VIM-1 carbapenemase-producing Escherichia coli isolated from retail seafood, Germany 2016.
Abstract Carbapenems belong to the group of last resort antibiotics in human medicine. Therefore, the emergence of growing numbers of carbapenemase-producing bacteria in food-producing animals or the environment is worrying and an important concern for the public health sector. In the present study, a set of 45 Enterobacteriaceae isolated from German retail seafood (clams and shrimps), sampled in 2016, were investigated by real-time PCR for the presence of carbapenemase-producing bacteria. One Escherichia coli (ST10), isolated from a Venus clam (Ruditapes philippinarum) harvested in the Mediterranean Sea (Italy), ...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Roschanski N, Guenther S, Vu TTT, Fischer J, Semmler T, Huehn S, Alter T, Roesler U Tags: Euro Surveill Source Type: research

Low interim influenza vaccine effectiveness, Australia, 1 May to 24 September 2017.
We present interim influenza vaccine effectiveness (VE) estimates from Australia. Adjusted VE was low overall at 33% (95% confidence interval (CI): 17 to 46), 50% (95% CI: 8 to 74) for A(H1)pdm09, 10% (95% CI: -16 to 31) for A(H3) and 57% (95% CI: 41 to 69) for influenza B. For A(H3), VE was poorer for those vaccinated in the current and prior seasons. PMID: 29090681 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Sullivan SG, Chilver MB, Carville KS, Deng YM, Grant KA, Higgins G, Komadina N, Leung VK, Minney-Smith CA, Teng D, Tran T, Stocks N, Fielding JE Tags: Euro Surveill Source Type: research

6thEurosurveillance scientific seminar 'One Health - we are in this together - Viral and bacterial diseases/conditions at the animal-human interface' at ESCAIDE 2017 in Stockholm.
PMID: 29067901 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Economic evaluation of HIV pre-exposure prophylaxis among men-who-have-sex-with-men in England in 2016.
Abstract Clinical effectiveness of pre-exposure prophylaxis (PrEP) for preventing HIV acquisition in men who have sex with men (MSM) at high HIV risk is established. A static decision analytical model was constructed to inform policy prioritisation in England around cost-effectiveness and budgetary impact of a PrEP programme covering 5,000 MSM during an initial high-risk period. National genitourinary medicine clinic surveillance data informed key HIV risk assumptions. Pragmatic large-scale implementation scenarios were explored. At 86% effectiveness, PrEP given to 5,000 MSM at 3.3 per 100 person-years annual HIV ...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Ong KJ, Desai S, Field N, Desai M, Nardone A, van Hoek AJ, Gill ON Tags: Euro Surveill Source Type: research

Measles outbreak linked to European B3 outbreaks, Wales, United Kingdom, 2017.
Abstract The United Kingdom achieved interrupted endemic measles transmission for 36 months in 2016. Despite this, ongoing challenges from sporadic measles cases typically imported from abroad remain. We summarise a B3 measles genotype outbreak in south-east Wales occurring between May and September 2017, linked with other European outbreaks, and lessons learnt. Seventeen confirmed cases and one probable case occurred principally in education and healthcare-settings. Six confirmed cases attended healthcare settings when infectious, without being isolated. PMID: 29067903 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Currie J, Davies L, McCarthy J, Perry M, Moore C, Cottrell S, Bowley M, Williams C, Shankar AG, Stiff R Tags: Euro Surveill Source Type: research

Options for affordable pre-exposure prophylaxis (PrEP) in national HIV prevention programmes in Europe.
PMID: 29067904 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Coleman R, Prins M Tags: Euro Surveill Source Type: research

Multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017.
We describe a multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Denmark, 2017. Whole genome sequencing of the strain GK124 identified MSLT ST1903, NG-MAST ST1614 and all relevant resistance determinants including similar penA resistance mutations previously described in ceftriaxone-resistant gonococcal strains. Although treatment with ceftriaxone 0.5 g plus azithromycin 2 g was successful, increased awareness of spread of gonococcal strains threatening the recommended dual therapy is crucial. PMID: 29067905 [PubMed - in pro...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Terkelsen D, Tolstrup J, Johnsen CH, Lund O, Larsen HK, Worning P, Unemo M, Westh H Tags: Euro Surveill Source Type: research

