Addendum for Euro Surveill. 2017;22(35).
PMID: 28920572 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 7, 2017 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Preliminary findings indicate nosocomial transmission and Roma population as most affected group in ongoing measles B3 genotype outbreak in Bulgaria, March to August 2017.
Abstract From March to August 2017, 165 measles cases were reported from three regions in Bulgaria. The age range was 0-55 years and 66% of the cases were under 9 years. The Roma population was disproportionally affected (89% of cases), 41% cases were unvaccinated and in 24 cases there was nosocomial transmission mostly in paediatric departments. A child under 12 months of age died. Control measures have been taken and the investigation is still ongoing. PMID: 28920573 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 7, 2017 Category: Infectious Diseases Authors: Kurchatova A, Krumova S, Vladimirova N, Nikolaeva-Glomb L, Stoyanova A, Kantardjiev T, Gatcheva N Tags: Euro Surveill Source Type: research

Status, quality and specific needs of Zika virus (ZIKV) diagnostic capacity and capability in National Reference Laboratories for arboviruses in 30 EU/EEA countries, May 2016.
n C Abstract With international travel, Zika virus (ZIKV) is introduced to Europe regularly. A country's ability to robustly detect ZIKV introduction and local transmission is important to minimise the risk for a ZIKV outbreak. Therefore, sufficient expertise and diagnostic capacity and capability are required in European laboratories. To assess the capacity, quality, operational specifics (guidelines and algorithms), technical and interpretation issues and other possible difficulties that were related to ZIKV diagnostics in European countries, a questionnaire was conducted among national reference laboratories in...
Source: Euro Surveill - September 7, 2017 Category: Infectious Diseases Authors: Mögling R, Zeller H, Revez J, Koopmans M, ZIKV reference laboratory group, Reusken C Tags: Euro Surveill Source Type: research

Ongoing mumps outbreak in Israel, January to August 2017.
SR Abstract In Israel, 262 mumps cases were registered between 1 January and 28 August 2017 despite a vaccine coverage of ≥ 96%. The majority (56.5%) of cases were adolescents and young adults between 10 and 24 years of age. Nearly twice as many cases were reported in males than in females. Sequence information identified genotype G and suggested specific transmission chains in different religious communities, with the Muslim population in Jerusalem being most severely affected. PMID: 28877843 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 31, 2017 Category: Infectious Diseases Authors: Indenbaum V, Hübschen JM, Stein-Zamir C, Mendelson E, Sofer D, Hindiyeh M, Anis E, Abramson N, Haas EJ, Yosef Y, Dukhan L, Singer SR Tags: Euro Surveill Source Type: research

The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe?
get J Abstract We aimed to assess the epidemiology and spatiotemporal patterns of influenza in the World Health Organization (WHO) European Region and evaluate the validity of partitioning the Region into five influenza transmission zones (ITZs) as proposed by the WHO. We used the FluNet database and included over 650,000 influenza cases from 2000 to 2015. We analysed the data by country and season (from July to the following June). We calculated the median proportion of cases caused by each virus type in a season, compared the timing of the primary peak between countries and used a range of cluster analysis metho...
Source: Euro Surveill - August 31, 2017 Category: Infectious Diseases Authors: Caini S, Alonso WJ, Séblain CE, Schellevis F, Paget J Tags: Euro Surveill Source Type: research

Letter to the Editor: Surveillance of mcr-1 and mcr-2 genes in Carbapenem-resistant Klebsiella pneumoniae strains from an Italian Hospital.
PMID: 28877845 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 31, 2017 Category: Infectious Diseases Authors: Venditti C, Nisii C, D'Arezzo S, Vulcano A, Di Caro A Tags: Euro Surveill Source Type: research

