Aflatoxins and Ochratoxin A in dried fruits from Morocco: Monitoring, regulatory aspects, and exposure assessment
Regul Toxicol Pharmacol. 2023 Sep 29:105503. doi: 10.1016/j.yrtph.2023.105503. Online ahead of print.ABSTRACTThe present study aims to investigate the presence of Aflatoxins (AF) in 180 samples dried fruits and Ochratoxin A (OTA) in 210 samples dried fruits and grape juices collected in Morocco. Mycotoxins were analyzed by high performance liquid chromatography (HPLC) coupled to fluorescence detection and immunoaffinity columns (IAC) cleanup. Contamination levels were compared with the maximum regulatory limits (MRL) recently adopted in the country, and mycotoxin exposure of adult consumers was assessed. Results showed tha...
Source: Regulatory Toxicology and Pharmacology : RTP - October 1, 2023 Category: Toxicology Authors: Nysrine Mannani Mounir El Boujamaai Aicha Sifou Mohamed Bennani Chakib El Adlouni El Hassane Abdennebi Abdellah Zinedine Source Type: research

Aflatoxins and Ochratoxin A in dried fruits from Morocco: Monitoring, regulatory aspects, and exposure assessment
Regul Toxicol Pharmacol. 2023 Sep 29:105503. doi: 10.1016/j.yrtph.2023.105503. Online ahead of print.ABSTRACTThe present study aims to investigate the presence of Aflatoxins (AF) in 180 samples dried fruits and Ochratoxin A (OTA) in 210 samples dried fruits and grape juices collected in Morocco. Mycotoxins were analyzed by high performance liquid chromatography (HPLC) coupled to fluorescence detection and immunoaffinity columns (IAC) cleanup. Contamination levels were compared with the maximum regulatory limits (MRL) recently adopted in the country, and mycotoxin exposure of adult consumers was assessed. Results showed tha...
Source: Regulatory Toxicology and Pharmacology : RTP - October 1, 2023 Category: Toxicology Authors: Nysrine Mannani Mounir El Boujamaai Aicha Sifou Mohamed Bennani Chakib El Adlouni El Hassane Abdennebi Abdellah Zinedine Source Type: research

Aflatoxins and Ochratoxin A in dried fruits from Morocco: Monitoring, regulatory aspects, and exposure assessment
Regul Toxicol Pharmacol. 2023 Sep 29:105503. doi: 10.1016/j.yrtph.2023.105503. Online ahead of print.ABSTRACTThe present study aims to investigate the presence of Aflatoxins (AF) in 180 samples dried fruits and Ochratoxin A (OTA) in 210 samples dried fruits and grape juices collected in Morocco. Mycotoxins were analyzed by high performance liquid chromatography (HPLC) coupled to fluorescence detection and immunoaffinity columns (IAC) cleanup. Contamination levels were compared with the maximum regulatory limits (MRL) recently adopted in the country, and mycotoxin exposure of adult consumers was assessed. Results showed tha...
Source: Regulatory Toxicology and Pharmacology : RTP - October 1, 2023 Category: Toxicology Authors: Nysrine Mannani Mounir El Boujamaai Aicha Sifou Mohamed Bennani Chakib El Adlouni El Hassane Abdennebi Abdellah Zinedine Source Type: research

Aflatoxins and Ochratoxin A in dried fruits from Morocco: Monitoring, regulatory aspects, and exposure assessment
Regul Toxicol Pharmacol. 2023 Sep 29:105503. doi: 10.1016/j.yrtph.2023.105503. Online ahead of print.ABSTRACTThe present study aims to investigate the presence of Aflatoxins (AF) in 180 samples dried fruits and Ochratoxin A (OTA) in 210 samples dried fruits and grape juices collected in Morocco. Mycotoxins were analyzed by high performance liquid chromatography (HPLC) coupled to fluorescence detection and immunoaffinity columns (IAC) cleanup. Contamination levels were compared with the maximum regulatory limits (MRL) recently adopted in the country, and mycotoxin exposure of adult consumers was assessed. Results showed tha...
Source: Regulatory Toxicology and Pharmacology : RTP - October 1, 2023 Category: Toxicology Authors: Nysrine Mannani Mounir El Boujamaai Aicha Sifou Mohamed Bennani Chakib El Adlouni El Hassane Abdennebi Abdellah Zinedine Source Type: research

Analysis of key genes for the survival of Pantoea agglomerans under nutritional stress
Int J Biol Macromol. 2023 Sep 26:127059. doi: 10.1016/j.ijbiomac.2023.127059. Online ahead of print.ABSTRACTThe absolute amount of nutrients on plant leaves is usually low, and the growth of epiphytic bacteria is typically limited by nutrient content. Thus, is of great significance to study the survival mechanism of epiphytes under nutritional stress for plant disease control. In this paper, Pantoea agglomerans CHTF15 isolated from walnut leaves was used to detect the key genes for the survival of the bacterium under simulated nutrient stress in artificial medium. Genome sequencing was combined with transposon insertion se...
Source: International Journal of Biological Macromolecules - September 28, 2023 Category: Biochemistry Authors: Jiawen Xiao Shangyi Sun Zhaosha Liu Chenxi Fan Baocheng Zhu Dongdong Zhang Source Type: research

