journal of Biological Macromolecules - February 21, 2024 Category: Biochemistry Authors: Fangfei Sun Peng Shan Bingzhen Liu Yongshi Li Kun Wang Yongliang Zhuang Delu Ning Hui Li Source Type: research

Integrated metabolomic and transcriptomic dynamic profiles of endopleura coloration during fruit maturation in three walnut cultivars
The color of endopleura is a vital factor in determining the economic value and aesthetics appeal of nut. Walnuts (Juglans) are a key source of edible nuts, high in proteins, amino acids, lipids, carbohydrates. W... (Source: BMC Plant Biology)
Source: BMC Plant Biology - February 14, 2024 Category: Biology Authors: Hengzhao Liu, Huijuan Zhou, Hang Ye, Fangdong Gen, Mengfan Lei, Jinhan Li, Wenjun Wei, Zhanlin Liu, Na Hou and Peng Zhao Tags: Research Source Type: research

Molecules, Vol. 29, Pages 805: & lsquo;Sorrento & rsquo; and & lsquo;Tulare & rsquo; Walnut Cultivars: Morphological Traits and Phytochemical Enhancement of Their Shell Waste
Molecules, Vol. 29, Pages 805: ‘Sorrento’ and ‘Tulare’ Walnut Cultivars: Morphological Traits and Phytochemical Enhancement of Their Shell Waste Molecules doi: 10.3390/molecules29040805 Authors: Elvira Ferrara Danilo Cice Simona Piccolella Assunta Esposito Milena Petriccione Severina Pacifico Walnut processing generates considerable quantities of by-products that could be reprocessed into value-added products that have food and non-food applications. In this context, the aim of this study is to characterize the ‘Sorrento’ and &lsq...
Source: Molecules - February 9, 2024 Category: Chemistry Authors: Elvira Ferrara Danilo Cice Simona Piccolella Assunta Esposito Milena Petriccione Severina Pacifico Tags: Article Source Type: research

IgE Binding and Cross-reactivity to Linear and Conformational Epitopes of Peanut and Walnut Vicilin-buried Peptides
Peanut-allergic individuals can exhibit clinically-relevant IgE cross-reactivity to various tree nuts, particularly walnut. Vicilin-buried peptides (VBPs) found in vicilin leader sequences (LS) are a new class of allergens in peanut and tree nuts that contribute to IgE cross-reactivity. The contribution of the linear and conformational epitopes to cross-reactivity of peanut and walnut VBPs is assessed here. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Lauren Swientoniewski, Ian Rambo, Jacqueline Nesbit, Hsiaopo Cheng, Stephen Gipson, Stacie Jones, Stephen Dreskin, Shahzad Mustafa, Scott Smith, Geoffrey Mueller, Soheila Maleki Source Type: research

Treatment of Single and Multiple Food Allergies with ADP101: Results of the Harmony Phase 1/2 Trial
The phase 1/2 Harmony trial (NCT04856865) evaluated ADP101, a pharmaceutical-grade, investigational multifood oral immunotherapy (mOIT) for simultaneous treatment of allergy to 1-5 foods in ADP101 (almond, cashew, chicken ’s egg, codfish, cow’s milk, hazelnut, peanut, pecan, pistachio, salmon, sesame, shrimp, soy, walnut, wheat). (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Daniel Petroni, Amy Archer, Mei-lun Wang, Lisa Tuomi, Shannon Bradley, Cheri Piscia-Nichols, Ashley Dombkowski, Dana McClintock Source Type: research

Long-term walnut oral immunotherapy induces shifts in serum antibody binding patterns to walnut and cross-reactive tree nuts
To assess the impact of long-term walnut oral immunotherapy (WOIT) on clinical outcomes in relation to changes in IgE and IgG4 binding patterns to walnut (WN) and test tree nut (tTN) allergens among multi-TN allergic study participants. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Dieu Doan, Ian Rambo, Lauren Swientoniewski, Soheila Maleki, Emily Seminara, Amy Scurlock, Stacie Jones Source Type: research

OIT-associated Changes in Gut Metabolites and Potential Effects on Gut Epithelial Integrity
Gut microbiome composition and associated metabolites are implicated in the persistent food allergic (FA) state, contributing to perturbations in gut permeability. Reduced short chain fatty acid (SCFA) stool levels are associated with FA, and Prevotella copri and Bacteroides species contribute to the increased acetate observed in the stool of nonallergic subjects. Our objective was to investigate stool metabolite changes in patients undergoing walnut oral immunotherapy (OIT), and to evaluate their potential effects on gut integrity. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Michael Goldberg, Michael Appel, Nofar Asulin, Ron Schweitzer, Soliman Khatib, Hadar Mor, Liat Nachshon, Sondra Turjeman, Omry Koren, Arnon Elizur Source Type: research

Threshold of Allergic Reactions to Walnut and Pecan in a Large Israeli Population
Information regarding reaction thresholds to walnut and pecan in tree-nuts allergic population is missing. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Liat Nachshon, Michael Goldberg, Michael Levy, Naama Epstein-Rigbi, Arnon Elizur Source Type: research

Interplay of Walnut and Peanut Allergies in Pediatric Anaphylaxis: Prevalence, Cross-Reactivity, and Therapeutic Implications
This study examines its risk in a large food anaphylactic pediatric cohort enrolled in the Tolerance Induction Program (TIPTM). The evolutionary conservation between peanut and walnut proteins and the clinical observations indicating those with peanut allergy are at increased risk for walnut allergy underscores the potential utility of walnuts in advancing biosimilar protein immunotherapy. (Source: Journal of Allergy and Clinical Immunology)
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Diana Fregoso, Inderpal Randhawa, Nathan Marsteller Source Type: research

Food- induced anaphylaxis with initially negative, but subsequently positive IgE sensitization.
A 15-year old patient presented with a recent episode of anaphylaxis after ingesting cashew containing food, accompanied by a strong positive prick test. Our patient had abstained from tree nut- containing foods after experiencing a similar episode 10 years ago after a walnut ingestion, but with negative skin prick and imunoCAP test. This prompted us to conduct a literature review to investigate how minimal or negative sensitization at the onset of the clinical symptoms can be associated with observable clinical reactions, and how sensitization may increase even in the absence of consuming allergen-containing foods. (Sourc...
Source: Journal of Allergy and Clinical Immunology - February 1, 2024 Category: Allergy & Immunology Authors: Charles Song, Andrew Wong, Alexandra Sabo Source Type: research

Molecules, Vol. 29, Pages 498: Walnut By-Products and Elderberry Extracts & mdash;Sustainable Alternatives for Human and Plant Health
Molecules, Vol. 29, Pages 498: Walnut By-Products and Elderberry Extracts—Sustainable Alternatives for Human and Plant Health Molecules doi: 10.3390/molecules29020498 Authors: Anca Sandu-Bălan (Tăbăcariu) Irina-Loredana Ifrim Oana-Irina Patriciu Ioana-Adriana Ștefănescu Adriana-Luminița Fînaru A current alternative for sustainable development through green chemistry is the replacement of synthetic compounds with natural ones through the superior capitalization of natural resources, with numerous applications in different fields. The benefits of walnuts (Juglans regia L.) and elderberries (S...
Source: Molecules - January 19, 2024 Category: Chemistry Authors: Anca Sandu-B ălan (Tăbăcariu) Irina-Loredana Ifrim Oana-Irina Patriciu Ioana-Adriana Ștefănescu Adriana-Lumini ța Fînaru Tags: Review Source Type: research