Gut Microbial Dysbiosis Differs in Two Distinct Cachectic Tumor-Bearing Models Consuming the Same Diet
This study assessed the effect of two cachectic-producing tumor types on the gut microbiota to determine if a similar dysbiosis could be found. In addition, it was determined if a diet containing an immunonutrient-rich food (walnuts) known to promote the growth of probiotic bacteria in the colon could alter the dysbiosis and slow cachexia. Male Fisher 344 rats were randomly assigned to a semi-purified diet with or without walnuts. Then, within each diet group, rats were further assigned randomly to a treatment group: tumor-bearing ad libitum fed (TB), non-tumor-bearing ad libitum fed (NTB-AL), and non-tumor-bearing group p...
Source: Cancer Control - April 13, 2024 Category: Cancer & Oncology Authors: Lauri O Byerley Brittany Lorenzen Hsiao-Man Chang William G Hartman Michael J Keenan Ryan Page Meng Luo Scot E Dowd Christopher M Taylor Source Type: research

Morphological and pomological assessments of seedling-originated walnut (Juglans regia L.) trees to select the promising late-leafing genotypes
In many parts of the world, including Iran, walnut (Juglans regia L.) production is limited by late-spring frosts. Therefore, the use of late-leafing walnuts in areas with late-spring frost is the most important ... (Source: BMC Plant Biology)
Source: BMC Plant Biology - April 8, 2024 Category: Biology Authors: Fariba Einollahi and Ali Khadivi Tags: Research Source Type: research

Molecules, Vol. 29, Pages 1662: Fluorescence Detection of Pb2+ in Environmental Water Using Biomass Carbon Quantum Dots Modified with Acetamide-Glycolic Acid Deep Eutectic Solvent
In this study, a novel green fluorescent probe material, nitrogen-doped carbon quantum dots (N-CQDs), was prepared by a one-step hydrothermal synthesis method using walnut green skin as a carbon source and acetamide-glycolic acid deep eutectic solvent (AGADES) as a modifier. By covalent coupling, the amide chromophore in AGADES is designed to cover the surface of walnut green skin carbon quantum dots (W-CQDs), forming a fluorescence energy resonance effect and improving the fluorescence performance of the carbon quantum dots. The prepared N-CQDs have a uniform particle size distribution, and the fluorescence quantum effici...
Source: Molecules - April 7, 2024 Category: Chemistry Authors: Shiwen Xing Keyang Zheng Lei Shi Kaiming Kang Zhixiao Peng Xiaojie Zhang Baoyou Liu Huilong Yang Gang Yue Tags: Article Source Type: research

A novel angiotensin I-converting enzyme inhibitory peptide from walnut (Juglans sigillata) protein hydrolysates and its evaluation in Ang II-induced HUVECs and hypertensive rats
This study aims to seek angiotensin-I-converting enzyme inhibitory (ACEi) peptides from walnut using different enzymatic hydrolysis, and further to validate the potent ACEi peptides identified and screened via peptidomics and in silico analysis against hypertension in spontaneously hypertensive rats (SHRs). Results showed that walnut protein hydrolysate (WPH) prepared by combination of alcalase and simulated gastrointestinal digestion exhibited high ACEi activity. WPH was separated via Sephadex-G25, and four peptides were identified, screened and verified based on their PeptideRanker score, structural characteristic and AC...
Source: International Journal of Biological Macromolecules - March 31, 2024 Category: Biochemistry Authors: Jinxiang Xie Shupeng Chen Pengtao Huan Shuguang Wang Yongliang Zhuang Source Type: research

A novel angiotensin I-converting enzyme inhibitory peptide from walnut (Juglans sigillata) protein hydrolysates and its evaluation in Ang II-induced HUVECs and hypertensive rats
This study aims to seek angiotensin-I-converting enzyme inhibitory (ACEi) peptides from walnut using different enzymatic hydrolysis, and further to validate the potent ACEi peptides identified and screened via peptidomics and in silico analysis against hypertension in spontaneously hypertensive rats (SHRs). Results showed that walnut protein hydrolysate (WPH) prepared by combination of alcalase and simulated gastrointestinal digestion exhibited high ACEi activity. WPH was separated via Sephadex-G25, and four peptides were identified, screened and verified based on their PeptideRanker score, structural characteristic and AC...
Source: International Journal of Biological Macromolecules - March 31, 2024 Category: Biochemistry Authors: Jinxiang Xie Shupeng Chen Pengtao Huan Shuguang Wang Yongliang Zhuang Source Type: research

