Keeping It "Current": A Review of Treatment Options for the Management of Supraventricular Tachycardia
CONCLUSIONS: With high annual rates of ED visits for SVT, providers should be aware of the data behind management and modifications of therapy based on patient-specific factors (ie, patient preference, pharmacokinetics/pharmacodynamics, drug interactions, and special populations).PMID:37743672 | DOI:10.1177/10600280231199136 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - September 25, 2023 Category: Drugs & Pharmacology Authors: Patrick Tednes Samantha Marquardt Shannon Kuhrau Kristin Heagler Megan Rech Source Type: research
Keeping It "Current": A Review of Treatment Options for the Management of Supraventricular Tachycardia
CONCLUSIONS: With high annual rates of ED visits for SVT, providers should be aware of the data behind management and modifications of therapy based on patient-specific factors (ie, patient preference, pharmacokinetics/pharmacodynamics, drug interactions, and special populations).PMID:37743672 | DOI:10.1177/10600280231199136 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - September 25, 2023 Category: Drugs & Pharmacology Authors: Patrick Tednes Samantha Marquardt Shannon Kuhrau Kristin Heagler Megan Rech Source Type: research
Impact of amiodarone use on metoprolol concentrations, α‐OH‐metoprolol concentrations, metoprolol dosing and heart rate: A cross‐sectional study
AbstractSmall studies suggest that amiodarone is a weak inhibitor of cytochrome P450 (CYP) 2D6. Inhibition of CYP2D6 leads to increases in concentrations of drugs metabolized by the enzyme, such as metoprolol. Considering that both metoprolol and amiodarone have β-adrenergic blocking properties and that the modest interaction between the two drugs would result in increased metoprolol concentrations, this could lead to a higher risk of bradycardia and atrioventricular block. The primary objective of this study was to evaluate whether metoprolol plasma conce ntrations collected at random timepoints from patients enrolled in...
Source: Pharmacology Research and Perspectives - September 22, 2023 Category: Drugs & Pharmacology Authors: Sabrina Robert,
Marc ‐Olivier Pilon,
Essaïd Oussaïd,
Maxime Meloche,
Grégoire Leclair,
Martin Jutras,
Marie‐Josée Gaulin,
Ian Mongrain,
David Busseuil,
Jean‐Claude Tardif,
Marie‐Pierre Dubé,
Simon Denus Tags: SHORT REPORT Source Type: research
Effects of ivabradine on ventricular electrophysiological remodeling after myocardial infarction in rats
CONCLUSIONS: IVA can reduce the incidence of ventricular arrhythmia after MI in male rats by improving both structural and electrical remodeling, and the combination of IVA and MET is even more effective.PMID:37732052 | PMC:PMC10507765 | DOI:10.5114/aoms.2020.101181 (Source: Archives of Medical Science)
Source: Archives of Medical Science - September 21, 2023 Category: Biomedical Science Authors: Li-Ping Jiang Jing-Jing Lin Ting-Pei Zhuang Wei-Wei Wang Hang-Zhou Wu Fei-Long Zhang Source Type: research
Transient left bundle branch block associated with very high coronary artery calcium: a case report
We present a case of very high CAC in a 64-year-old woman with hypertension, type 2 diabetes, and hyperlipidemia presenting with dyspnea. Initial electrocardiogram (ECG) demonstrated normal conduction with a heart rate of 76 beats/min, but new T-wave inversions in V1-V4 and a high-sensitivity troponin-I (hsTnI) value of 6 ng/L (normal < 6 ng/L). Repeat ECG in the emergency department showed normal sinus rhythm (heart rate of 80 beats/min); however, it subsequently demonstrated a left bundle branch block (LBBB) with a repeat hsTnI of 7 ng/L. Stress testing with pharmacologic single-photon emission computerized tomography...
Source: Atherosclerosis - September 19, 2023 Category: Cardiology Authors: Alexander C Razavi Sindhu Prabakaran Mariem Sawan Lakshmi Tummala Ifeoma Onuorah Sagar B Amin Marly van Assen Carlo N De Cecco Arshed A Quyyumi Seamus P Whelton Laurence S Sperling Francois G Rollin Source Type: research
Transient left bundle branch block associated with very high coronary artery calcium: a case report
We present a case of very high CAC in a 64-year-old woman with hypertension, type 2 diabetes, and hyperlipidemia presenting with dyspnea. Initial electrocardiogram (ECG) demonstrated normal conduction with a heart rate of 76 beats/min, but new T-wave inversions in V1-V4 and a high-sensitivity troponin-I (hsTnI) value of 6 ng/L (normal < 6 ng/L). Repeat ECG in the emergency department showed normal sinus rhythm (heart rate of 80 beats/min); however, it subsequently demonstrated a left bundle branch block (LBBB) with a repeat hsTnI of 7 ng/L. Stress testing with pharmacologic single-photon emission computerized tomography...
Source: Atherosclerosis - September 19, 2023 Category: Cardiology Authors: Alexander C Razavi Sindhu Prabakaran Mariem Sawan Lakshmi Tummala Ifeoma Onuorah Sagar B Amin Marly van Assen Carlo N De Cecco Arshed A Quyyumi Seamus P Whelton Laurence S Sperling Francois G Rollin Source Type: research
Hypertrophic obstructive cardiomyopathy caused by Fabry disease: implications for surgical myectomy
This study emphasizes the importance of a genetic screening for FD before SSM be considered for hypertrophic obstructive cardiomyopathy. (Source: ESC Heart Failure)
Source: ESC Heart Failure - September 16, 2023 Category: Cardiology Authors: Andrea Frustaci,
Valentino Borghetti,
Samuele Pentiricci,
Romina Verardo,
Rossella Scialla,
Matteo Antonio Russo Tags: Case Report Source Type: research
Impact of Concomitant Cardiovascular Therapies on Efficacy and Safety of Relugolix vs Leuprolide: Subgroup Analysis from HERO Study in Advanced Prostate Cancer
CONCLUSION: Relugolix suppressed testosterone and was generally well tolerated when given with concomitant CV agents.TRIAL REGISTRATION: Clinical Trial ID NCT03085095.PRIOR PRESENTATION: Data presented at 15th Annual Genitourinary Cancers Symposium; February 17-19, 2022, San Francisco, CA, USA [Abstract 101, Poster board E11]. The published abstract from this presentation can be found at https://ascopubs.org/doi/10.1200/JCO.2022.40.6_suppl.101 .PMID:37713020 | DOI:10.1007/s12325-023-02634-7 (Source: Adv Data)
Source: Adv Data - September 15, 2023 Category: Epidemiology Authors: Neal D Shore Bryan A Mehlhaff Michael S Cookson Daniel R Saltzstein Ronald Tutrone Bruce Brown Sophia Lu Mark Fallick Sarah Hanson Fred Saad Source Type: research