Analysis of key genes for the survival of Pantoea agglomerans under nutritional stress
Int J Biol Macromol. 2023 Sep 26:127059. doi: 10.1016/j.ijbiomac.2023.127059. Online ahead of print.ABSTRACTThe absolute amount of nutrients on plant leaves is usually low, and the growth of epiphytic bacteria is typically limited by nutrient content. Thus, is of great significance to study the survival mechanism of epiphytes under nutritional stress for plant disease control. In this paper, Pantoea agglomerans CHTF15 isolated from walnut leaves was used to detect the key genes for the survival of the bacterium under simulated nutrient stress in artificial medium. Genome sequencing was combined with transposon insertion se...
Source: International Journal of Biological Macromolecules - September 28, 2023 Category: Biochemistry Authors: Jiawen Xiao Shangyi Sun Zhaosha Liu Chenxi Fan Baocheng Zhu Dongdong Zhang Source Type: research

Comparative evaluation of nutrient composition, in vitro nutritional value, and antioxidant activity of de-oiled meals from walnut, hazelnut, almond, and sesame
This study aimed to establish a comparative database on the chemical composition, in vitro nutritional value, and antioxidant activity of the de-oiled meals produced from walnut, hazelnut, almond, and sesame seeds from the ruminant nutrition perspective. The meals were provided in dried form after their oil harvest using the cold-pressing oil extraction method. Crude protein (CP) constituted the major component of the meals and was the greatest in walnut and almond (average of 45.6% of dry matter (DM)], intermediate in hazelnut meal (41.4%), and least in sesame meal (33.3%)). Potassium was the most abundant mineral in waln...
Source: Tropical Animal Health and Production - September 28, 2023 Category: Veterinary Research Source Type: research

Walnut Consumption and Gut Microbial Metabolism: Results of an Exploratory Analysis from a Randomized, Crossover, Controlled-Feeding Study
The effect of walnut-related modulation of gut microbiota composition on microbiota functionality is unknown. The aim was to characterize the effect of a walnut-enriched diet (WD), compared to a fatty acid-matched diet devoid of walnuts (WFMD) and a diet where oleic acid replaces alpha-linolenic acid (ORAD), on bacterial gene expression. (Source: Clinical Nutrition)
Source: Clinical Nutrition - September 27, 2023 Category: Nutrition Authors: Kristina S. Petersen, Mansi Chandra, Jeremy R. Chen See, Jillian Leister, Fatemeh Jafari, Alyssa Tindall, Penny M. Kris-Etherton, Regina Lamendella Tags: Randomized Control Trials Source Type: research

How gallic acid regulates molecular signaling: role in cancer drug resistance
AbstractCancer is one of the deadliest and most heterogeneous diseases. Cancers often develop drug resistance, which can lead to treatment failure or recurrence. Accordingly, anticancer compounds are essential for chemotherapy-resistant cancer cells. Phenolic compounds are of interest in the development of cancer drugs due to their medicinal properties and ability to target different molecular pathways. Gallic acid (GA), as one of the main components of phenol, which is abundantly present in plant compounds such as walnut, sumac, grapes, tea leaves, oak bark, and other plant compounds, has antitumor properties. GA can prev...
Source: Medical Oncology - September 27, 2023 Category: Cancer & Oncology Source Type: research

Absorption and Metabolism of Urolithin A and Ellagic Acid in Mice and Their Cytotoxicity in Human Colorectal Cancer Cells
Evid Based Complement Alternat Med. 2023 Sep 5;2023:8264716. doi: 10.1155/2023/8264716. eCollection 2023.ABSTRACTBACKGROUND: Ellagic acid is a natural polyphenol compound found in pomegranates, walnuts, and many berries. It is not easily absorbed, but it could be metabolized to urolithins by the gut microbiota. Urolithin A, one of the ellagic acid metabolites, has been proved to prolong the lifespan of C. elegans and increases muscle function of mice. The purpose of this current study was to analyze the absorption and metabolites of urolithin A and ellagic acid in mice and the anticancer effects of urolithin A, urolithin B...
Source: Evidence-based Complementary and Alternative Medicine - September 14, 2023 Category: Complementary Medicine Authors: I-Chen Lin Jin-Yi Wu Chuan-Yin Fang Shou-Chie Wang Yi-Wen Liu Shang-Tse Ho Source Type: research

Genetic imprints of grafting in wild iron walnut populations in southwestern China
Anthropogenic activities are causing unprecedented loss of genetic diversity in many species. However, the effects on genetic diversity from large-scale grafting onto wild plants of crop species are largely un... (Source: BMC Plant Biology)
Source: BMC Plant Biology - September 13, 2023 Category: Biology Authors: Jie Liu, Ephie A. Magige, Peng-Zhen Fan, Moses C. Wambulwa, Ya-Huang Luo, Hai-Ling Qi, Lian-Ming Gao and Richard I. Milne Tags: Research Source Type: research