A Retrospective Study in Occluding Sub-arterial Ventricular Septal Defect
AbstractTo assess the safety and effectiveness of utilizing eccentric occlusion for the treatment of sub-arterial ventricular septal defects, we performed a retrospective study on the classification and analysis of relevant cases. A total of 105 patients with a minimally invasive incision were enrolled in this study, from April 2018 to September 2022. All patients underwent treatment of transthoracic sub-arterial ventricular septal defect occlusion. We analyzed the causes of closure failure, indication, and complication. Briefly, the closure device was successfully implanted in 78 cases (74.2%) with a mean age of 31.4  Â...
Source: Pediatric Cardiology - January 27, 2024 Category: Cardiology Source Type: research

Hemodynamic simulation of complete transposition of the great arteries for optimal treatment strategies based on its circulatory physiology
Am J Physiol Heart Circ Physiol. 2024 Jan 26. doi: 10.1152/ajpheart.00668.2023. Online ahead of print.ABSTRACTOur study aimed to elucidate the role of different shunts and provide novel insights into optimal treatment approaches for complete transposition of the great arteries (TGA), which is characterized by unique and complicated circulatory dynamics. We constructed a computational cardiovascular TGA model and manipulated cardiovascular parameters, such as atrial septal defect (ASD) and patent ductus arteriosus (PDA) sizes, to quantify their effects on oxygenation and hemodynamics. Additionally, ASD flow patterns were in...
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 26, 2024 Category: Physiology Authors: Kaname Sato Koichi Takamizawa Yosuke Ogawa Yu Tanaka Kazuhiro Shiraga Hitomi Masuda Hikoro Matsui Ryo Inuzuka Hideaki Senzaki Source Type: research

Usefulness of perioperative transoesophageal echocardiography during paediatric cardiac surgery
CONCLUSION: Perioperative transoesophageal echocardiography is a safe procedure, providing information on severe residual lesions, leading to the immediate revision of several paediatric congenital heart disease cases.PMID:38272760 | DOI:10.1016/j.acvd.2023.12.006 (Source: Archives of Cardiovascular Diseases)
Source: Archives of Cardiovascular Diseases - January 25, 2024 Category: Cardiology Authors: Pierrick Pyra Khaled Hadeed Aitor Guitarte Vidaurre R émi Vincent Yves Dulac G érald Chausseray Davide Felice Calvaruso Philippe Acar Cl ément Karsenty Source Type: research

Communication interventriculaire compliquant un infarctus de myocarde ant érieur : un cas de fermeture percutanée
CONCLUSION: Percutaneous closure has been emerged as a valid cost-effective alternative to surgery and should be advised. However, debate remains on the optimal preprocedural optimization, timing of repair and modality of treatment.PMID:38262253 | DOI:10.1016/j.ancard.2023.101718 (Source: Annales de Cardiologie et d'Angeiologie)
Source: Annales de Cardiologie et d'Angeiologie - January 23, 2024 Category: Cardiology Authors: Hakim Lamine Abdeljelil Farhati Hela Bouzidi Syrine Saidane Ihsen Zairi Khadija Mzoughi Sondos Kraeim Source Type: research

En Bloc Rotation of the Outflow Tracts – Double Root Translocation
En bloc rotation of the outflow tracts or double root translocation offers an anatomic repair of transposition of the great arteries, ventricular septal defect, and left ventricular outflow tract obstruction and closely related forms of double outlet right ventricle. The technical principle is to excise aortic and pulmonary root en bloc, rotate them as a whole by 180 °, and reimplant them. The left ventricular outflow tract is enlarged with the patch closing the ventricular septal defect. In our experience, two thirds of the pulmonary valves could be preserved (8,9, 15). (Source: Seminars in Thoracic and Cardiovascular Su...
Source: Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual - January 23, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Rudolf Mair, Michaela Kreuzer, Eva Sames-Dolzer Source Type: research

Early Clinical Outcomes in Infants with Prenatally Diagnosed Perimembranous and Muscular Ventricular Septal Defects (VSDs)
AbstractIsolated ventricular septal defect (VSD) is often associated with good clinical outcomes. However, infants prenatally diagnosed with VSD are often recommended for delivery at tertiary care centers. The aim of our study was to determine the odds of neonatal intensive care unit (NICU) admission in infants with persistent isolated VSD and complicated VSD, where an infant is affected by VSD and other genetic/structural abnormalities. We performed a retrospective cohort study, with data collected from a single academic institution from June 2018 to March 2023. Individuals with prenatally diagnosed VSD, in the absence of...
Source: Mammalian Genome - January 20, 2024 Category: Genetics & Stem Cells Source Type: research

