Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020.
AT Abstract We whole-genome sequenced 55 SARS-CoV-2 isolates from Germany to investigate SARS-CoV-2 outbreaks in 2020 in the Heinsberg district and Düsseldorf. While the genetic structure of the Heinsberg outbreak indicates a clonal origin, reflecting superspreading dynamics from mid-February during the carnival season, distinct viral strains were circulating in Düsseldorf in March, reflecting the city's international links. Limited detection of Heinsberg strains in the Düsseldorf area despite geographical proximity may reflect efficient containment and contact-tracing efforts. PMID: 32524946 ...
Source: Euro Surveill - June 1, 2020 Category: Infectious Diseases Authors: Walker A, Houwaart T, Wienemann T, Vasconcelos MK, Strelow D, Senff T, Hülse L, Adams O, Andree M, Hauka S, Feldt T, Jensen BE, Keitel V, Kindgen-Milles D, Timm J, Pfeffer K, Dilthey AT Tags: Euro Surveill Source Type: research

2017/18 and 2018/19 seasonal influenza vaccine safety surveillance, Canadian National Vaccine Safety (CANVAS) Network.
ConclusionIn 2017/18 and 2018/19, higher rates of events were reported following seasonal influenza vaccination than in the pre-vaccination period. This signal was associated with several seasonal influenza vaccine products. PMID: 32524947 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 1, 2020 Category: Infectious Diseases Authors: Bettinger JA, De Serres G, Valiquette L, Vanderkooi OG, Kellner JD, Coleman BL, Top KA, Isenor JE, McCarthy AE, Canadian Immunization Research Network Tags: Euro Surveill Source Type: research

High impact of COVID-19 in long-term care facilities, suggestion for monitoring in the EU/EEA, May 2020.
Paiva JA, Schneider E Abstract Residents in long-term care facilities (LTCF) are a vulnerable population group. Coronavirus disease (COVID-19)-related deaths in LTCF residents represent 30-60% of all COVID-19 deaths in many European countries. This situation demands that countries implement local and national testing, infection prevention and control, and monitoring programmes for COVID-19 in LTCF in order to identify clusters early, decrease the spread within and between facilities and reduce the size and severity of outbreaks. PMID: 32524949 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 1, 2020 Category: Infectious Diseases Authors: ECDC Public Health Emergency Team, Danis K, Fonteneau L, Georges S, Daniau C, Bernard-Stoecklin S, Domegan L, O'Donnell J, Hauge SH, Dequeker S, Vandael E, Van der Heyden J, Renard F, Sierra NB, Ricchizzi E, Schweickert B, Schmidt N, Abu Sin M, Eckmanns T Tags: Euro Surveill Source Type: research

Author's correction for Euro Surveill. 2020;25(10).
PMID: 32524952 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 1, 2020 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Infection prevention guidelines and considerations for paediatric risk groups when reopening primary schools during COVID-19 pandemic, Norway, April 2020.
Abstract In response to the coronavirus disease (COVID-19) pandemic, most countries implemented school closures. In Norway, schools closed on 13 March 2020. The evidence of effect on disease transmission was limited, while negative consequences were evident. Before reopening, risk-assessment for paediatric risk groups was performed, concluding that most children can attend school with few conditions requiring preventative homeschooling. We here present infection prevention and control guidelines for primary schools and recommendations for paediatric risk groups. PMID: 32524956 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 1, 2020 Category: Infectious Diseases Authors: Johansen TB, Astrup E, Jore S, Nilssen H, Dahlberg BB, Klingenberg C, Berg AS, Greve-Isdahl M Tags: Euro Surveill Source Type: research