Environmental surveillance during an outbreak of tularaemia in hares, the Netherlands, 2015.
en J Abstract Tularaemia, a disease caused by the bacterium Francisella tularensis, is a re-emerging zoonosis in the Netherlands. After sporadic human and hare cases occurred in the period 2011 to 2014, a cluster of F. tularensis-infected hares was recognised in a region in the north of the Netherlands from February to May 2015. No human cases were identified, including after active case finding. Presence of F. tularensis was investigated in potential reservoirs and transmission routes, including common voles, arthropod vectors and surface waters. F. tularensis was not detected in common voles, mosquito larvae or ...
Source: Euro Surveill - August 31, 2017 Category: Infectious Diseases Authors: Janse I, Maas M, Rijks JM, Koene M, van der Plaats RQ, Engelsma M, van der Tas P, Braks M, Stroo A, Notermans DW, de Vries MC, Reubsaet F, Fanoy E, Swaan C, Kik MJ, IJzer J, Jaarsma RI, van Wieren S, de Roda-Husman AM, van Passel M, Roest HJ, van der Gies Tags: Euro Surveill Source Type: research

Large measles outbreak introduced by asylum seekers and spread among the insufficiently vaccinated resident population, Berlin, October 2014 to August 2015.
Abstract The largest measles outbreak in Berlin since 2001 occurred from October 2014 to August 2015. Overall, 1,344 cases were ascertained, 86% (with available information) unvaccinated, including 146 (12%) asylum seekers. Median age was 17 years (interquartile range: 4-29 years), 26% were hospitalised and a 1-year-old child died. Measles virus genotyping uniformly revealed the variant 'D8-Rostov-Don' and descendants. The virus was likely introduced by and initially spread among asylum seekers before affecting Berlin's resident population. Among Berlin residents, the highest incidence was in children aged 
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Werber D, Hoffmann A, Santibanez S, Mankertz A, Sagebiel D Tags: Euro Surveill Source Type: research

Author's correction for Euro Surveill. 2017;22(32).
PMID: 28857044 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Persistent detection of dengue virus RNA in vaginal secretion of a woman returning from Sri Lanka to Italy, April 2017.
We describe the dynamics of dengue virus (DENV) infection in a woman in her mid-30s who developed fever after returning from Sri Lanka to Italy in April 2017. Laboratory testing demonstrated detectable DENV-RNA in plasma, urine, saliva, vaginal secretion. Persistent shedding of DENV-RNA was demonstrated in vaginal secretion, and DENV-RNA was detectable in the pelleted fraction up to 18 days from symptom onset. These findings give new insights into DENV vaginal shedding and vertical transmission. PMID: 28857045 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Iannetta M, Lalle E, Musso M, Carletti F, Scorzolini L, D'Abramo A, Chinello P, Castilletti C, Ippolito G, Capobianchi MR, Nicastri E Tags: Euro Surveill Source Type: research

Erratum for Euro Surveill. 2017;22(31).
PMID: 28857046 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case-control study, Spain, 2013/14 and 2014/15.
PI12/02079 Abstract Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case-control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional log...
Source: Euro Surveill - August 24, 2017 Category: Infectious Diseases Authors: Domínguez A, Soldevila N, Toledo D, Godoy P, Espejo E, Fernandez MA, Mayoral JM, Castilla J, Egurrola M, Tamames S, Astray J, Morales-Suárez-Varela M, Working Group of the Project PI12/02079 Tags: Euro Surveill Source Type: research

Ongoing large measles outbreak with nosocomial transmission in Milan, northern Italy, March-August 2017.
Abstract A large measles outbreak has been ongoing in Milan and surrounding areas. From 1 March to 30 June 2017, 203 measles cases were laboratory-confirmed (108 sporadic cases and 95 related to 47 clusters). Phylogenetic analysis revealed the co-circulation of two different genotypes, D8 and B3. Both genotypes caused nosocomial clusters in two hospitals. The rapid analysis of epidemiological and phylogenetic data allowed effective surveillance and tracking of transmission pathways. PMID: 28840825 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 17, 2017 Category: Infectious Diseases Authors: Amendola A, Bianchi S, Frati ER, Ciceri G, Faccini M, Senatore S, Colzani D, Lamberti A, Baggieri M, Cereda D, Gramegna M, Nicoletti L, Magurano F, Tanzi E Tags: Euro Surveill Source Type: research