Surveillance of Zika virus infection in the EU/EEA, June 2015 to January 2017.
twork Abstract Surveillance of Zika virus (ZIKV) infection in the European Union/European Economic Area (EU/EEA) was implemented in 2016 in response to the large outbreak reported in the Americas in 2015 associated with an increased number of infants born with microcephaly. Between June 2015 and January 2017, 21 EU/EEA countries reported 2,133 confirmed cases of ZIKV infection, of whom 106 were pregnant women. Cases infected in the Caribbean constituted 71% of reported cases. Almost all cases (99%) were most probably infected by mosquito bite during travel outside continental Europe, while only 1% were transmitted...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Spiteri G, Sudre B, Septfons A, Beauté J, On Behalf Of The European Zika Surveillance Network Tags: Euro Surveill Source Type: research

Low 2016/17 season vaccine effectiveness against hospitalised influenza A(H3N2) among elderly: awareness warranted for 2017/18 season.
N, Lovric Z, Ferenczi A, I-Move Hospital Working Group, Moren A Abstract In a multicentre European hospital study we measured influenza vaccine effectiveness (IVE) against A(H3N2) in 2016/17. Adjusted IVE was 17% (95% confidence interval (CI): 1 to 31) overall; 25% (95% CI: 2 to 43) among 65-79-year-olds and 13% (95% CI: -15 to 30) among those ≥ 80 years. As the A(H3N2) vaccine component has not changed for 2017/18, physicians and public health experts should be aware that IVE could be low where A(H3N2) viruses predominate. PMID: 29043961 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Rondy M, Gherasim A, Casado I, Launay O, Rizzo C, Pitigoi D, Mickiene A, Marbus SD, Machado A, Syrjänen RK, Pem-Novose I, Horváth JK, Larrauri A, Castilla J, Vanhems P, Alfonsi V, Ivanciuc AE, Kuliese M, van Gageldonk-Lafeber R, Gomez V, Ikonen N, Lovri Tags: Euro Surveill Source Type: research

Usutu virus infections among blood donors, Austria, July and August 2017 - Raising awareness for diagnostic challenges.
Abstract Between July and August 2017, seven of 12,047 blood donations from eastern Austria, reacted positive to West Nile virus (WNV) in the cobas test (Roche). Follow-up investigations revealed Usutu virus (USUV) nucleic acid in six of these. Retrospective analyses of four blood donors diagnosed as WNV-infected in 2016 showed one USUV positive. Blood transfusion services and public health authorities in USUV-endemic areas should be aware of a possible increase of human USUV infections. PMID: 29043962 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Bakonyi T, Jungbauer C, Aberle SW, Kolodziejek J, Dimmel K, Stiasny K, Allerberger F, Nowotny N Tags: Euro Surveill Source Type: research

Call for papers for a special issue on advanced diagnostics to inform public health policy.
PMID: 29043963 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Accuracy of diagnosis criteria in patients with suspected diagnosis of sporadic Creutzfeldt-Jakob disease and detection of 14-3-3 protein, France, 1992 to 2009.
This study confirms the usefulness of the recent modification of diagnosis criteria by the addition of the results of CSF real-time quaking-induced conversion, a method based on prion seed-induced misfolding and aggregation of recombinant prion protein substrate that has proven to be a highly specific test for diagnosis of sporadic CJD. PMID: 29043964 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Peckeu L, Delasnerie-Lauprètre N, Brandel JP, Salomon D, Sazdovitch V, Laplanche JL, Duyckaerts C, Seilhean D, Haïk S, Hauw JJ Tags: Euro Surveill Source Type: research

Authors' reply: Geographic resolution of surveillance data and influenza prevention in large countries.
ource: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Authors' reply: Geographic resolution of surveillance data and influenza prevention in large countries. Tags: Euro Surveill Source Type: research

Infectious disease screening in asylum seekers: range, coverage and economic evaluation in Germany, 2015.
Abstract Screening asylum seekers for infectious diseases is widely performed, but economic evaluations of such are scarce. We performed a policy analysis and economic evaluation of such screening in Germany, and analysed the effect of screening policies on cost differences between federal states. Of the 16 states, screening was compulsory for tuberculosis (TB) in asylum seekers ≥ 16 years of age in all states as well as in children
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Bozorgmehr K, Wahedi K, Noest S, Szecsenyi J, Razum O Tags: Euro Surveill Source Type: research

