Pharmacological interventions for asymptomatic carotid stenosis
CONCLUSIONS: Although there is no high-certainty evidence to support pharmacological intervention, this does not mean that pharmacological treatments are ineffective in preventing ischaemic cerebral events, morbidity, and mortality. High-quality RCTs are needed to better inform the best medical treatment that may reduce the burden of carotid stenosis. In the interim, clinicians will have to use other sources of information.PMID:37565307 | PMC:PMC10401652 | DOI:10.1002/14651858.CD013573.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Caroline Nb Clezar Carolina Dq Flumignan Nicolle Cassola Luis Cu Nakano Virginia Fm Trevisani Ronald Lg Flumignan Source Type: research

GSE195525 Single cell RNA-seq for bone marrow mononuclear cells from CAR-T therapy received DLBCL patient
Contributor : Yuzhuo YangSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate whether metoprolol treatment could affect immune cells population and proinflammatory gene expression in bone marrow mononuclear cells from CAR-T therapy received DLBCL patient (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - July 31, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

GSE195524 Transcriptome and translatome of killing supernatant cultured human monocytes
Contributors : Yuzhuo Yang ; Gang XuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate whether metoprolol treatment could affect the transcriptome and translatome of killing supernatant cultured human monocytes (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - July 31, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

Occurrence and removal rate of typical pharmaceuticals and personal care products (PPCPs) in an urban wastewater treatment plant in Beijing, China
Chemosphere. 2023 Jul 24:139644. doi: 10.1016/j.chemosphere.2023.139644. Online ahead of print.ABSTRACTThe occurrence and removal rate of 52 typical pharmaceuticals and personal care products (PPCPs) were investigated in a wastewater treatment plant in Beijing, China. Thirty-three PPCPs were found in the influent, with caffeine (CF, 11387.0 ng L-1) being the most abundant, followed by N,N-diethyl-meta-toluamide (DEET, 9568.4 ng L-1), metoprolol (MTP, 930.2 ng L-1), and diclofenac (DF, 710.3 ng L-1). After treatment processes, the cumulative concentration of PPCPs decreased from 2.54 × 104 ng L-1 to 1.44 × 103 ng L-1, wit...
Source: Chemosphere - July 26, 2023 Category: Chemistry Authors: Jia Liu Simin Ge Peng Shao Jianfeng Wang Yanju Liu Wei Wei Can He Lilan Zhang Source Type: research

Occurrence and removal rate of typical pharmaceuticals and personal care products (PPCPs) in an urban wastewater treatment plant in Beijing, China
Chemosphere. 2023 Jul 24:139644. doi: 10.1016/j.chemosphere.2023.139644. Online ahead of print.ABSTRACTThe occurrence and removal rate of 52 typical pharmaceuticals and personal care products (PPCPs) were investigated in a wastewater treatment plant in Beijing, China. Thirty-three PPCPs were found in the influent, with caffeine (CF, 11387.0 ng L-1) being the most abundant, followed by N,N-diethyl-meta-toluamide (DEET, 9568.4 ng L-1), metoprolol (MTP, 930.2 ng L-1), and diclofenac (DF, 710.3 ng L-1). After treatment processes, the cumulative concentration of PPCPs decreased from 2.54 × 104 ng L-1 to 1.44 × 103 ng L-1, wit...
Source: Chemosphere - July 26, 2023 Category: Chemistry Authors: Jia Liu Simin Ge Peng Shao Jianfeng Wang Yanju Liu Wei Wei Can He Lilan Zhang Source Type: research

Occurrence and removal rate of typical pharmaceuticals and personal care products (PPCPs) in an urban wastewater treatment plant in Beijing, China
Chemosphere. 2023 Jul 24:139644. doi: 10.1016/j.chemosphere.2023.139644. Online ahead of print.ABSTRACTThe occurrence and removal rate of 52 typical pharmaceuticals and personal care products (PPCPs) were investigated in a wastewater treatment plant in Beijing, China. Thirty-three PPCPs were found in the influent, with caffeine (CF, 11387.0 ng L-1) being the most abundant, followed by N,N-diethyl-meta-toluamide (DEET, 9568.4 ng L-1), metoprolol (MTP, 930.2 ng L-1), and diclofenac (DF, 710.3 ng L-1). After treatment processes, the cumulative concentration of PPCPs decreased from 2.54 × 104 ng L-1 to 1.44 × 103 ng L-1, wit...
Source: Chemosphere - July 26, 2023 Category: Chemistry Authors: Jia Liu Simin Ge Peng Shao Jianfeng Wang Yanju Liu Wei Wei Can He Lilan Zhang Source Type: research

