HBNET: A blended ensemble model for the detection of cardiovascular anomalies using phonocardiogram
CONCLUSION: The results indicate that the HbNet model exhibits a high level of efficacy in the early detection of cardiac disorders. Results also imply that HbNet has the potential to serve as a valuable tool for the development of decision-support systems that aid medical practitioners in confirming their diagnoses. This method makes it easier for medical professionals to diagnose and initiate prompt treatment while performing preliminary auscultation and reduces unnecessary echocardiograms.PMID:38393859 | DOI:10.3233/THC-231290 (Source: Technology and Health Care)
Source: Technology and Health Care - February 23, 2024 Category: Medical Devices Authors: Ann Nita Netto Lizy Abraham Saji Philip Source Type: research
HBNET: A blended ensemble model for the detection of cardiovascular anomalies using phonocardiogram
CONCLUSION: The results indicate that the HbNet model exhibits a high level of efficacy in the early detection of cardiac disorders. Results also imply that HbNet has the potential to serve as a valuable tool for the development of decision-support systems that aid medical practitioners in confirming their diagnoses. This method makes it easier for medical professionals to diagnose and initiate prompt treatment while performing preliminary auscultation and reduces unnecessary echocardiograms.PMID:38393859 | DOI:10.3233/THC-231290 (Source: Technology and Health Care)
Source: Technology and Health Care - February 23, 2024 Category: Medical Devices Authors: Ann Nita Netto Lizy Abraham Saji Philip Source Type: research
Percutaneous pulmonary valve implantation in a patient with congenitally corrected transposition of the great arteries: a case report
ConclusionThis is likely the first description of a percutaneous pulmonary valve implantation in such anatomy. Such a procedure is feasible; however, it requires  exceptional caution owing to the anomalous coronary arteries course, which can be the reason for their compression. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - February 21, 2024 Category: General Medicine Source Type: research
Right-sided aortic arch with isolation of the left innominate artery and hypoplasia of the left internal carotid artery
ConclusionThe right-sided aortic arch, with the isolation of the left innominate artery, is a scarce vascular variation that may occur with other cardiovascular anomalies such as ventricular septal defect. It can be asymptomatic or can present with symptoms of subclavian steal syndrome. Although its association with the agenesis of the left internal carotid artery has been reported, its association with the hypoplasia of the left internal carotid artery has not been reported previously to the best of our knowledge. (Source: Surgical and Radiologic Anatomy)
Source: Surgical and Radiologic Anatomy - February 20, 2024 Category: Anatomy Source Type: research
Congenital lobar emphysema: A diagnostic dilemma with coexistent congenital heart defects
Key Clinical MessageClinicians should think beyond pneumonia and left-to-right shunts when young children have persistent respiratory distress. Congenital lung anomalies, including congenital lobar emphysema, should be considered differential diagnoses. Chest X-ray and CT imaging should be conducted to gain insight regarding and establish diagnosis, respectively.AbstractCongenital lobar emphysema (CLE) is a rare and life-threatening congenital lung anomaly that often poses a diagnostic dilemma. The issue can be further confused with coexistent congenital heart defects (CHDs) with left-to-right shunts. The clinical presenta...
Source: Clinical Case Reports - February 16, 2024 Category: General Medicine Authors: Jigar Prabhulal Thacker,
Vishal Vinayak Bhende,
Tanishq Shashikant Sharma Tags: CASE REPORT Source Type: research
Descending aorta to right atrial fistula: Transcatheter embolization of a very rare anomaly with coils
We present a case report of a trisomy 21 infant with atrial and ventricular septal defects and small patent ductus arteriosus (PDA) complicated by the presence of descending aorta to right atrial (RA) fistula with large left to right shunt leading to rapid increase in pulmonary vascular resistance. Transcatheter occlusion of the fistula followed by closure of the PDA with Nit-Occlud coil systems led to decreased pulmonary pressure and resistance permitting successful surgical repair of the patient's intracardiac defects with good outcome over 3  years of follow-up. Descending aorta to RA fistula is a rare and distinct cl...