Letter to the editor: Sampling bias should be minimised when analysing influenza transmission zones involving very large countries.
PMID: 29019316 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Shin GY, Manuel R Tags: Euro Surveill Source Type: research

PRECEPT: an evidence assessment framework for infectious disease epidemiology, prevention and control.
n O Abstract Decisions in public health should be based on the best available evidence, reviewed and appraised using a rigorous and transparent methodology. The Project on a Framework for Rating Evidence in Public Health (PRECEPT) defined a methodology for evaluating and grading evidence in infectious disease epidemiology, prevention and control that takes different domains and question types into consideration. The methodology rates evidence in four domains: disease burden, risk factors, diagnostics and intervention. The framework guiding it has four steps going from overarching questions to an evidence statement...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Harder T, Takla A, Eckmanns T, Ellis S, Forland F, James R, Meerpohl JJ, Morgan A, Rehfuess E, Schünemann H, Zuiderent-Jerak T, de Carvalho Gomes H, Wichmann O Tags: Euro Surveill Source Type: research

Addendum for Euro Surveill. 2017;22(8).
PMID: 29019318 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Increase in Legionnaires' disease cases associated with travel to Dubai among travellers from the United Kingdom, Sweden and the Netherlands, October 2016 to end August 2017.
Abstract Between 1 October 2016 and 31 August 2017, 51 Legionnaires' disease (LD) cases from the United Kingdom, Sweden and the Netherlands were identified with associated travel to Dubai. Cases did not all stay in the same accommodation, indicating that no single accommodation could be the source for all these infections. While local investigations continue into other potential sources, clinicians should remain alert to the possibility of LD among travellers returning from Dubai with respiratory illness. PMID: 28935023 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 21, 2017 Category: Infectious Diseases Authors: Dabrera G, Brandsema P, Lofdahl M, Naik F, Cameron R, McMenamin J, Pebody R, Phin N Tags: Euro Surveill Source Type: research

Note from the editors: Wave goodbye and say hello - Eurosurveillance to launch new website soon.
PMID: 28935024 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 21, 2017 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Burden of salmonellosis, campylobacteriosis and listeriosis: a time series analysis, Belgium, 2012 to 2020.
Abstract Salmonellosis, campylobacteriosis and listeriosis are food-borne diseases. We estimated and forecasted the number of cases of these three diseases in Belgium from 2012 to 2020, and calculated the corresponding number of disability-adjusted life years (DALYs). The salmonellosis time series was fitted with a Bai and Perron two-breakpoint model, while a dynamic linear model was used for campylobacteriosis and a Poisson autoregressive model for listeriosis. The average monthly number of cases of salmonellosis was 264 (standard deviation (SD): 86) in 2012 and predicted to be 212 (SD: 87) in 2020; campylobacter...
Source: Euro Surveill - September 21, 2017 Category: Infectious Diseases Authors: Maertens de Noordhout C, Devleesschauwer B, Haagsma JA, Havelaar AH, Bertrand S, Vandenberg O, Quoilin S, Brandt PT, Speybroeck N Tags: Euro Surveill Source Type: research

Ongoing outbreak with well over 4,000 measles cases in Italy from January to end August 2017 - what is making elimination so difficult?
We report an ongoing measles outbreak in Italy, with over 4,400 cases reported in 20 Regions from January to August 2017. Median age was 27 years, 88% of the cases were unvaccinated. The highest incidence was in infants below one year of age and 7% of cases occurred among healthcare workers. Three deaths occurred and two cases of encephalitis were reported. Wide immunity gaps and nosocomial transmission are major challenges to measles elimination in Italy. PMID: 28933342 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 14, 2017 Category: Infectious Diseases Authors: Filia A, Bella A, Del Manso M, Baggieri M, Magurano F, Rota MC Tags: Euro Surveill Source Type: research