SARS-CoV-2-related paediatric inflammatory multisystem syndrome, an epidemiological study, France, 1 March to 17 May 2020.
Abstract End of April 2020, French clinicians observed an increase in cases presenting with paediatric inflammatory multisystem syndrome (PIMS). Nationwide surveillance was set up and demonstrated temporospatial association with the coronavirus disease (COVID-19) epidemic for 156 reported cases as at 17 May: 108 were classified as confirmed (n = 79), probable (n = 16) or possible (n = 13) post-COVID-19 PIMS cases. A continuum of clinical features from Kawasaki-like disease to myocarditis was observed, requiring intensive care in 67% of cases. PMID: 32524957 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 1, 2020 Category: Infectious Diseases Authors: Belot A, Antona D, Renolleau S, Javouhey E, Hentgen V, Angoulvant F, Delacourt C, Iriart X, Ovaert C, Bader-Meunier B, Kone-Paut I, Levy-Bruhl D Tags: Euro Surveill Source Type: research

Incidence, Severity and Impact of Influenza: a joint meeting organised by the ISIRV Epidemiology Group and ECDC, Stockholm, 2019.
PMID: 31186076 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 14, 2019 Category: Infectious Diseases Authors: Rath B, Penttinen P Tags: Euro Surveill Source Type: research

Addendum for Euro Surveill. 2019;24(22).
PMID: 31186077 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 14, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Increase of scabies infestations, Norway, 2006 to 2018.
eng A Abstract Between October and December 2018, several clinicians in Norway reported an increase in scabies diagnoses. We compared data from the Norwegian Syndromic Surveillance System on medical consultations for mite infestations with scabies treatment sales data to investigate this reported increase. From 2013 to 2018, consultations and sales of scabies treatments had almost increased by threefold, particularly affecting young adults 15-29 years. We recommend to increase awareness among clinicians to ensure timely diagnosis and treatment. PMID: 31186078 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 14, 2019 Category: Infectious Diseases Authors: Amato E, Dansie LS, Grøneng GM, Blix HS, Bentele H, Veneti L, Stefanoff P, MacDonald E, Blystad HH, Soleng A Tags: Euro Surveill Source Type: research

Suspected cluster of Neisseria meningitidis W invasive disease in an elderly care home: do new laboratory methods aid public health action? United Kingdom, 2015.
Abstract In 2015, a suspected cluster of two invasive meningococcal disease (IMD) cases of serogroup W Neisseria meningitidis (MenW) occurred in elderly care home residents in England over 7 months; case investigations followed United Kingdom guidance. An incident control team reviewed epidemiological information. Phenotyping of case specimens informed public health action, including vaccination and throat swabs to assess carriage. Whole genome sequencing (WGS) was conducted on case and carrier isolates. Conventional phenotyping did not exclude a microbiological link between cases (case 1 W:2a:P1.5,2 and case 2 W:...
Source: Euro Surveill - June 14, 2019 Category: Infectious Diseases Authors: Lawler J, Lucidarme J, Parikh S, Smith L, Campbell H, Borrow R, Gray S, Foster K, Ladhani S Tags: Euro Surveill Source Type: research

Call for papers for a special issue on how point of care/point of impact testing (POCT/ POIT) and self-testing impact surveillance and public health - deadline extended to 30 June 2019.
PMID: 31164187 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Health crisis in Venezuela: Status of communicable diseases and implications for the European Union and European Economic Area, May 2019.
Abstract Re-emerging diseases outbreaks are being reported in Venezuela since 2012/13, following ongoing political and economic crisis. Healthcare system collapse has led to an increasing incidence and mortality from communicable diseases. Increasing movement of people between Venezuela and the European Union and European Economic Area (EU/EEA) creates a need for increased awareness of the infectious disease risks and requirements for appropriate investigation and treatment of individuals arriving from Venezuela; overall risk for EU/EEA citizens is low. PMID: 31164188 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Espinosa L, Mirinaviciute G Tags: Euro Surveill Source Type: research

Histamine food poisoning: a sudden, large outbreak linked to fresh yellowfin tuna from Reunion Island, France, April 2017.
We describe the outbreak to highlight the specific key points of this type of investigation. PMID: 31164189 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Velut G, Delon F, Mérigaud JP, Tong C, Duflos G, Boissan F, Watier-Grillot S, Boni M, Derkenne C, Dia A, Texier G, Vest P, Meynard JB, Fournier PE, Chesnay A, Pommier de Santi V Tags: Euro Surveill Source Type: research