A cluster of measles linked to an imported case, Finland, 2017.
n T, Sane J Abstract One imported and five secondary cases of measles were detected in Finland between June and August 2017. The measles sequences available for five laboratory-confirmed cases were identical and belonged to serotype D8. The large number of potentially exposed Finnish and foreign individuals called for close cooperation of national and international public health authorities and other stakeholders. Raising awareness among healthcare providers and ensuring universally high vaccination coverage is crucial to prevent future clusters and outbreaks. PMID: 28840826 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 17, 2017 Category: Infectious Diseases Authors: Seppälä E, Zöldi V, Vuorinen S, Murtopuro S, Elonsalo U, van Beek J, Haveri A, Kontio M, Savolainen-Kopra C, Puumalainen T, Sane J Tags: Euro Surveill Source Type: research

A nosocomial measles outbreak in Italy, February-April 2017.
We describe a nosocomial outbreak of measles that occurred in an Italian hospital during the first months of 2017, involving 35 persons and including healthcare workers, support personnel working in the hospital, visitors and community contacts. Late diagnosis of the first case, support personnel not being promptly recognised as hospital workers and diffusion of the infection in the emergency department had a major role in sustaining this outbreak. PMID: 28840827 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 17, 2017 Category: Infectious Diseases Authors: Porretta A, Quattrone F, Aquino F, Pieve G, Bruni B, Gemignani G, Vatteroni ML, Pistello M, Privitera GP, Lopalco PL Tags: Euro Surveill Source Type: research

Imported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection from Oman to Thailand, June 2015.
Abstract Thailand reported the first Middle East respiratory syndrome (MERS) case on 18 June 2015 (day 4) in an Omani patient with heart condition who was diagnosed with pneumonia on hospital admission on 15 June 2015 (day 1). Two false negative RT-PCR on upper respiratory tract samples on days 2 and 3 led to a 48-hour diagnosis delay and a decision to transfer the patient out of the negative pressure unit (NPU). Subsequent examination of sputum later on day 3 confirmed MERS coronavirus (MERS-CoV) infection. The patient was immediately moved back into the NPU and then transferred to Bamrasnaradura Infectious Disea...
Source: Euro Surveill - August 17, 2017 Category: Infectious Diseases Authors: Plipat T, Buathong R, Wacharapluesadee S, Siriarayapon P, Pittayawonganon C, Sangsajja C, Kaewpom T, Petcharat S, Ponpinit T, Jumpasri J, Joyjinda Y, Rodpan A, Ghai S, Jittmittraphap A, Khongwichit S, Smith DR, Corman VM, Drosten C, Hemachudha T Tags: Euro Surveill Source Type: research

Improving regional influenza surveillance through a combination of automated outbreak detection methods: the 2015/16 season in France.
oup Abstract The 2014/15 influenza epidemic caused a work overload for healthcare facilities in France. The French national public health agency announced the start of the epidemic - based on indicators aggregated at the national level - too late for many hospitals to prepare. It was therefore decided to improve the influenza alert procedure through (i) the introduction of a pre-epidemic alert level to better anticipate future outbreaks, (ii) the regionalisation of surveillance so that healthcare structures can be informed of the arrival of epidemics in their region, (iii) the standardised use of data sources and ...
Source: Euro Surveill - August 10, 2017 Category: Infectious Diseases Authors: Pelat C, Bonmarin I, Ruello M, Fouillet A, Caserio-Schönemann C, Levy-Bruhl D, Le Strat Y, Regional Influenza study group Tags: Euro Surveill Source Type: research