The European Medical Corps: first Public Health Team mission and future perspectives.
Abstract The 2013-2016 Ebola epidemic in West Africa challenged traditional international mechanisms for public health team mobilisation to control outbreaks. Consequently, in February 2016, the European Union (EU) launched the European Medical Corps (EMC), a mechanism developed in collaboration with the World Health Organization (WHO) to rapidly deploy teams and equipment in response to public health emergencies inside and outside the EU. Public Health Teams (PHTs), a component of the EMC, consist of experts in communicable disease prevention and control from participating countries and the European Centre for Di...
Source: Euro Surveill - September 14, 2017 Category: Infectious Diseases Authors: Haussig JM, Severi E, Baum JH, Vanlerberghe V, Laiseca A, Defrance L, Brailescu C, Coulombier D, Jansa J Tags: Euro Surveill Source Type: research

First outbreak of Zika virus in the continental United States: a modelling analysis.
ler S Abstract Since 2015, Zika virus (ZIKV) has spread throughout Latin and Central America. This emerging infectious disease has been causing considerable public health concern because of severe neurological complications, especially in newborns after congenital infections. In July 2016, the first outbreak in the continental United States was identified in the Wynwood neighbourhood of Miami-Dade County, Florida. In this work, we investigated transmission dynamics using a mathematical model calibrated to observed data on mosquito abundance and symptomatic human infections. We found that, although ZIKV transmissio...
Source: Euro Surveill - September 14, 2017 Category: Infectious Diseases Authors: Marini G, Guzzetta G, Rosà R, Merler S Tags: Euro Surveill Source Type: research

Recurrent seasonal outbreak of an emerging serotype of Shiga toxin-producing Escherichia coli (STEC O55:H7 Stx2a) in the south west of England, July 2014 to September 2015.
Namara E, Hawker J, Balasegaram S Abstract The first documented British outbreak of Shiga toxin-producing Escherichia coli (STEC) O55:H7 began in the county of Dorset, England, in July 2014. Since then, there have been a total of 31 cases of which 13 presented with haemolytic uraemic syndrome (HUS). The outbreak strain had Shiga toxin (Stx) subtype 2a associated with an elevated risk of HUS. This strain had not previously been isolated from humans or animals in England. The only epidemiological link was living in or having close links to two areas in Dorset. Extensive investigations included testing of animals and...
Source: Euro Surveill - September 7, 2017 Category: Infectious Diseases Authors: McFarland N, Bundle N, Jenkins C, Godbole G, Mikhail A, Dallman T, O'Connor C, McCarthy N, O'Connell E, Treacy J, Dabke G, Mapstone J, Landy Y, Moore J, Partridge R, Jorgensen F, Willis C, Mook P, Rawlings C, Acornley R, Featherstone C, Gayle S, Edge J, M Tags: Euro Surveill Source Type: research

Addendum for Euro Surveill. 2017;22(35).
PMID: 28920572 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 7, 2017 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Preliminary findings indicate nosocomial transmission and Roma population as most affected group in ongoing measles B3 genotype outbreak in Bulgaria, March to August 2017.
Abstract From March to August 2017, 165 measles cases were reported from three regions in Bulgaria. The age range was 0-55 years and 66% of the cases were under 9 years. The Roma population was disproportionally affected (89% of cases), 41% cases were unvaccinated and in 24 cases there was nosocomial transmission mostly in paediatric departments. A child under 12 months of age died. Control measures have been taken and the investigation is still ongoing. PMID: 28920573 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 7, 2017 Category: Infectious Diseases Authors: Kurchatova A, Krumova S, Vladimirova N, Nikolaeva-Glomb L, Stoyanova A, Kantardjiev T, Gatcheva N Tags: Euro Surveill Source Type: research

Status, quality and specific needs of Zika virus (ZIKV) diagnostic capacity and capability in National Reference Laboratories for arboviruses in 30 EU/EEA countries, May 2016.
n C Abstract With international travel, Zika virus (ZIKV) is introduced to Europe regularly. A country's ability to robustly detect ZIKV introduction and local transmission is important to minimise the risk for a ZIKV outbreak. Therefore, sufficient expertise and diagnostic capacity and capability are required in European laboratories. To assess the capacity, quality, operational specifics (guidelines and algorithms), technical and interpretation issues and other possible difficulties that were related to ZIKV diagnostics in European countries, a questionnaire was conducted among national reference laboratories in...
Source: Euro Surveill - September 7, 2017 Category: Infectious Diseases Authors: Mögling R, Zeller H, Revez J, Koopmans M, ZIKV reference laboratory group, Reusken C Tags: Euro Surveill Source Type: research