Synthesis of an ınnovative SF/NZVI catalyst and ınvestigation of its effectiveness on bio-oil production in liquefaction process alongside other parameters
In this study, walnut shells (WS) were liquefied catalytically and non-catalytically under different parameters using the liquefaction method. In this process, the effect of silica fume/nano zero-valent iron (SF/NZVI) catalysts on the conversion rates was investigated. The catalyst was synthesized by reducing NZVI using a liquid phase chemical reduction method on SF. The SF/NZVI catalyst was characterized by scanning electron microscopy- energy dispersive X-ray (SEM-EDX), transmission electron microscope (TEM), Brunauer-Emmett-Teller (BET), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and X-ray ...
Source: Environmental Science and Pollution Research International - March 25, 2024 Category: Environmental Health Authors: K übra Ersöz Bahar Bayrak Figen G ündüz H üseyin Karaca Source Type: research

Synthesis of an ınnovative SF/NZVI catalyst and ınvestigation of its effectiveness on bio-oil production in liquefaction process alongside other parameters
In this study, walnut shells (WS) were liquefied catalytically and non-catalytically under different parameters using the liquefaction method. In this process, the effect of silica fume/nano zero-valent iron (SF/NZVI) catalysts on the conversion rates was investigated. The catalyst was synthesized by reducing NZVI using a liquid phase chemical reduction method on SF. The SF/NZVI catalyst was characterized by scanning electron microscopy- energy dispersive X-ray (SEM-EDX), transmission electron microscope (TEM), Brunauer-Emmett-Teller (BET), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and X-ray ...
Source: Environmental Science and Pollution Research International - March 25, 2024 Category: Environmental Health Authors: K übra Ersöz Bahar Bayrak Figen G ündüz H üseyin Karaca Source Type: research

Development and characterization of nuclear microsatellite markers for the African walnut Coula edulis Baill (Coulaceae)
CONCLUSIONS: The high polymorphism of the nuclear microsatellite markers developed makes them useful to investigate gene flow and the organization of genetic diversity in C. edulis, and to assess whether particular genetic resources require conservation efforts.PMID:38520482 | DOI:10.1007/s11033-024-09373-0 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 23, 2024 Category: Molecular Biology Authors: Narcisse Guy Kamdem Saskia Sergeant Camille Vercruysse Vincent Deblauwe Bonaventure Sonk é Olivier J Hardy Source Type: research

Development and characterization of nuclear microsatellite markers for the African walnut Coula edulis Baill (Coulaceae)
CONCLUSIONS: The high polymorphism of the nuclear microsatellite markers developed makes them useful to investigate gene flow and the organization of genetic diversity in C. edulis, and to assess whether particular genetic resources require conservation efforts.PMID:38520482 | DOI:10.1007/s11033-024-09373-0 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 23, 2024 Category: Molecular Biology Authors: Narcisse Guy Kamdem Saskia Sergeant Camille Vercruysse Vincent Deblauwe Bonaventure Sonk é Olivier J Hardy Source Type: research

Development and characterization of nuclear microsatellite markers for the African walnut Coula edulis Baill (Coulaceae)
CONCLUSIONS: The high polymorphism of the nuclear microsatellite markers developed makes them useful to investigate gene flow and the organization of genetic diversity in C. edulis, and to assess whether particular genetic resources require conservation efforts.PMID:38520482 | DOI:10.1007/s11033-024-09373-0 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 23, 2024 Category: Molecular Biology Authors: Narcisse Guy Kamdem Saskia Sergeant Camille Vercruysse Vincent Deblauwe Bonaventure Sonk é Olivier J Hardy Source Type: research