Evidence for more cost-effective surveillance options for bovine spongiform encephalopathy (BSE) and scrapie in Great Britain.
n J Abstract Transmissible spongiform encephalopathies (TSEs) are an important public health concern. Since the emergence of bovine spongiform encephalopathy (BSE) during the 1980s and its link with human Creutzfeldt-Jakob disease, active surveillance has been a key element of the European Union's TSE control strategy. Success of this strategy means that now, very few cases are detected compared with the number of animals tested. Refining surveillance strategies would enable resources to be redirected towards other public health priorities. Cost-effectiveness analysis was performed on several alternative strategie...
Source: Euro Surveill - August 10, 2017 Category: Infectious Diseases Authors: Wall BA, Arnold ME, Radia D, Gilbert W, Ortiz-Pelaez A, Stärk KD, Van Klink E, Guitian J Tags: Euro Surveill Source Type: research

Reoccurrence of botulinum neurotoxin subtype A3 inducing food-borne botulism, Slovakia, 2015.
ková I, Klement C, Dorner MB Abstract A case of food-borne botulism occurred in Slovakia in 2015. Clostridium botulinum type A was isolated from three nearly empty commercial hummus tubes. The product, which was sold in Slovakia and the Czech Republic, was withdrawn from the market and a warning was issued immediately through the European Commission's Rapid Alert System for Food and Feed (RASFF). Further investigation revealed the presence of botulinum neurotoxin (BoNT) subtype BoNT/A3, a very rare subtype implicated in only one previous outbreak (Loch Maree in Scotland, 1922). It is the most divergent subt...
Source: Euro Surveill - August 10, 2017 Category: Infectious Diseases Authors: Mad'arová L, Dorner BG, Schaade L, Donáth V, Avdičová M, Fatkulinová M, Strhársky J, Sedliačiková I, Klement C, Dorner MB Tags: Euro Surveill Source Type: research

Cyclosporiasis in travellers returning to the United Kingdom from Mexico in summer 2017: lessons from the recent past to inform the future.
Abstract During the summers of 2015 and 2016, the United Kingdom experienced large outbreaks of cyclosporiasis in travellers returning from Mexico. As the source of the outbreaks was not identified, there is the potential for a similar outbreak to occur in 2017; indeed 78 cases had already been reported as at 27 July 2017. Early communication and international collaboration is essential to provide a better understanding of the source and extent of this recurring situation. PMID: 28816651 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Marques DFP, Alexander CL, Chalmers RM, Elson R, Freedman J, Hawkins G, Lo J, Robinson G, Russell K, Smith-Palmer A, Kirkbride H Tags: Euro Surveill Source Type: research

Plasmid-encoded colistin resistance: mcr-one, two, three and counting.
PMID: 28797321 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Kluytmans J Tags: Euro Surveill Source Type: research

Novel mcr-3 variant, encoding mobile colistin resistance, in an ST131 Escherichia coli isolate from bloodstream infection, Denmark, 2014.
AM Abstract A novel variant of the plasmid-borne colistin resistance gene mcr-3 was detected on an IncHI2 plasmid in an ST131 CTX-M-55-producing Escherichia coli isolate from a Danish patient with bloodstream infection in 2014. The discovery of novel plasmid-borne genes conferring resistance to colistin is of special interest since colistin has reemerged as an important drug in the treatment of infections with multidrug-resistant Gram-negative bacteria. PMID: 28797324 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Roer L, Hansen F, Stegger M, Sönksen UW, Hasman H, Hammerum AM Tags: Euro Surveill Source Type: research

Plasmid-borne colistin resistance gene mcr-3 in Salmonella isolates from human infections, Denmark, 2009-17.
This report describes one Salmonella isolate harbouring both mcr-1 and mcr-3. We also found nine other Salmonella isolates positive for the plasmid-borne colistin resistance gene, mcr-3. The strains were isolated from patients in Denmark between 2009 and 2017 and five of the patients had travelled to Asia. In addition to mcr-3, all strains were found positive for blaTEM-1, strA, strB, sul2 and tet(A) or tet(B), and most strains were positive for blaCTX-M-55 and qnrS. PMID: 28797325 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Litrup E, Kiil K, Hammerum AM, Roer L, Nielsen EM, Torpdahl M Tags: Euro Surveill Source Type: research