Outbreak of Shiga toxin-producing Escherichia coli (STEC) O26 paediatric haemolytic uraemic syndrome (HUS) cases associated with the consumption of soft raw cow's milk cheeses, France, March to May 2019.
We report an outbreak of Shiga toxin-producing Escherichia coli (STEC) associated paediatric haemolytic uraemic syndrome linked to the consumption of raw cow's milk soft cheeses. From 25 March to 27 May 2019, 16 outbreak cases infected with STEC O26 (median age: 22 months) were identified. Interviews and trace-back investigations using loyalty cards identified the consumption of raw milk cheeses from a single producer. Trace-forward investigations revealed that these cheeses were internationally distributed. PMID: 31164190 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Jones G, Lefèvre S, Donguy MP, Nisavanh A, Terpant G, Fougère E, Vaissière E, Guinard A, Mailles A, de Valk H, Fila M, Tanné C, Le Borgne C, Weill FX, Bonacorsi S, Jourdan-Da Silva N, Mariani-Kurkdjian P Tags: Euro Surveill Source Type: research

Prevalence of asymptomatic Leishmania infection and associated risk factors, after an outbreak in the south-western Madrid region, Spain, 2015.
ConclusionsThe true number of infected individuals may be underestimated if only serological methods are used. The combination of WBA with IL-2 quantification may allow to better determine the prevalence of asymptomatic Leishmania infection, which would be useful in establishing control measures and in quantifying their impact. In our study, the use of WBA with IL-2 quantification also helped establish the risk factors that influence exposure to and infection by Leishmania. PMID: 31164191 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Ibarra-Meneses AV, Carrillo E, Nieto J, Sánchez C, Ortega S, Estirado A, Latasa Zamalloa P, Sanz JC, García-Comas L, Ordobás M, Moreno J Tags: Euro Surveill Source Type: research

Chlamydia trachomatis samples testing falsely negative in the Aptima Combo 2 test in Finland, 2019.
Abstract Since February 2019, over 160 Chlamydia trachomatis (CT) cases testing negative or equivocal by Aptima Combo 2 (AC2) but positive by Aptima CT test run with Panther instruments occurred in Finland. The AC2 test targets chlamydial 23S rRNA while the CT test targets 16S rRNA. Sequencing of 10 strains revealed a nucleotide substitution in 23S rRNA. The significance of this for the failure of the AC2 test to detect the variant is not yet known. PMID: 31164192 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Rantakokko-Jalava K, Hokynar K, Hieta N, Keskitalo A, Jokela P, Muotiala A, Jokiranta TS, Kuusela R, Sarkkinen H, Aittoniemi J, Vuorinen T, Hakanen AJ, Puolakkainen M Tags: Euro Surveill Source Type: research

Author's response: False-positive results with rapid diagnostic test for dengue in Thailand.
PMID: 31138360 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Kantele A Tags: Euro Surveill Source Type: research

West Nile virus infection in individuals with pre-existing Usutu virus immunity, northern Italy, 2018.
Abstract In 2018, there was a large West Nile virus (WNV) outbreak in northern Italy. We observed five atypical cases of WNV infection that were characterised by the presence of WNV RNA and WNV IgG at the time of diagnosis, but no IgM response during follow-up. Neutralisation assays demonstrated pre-existing Usutu virus immunity in all patients. Besides challenging diagnosis, the immunological crosstalk between the two viruses warrants further investigation on possible cross-protection or infection enhancement effects. PMID: 31138361 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Sinigaglia A, Pacenti M, Martello T, Pagni S, Franchin E, Barzon L Tags: Euro Surveill Source Type: research

