Approaching the complexity of Crimean-Congo hemorrhagic fever virus serology: A study in swine
J Virol Methods. 2024 Mar 12;326:114915. doi: 10.1016/j.jviromet.2024.114915. Online ahead of print.ABSTRACTCrimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne zoonotic orthonairovirus of public health concern and widespread geographic distribution. Several animal species are known to seroconvert after infection with CCHFV without showing clinical symptoms. The commercial availability of a multi-species ELISA has led to an increase in recent serosurveillance studies as well as in the range of species reported to be exposed to CCHFV in the field, including wild boar (Sus scrofa). However, development and validatio...
Source: Journal of Virological Methods - March 13, 2024 Category: Virology Authors: Caroline Bost Sabrina Castro-Scholten Balal Sadeghi David Cano-Terriza Mario Fr ías Sa úl Jiménez-Ruiz Martin H Groschup Ignacio Garc ía-Bocanegra Kerstin Fischer Source Type: research

Approaching the complexity of Crimean-Congo hemorrhagic fever virus serology: A study in swine
J Virol Methods. 2024 Mar 12;326:114915. doi: 10.1016/j.jviromet.2024.114915. Online ahead of print.ABSTRACTCrimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne zoonotic orthonairovirus of public health concern and widespread geographic distribution. Several animal species are known to seroconvert after infection with CCHFV without showing clinical symptoms. The commercial availability of a multi-species ELISA has led to an increase in recent serosurveillance studies as well as in the range of species reported to be exposed to CCHFV in the field, including wild boar (Sus scrofa). However, development and validatio...
Source: Journal of Virological Methods - March 13, 2024 Category: Virology Authors: Caroline Bost Sabrina Castro-Scholten Balal Sadeghi David Cano-Terriza Mario Fr ías Sa úl Jiménez-Ruiz Martin H Groschup Ignacio Garc ía-Bocanegra Kerstin Fischer Source Type: research

Viruses, Vol. 16, Pages 444: The Prevalence of Tick-Borne Encephalitis Virus in Wild Rodents Captured in Tick-Borne Encephalitis Foci in Highly Endemic Lithuania
This study shows that wild rodents are suitable sentinel animals to confirm TBEV foci. In addition, the study results demonstrate that sample cultivation in cell culture is a highly efficient method for increasing TBEV viral load to detectable quantities. (Source: Viruses)
Source: Viruses - March 13, 2024 Category: Virology Authors: Evelina Simkute Arnoldas Pautienius Juozas Grigas Marina Sidorenko Jana Radzijevskaja Algimantas Paulauskas Arunas Stankevicius Tags: Article Source Type: research

Editorial: Treatment of tick-borne diseases: current status, challenges, and global perspectives
(Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 12, 2024 Category: Drugs & Pharmacology Source Type: research

Genotyping of ticks: first molecular report of Hyalomma asiaticum and molecular detection of tick-borne bacteria in ticks and blood from Khyber Pakhtunkhwa, Pakistan
This study presented the first genetic report of Hy. asiaticum ticks in Pakistan. Moreover, genetically confirmed tick species were molecularly analyzed by PCR for detection of Rickettsiales DNA using partial fragments of 16S rDNA, 190-kDa outer membrane protein A (ompA), and 120-kDa outer membrane protein B (ompB) genes. In addition, blood samples were analyzed to identify Rickettsiales bacteria using the aforementioned genes. Rickettsiales bacteria were found in 24/126 (19.05%) ticks and 4/16 (25.00%) in symptomatic cattle’s blood. The obtained ompA and ompB sequences from Hy. asiaticum ticks showed 99.73%–99.87% wit...
Source: Frontiers in cellular and infection microbiology - March 12, 2024 Category: Microbiology Source Type: research