Early Clinical Outcomes in Infants with Prenatally Diagnosed Perimembranous and Muscular Ventricular Septal Defects (VSDs)
AbstractIsolated ventricular septal defect (VSD) is often associated with good clinical outcomes. However, infants prenatally diagnosed with VSD are often recommended for delivery at tertiary care centers. The aim of our study was to determine the odds of neonatal intensive care unit (NICU) admission in infants with persistent isolated VSD and complicated VSD, where an infant is affected by VSD and other genetic/structural abnormalities. We performed a retrospective cohort study, with data collected from a single academic institution from June 2018 to March 2023. Individuals with prenatally diagnosed VSD, in the absence of...
Source: Pediatric Cardiology - January 20, 2024 Category: Cardiology Source Type: research

Establishing a High-Quality Pediatric Cardiac Surgery Program in Post-Conflict Regions: A Model for Limited Resource Countries
ConclusionThe partnership model between a local public entity committed to infrastructure development and funding and an international private organization delivering clinical and training services can provide the foundation for building sustainable, high-quality in situ programs in upper-middle-income countries. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - January 19, 2024 Category: Cardiology Source Type: research

Left Ventricular Dysfunction Following Repair of Ventricular Septal Defects in Infants
AbstractLeft ventricular systolic dysfunction (LVSD) is frequently observed following repair of ventricular septal defects (VSD), although little is known about its incidence, time course, or risk factors. Among infants undergoing VSD repair, for postoperative LVSD, we sought to determine (1) incidence, (2) predictors, and (3) time to resolution. We queried our institution ’s surgical database for infants who underwent repair of isolated VSDs from November 2001 through January 2019. The primary outcome was postoperative LVSD, which was defined as a shortening fraction (SF) of<26% by M-mode. Postoperative echocardiogra...
Source: Pediatric Cardiology - January 18, 2024 Category: Cardiology Source Type: research

Left Ventricular Dysfunction Following Repair of Ventricular Septal Defects in Infants
AbstractLeft ventricular systolic dysfunction (LVSD) is frequently observed following repair of ventricular septal defects (VSD), although little is known about its incidence, time course, or risk factors. Among infants undergoing VSD repair, for postoperative LVSD, we sought to determine (1) incidence, (2) predictors, and (3) time to resolution. We queried our institution ’s surgical database for infants who underwent repair of isolated VSDs from November 2001 through January 2019. The primary outcome was postoperative LVSD, which was defined as a shortening fraction (SF) of<26% by M-mode. Postoperative echocardiogra...
Source: Mammalian Genome - January 18, 2024 Category: Genetics & Stem Cells Source Type: research

Hemodynamics in Adults with Systemic Right Ventricles: Differences Between Congenitally Corrected and Complete Transposition of the Great Arteries
In conclusion , despite sharing a sRV, adults with d-TGA and ccTGA have substantial differences in hemodynamics and structural/valvular abnormalities. Further investigation regarding disease-specific responses to heart failure therapy in those with d-TGA and ccTGA is warranted. (Source: Pediatric Cardiology)
Source: Pediatric Cardiology - January 17, 2024 Category: Cardiology Source Type: research

Hemodynamics in Adults with Systemic Right Ventricles: Differences Between Congenitally Corrected and Complete Transposition of the Great Arteries
In conclusion , despite sharing a sRV, adults with d-TGA and ccTGA have substantial differences in hemodynamics and structural/valvular abnormalities. Further investigation regarding disease-specific responses to heart failure therapy in those with d-TGA and ccTGA is warranted. (Source: Mammalian Genome)
Source: Mammalian Genome - January 17, 2024 Category: Genetics & Stem Cells Source Type: research

Upper partial sternal split for pediatric cardiac surgery
ConclusionAn upper partial sternal split approach is straightforward and can be performed safely with a preferable cosmetic result in selected pediatric cardiac operations. (Source: General Thoracic and Cardiovascular Surgery)
Source: General Thoracic and Cardiovascular Surgery - January 16, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research

Revolutionizing cardiovascular care: the power of histotripsy
AbstractHistotripsy, an innovative ultrasonic technique, is poised to transform the landscape of cardiovascular disease management. This review explores the multifaceted applications of histotripsy across various domains of cardiovascular medicine. In thrombolysis, histotripsy presents a non-invasive, drug-free, and precise method for recanalizing blood vessels obstructed by clots, minimizing the risk of vessel damage and embolism. Additionally, histotripsy showcases its potential in congenital heart defect management, offering a promising alternative to invasive procedures by creating intracardiac communications noninvasi...
Source: Journal of Ultrasound - January 13, 2024 Category: Radiology Source Type: research