Clinical Pathology Conference: Case 4: An exophytic gingival mass of the right anterior mandible
An 83-year-old male presented to a community oral maxillofacial surgeon with a tender, pink, pedunculated exophytic tumor measuring 2 × 1.5 cm involving the right anterior mandible adjacent to tooth #27 (Figure 1A). His medical history was significant for hypertension, congestive heart failure, atrial fibrillation, and prostate cancer treated with radiation and androgen deprivation chemotherapy. The patient had been taking a miodarone, metoprolol, digoxin, rivaroxaban, furosemide, bicalutamide, and leuprorelin injections. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - April 24, 2024 Category: ENT & OMF Authors: Safia Durab, Ida A. Varghese, Laith Mahmood, Nadarajah Vigneswaran Source Type: research
Study on genotype and phenotype of novel CYP2D6 variants using pharmacokinetic and pharmacodynamic models with metoprolol as a substrate drug
The Pharmacogenomics Journal, Published online: 18 April 2024; doi:10.1038/s41397-024-00332-3Study on genotype and phenotype of novel CYP2D6 variants using pharmacokinetic and pharmacodynamic models with metoprolol as a substrate drug (Source: The Pharmacogenomics Journal)
Source: The Pharmacogenomics Journal - April 18, 2024 Category: Drugs & Pharmacology Authors: Jianchang Qian Tao Xu Peipei Pan Wei Sun Guoxin Hu Jianping Cai Source Type: research
Anaerobic co-metabolic biodegradation of pharmaceuticals and personal care products driven by glycerol fermentation
This study showed evidence that glycerol co-fermentation can exert a synergistic effect on the PPCPs removal during anaerobic digestion mediated by heterotrophic co-metabolism.PMID:38621493 | DOI:10.1016/j.chemosphere.2024.142006 (Source: Chemosphere)
Source: Chemosphere - April 15, 2024 Category: Chemistry Authors: Rodrigo B Carneiro Gisele M Gomes Franciele P Camargo Marcelo Zaiat Álvaro J Santos-Neto Source Type: research
Anaerobic co-metabolic biodegradation of pharmaceuticals and personal care products driven by glycerol fermentation
This study showed evidence that glycerol co-fermentation can exert a synergistic effect on the PPCPs removal during anaerobic digestion mediated by heterotrophic co-metabolism.PMID:38621493 | DOI:10.1016/j.chemosphere.2024.142006 (Source: Chemosphere)
Source: Chemosphere - April 15, 2024 Category: Chemistry Authors: Rodrigo B Carneiro Gisele M Gomes Franciele P Camargo Marcelo Zaiat Álvaro J Santos-Neto Source Type: research
Serious Bleeding in Patients With Atrial Fibrillation Using Diltiazem With Apixaban or Rivaroxaban
This cohort study assesses the association of diltiazem with risk of serious bleeding compared with metoprolol in older adults with atrial fibrillation receiving apixaban or rivaroxaban. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 15, 2024 Category: General Medicine Source Type: research
Age and mean platelet volume-based nomogram for predicting the therapeutic efficacy of metoprolol in Chinese pediatric patients with vasovagal syncope
CONCLUSION: A novel nomogram based on age and MPV can predict the therapeutic benefits of metoprolol in children with VVS.PMID:38613734 | DOI:10.1007/s12519-024-00802-5 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - April 13, 2024 Category: Pediatrics Authors: Xiao-Juan Du Ya-Qian Huang Xue-Ying Li Ying Liao Hong-Fang Jin Jun-Bao Du Source Type: research
Age and mean platelet volume-based nomogram for predicting the therapeutic efficacy of metoprolol in Chinese pediatric patients with vasovagal syncope
CONCLUSION: A novel nomogram based on age and MPV can predict the therapeutic benefits of metoprolol in children with VVS.PMID:38613734 | DOI:10.1007/s12519-024-00802-5 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - April 13, 2024 Category: Pediatrics Authors: Xiao-Juan Du Ya-Qian Huang Xue-Ying Li Ying Liao Hong-Fang Jin Jun-Bao Du Source Type: research
Age and mean platelet volume-based nomogram for predicting the therapeutic efficacy of metoprolol in Chinese pediatric patients with vasovagal syncope
CONCLUSION: A novel nomogram based on age and MPV can predict the therapeutic benefits of metoprolol in children with VVS.PMID:38613734 | DOI:10.1007/s12519-024-00802-5 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - April 13, 2024 Category: Pediatrics Authors: Xiao-Juan Du Ya-Qian Huang Xue-Ying Li Ying Liao Hong-Fang Jin Jun-Bao Du Source Type: research
Age and mean platelet volume-based nomogram for predicting the therapeutic efficacy of metoprolol in Chinese pediatric patients with vasovagal syncope
CONCLUSION: A novel nomogram based on age and MPV can predict the therapeutic benefits of metoprolol in children with VVS.PMID:38613734 | DOI:10.1007/s12519-024-00802-5 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - April 13, 2024 Category: Pediatrics Authors: Xiao-Juan Du Ya-Qian Huang Xue-Ying Li Ying Liao Hong-Fang Jin Jun-Bao Du Source Type: research
Age and mean platelet volume-based nomogram for predicting the therapeutic efficacy of metoprolol in Chinese pediatric patients with vasovagal syncope
CONCLUSION: A novel nomogram based on age and MPV can predict the therapeutic benefits of metoprolol in children with VVS.PMID:38613734 | DOI:10.1007/s12519-024-00802-5 (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - April 13, 2024 Category: Pediatrics Authors: Xiao-Juan Du Ya-Qian Huang Xue-Ying Li Ying Liao Hong-Fang Jin Jun-Bao Du Source Type: research
Beta-blocking patients with cardiac amyloidosis: Adelante cum juicio
Once upon a time, beta-blockers (BB) were simply forbidden for the treatment of patients with heart failure (HF): they were thought to worsen clinical severity of the disease, eliciting salt/water retention, reducing myocardial contractility, impairing hemodynamics. [1] Therefore, although the first evidence of metoprolol efficacy was given in 1975, only 20 years after, in 1993, the first randomized study paved the way to a widespread use, finally guideline-recommended since 1999 up to 2021. [2] In the meanwhile, Packer's neurohormonal model of HF overcame the cardiocirculatory and cardiorenal ones. (Source: Internation...