The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019.
Abstract After no reported human cases of highly pathogenic avian influenza (HPAI) H7N9 for over a year, a case with severe disease occurred in late March 2019. Among HPAI H7N9 viral sequences, those recovered from the case and from environmental samples of a poultry slaughtering stall near their home formed a distinct clade from 2017 viral sequences. Several mutations possibly associated to antigenic drift occurred in the haemagglutinin gene, potentially warranting update of H7N9 vaccine strains. PMID: 31138362 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Yu D, Xiang G, Zhu W, Lei X, Li B, Meng Y, Yang L, Jiao H, Li X, Huang W, Wei H, Zhang Y, Hai Y, Zhang H, Yue H, Zou S, Zhao X, Li C, Ao D, Zhang Y, Tan M, Liu J, Zhang X, Gao GF, Meng L, Wang D Tags: Euro Surveill Source Type: research

Dating apps and websites as tools to reach anonymous sexual contacts during an outbreak of hepatitis A among men who have sex with men, Berlin, 2017.
ConclusionsDating apps provided a means to rapidly reach and influence a substantial number of MSM in Berlin and should complement case-based contact tracing among MSM in outbreak settings. Clicking on ads depended on platform and format used. PMID: 31138363 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Ruscher C, Werber D, Thoulass J, Zimmermann R, Eckardt M, Winter C, Sagebiel D Tags: Euro Surveill Source Type: research

Letter to the editor: False-positive results with rapid diagnostic tests (RDT) for dengue.
PMID: 31138364 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Javelle E, Gautret P, Leparc-Goffart I Tags: Euro Surveill Source Type: research

Listeriosis in Spain based on hospitalisation records, 1997 to 2015: need for greater awareness.
ConclusionListeriosis is an emergent public health problem in Spain that calls for targeted action. Further prevention strategies are urgently needed, including food safety education and messaging for all at-risk groups. PMID: 31138365 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Herrador Z, Gherasim A, López-Vélez R, Benito A Tags: Euro Surveill Source Type: research

Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019.
We describe a ceftriaxone-resistant Salmonella Typhi bacteraemia in a pregnant woman returning from a family visit in Pakistan. Whole genome sequencing confirmed similarity to a Pakistani outbreak clone. Pregnancy and unawareness of this outbreak delayed appropriate antibiotic therapy. Concurrently, we detected faecal carriage of a carbapenemase-producing Escherichia coli. Awareness of the ongoing outbreak should affect empiric treatment of typhoid fever and hygiene precautions in travellers returning from Pakistan. Meropenem may be warranted in severe cases. PMID: 31138366 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Engsbro AL, Riis Jespersen HS, Goldschmidt MI, Mollerup S, Worning P, Pedersen MS, Westh H, Schneider UV Tags: Euro Surveill Source Type: research

Lyme neuroborreliosis epidemiology in Sweden 2010 to 2014: clinical microbiology laboratories are a better data source than the hospital discharge diagnosis register.
ConclusionThe hospital discharge register was unsuitable for surveillance of neuroborreliosis, whereas laboratory-based reporting was a feasible alternative. In 2018, the European Commission included Lyme neuroborreliosis on the list of diseases under epidemiological surveillance. PMID: 31115310 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Dahl V, Wisell KT, Giske CG, Tegnell A, Wallensten A Tags: Euro Surveill Source Type: research

Use of the moving epidemic method (MEM) to assess national surveillance data for respiratory syncytial virus (RSV) in the Netherlands, 2005 to 2017.
ConclusionsOur findings provide baseline information for immunisation advisory groups. The possibility of employing MEM to monitor RSV epidemics allows prospective, nearly real-time use of surveillance data. PMID: 31115311 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Vos LM, Teirlinck AC, Lozano JE, Vega T, Donker GA, Hoepelman AI, Bont LJ, Oosterheert JJ, Meijer A Tags: Euro Surveill Source Type: research

Resistance proportions for eight priority antibiotic-bacterium combinations in OECD, EU/EEA and G20 countries 2000 to 2030: a modelling study.
ConclusionIf current trends continue, resistance proportions are projected to marginally increase in the coming years. The estimates indicate there is significant heterogeneity in resistance proportions across countries and antibiotic-bacterium combinations. PMID: 31115312 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Cravo Oliveira Hashiguchi T, Ait Ouakrim D, Padget M, Cassini A, Cecchini M Tags: Euro Surveill Source Type: research

