Differentiated vulvar intraepithelial neoplasia long ‐term follow up and prognostic factors: An analysis of a large historical cohort
ConclusionsPatients with dVIN have a high risk of developing both primary and recurring VSCC. Early recognition, long-term follow up, and compliant ultrapotent topical corticosteroid treatment are recommended. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - February 22, 2024 Category: OBGYN Authors: Niccol ò Gallio,
Mario Preti,
Ronald W. Jones,
Fulvio Borella,
Linn Woelber,
Luca Bertero,
Sara Urru,
Leonardo Micheletti,
Federica Zamagni,
Federica Bevilacqua,
Pierluigi Tondo,
Benedetta Pollano,
Paola Cassoni,
Chiara Benedetto Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Exploring the potential prompting role of cervical human papilloma virus detection in vulvar lesions: a cross-sectional study in China
ConclusionsChinese women may be at specific, high risk for HPV infection types associated with VIN or CIN. The use of cervical cell HPV detection along with vulvar presentation during cervical cancer screening may also contribute to vulvar lesion detection. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - February 15, 2024 Category: Cancer & Oncology Source Type: research
High concordance of molecular subtyping between pre-surgical biopsy and surgical resection specimen (matched-pair analysis) in patients with vulvar squamous cell carcinoma using p16- and p53-immunostaining
CONCLUSIONS: Compared to the final resections specimen, the three-tiered molecular classification of VSCC can be determined on pre-surgical biopsies with a high accuracy rate. This enables more precise surgical planning, prediction of the response to (chemo) radiation, selection of targeted therapies and planning of the optimal follow-up strategy for patients in the age of personalised medicine.PMID:38342005 | DOI:10.1016/j.ygyno.2024.02.001 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - February 11, 2024 Category: Cancer & Oncology Authors: Anne Kathrin H öhn Mirjam Forberger Mona Alfaraidi C Blake Gilks Christine Elisabeth Brambs Michael H öckel Lynn Hoang Naveena Singh Lars-Christian Horn Source Type: research
High concordance of molecular subtyping between pre-surgical biopsy and surgical resection specimen (matched-pair analysis) in patients with vulvar squamous cell carcinoma using p16- and p53-immunostaining
CONCLUSIONS: Compared to the final resections specimen, the three-tiered molecular classification of VSCC can be determined on pre-surgical biopsies with a high accuracy rate. This enables more precise surgical planning, prediction of the response to (chemo) radiation, selection of targeted therapies and planning of the optimal follow-up strategy for patients in the age of personalised medicine.PMID:38342005 | DOI:10.1016/j.ygyno.2024.02.001 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - February 11, 2024 Category: Cancer & Oncology Authors: Anne Kathrin H öhn Mirjam Forberger Mona Alfaraidi C Blake Gilks Christine Elisabeth Brambs Michael H öckel Lynn Hoang Naveena Singh Lars-Christian Horn Source Type: research
Investigation of vulvar biopsy results in patients with vulvar clinical complaints
In this study we aim to compare clinical, demographic and pathologic results of patients who presented in our clinic with vulvar complaints. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - February 1, 2024 Category: OBGYN Authors: Elif Goknur Topcu, Zihniye Gonca Okumus Source Type: research
Accuracy of ICG compared with technetium-99 m for sentinel lymph node biopsy in vulvar cancer
CONCLUSION(S): ICG shows comparable performance parameters to the gold-standard of radioisotope localization.PMID:38183845 | DOI:10.1016/j.ejogrb.2023.12.037 (Source: Reproductive Biology)
Source: Reproductive Biology - January 6, 2024 Category: Reproduction Medicine Authors: Alberto Rafael Guijarro-Campillo Pablo Padilla-Iserte B árbara Couso Diego Erasun Jes ús Utrilla-Layna Octavio Arencibia Ana Boldo-Roda Juan Gilabert-Estell és Nadia Veiga V íctor Lago Jos é Miguel Cárdenas-Rebollo Santiago Domingo Source Type: research
Accuracy of ICG compared with technetium-99 m for sentinel lymph node biopsy in vulvar cancer
Surgery is the primary treatment for early-stage vulvar cancer, including radical local excision with groin evaluation [1,2]. Vulvar cancer guidelines recommend inguinal sentinel lymph node biopsy (SLN) as a standard-of-care in patients with squamous unifocal tumors (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 2, 2024 Category: OBGYN Authors: Alberto Rafael Guijarro-Campillo, Pablo Padilla-Iserte, B árbara Couso, Diego Erasun, Jesús Utrilla-Layna, Octavio Arencibia, Ana Boldo-Roda, Juan Gilabert-Estellés, Nadia Veiga, Víctor Lago, José Miguel Cárdenas-Rebollo, Santiago Domingo Tags: Full length article Source Type: research
Accuracy of ICG compared with technetium-99m for sentinel lymph node biopsy in vulvar cancer