Source: International Journal of Cardiology - April 12, 2024 Category: Cardiology Authors: Michele Emdin, Alberto Aimo, Giuseppe Vergaro, Vincenzo Castiglione Source Type: research
Application of non-lethal bioSPME-LC-MS/MS for the detection of human pharmaceuticals in soft corals: A survey at the North Nilandhe atoll (Maldives)
Chemosphere. 2024 Mar 28:141781. doi: 10.1016/j.chemosphere.2024.141781. Online ahead of print.ABSTRACTAt present the information regarding the occurrence of human pharmaceuticals (PhaCs) in coral reefs and their potential impacts on the associated fauna is limited. To optimize the collection of data in these delicate environments, we employed a solid-phase microextraction (bioSPME) and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) procedure that enabled in vivo determinations in soft corals. Specifically, we researched the antibiotics Ofloxacin Sulfamethoxazole and Clarithromycin, the anti-inflammat...
Source: Chemosphere - March 30, 2024 Category: Chemistry Authors: Alessandro Becchi Marco Mantovani Marina Lasagni Elena Collina Simone Montano Paolo Galli Francesco Saliu Source Type: research
Application of non-lethal bioSPME-LC-MS/MS for the detection of human pharmaceuticals in soft corals: A survey at the North Nilandhe atoll (Maldives)
Chemosphere. 2024 Mar 28:141781. doi: 10.1016/j.chemosphere.2024.141781. Online ahead of print.ABSTRACTAt present the information regarding the occurrence of human pharmaceuticals (PhaCs) in coral reefs and their potential impacts on the associated fauna is limited. To optimize the collection of data in these delicate environments, we employed a solid-phase microextraction (bioSPME) and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) procedure that enabled in vivo determinations in soft corals. Specifically, we researched the antibiotics Ofloxacin Sulfamethoxazole and Clarithromycin, the anti-inflammat...
Source: Chemosphere - March 30, 2024 Category: Chemistry Authors: Alessandro Becchi Marco Mantovani Marina Lasagni Elena Collina Simone Montano Paolo Galli Francesco Saliu Source Type: research
Application of non-lethal bioSPME-LC-MS/MS for the detection of human pharmaceuticals in soft corals: A survey at the North Nilandhe atoll (Maldives)
Chemosphere. 2024 Mar 28:141781. doi: 10.1016/j.chemosphere.2024.141781. Online ahead of print.ABSTRACTAt present the information regarding the occurrence of human pharmaceuticals (PhaCs) in coral reefs and their potential impacts on the associated fauna is limited. To optimize the collection of data in these delicate environments, we employed a solid-phase microextraction (bioSPME) and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) procedure that enabled in vivo determinations in soft corals. Specifically, we researched the antibiotics Ofloxacin Sulfamethoxazole and Clarithromycin, the anti-inflammat...
Source: Chemosphere - March 30, 2024 Category: Chemistry Authors: Alessandro Becchi Marco Mantovani Marina Lasagni Elena Collina Simone Montano Paolo Galli Francesco Saliu Source Type: research
Application of non-lethal bioSPME-LC-MS/MS for the detection of human pharmaceuticals in soft corals: A survey at the North Nilandhe atoll (Maldives)
Chemosphere. 2024 Mar 28:141781. doi: 10.1016/j.chemosphere.2024.141781. Online ahead of print.ABSTRACTAt present the information regarding the occurrence of human pharmaceuticals (PhaCs) in coral reefs and their potential impacts on the associated fauna is limited. To optimize the collection of data in these delicate environments, we employed a solid-phase microextraction (bioSPME) and liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) procedure that enabled in vivo determinations in soft corals. Specifically, we researched the antibiotics Ofloxacin Sulfamethoxazole and Clarithromycin, the anti-inflammat...
Source: Chemosphere - March 30, 2024 Category: Chemistry Authors: Alessandro Becchi Marco Mantovani Marina Lasagni Elena Collina Simone Montano Paolo Galli Francesco Saliu Source Type: research