Co-occurrence of colistin-resistance genes mcr-1 and mcr-3 among multidrug-resistant Escherichia coli isolated from cattle, Spain, September 2015.
rte-Ruiz M, Domínguez L, Quesada A Abstract Colistin resistance genes mcr-3 and mcr-1 have been detected in an Escherichia coli isolate from cattle faeces in a Spanish slaughterhouse in 2015. The sequences of both genes hybridised to same plasmid band of ca 250 kb, although colistin resistance was non-mobilisable. The isolate was producing extended-spectrum beta-lactamases and belonged to serotype O9:H10 and sequence type ST533. Here we report an mcr-3 gene detected in Europe following earlier reports from Asia and the United States. PMID: 28797328 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Hernández M, Iglesias MR, Rodríguez-Lázaro D, Gallardo A, Quijada N, Miguela-Villoldo P, Campos MJ, Píriz S, López-Orozco G, de Frutos C, Sáez JL, Ugarte-Ruiz M, Domínguez L, Quesada A Tags: Euro Surveill Source Type: research

Novel plasmid-mediated colistin resistance mcr-4 gene in Salmonella and Escherichia coli, Italy 2013, Spain and Belgium, 2015 to 2016.
Abstract A novel mcr colistin resistance gene was identified in a strain of Salmonella enterica, monophasic variant of serovar Typhimurium (4,5,12:i:- ), isolated from a pig at slaughter in Italy in 2013, and in Escherichia coli strains collected during routine diagnostic of post-weaning diarrhoea in pigs from Spain and Belgium in 2015 and 2016. Immediate implementation of mcr-screening including this novel gene variant is required for Salmonella and E. coli from humans and food-producing animals in Europe. PMID: 28797329 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Carattoli A, Villa L, Feudi C, Curcio L, Orsini S, Luppi A, Pezzotti G, Magistrali CF Tags: Euro Surveill Source Type: research

Evolving beta-lactamase epidemiology in Enterobacteriaceae from Italian nationwide surveillance, October 2013: KPC-carbapenemase spreading among outpatients.
This study investigated the presence of these resistance mechanisms in consecutive non-replicate isolates of Escherichia coli (n = 2,352), Klebsiella pneumoniae (n = 697), and Proteus mirabilis (n = 275) from an Italian nationwide cross-sectional survey carried out in October 2013. Overall, 15.3% of isolates were non-susceptible to extended-spectrum cephalosporins but susceptible to carbapenems (ESCR-carbaS), while 4.3% were also non-susceptible to carbapenems (ESCR-carbaR). ESCR-carbaS isolates were contributed by all three species, with higher proportions among isolates from inpa...
Source: Euro Surveill - August 3, 2017 Category: Infectious Diseases Authors: Giani T, Antonelli A, Caltagirone M, Mauri C, Nicchi J, Arena F, Nucleo E, Bracco S, Pantosti A, AMCLI-CoSA survey participants, Luzzaro F, Pagani L, Rossolini GM Tags: Euro Surveill Source Type: research

2015/16 seasonal vaccine effectiveness against hospitalisation with influenza A(H1N1)pdm09 and B among elderly people in Europe: results from the I-MOVE+ project.
N, Mickiene A, Gomez V, Kurečić Filipović S, Ferenczi A, Korcinska MR, van Gageldonk-Lafeber R, I-MOVE+ hospital working group, Valenciano M Abstract We conducted a multicentre test-negative case-control study in 27 hospitals of 11 European countries to measure 2015/16 influenza vaccine effectiveness (IVE) against hospitalised influenza A(H1N1)pdm09 and B among people aged ≥ 65 years. Patients swabbed within 7 days after onset of symptoms compatible with severe acute respiratory infection were included. Information on demographics, vaccination and underlying conditions was collected. Us...
Source: Euro Surveill - July 27, 2017 Category: Infectious Diseases Authors: Rondy M, Larrauri A, Casado I, Alfonsi V, Pitigoi D, Launay O, Syrjänen RK, Gefenaite G, Machado A, Vučina VV, Horváth JK, Paradowska-Stankiewicz I, Marbus SD, Gherasim A, Díaz-González JA, Rizzo C, Ivanciuc AE, Galtier F, Ikonen N, Mickiene A, Gomez Tags: Euro Surveill Source Type: research