Factors associated with Legionnaires' disease recurrence in hotel and holiday rental accommodation sites.
ConclusionAccommodation size and previous TALD cases were predictive of further Legionnaires' disease cases after implementation of control measures. PMID: 31115313 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Beauté J, Sandin S, de Jong B, Hallström LP, Robesyn E, Giesecke J, Sparén P, On Behalf Of The European Legionnaires' Disease Surveillance Network Tags: Euro Surveill Source Type: research

Measures to control protracted large Lassa fever outbreak in Nigeria, 1 January to 28 April 2019.
We describe the various outbreak responses that have been implemented, including establishment of emergency thresholds and guidelines for case management. PMID: 31115314 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Dan-Nwafor CC, Furuse Y, Ilori EA, Ipadeola O, Akabike KO, Ahumibe A, Ukponu W, Bakare L, Okwor TJ, Joseph G, Mba NG, Akano A, Olayinka AT, Okoli I, Okea RA, Makava F, Ugbogulu N, Oladele S, Namara G, Muwanguzi EN, Naidoo D, Mutbam SK, Okudo I, Woldetsadi Tags: Euro Surveill Source Type: research

A cluster analysis of serious adverse event reports after human papillomavirus (HPV) vaccination in Danish girls and young women, September 2009 to August 2017.
ConclusionsNon-specific symptoms including headache, fatigue and dizziness feature prominently in serious AE reports from females in Denmark. Our analysis identified a cluster of reports, likely media stimulated, with a focus on symptoms of CFS and POTS. PMID: 31088598 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Ward D, Thorsen NM, Frisch M, Valentiner-Branth P, Mølbak K, Hviid A Tags: Euro Surveill Source Type: research

Contact tracing following measles exposure on three international flights, Germany, 2017.
We report two events of contact tracing initiated in Germany after two individuals with measles travelled on three international flights. In one event, contact tracing was initiated late because laboratory confirmation of a clinically diagnosed measles case was awaited unnecessarily. Accessing passenger contact data was difficult in both events because of data protection issues with the airline which was not based in Germany. In both events, passengers were not reached in time to provide PEP, and one event resulted in at least two secondary measles cases. As all passengers were reached before the incubation period ended, t...
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Thole S, Kalhoefer D, An der Heiden M, Nordmann D, Daniels-Haardt I, Jurke A Tags: Euro Surveill Source Type: research

Piloting a surveillance system for HIV drug resistance in the European Union.
ConclusionWe conclude that standard reporting of HIVDR data was feasible in the participating countries. Legal barriers for data sharing, consensus on definitions and standardisation of interpretation algorithms should be clarified in the process of enhancing European-wide HIV surveillance with drug resistance information. PMID: 31088600 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: van de Laar MJ, Bosman A, Pharris A, Andersson E, Assoumou L, Ay E, Bannert N, Bartmeyer B, Brady M, Chaix ML, Descamps D, Dauwe K, Fonager J, Hauser A, Lunar M, Mezei M, Neary M, Poljak M, van Sighem A, Verhofstede C, Amato-Gauci AJ, Broberg EK Tags: Euro Surveill Source Type: research

Emergence of ceftazidime-avibactam-resistant Klebsiella pneumoniae during treatment, Finland, December 2018.
O, Jalava J Abstract In December 2018, a ceftazidime-avibactam (CAZ-AVI)-resistant KPC-2-producing Klebsiella pneumoniae strain was isolated in Finland. CAZ-AVI resistance was observed 34 days after CAZ-AVI treatment in a trauma patient transferred from a hospital in Greece who had been colonised with blaKPC-2-producing K. pneumoniae ST39, and later developed a bloodstream infection. The CAZ-AVI-resistant strain contained a novel 15 amino acid insertion in the KPC-2 protein causing structural changes proximal to the KPC-2 active site. PMID: 31088601 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Räisänen K, Koivula I, Ilmavirta H, Puranen S, Kallonen T, Lyytikäinen O, Jalava J Tags: Euro Surveill Source Type: research