Ongoing mumps outbreak in Israel, January to August 2017.
SR Abstract In Israel, 262 mumps cases were registered between 1 January and 28 August 2017 despite a vaccine coverage of ≥ 96%. The majority (56.5%) of cases were adolescents and young adults between 10 and 24 years of age. Nearly twice as many cases were reported in males than in females. Sequence information identified genotype G and suggested specific transmission chains in different religious communities, with the Muslim population in Jerusalem being most severely affected. PMID: 28877843 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 31, 2017 Category: Infectious Diseases Authors: Indenbaum V, Hübschen JM, Stein-Zamir C, Mendelson E, Sofer D, Hindiyeh M, Anis E, Abramson N, Haas EJ, Yosef Y, Dukhan L, Singer SR Tags: Euro Surveill Source Type: research

The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe?
get J Abstract We aimed to assess the epidemiology and spatiotemporal patterns of influenza in the World Health Organization (WHO) European Region and evaluate the validity of partitioning the Region into five influenza transmission zones (ITZs) as proposed by the WHO. We used the FluNet database and included over 650,000 influenza cases from 2000 to 2015. We analysed the data by country and season (from July to the following June). We calculated the median proportion of cases caused by each virus type in a season, compared the timing of the primary peak between countries and used a range of cluster analysis metho...
Source: Euro Surveill - August 31, 2017 Category: Infectious Diseases Authors: Caini S, Alonso WJ, Séblain CE, Schellevis F, Paget J Tags: Euro Surveill Source Type: research

Letter to the Editor: Surveillance of mcr-1 and mcr-2 genes in Carbapenem-resistant Klebsiella pneumoniae strains from an Italian Hospital.
PMID: 28877845 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 31, 2017 Category: Infectious Diseases Authors: Venditti C, Nisii C, D'Arezzo S, Vulcano A, Di Caro A Tags: Euro Surveill Source Type: research

Environmental surveillance during an outbreak of tularaemia in hares, the Netherlands, 2015.
en J Abstract Tularaemia, a disease caused by the bacterium Francisella tularensis, is a re-emerging zoonosis in the Netherlands. After sporadic human and hare cases occurred in the period 2011 to 2014, a cluster of F. tularensis-infected hares was recognised in a region in the north of the Netherlands from February to May 2015. No human cases were identified, including after active case finding. Presence of F. tularensis was investigated in potential reservoirs and transmission routes, including common voles, arthropod vectors and surface waters. F. tularensis was not detected in common voles, mosquito larvae or ...
Source: Euro Surveill - August 31, 2017 Category: Infectious Diseases Authors: Janse I, Maas M, Rijks JM, Koene M, van der Plaats RQ, Engelsma M, van der Tas P, Braks M, Stroo A, Notermans DW, de Vries MC, Reubsaet F, Fanoy E, Swaan C, Kik MJ, IJzer J, Jaarsma RI, van Wieren S, de Roda-Husman AM, van Passel M, Roest HJ, van der Gies Tags: Euro Surveill Source Type: research

Large measles outbreak introduced by asylum seekers and spread among the insufficiently vaccinated resident population, Berlin, October 2014 to August 2015.
Abstract The largest measles outbreak in Berlin since 2001 occurred from October 2014 to August 2015. Overall, 1,344 cases were ascertained, 86% (with available information) unvaccinated, including 146 (12%) asylum seekers. Median age was 17 years (interquartile range: 4-29 years), 26% were hospitalised and a 1-year-old child died. Measles virus genotyping uniformly revealed the variant 'D8-Rostov-Don' and descendants. The virus was likely introduced by and initially spread among asylum seekers before affecting Berlin's resident population. Among Berlin residents, the highest incidence was in children aged 
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Werber D, Hoffmann A, Santibanez S, Mankertz A, Sagebiel D Tags: Euro Surveill Source Type: research

