Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Mol Biol Cell - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Mol Biol Cell - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
Comparison of the Protective Effects of Nebivolol and Metoprolol against LPS-Induced Injury in H9c2 Cardiomyoblasts
Curr Issues Mol Biol. 2023 Nov 20;45(11):9316-9327. doi: 10.3390/cimb45110583.ABSTRACTHere, we, for the first time, compared the cardioprotective effects of third-generation vasodilating beta-blocker nebivolol (Neb) and conventional beta-blocker metoprolol (Met) on LPS-induced injury in H9c2 cardiomyoblasts. Our findings denoted that Neb and Met pretreatment diminish LPS-mediated cytotoxicity and oxidative stress. Concomitantly, LPS-triggered inflammatory cytokines activation was significantly suppressed by Neb but not by Met. Pretreatment with either Neb or Met alleviated LPS-mediated mitochondrial impairment by enhancing...
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Rukhsana Gul Meshail Okla Amer Mahmood Shahid Nawaz Amina Fallata Arwa Bazighifan Musaad Alfayez Assim A Alfadda Source Type: research