A new Borrelia on the block: Borrelia miyamotoi - a human health risk?
ConclusionsWith co-infection of tick-borne pathogens being commonplace, diagnostic improvements remain important. Developing in vivo models might allow more insight into human pathogenesis. Continued ecological and human case studies are key to better epidemiological understanding, guiding intervention strategies. PMID: 31064634 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Cutler S, Vayssier-Taussat M, Estrada-Peña A, Potkonjak A, Mihalca AD, Zeller H Tags: Euro Surveill Source Type: research

Genetic diversity and delineation of Salmonella Agona outbreak strains by next generation sequencing, Bavaria, Germany, 1993 to 2018.
ConclusionEven for S. Agona, species-level cgMLST can produce reasonable resolution, being standardisable by public health laboratories. For single samples or homogeneous sample sets, higher resolution by serovar-specific cgMLST or SNP genotyping can facilitate outbreak investigations. PMID: 31064635 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Dangel A, Berger A, Messelhäußer U, Konrad R, Hörmansdorfer S, Ackermann N, Sing A Tags: Euro Surveill Source Type: research

Molecular identification of the source of an uncommon tularaemia outbreak, Germany, autumn 2016.
ConclusionThe discovered source of infection and the transmission scenario of F. tularensis in this outbreak have not been observed previously and suggest the need for additional hygienic precautionary measures when processing and consuming freshly pressed must. PMID: 31064636 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Jacob D, Köppen K, Radonić A, Haldemann B, Zanger P, Heuner K, Grunow R Tags: Euro Surveill Source Type: research

Disease burden of varicella versus other vaccine-preventable diseases before introduction of vaccination into the national immunisation programme in the Netherlands.
ConclusionsWhen considering the introduction of a new vaccine in the NIP, BoD is usually estimated in isolation. The current approach assesses BoD in relation to other vaccine-preventable diseases' BoD, which may help national advisory committees on immunisation and policymakers to set vaccination priorities. PMID: 31064637 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: van Lier A, de Gier B, McDonald SA, Mangen MJ, van Wijhe M, Sanders EAM, Kretzschmar ME, van Vliet H, de Melker HE Tags: Euro Surveill Source Type: research

Challenges of investigating a large food-borne norovirus outbreak across all branches of a restaurant group in the United Kingdom, October 2016.
Abstract During October and November 2016, over 1,000 customers and staff reported gastroenteritis after eating at all 23 branches of a restaurant group in the United Kingdom. The outbreak coincided with a new menu launch and norovirus was identified as the causative agent. We conducted four retrospective cohort studies; one among all restaurant staff and three in customers at four branches. We investigated the dishes consumed, reviewed recipes, interviewed chefs and inspected restaurants to identify common ingredients and preparation methods for implicated dishes. Investigations were complicated by three public h...
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Morgan M, Watts V, Allen D, Curtis D, Kirolos A, Macdonald N, Maslen E, Morgan D, Saei A, Sedgwick J, Stevenson J, Turbitt D, Vivancos R, Waugh C, Williams C, Decraene V Tags: Euro Surveill Source Type: research

Estimating age-specific vaccine effectiveness using data from a large measles outbreak in Berlin, Germany, 2014/15: evidence for waning immunity.
ConclusionVE for MCV2 was generally high, but lower in those aged 31-42 years old. The estimated proportion with MCV2 should have led to sufficient herd immunity in those aged 31-42 years old. Thus, lower VE cannot be fully explained by natural immunity, suggesting presence of waning immunity. PMID: 31039834 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Bitzegeio J, Majowicz S, Matysiak-Klose D, Sagebiel D, Werber D Tags: Euro Surveill Source Type: research