Author's correction for Euro Surveill. 2017;22(32).
PMID: 28857044 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017.
We describe the dynamics of dengue virus (DENV) infection in a woman in her mid-30s who developed fever after returning from Sri Lanka to Italy in April 2017. Laboratory testing demonstrated detectable DENV-RNA in plasma, urine, saliva, vaginal secretion. Persistent shedding of DENV-RNA was demonstrated in vaginal secretion, and DENV-RNA was detectable in the pelleted fraction up to 18 days from symptom onset. These findings give new insights into DENV vaginal shedding and vertical transmission. PMID: 28857045 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Iannetta M, Lalle E, Musso M, Carletti F, Scorzolini L, D'Abramo A, Chinello P, Castilletti C, Ippolito G, Capobianchi MR, Nicastri E Tags: Euro Surveill Source Type: research

Erratum for Euro Surveill. 2017;22(31).
PMID: 28857046 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case-control study, Spain, 2013/14 and 2014/15.
PI12/02079 Abstract Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case-control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional log...
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Domínguez A, Soldevila N, Toledo D, Godoy P, Espejo E, Fernandez MA, Mayoral JM, Castilla J, Egurrola M, Tamames S, Astray J, Morales-Suárez-Varela M, Working Group of the Project PI12/02079 Tags: Euro Surveill Source Type: research

Ongoing large measles outbreak with nosocomial transmission in Milan, northern Italy, March-August 2017.
Abstract A large measles outbreak has been ongoing in Milan and surrounding areas. From 1 March to 30 June 2017, 203 measles cases were laboratory-confirmed (108 sporadic cases and 95 related to 47 clusters). Phylogenetic analysis revealed the co-circulation of two different genotypes, D8 and B3. Both genotypes caused nosocomial clusters in two hospitals. The rapid analysis of epidemiological and phylogenetic data allowed effective surveillance and tracking of transmission pathways. PMID: 28840825 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 17, 2017 Category: Infectious Diseases Authors: Amendola A, Bianchi S, Frati ER, Ciceri G, Faccini M, Senatore S, Colzani D, Lamberti A, Baggieri M, Cereda D, Gramegna M, Nicoletti L, Magurano F, Tanzi E Tags: Euro Surveill Source Type: research

A cluster of measles linked to an imported case, Finland, 2017.
n T, Sane J Abstract One imported and five secondary cases of measles were detected in Finland between June and August 2017. The measles sequences available for five laboratory-confirmed cases were identical and belonged to serotype D8. The large number of potentially exposed Finnish and foreign individuals called for close cooperation of national and international public health authorities and other stakeholders. Raising awareness among healthcare providers and ensuring universally high vaccination coverage is crucial to prevent future clusters and outbreaks. PMID: 28840826 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 17, 2017 Category: Infectious Diseases Authors: Seppälä E, Zöldi V, Vuorinen S, Murtopuro S, Elonsalo U, van Beek J, Haveri A, Kontio M, Savolainen-Kopra C, Puumalainen T, Sane J Tags: Euro Surveill Source Type: research

A nosocomial measles outbreak in Italy, February-April 2017.
We describe a nosocomial outbreak of measles that occurred in an Italian hospital during the first months of 2017, involving 35 persons and including healthcare workers, support personnel working in the hospital, visitors and community contacts. Late diagnosis of the first case, support personnel not being promptly recognised as hospital workers and diffusion of the infection in the emergency department had a major role in sustaining this outbreak. PMID: 28840827 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 17, 2017 Category: Infectious Diseases Authors: Porretta A, Quattrone F, Aquino F, Pieve G, Bruni B, Gemignani G, Vatteroni ML, Pistello M, Privitera GP, Lopalco PL Tags: Euro Surveill Source Type: research