Source: Clinical Case Reports - February 14, 2024 Category: General Medicine Authors: Stefanos Despotopoulos,
Sotiria Apostolopoulou,
George Vagenakis,
Meletios Kanakis,
George Samanidis,
Panagiotis Zachos,
Anastasios Chatziantoniou,
John Papagiannis,
Spyridon Rammos,
Alexandros Tsoutsinos Tags: CASE REPORT Source Type: research
Risk Factors of Long-Term Sequelae After Transcatheter Closure of Perimembranous Ventricular Septal Defect in Young Children
CONCLUSIONS: Careful attention is crucial for pmVSDs ≥4.5 mm to prevent persistent residual shunts in transcatheter closure. Assessing AR risk, particularly in children aged <4 years, is essential while considering the benefits of pmVSD closure.PMID:38325819 | DOI:10.1253/circj.CJ-23-0891 (Source: Circulation Journal)
Source: Circulation Journal - February 7, 2024 Category: Cardiology Authors: Chia-Yi Chin Chun-An Chen Chun-Min Fu Jui-Yu Hsu Hsin-Chia Lin Shuenn-Nan Chiu Ya-Mei Chang Chun-Wei Lu Heng-Wen Chou Shu-Chien Huang Yih-Sharng Chen Mei-Hwan Wu Jou-Kou Wang Ming-Tai Lin Source Type: research
Genes, Vol. 15, Pages 207: A Pilot Study of Multiplex Ligation-Dependent Probe Amplification Evaluation of Copy Number Variations in Romanian Children with Congenital Heart Defects
ihaela Mihu
Congenital heart defects (CHDs) have had an increasing prevalence over the last decades, being one of the most common congenital defects. Their etiopathogenesis is multifactorial in origin. About 10&ndash;15% of all CHD can be attributed to copy number variations (CNVs), a type of submicroscopic structural genetic alterations. The aim of this study was to evaluate the involvement of CNVs in the development of congenital heart defects. We performed a cohort study investigating the presence of CNVs in the 22q11.2 region and GATA4, TBX5, NKX2-5, BMP4, and CRELD1 genes in patients with syndromic and iso...
Source: Genes - February 5, 2024 Category: Genetics & Stem Cells Authors: Alexandru Cristian Bolundu ț Florina Nazarie Cecilia Lazea Crina Șufană Diana Miclea C ălin Lazăr Carmen Mihaela Mihu Tags: Article Source Type: research
Maternal Gestational Diabetes Mellitus and Congenital Heart Disease
in Offspring: A Meta-Analysis
Horm Metab Res DOI: 10.1055/a-2238-1710Maternal diabetes has been related to an increased risk of congenital heart
disease (CHD) in offspring. However, inconsistent results were retrieved for
studies evaluating the association between gestational diabetes mellitus (GDM)
and CHD in offspring. We therefore performed a systematic review and
meta-analysis for comprehensive investigation. Observational studies were
identified by searching PubMed, Embase, and Web of Science according to the aim
of the meta-analysis. A randomized-effects model was used to pool the data b...
Source: Hormone and Metabolic Research - February 2, 2024 Category: Endocrinology Authors: Liu, Yun Yue, Lina Chang, Li Tags: Original Article: Endocrine Care Source Type: research
Procedural Efficiencies and Clinical Outcomes for Transcatheter Device Closure of Perimembranous Ventricular Septal Defects With Different Waist-Length Occluders
CONCLUSIONS: Transcatheter closure of pmVSD using a symmetrical double-disk occluder is safe and effective. Compared with a 3-mm waist symmetrical occluder, transcatheter closure with a 4-mm waist symmetrical occluder correlated with higher incidences of residual shunts.PMID:38296536 | DOI:10.1253/circj.CJ-23-0583 (Source: Circulation Journal)
Source: Circulation Journal - January 31, 2024 Category: Cardiology Authors: Diandong Jiang Yuxin Zhang Yingchun Yi Lijian Zhao Jianli Lv Jing Wang Yan Wang Xiaofei Yang Jianjun Zhang Bo Han Source Type: research
Ventricular Septal Defect as a Complication of Bipolar Radiofrequency Ablation for Ventricular Tachycardia
Radiofrequency catheter ablation of ventricular arrhythmias may be unsuccessful if the thermal destruction of myocardial tissue does not reach the critical part of the reentrant circuit. In the case of deep intramural or intraseptal ventricular arrhythmias, adjunctive ablative approaches for deeper lesions may be employed, including bipolar ablation, intracoronary vessel alcohol injection, ablation with hypotonic irrigant such as half-normal saline, and stereotactic body radiation.1 –4 Bipolar ablation, which involves using a second ablation catheter rather than a dispersive patch electrode, focuses current between the c...