Surgery is the primary treatment for early-stage vulvar cancer, including radical local excision with groin evaluation [1,2]. Vulvar cancer guidelines recommend inguinal sentinel lymph node biopsy (SLN) as a standard-of-care in patients with squamous unifocal tumors (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - January 2, 2024 Category: OBGYN Authors: Alberto Rafael Guijarro-Campillo, Pablo Padilla-Iserte, B árbara Couso, Diego Erasun, Jesús Utrilla-Layna, Octavio Arencibia, Ana Boldo-Roda, Juan Gilabert-Estellés, Nadia Veiga, Víctor Lago, José Miguel Cárdenas-Rebollo, Santiago Domingo Tags: Full length article Source Type: research
A large sample-based case-control study of related risk factors of two types of lichenoid vulvar disease (LVD)
CONCLUSION: The incidence about lichenoid vulvar disease is influenced by various factors such as dietary habits, living environment, mental stress, concomitant diseases, hormone levels and so on, and there were no significant differences in these factors between VLS and VLSC except for income, work stress, systemic immune diseases, and menopause.PMID:38100936 | DOI:10.1016/j.ejogrb.2023.12.002 (Source: Reproductive Biology)
Source: Reproductive Biology - December 15, 2023 Category: Reproduction Medicine Authors: Dongmei Wei Can Luo Yueyue Chen Jijie Li Xiaoyu Niu Source Type: research
A large sample-based case-control study of related risk factors of two types of lichenoid vulvar disease (LVD)
CONCLUSION: The incidence about lichenoid vulvar disease is influenced by various factors such as dietary habits, living environment, mental stress, concomitant diseases, hormone levels and so on, and there were no significant differences in these factors between VLS and VLSC except for income, work stress, systemic immune diseases, and menopause.PMID:38100936 | DOI:10.1016/j.ejogrb.2023.12.002 (Source: Reproductive Biology)
Source: Reproductive Biology - December 15, 2023 Category: Reproduction Medicine Authors: Dongmei Wei Can Luo Yueyue Chen Jijie Li Xiaoyu Niu Source Type: research
CO2 laser, radiofrequency, and promestriene in the treatment of genitourinary syndrome of menopause in breast cancer survivors: a histomorphometric evaluation of the vulvar vestibule
CONCLUSIONS: Laser, radiofrequency, and promestriene delivered comparable, significant symptom improvements among women with breast cancer receiving adjuvant therapy. These treatments did not cause structural tissue damage or other clinical complications.PMID:37963315 | DOI:10.1097/GME.0000000000002274 (Source: Cancer Control)
Source: Cancer Control - November 14, 2023 Category: Cancer & Oncology Authors: Marcela Furtado Roberto Fernandes Ana Maria Homem de Mello Bianchi-Ferraro Marair Gracio Ferreira Sartori Zsuzsanna Ilona Katalin de J ármy Di Bella Gabriela Cruz Cantarelli Chayanne Dedonatto Rafaela Brambatti Vanzin Rita de Cassia Maio Dardes Ângela F Source Type: research
Recurrence of Metastatic Crohn's Disease after Surgical Resection
Skinmed. 2023 Nov 10;21(5):366-369. eCollection 2023.ABSTRACTA 36-year-old woman presented to the emergency department with a 1-day history of purulent perianal and vulvar discharge. She had a 25-year history of Crohn's disease (CD), and 13 years prior had received a total colectomy with end ileostomy. She had vulvar biopsies 5 years prior to presentation, demonstrating noncaseating granulomas consistent with metastatic Crohn's disease (MCD). Throughout the course of her disease, she had a failed treatment with adalimumab, certolizumab, methotrexate, and 6-mercaptopurine. She had received a radical vulvectomy 1 year prior ...
Source: Skinmed - November 9, 2023 Category: Dermatology Authors: Alexander Sherban Matthew Keller Source Type: research
Recurrence of Metastatic Crohn's Disease after Surgical Resection
Skinmed. 2023 Nov 10;21(5):366-369. eCollection 2023.ABSTRACTA 36-year-old woman presented to the emergency department with a 1-day history of purulent perianal and vulvar discharge. She had a 25-year history of Crohn's disease (CD), and 13 years prior had received a total colectomy with end ileostomy. She had vulvar biopsies 5 years prior to presentation, demonstrating noncaseating granulomas consistent with metastatic Crohn's disease (MCD). Throughout the course of her disease, she had a failed treatment with adalimumab, certolizumab, methotrexate, and 6-mercaptopurine. She had received a radical vulvectomy 1 year prior ...
Source: Skinmed - November 9, 2023 Category: Dermatology Authors: Alexander Sherban Matthew Keller Source Type: research
Recurrence of Metastatic Crohn's Disease after Surgical Resection
Skinmed. 2023 Nov 10;21(5):366-369. eCollection 2023.ABSTRACTA 36-year-old woman presented to the emergency department with a 1-day history of purulent perianal and vulvar discharge. She had a 25-year history of Crohn's disease (CD), and 13 years prior had received a total colectomy with end ileostomy. She had vulvar biopsies 5 years prior to presentation, demonstrating noncaseating granulomas consistent with metastatic Crohn's disease (MCD). Throughout the course of her disease, she had a failed treatment with adalimumab, certolizumab, methotrexate, and 6-mercaptopurine. She had received a radical vulvectomy 1 year prior ...
Source: Skinmed - November 9, 2023 Category: Dermatology Authors: Alexander Sherban Matthew Keller Source Type: research