Imported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection from Oman to Thailand, June 2015.
Abstract Thailand reported the first Middle East respiratory syndrome (MERS) case on 18 June 2015 (day 4) in an Omani patient with heart condition who was diagnosed with pneumonia on hospital admission on 15 June 2015 (day 1). Two false negative RT-PCR on upper respiratory tract samples on days 2 and 3 led to a 48-hour diagnosis delay and a decision to transfer the patient out of the negative pressure unit (NPU). Subsequent examination of sputum later on day 3 confirmed MERS coronavirus (MERS-CoV) infection. The patient was immediately moved back into the NPU and then transferred to Bamrasnaradura Infectious Disea...
Source: Euro Surveill - August 17, 2017 Category: Infectious Diseases Authors: Plipat T, Buathong R, Wacharapluesadee S, Siriarayapon P, Pittayawonganon C, Sangsajja C, Kaewpom T, Petcharat S, Ponpinit T, Jumpasri J, Joyjinda Y, Rodpan A, Ghai S, Jittmittraphap A, Khongwichit S, Smith DR, Corman VM, Drosten C, Hemachudha T Tags: Euro Surveill Source Type: research

Improving regional influenza surveillance through a combination of automated outbreak detection methods: the 2015/16 season in France.
oup Abstract The 2014/15 influenza epidemic caused a work overload for healthcare facilities in France. The French national public health agency announced the start of the epidemic - based on indicators aggregated at the national level - too late for many hospitals to prepare. It was therefore decided to improve the influenza alert procedure through (i) the introduction of a pre-epidemic alert level to better anticipate future outbreaks, (ii) the regionalisation of surveillance so that healthcare structures can be informed of the arrival of epidemics in their region, (iii) the standardised use of data sources and ...
Source: Euro Surveill - August 10, 2017 Category: Infectious Diseases Authors: Pelat C, Bonmarin I, Ruello M, Fouillet A, Caserio-Schönemann C, Levy-Bruhl D, Le Strat Y, Regional Influenza study group Tags: Euro Surveill Source Type: research

Evidence for more cost-effective surveillance options for bovine spongiform encephalopathy (BSE) and scrapie in Great Britain.
n J Abstract Transmissible spongiform encephalopathies (TSEs) are an important public health concern. Since the emergence of bovine spongiform encephalopathy (BSE) during the 1980s and its link with human Creutzfeldt-Jakob disease, active surveillance has been a key element of the European Union's TSE control strategy. Success of this strategy means that now, very few cases are detected compared with the number of animals tested. Refining surveillance strategies would enable resources to be redirected towards other public health priorities. Cost-effectiveness analysis was performed on several alternative strategie...
Source: Euro Surveill - August 10, 2017 Category: Infectious Diseases Authors: Wall BA, Arnold ME, Radia D, Gilbert W, Ortiz-Pelaez A, Stärk KD, Van Klink E, Guitian J Tags: Euro Surveill Source Type: research

Reoccurrence of botulinum neurotoxin subtype A3 inducing food-borne botulism, Slovakia, 2015.
ková I, Klement C, Dorner MB Abstract A case of food-borne botulism occurred in Slovakia in 2015. Clostridium botulinum type A was isolated from three nearly empty commercial hummus tubes. The product, which was sold in Slovakia and the Czech Republic, was withdrawn from the market and a warning was issued immediately through the European Commission's Rapid Alert System for Food and Feed (RASFF). Further investigation revealed the presence of botulinum neurotoxin (BoNT) subtype BoNT/A3, a very rare subtype implicated in only one previous outbreak (Loch Maree in Scotland, 1922). It is the most divergent subt...
Source: Euro Surveill - August 10, 2017 Category: Infectious Diseases Authors: Mad'arová L, Dorner BG, Schaade L, Donáth V, Avdičová M, Fatkulinová M, Strhársky J, Sedliačiková I, Klement C, Dorner MB Tags: Euro Surveill Source Type: research

Cyclosporiasis in travellers returning to the United Kingdom from Mexico in summer 2017: lessons from the recent past to inform the future.
Abstract During the summers of 2015 and 2016, the United Kingdom experienced large outbreaks of cyclosporiasis in travellers returning from Mexico. As the source of the outbreaks was not identified, there is the potential for a similar outbreak to occur in 2017; indeed 78 cases had already been reported as at 27 July 2017. Early communication and international collaboration is essential to provide a better understanding of the source and extent of this recurring situation. PMID: 28816651 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Marques DFP, Alexander CL, Chalmers RM, Elson R, Freedman J, Hawkins G, Lo J, Robinson G, Russell K, Smith-Palmer A, Kirkbride H Tags: Euro Surveill Source Type: research