Occurrence and removal rate of typical pharmaceuticals and personal care products (PPCPs) in an urban wastewater treatment plant in Beijing, China
Chemosphere. 2023 Jul 24:139644. doi: 10.1016/j.chemosphere.2023.139644. Online ahead of print.ABSTRACTThe occurrence and removal rate of 52 typical pharmaceuticals and personal care products (PPCPs) were investigated in a wastewater treatment plant in Beijing, China. Thirty-three PPCPs were found in the influent, with caffeine (CF, 11387.0 ng L-1) being the most abundant, followed by N,N-diethyl-meta-toluamide (DEET, 9568.4 ng L-1), metoprolol (MTP, 930.2 ng L-1), and diclofenac (DF, 710.3 ng L-1). After treatment processes, the cumulative concentration of PPCPs decreased from 2.54 × 104 ng L-1 to 1.44 × 103 ng L-1, wit...
Source: Chemosphere - July 26, 2023 Category: Chemistry Authors: Jia Liu Simin Ge Peng Shao Jianfeng Wang Yanju Liu Wei Wei Can He Lilan Zhang Source Type: research

Comparison of primary care prescriptions for old and very old hypertensive patients
DISCUSSION: Prescribing preferences to old and very old patients mostly showed slight differences. Almost half of prescriptions comprising antihypertensive monotherapy might imply hesitancy to prescribe combinations. Overuse of risky drugs such as furosemide in both groups, especially in the very elderly, requires more attention.PMID:37476867 | DOI:10.55730/1300-0144.5618 (Source: Atherosclerosis)
Source: Atherosclerosis - July 21, 2023 Category: Cardiology Authors: Selcan T ülü Çolak Caner V ızdıklar Mert Ka şkal Volkan Ayd ın Ömer Ataç Ahmet Ak ıcı Source Type: research

Comparison of primary care prescriptions for old and very old hypertensive patients
DISCUSSION: Prescribing preferences to old and very old patients mostly showed slight differences. Almost half of prescriptions comprising antihypertensive monotherapy might imply hesitancy to prescribe combinations. Overuse of risky drugs such as furosemide in both groups, especially in the very elderly, requires more attention.PMID:37476867 | DOI:10.55730/1300-0144.5618 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Selcan T ülü Çolak Caner V ızdıklar Mert Ka şkal Volkan Ayd ın Ömer Ataç Ahmet Ak ıcı Source Type: research

Comparison of primary care prescriptions for old and very old hypertensive patients
DISCUSSION: Prescribing preferences to old and very old patients mostly showed slight differences. Almost half of prescriptions comprising antihypertensive monotherapy might imply hesitancy to prescribe combinations. Overuse of risky drugs such as furosemide in both groups, especially in the very elderly, requires more attention.PMID:37476867 | DOI:10.55730/1300-0144.5618 (Source: Atherosclerosis)
Source: Atherosclerosis - July 21, 2023 Category: Cardiology Authors: Selcan T ülü Çolak Caner V ızdıklar Mert Ka şkal Volkan Ayd ın Ömer Ataç Ahmet Ak ıcı Source Type: research

Comparison of primary care prescriptions for old and very old hypertensive patients
DISCUSSION: Prescribing preferences to old and very old patients mostly showed slight differences. Almost half of prescriptions comprising antihypertensive monotherapy might imply hesitancy to prescribe combinations. Overuse of risky drugs such as furosemide in both groups, especially in the very elderly, requires more attention.PMID:37476867 | DOI:10.55730/1300-0144.5618 (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Selcan T ülü Çolak Caner V ızdıklar Mert Ka şkal Volkan Ayd ın Ömer Ataç Ahmet Ak ıcı Source Type: research