Measles outbreak in Gothenburg urban area, Sweden, 2017 to 2018: low viral load in breakthrough infections.
The objective of this study was to compare measles RNA levels between naïve (i.e. primary) and breakthrough infections. We also propose a fast provisional classification of breakthrough infections. Medical records were reviewed and real-time PCR-positive samples genotyped. Cases were classified as naïve, breakthrough or vaccine infections. We compared clinical symptoms and measles RNA cycle threshold (Ct) values between breakthrough and naïve infections. Sixteen of 28 confirmed cases of measles in this outbreak were breakthrough infections. A fast provisional classification, based on previous history of meas...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Sundell N, Dotevall L, Sansone M, Andersson M, Lindh M, Wahlberg T, Tyrberg T, Westin J, Liljeqvist JÅ, Bergström T, Studahl M, Andersson LM Tags: Euro Surveill Source Type: research

Spatiotemporal distribution and determinants of measles incidence during a large outbreak, Italy, September 2016 to July 2018.
ConclusionThe spread of measles between September 2016 and July 2018 in Italy indicates the need to improve VC and to explore further how societal and other parameters might be linked to incidence. PMID: 31039836 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Andrianou XD, Del Manso M, Bella A, Vescio MF, Baggieri M, Rota MC, Pezzotti P, Filia A Tags: Euro Surveill Source Type: research

One Health approach for West Nile virus surveillance in the European Union: relevance of equine data for blood safety.
Abstract West Nile virus (WNV) infection is notifiable in humans and equids in the European Union (EU). An area where a human case is detected is considered affected until the end of the mosquito transmission season (week 48) and blood safety measures have to be implemented. We used human and equine case notifications between 2013 and 2017 to define the WNV distribution in the EU and to investigate the relevance of using equine cases as a complementary trigger for blood safety measures. Adding areas with equine cases to the definition of an affected area would have a major impact on blood safety measures. Adding a...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Young JJ, Coulombier D, Domanović D, European Union West Nile Fever Working Group, Zeller H, Gossner CM Tags: Euro Surveill Source Type: research

Detection of colistin resistance mcr-1 gene in Salmonella enterica serovar Rissen isolated from mussels, Spain, 2012- to 2016.
Abstract Nineteen Salmonella strains were isolated from 5,907 randomly selected mussel samples during a monitoring programme for the presence of Salmonella in shellfish in Galicia, north-west Spain (2012-16). Serovars, sequence type and antimicrobial resistance genes were determined through genome sequencing. Presence of the mcr-1 gene in one strain belonging to serovar Rissen and ST-469 was identified. The mcr-1 gene had not been isolated previously in environmental Salmonella isolated from mussels in Spain. PMID: 31014417 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Lozano-Leon A, Garcia-Omil C, Dalama J, Rodriguez-Souto R, Martinez-Urtaza J, Gonzalez-Escalona N Tags: Euro Surveill Source Type: research

Outbreak of Shiga toxin-producing Escherichia coli O157:H7 linked to raw drinking milk resolved by rapid application of advanced pathogen characterisation methods, England, August to October 2017.
Abstract An outbreak of Shiga toxin-producing Escherichia coli (STEC) O157:H7 occurred on the Isle of Wight between August and October 2017. Of the seven cases linked to the outbreak, five were identified through the statutory notification process and two were identified through national surveillance of whole genome sequencing data. Enhanced surveillance questionnaires established a common link to a farm, and link to the likely food vehicle, raw drinking milk (RDM). Microbiological investigations, including PCR, identified the presence of STEC O157:H7 in samples of RDM. Analysis of core genome single nucleotide po...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Treacy J, Jenkins C, Paranthaman K, Jorgensen F, Mueller-Doblies D, Anjum M, Kaindama L, Hartman H, Kirchner M, Carson T, Kar-Purkayastha I Tags: Euro Surveill Source Type: research

Author's correction for Euro Surveill. 2019;24(14).
PMID: 31017085 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Group A rotavirus surveillance before vaccine introduction in Italy, September 2014 to August 2017.
ConclusionsThe emergence of G12P[8] rotavirus in Italy, as in other countries, marks this genotype as the sixth most common human genotype. Continuous surveillance of RVA strains and monitoring of circulating genotypes are important for a better understanding of rotavirus evolution and genotype distribution, particularly regarding strains that may emerge from reassortment events. PMID: 30994104 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Ianiro G, Micolano R, Di Bartolo I, Scavia G, Monini M, RotaNet-Italy Study Group Tags: Euro Surveill Source Type: research