Development and characterization of nuclear microsatellite markers for the African walnut Coula edulis Baill (Coulaceae)
CONCLUSIONS: The high polymorphism of the nuclear microsatellite markers developed makes them useful to investigate gene flow and the organization of genetic diversity in C. edulis, and to assess whether particular genetic resources require conservation efforts.PMID:38520482 | DOI:10.1007/s11033-024-09373-0 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - March 23, 2024 Category: Molecular Biology Authors: Narcisse Guy Kamdem Saskia Sergeant Camille Vercruysse Vincent Deblauwe Bonaventure Sonk é Olivier J Hardy Source Type: research

Genome-wide identification analysis of the 4-Coumarate: CoA ligase (4CL) gene family expression profiles in Juglans regia and its wild relatives J. Mandshurica resistance and salt stress
Persian walnut (Juglans regia) and Manchurian walnut (Juglans mandshurica) belong to Juglandaceae, which are vulnerable, temperate deciduous perennial trees with high economical, ecological, and industrial values... (Source: BMC Plant Biology)
Source: BMC Plant Biology - March 23, 2024 Category: Biology Authors: Jiayu Ma, Dongjun Zuo, Xuedong Zhang, Haochen Li, Hang Ye, Nijing Zhang, Mengdi Li, Meng Dang, Fangdong Geng, Huijuan Zhou and Peng Zhao Tags: Research Source Type: research

Complete genome sequence of a novel alternavirus isolated from the phytopathogenic fungus Colletotrichum fioriniae
AbstractA novel double-strand RNA (dsRNA) mycovirus, named “Colletotrichum fioriniae alternavirus1” (CfAV1), was isolated from the strain CX7 ofColletotrichum fioriniae, the causal agent of walnut anthracnose. The complete genome of CfAV1 is composed of three dsRNA segments: dsRNA1 (3528 bp), dsRNA2 (2485 bp), and dsRNA3 (2481 bp). The RNA-dependent RNA polymerase (RdRp) is encoded by dsRNA1, while both dsRNA2 and dsRNA3 encode hypothetical proteins. Based on multiple sequence alignments and phylogenetic analysis, CfAV1 is identified as a new member of the familyAlternaviridae. This is the first report of an alternavir...
Source: Archives of Virology - March 22, 2024 Category: Virology Source Type: research

Establishment of virus-induced gene-silencing system in Juglans sigillata Dode and functional analysis of JsFLS2 and JsFLS4
This study showed that photobleaching occurred 24 and 30 d after the silencing vector was infected with aseptic seedlings and fruits of J. sigillata, respectively. When the OD600 was 0.6, and the injection dose was 500 μL, the gene silencing efficiency of aseptic seedlings was the highest at 16.7 %, significantly better than other treatments. Moreover, when the OD600 was 0.8, and the injection dose was 500 μL, the gene silencing efficiency in the walnut fruit was the highest (20 %). In addition, the VIGS system was successfully used to silence JsFLS2 and JsFLS4 genes in J. sigillata. This study also showed that the flavo...
Source: Gene - March 17, 2024 Category: Genetics & Stem Cells Authors: Yanyang Hong Rong Wei Chunxiang Li Hu Cai Erjuan Chen Xuejun Pan Wen'e Zhang Source Type: research

Establishment of virus-induced gene-silencing system in Juglans sigillata Dode and functional analysis of JsFLS2 and JsFLS4
This study showed that photobleaching occurred 24 and 30 d after the silencing vector was infected with aseptic seedlings and fruits of J. sigillata, respectively. When the OD600 was 0.6, and the injection dose was 500 μL, the gene silencing efficiency of aseptic seedlings was the highest at 16.7 %, significantly better than other treatments. Moreover, when the OD600 was 0.8, and the injection dose was 500 μL, the gene silencing efficiency in the walnut fruit was the highest (20 %). In addition, the VIGS system was successfully used to silence JsFLS2 and JsFLS4 genes in J. sigillata. This study also showed that the flavo...
Source: Gene - March 17, 2024 Category: Genetics & Stem Cells Authors: Yanyang Hong Rong Wei Chunxiang Li Hu Cai Erjuan Chen Xuejun Pan Wen'e Zhang Source Type: research