Plasmid-encoded colistin resistance: mcr-one, two, three and counting.
PMID: 28797321 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Kluytmans J Tags: Euro Surveill Source Type: research

Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014.
AM Abstract A novel variant of the plasmid-borne colistin resistance gene mcr-3 was detected on an IncHI2 plasmid in an ST131 CTX-M-55-producing Escherichia coli isolate from a Danish patient with bloodstream infection in 2014. The discovery of novel plasmid-borne genes conferring resistance to colistin is of special interest since colistin has reemerged as an important drug in the treatment of infections with multidrug-resistant Gram-negative bacteria. PMID: 28797324 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Roer L, Hansen F, Stegger M, Sönksen UW, Hasman H, Hammerum AM Tags: Euro Surveill Source Type: research

Plasmid-borne colistin resistance gene mcr-3 in Salmonella isolates from human infections, Denmark, 2009-17.
This report describes one Salmonella isolate harbouring both mcr-1 and mcr-3. We also found nine other Salmonella isolates positive for the plasmid-borne colistin resistance gene, mcr-3. The strains were isolated from patients in Denmark between 2009 and 2017 and five of the patients had travelled to Asia. In addition to mcr-3, all strains were found positive for blaTEM-1, strA, strB, sul2 and tet(A) or tet(B), and most strains were positive for blaCTX-M-55 and qnrS. PMID: 28797325 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Litrup E, Kiil K, Hammerum AM, Roer L, Nielsen EM, Torpdahl M Tags: Euro Surveill Source Type: research

Co-occurrence of colistin-resistance genes mcr-1 and mcr-3 among multidrug-resistant Escherichia coli isolated from cattle, Spain, September 2015.
rte-Ruiz M, Domínguez L, Quesada A Abstract Colistin resistance genes mcr-3 and mcr-1 have been detected in an Escherichia coli isolate from cattle faeces in a Spanish slaughterhouse in 2015. The sequences of both genes hybridised to same plasmid band of ca 250 kb, although colistin resistance was non-mobilisable. The isolate was producing extended-spectrum beta-lactamases and belonged to serotype O9:H10 and sequence type ST533. Here we report an mcr-3 gene detected in Europe following earlier reports from Asia and the United States. PMID: 28797328 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Hernández M, Iglesias MR, Rodríguez-Lázaro D, Gallardo A, Quijada N, Miguela-Villoldo P, Campos MJ, Píriz S, López-Orozco G, de Frutos C, Sáez JL, Ugarte-Ruiz M, Domínguez L, Quesada A Tags: Euro Surveill Source Type: research

Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016.
Abstract A novel mcr colistin resistance gene was identified in a strain of Salmonella enterica, monophasic variant of serovar Typhimurium (4,5,12:i:- ), isolated from a pig at slaughter in Italy in 2013, and in Escherichia coli strains collected during routine diagnostic of post-weaning diarrhoea in pigs from Spain and Belgium in 2015 and 2016. Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Europe. PMID: 28797329 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Carattoli A, Villa L, Feudi C, Curcio L, Orsini S, Luppi A, Pezzotti G, Magistrali CF Tags: Euro Surveill Source Type: research

Evolving beta-lactamase epidemiology in Enterobacteriaceae from Italian nationwide surveillance, October 2013: KPC-carbapenemase spreading among outpatients.
This study investigated the presence of these resistance mechanisms in consecutive non-replicate isolates of Escherichia coli (n = 2,352), Klebsiella pneumoniae (n = 697), and Proteus mirabilis (n = 275) from an Italian nationwide cross-sectional survey carried out in October 2013. Overall, 15.3% of isolates were non-susceptible to extended-spectrum cephalosporins but susceptible to carbapenems (ESCR-carbaS), while 4.3% were also non-susceptible to carbapenems (ESCR-carbaR). ESCR-carbaS isolates were contributed by all three species, with higher proportions among isolates from inpa...
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Giani T, Antonelli A, Caltagirone M, Mauri C, Nicchi J, Arena F, Nucleo E, Bracco S, Pantosti A, AMCLI-CoSA survey participants, Luzzaro F, Pagani L, Rossolini GM Tags: Euro Surveill Source Type: research