Changing epidemiology of meticillin-resistant Staphylococcus aureus in 42 hospitals in the Dutch-German border region, 2012 to 2016: results of the search-and-follow-policy.
We describe MRSA colonisation/infection and bacteraemia rate trends in Dutch-German border region hospitals (NL-DE-BRH) in 2012-16.MethodsAll 42 NL-DE BRH (8 NL-BRH, 34 DE-BRH) within the cross-border network EurSafety Health-net provided surveillance data (on average ca 620,000 annual hospital admissions, of these 68.0% in Germany). Guidelines defining risk for MRSA colonisation/infection were reviewed. MRSA-related parameters and healthcare utilisation indicators were derived. Medians over the study period were compared between NL- and DE-BRH.ResultsMeasures for MRSA cases were similar in both countries, however defining...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Jurke A, Daniels-Haardt I, Silvis W, Berends MS, Glasner C, Becker K, Köck R, Friedrich AW Tags: Euro Surveill Source Type: research

Missed opportunities for HIV testing in people diagnosed with HIV, Estonia, 2014 to 2015.
ConclusionsThe HIV testing rate in the 2 years before an HIV diagnosis was very low, even in the presence of an HIV indicator condition. This emphasises the importance of implementing the Estonian HIV testing guidelines. PMID: 30994106 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Rüütel K, Lemsalu L, Lätt S, Epštein J, On Behalf Of OptTEST By HiE Tags: Euro Surveill Source Type: research

Children under 10 years of age were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic in Canada: ‎possible cohort effect following the 2009 influenza pandemic.
Children under 10 years of age were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic in Canada: ‎possible cohort effect following the 2009 influenza pandemic. Euro Surveill. 2019 Apr;24(15): Authors: Skowronski DM, Leir S, De Serres G, Murti M, Dickinson JA, Winter AL, Olsha R, Croxen MA, Drews SJ, Charest H, Martineau C, Sabaiduc S, Bastien N, Li Y, Petric M, Jassem A, Krajden M, Gubbay JB Abstract IntroductionFindings from the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) suggest children were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic.A...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Skowronski DM, Leir S, De Serres G, Murti M, Dickinson JA, Winter AL, Olsha R, Croxen MA, Drews SJ, Charest H, Martineau C, Sabaiduc S, Bastien N, Li Y, Petric M, Jassem A, Krajden M, Gubbay JB Tags: Euro Surveill Source Type: research

Outbreak of hepatitis A virus infection in Taiwan, June 2015 to September 2017.
Abstract The Taiwan Centers for Disease Control (CDC) were notified of increasing acute hepatitis A (AHA) in June 2015. Serum and/or stool from AHA patients and sewage samples were tested for hepatitis A virus (HAV). We defined outbreak cases as AHA patients with illness onset after June 2015 and with an HAV sequence less than 0.5% different from that of the TA-15 outbreak strain. We analysed characteristics and food exposures between outbreak and non-outbreak cases between January 2014 (start of enhanced surveillance) and February 2016. From June 2015 to September 2017, there were 1,563 AHA patients...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Chen WC, Chiang PH, Liao YH, Huang LC, Hsieh YJ, Chiu CM, Lo YC, Yang CH, Yang JY Tags: Euro Surveill Source Type: research

Mortality attributable to seasonal influenza in Greece, 2013 to 2017: variation by type/subtype and age, and a possible harvesting effect.
ConclusionsStudies of influenza-attributable mortality need to consider distributed-lag effects, stratify by age group and adjust both for circulating influenza virus types/subtypes and daily mean temperatures, in order to produce reliable estimates. Our approach addresses these issues, is readily applicable in the context of influenza surveillance, and can be useful for other countries. PMID: 30968823 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Lytras T, Pantavou K, Mouratidou E, Tsiodras S Tags: Euro Surveill Source Type: research