Source: Heart Rhythm - January 31, 2024 Category: Cardiology Authors: Timothy R. Maher, Adnan Raza, Carlos Tapias, Fermin Garcia, Matthew R. Reynolds, Ghulam M. Chaudhry, Luis C. Saenz, Miguel Valderr ábano, Andre d’Avila Source Type: research
Volume Alone Does Not Predict Quality Outcomes in Hospitals Performing Pediatric Cardiac Surgery
CONCLUSIONS: This national, real-world, risk-adjusted volume outcome analysis highlights that volume alone may not be the sole arbiter to predict quality of pediatric cardiac surgery outcomes. Using case volume alone as a surrogate for quality may unfairly asperse high-performing, low-volume programs.PMID:38290594 | DOI:10.1016/j.athoracsur.2024.01.006 (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - January 30, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Dhaval Chauhan J Hunter Mehaffey J W Awori Hayanga Jai P Udassi Vinay Badhwar Christopher E Mascio Source Type: research
Intracardiac Three-Dimensional Image as Surgical Decision-Making Tool of Congenital Heart Disease
This study aimed to evaluate the anatomical reproducibility of a preoperative intracardiac 3D image (IC image) created using computed tomography, and to investigate its usefulness as a surgical decision-making tool. Between 2012 and 2022, ventricular septal defect (VSD) patients, and double outlet right ventricle (DORV) or transposition of the great arteries (TGA) with pulmonary stenosis (PS) patients who underwent cardiac surgery and had preoperative computed tomography were enrolled. SYNAPSE VINCENT ® (Fujifilm) was used to create an IC image which was analyzed retrospectively. In 14 VSD patients, the diagnostic consist...
Source: Mammalian Genome - January 28, 2024 Category: Genetics & Stem Cells Source Type: research
A Retrospective Study in Occluding Sub-arterial Ventricular Septal Defect
AbstractTo assess the safety and effectiveness of utilizing eccentric occlusion for the treatment of sub-arterial ventricular septal defects, we performed a retrospective study on the classification and analysis of relevant cases. A total of 105 patients with a minimally invasive incision were enrolled in this study, from April 2018 to September 2022. All patients underwent treatment of transthoracic sub-arterial ventricular septal defect occlusion. We analyzed the causes of closure failure, indication, and complication. Briefly, the closure device was successfully implanted in 78 cases (74.2%) with a mean age of 31.4  Â...
Source: Mammalian Genome - January 28, 2024 Category: Genetics & Stem Cells Source Type: research
Intracardiac Three-Dimensional Image as Surgical Decision-Making Tool of Congenital Heart Disease
This study aimed to evaluate the anatomical reproducibility of a preoperative intracardiac 3D image (IC image) created using computed tomography, and to investigate its usefulness as a surgical decision-making tool. Between 2012 and 2022, ventricular septal defect (VSD) patients, and double outlet right ventricle (DORV) or transposition of the great arteries (TGA) with pulmonary stenosis (PS) patients who underwent cardiac surgery and had preoperative computed tomography were enrolled. SYNAPSE VINCENT ® (Fujifilm) was used to create an IC image which was analyzed retrospectively. In 14 VSD patients, the diagnostic consist...
Source: Pediatric Cardiology - January 27, 2024 Category: Cardiology Source Type: research