Leading report of molecular prevalence of tick borne Anaplasma marginale and Theileria ovis in yaks (Bos grunniens) from Pakistan
In conclusion, this is the first report that yaks residing the Gilgit-Baltistan region in Pakistan are infected with Theileria ovis and Anaplasma marginale. Similar larger scales studies are recommended in various regions of Gilgit-Baltistan to document the infection rates of these parasites to formulate strategies that will lead to the effective control of these pathogens.PMID:38466437 | DOI:10.1007/s00203-024-03916-6 (Source: Archives of Microbiology)
Source: Archives of Microbiology - March 11, 2024 Category: Microbiology Authors: Muqaddas Nawaz Rehmat Ullah Zia Ur Rehman Muhammad Naeem Afshan Khan Mohammed Bourhia Muhammad Mudassir Sohail Takbir Ali Adil Khan Tanveer Hussain Furhan Iqbal Source Type: research

A Case of Tick-borne Disease with Yezo Virus and Borrelia miyamotoi Coinfection
Intern Med. 2024 Mar 11. doi: 10.2169/internalmedicine.3225-23. Online ahead of print.ABSTRACTYezo virus is a novel virus transmitted by tick bites that causes fever with thrombocytopenia. To date, two reports have been published on patients with Yezo virus infection. However, the clinical characteristics of Yezo virus infection remain unclear. A patient who presented with fever, fatigue, headaches, and muscle pain and was admitted to our hospital. The patient had thrombocytopenia, leukopenia, and elevated liver enzyme and serum ferritin levels. The patient was diagnosed with Yezo virus and Borrelia miyamotoi coinfection b...
Source: Internal Medicine - March 10, 2024 Category: Internal Medicine Authors: Keiko Suzuki Satoshi Suzuki Hiroki Yamaguchi Yasutaka Kakinoki Source Type: research

Green cities and vector-borne diseases: emerging concerns and opportunities
Euro Surveill. 2024 Mar;29(10). doi: 10.2807/1560-7917.ES.2024.29.10.2300548.ABSTRACTAligned with the Sustainable Development Goals, nature-based solutions such as urban greening e.g. public gardens, urban forests, parks and street trees, which aim to protect, sustainably manage or restore an ecosystem, have emerged as a promising tool for improving the health and well-being of an ever-increasing urban population. While urban greening efforts have undeniable benefits for human health and the biological communities inhabiting these green zones, disease vector populations may also be affected, possibly promoting greater path...
Source: Euro Surveill - March 8, 2024 Category: Infectious Diseases Authors: Florence Fournet Fr édéric Simard Didier Fontenille Source Type: research

Virus-like particles of louping ill virus elicit potent neutralizing antibodies targeting multimers of viral envelope protein
This study aimed to develop high-efficacy non-infectious protein-based vaccine candidates. Specifically, soluble envelope protein (sE), and virus-like particles (VLPs), comprised of the precursor of membrane and envelope proteins, were generated, characterized, and studied for their immunogenicity in mice. Results showed that the VLPs induced more potent virus neutralizing response compared to sE, even though the total anti-envelope IgG content induced by the two antigens was similar. Depletion of anti-monomeric E protein antibodies from mouse immune sera suggested that the neutralizing antibodies elicited by the VLPs targ...
Source: Vaccine - March 8, 2024 Category: Allergy & Immunology Authors: Rapeepat Tandavanitj Chayanee Setthapramote Giuditta De Lorenzo Ricardo Sanchez-Velazquez Jordan J Clark Mara Rocchi Colin McInnes Alain Kohl Arvind H Patel Source Type: research

Green cities and vector-borne diseases: emerging concerns and opportunities
Euro Surveill. 2024 Mar;29(10). doi: 10.2807/1560-7917.ES.2024.29.10.2300548.ABSTRACTAligned with the Sustainable Development Goals, nature-based solutions such as urban greening e.g. public gardens, urban forests, parks and street trees, which aim to protect, sustainably manage or restore an ecosystem, have emerged as a promising tool for improving the health and well-being of an ever-increasing urban population. While urban greening efforts have undeniable benefits for human health and the biological communities inhabiting these green zones, disease vector populations may also be affected, possibly promoting greater path...
Source: Euro Surveill - March 8, 2024 Category: Infectious Diseases Authors: Florence Fournet Fr édéric Simard Didier Fontenille Source Type: research