Hepatitis C virus seroprevalence and prevalence of chronic infection in the adult population in Ireland: a study of residual sera, April 2014 to February 2016.
Abstract Robust data on hepatitis C virus (HCV) population prevalence are essential to inform national HCV services. In 2016, we undertook a survey to estimate HCV prevalence among the adult population in Ireland. We used anonymised residual sera available at the National Virus Reference Laboratory. We selected a random sample comprising persons ≥ 18 years with probability proportional to the general population age-sex distribution. Anti-HCV and HCV Ag were determined using the Architect anti-HCV and HCV Ag assays. Fifty-three of 3,795 specimens were seropositive (age-sex-area weighted seroprevale...
Source: Euro Surveill - July 27, 2017 Category: Infectious Diseases Authors: Garvey P, O'Grady B, Franzoni G, Bolger M, Irwin Crosby K, Connell J, Burke D, De Gascun C, Thornton L Tags: Euro Surveill Source Type: research

Severe liver disease related to chronic hepatitis C virus infection in treatment-naive patients: epidemiological characteristics and associated factors at first expert centre visit, France, 2000 to 2007 and 2010 to 2014.
Abstract Given recent profound improvements in the effectiveness of antiviral treatment for chronic Hepatitis C virus (HCV) infection, we aimed to describe the characteristics of patients referred to hepatology expert centres in France from 2000 to 2007 and from 2010 to 2014, and to identify factors associated with severe liver disease at their first visit for evaluation. We analysed data from two sources covering all of France: the former hepatitis C surveillance network, which included patients between 2000 and 2007, and the ANRS CO22 HEPATHER multi-centre cohort, which included patients between 2012 and 2014. S...
Source: Euro Surveill - July 27, 2017 Category: Infectious Diseases Authors: Sanna A, Le Strat Y, Roudot-Thoraval F, Deuffic Burban S, Carrieri P, Delarocque-Astagneau E, Larsen C Tags: Euro Surveill Source Type: research

Outbreak of intestinal amoebiasis among men who have sex with men, Barcelona (Spain), October 2016 and January 2017.
Barberá MJ Abstract Entamoeba histolytica has been recently recognised as an emerging sexually transmissible pathogen in men who have sex with men (MSM), causing sporadic outbreaks in countries where it is not endemic. Here we report two closed clusters of invasive amoebiasis occurring in Barcelona, Spain, in October 2016 (four cases) and in January 2017 (four cases). PMID: 28797327 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - July 27, 2017 Category: Infectious Diseases Authors: Escolà-Vergé L, Arando M, Vall M, Rovira R, Espasa M, Sulleiro E, Armengol P, Zarzuela F, Barberá MJ Tags: Euro Surveill Source Type: research

Human myiasis caused by the reindeer warble fly, Hypoderma tarandi, case series from Norway, 2011 to 2016.
We report a series of 39 human myiasis cases caused by H. tarandi in Norway from 2011 to 2016. Thirty-two were residents of Finnmark, the northernmost county of Norway, one a visitor to Finnmark, and six lived in other counties of Norway where reindeer live. Clinical manifestations involved migratory dermal swellings of the face and head, enlargement of regional lymph nodes, and periorbital oedema, with or without eosinophilia. Most cases of human myiasis are seen in tropical and subtropical countries, and in tourists returning from such areas. Our findings demonstrate that myiasis caused by H. tarandi is more common than ...
Source: Euro Surveill - July 20, 2017 Category: Infectious Diseases Authors: Landehag J, Skogen A, Åsbakk K, Kan B Tags: Euro Surveill Source Type: research

Are pertussis cases reported too late for public health interventions? Retrospective analysis of cases in London and South East England, 2010 to 2015.
Abstract In the United Kingdom, pertussis guidance recommends prophylaxis for household contacts within 21 days of case symptom onset if the household includes a vulnerable contact. The aim of our study was to identify characteristics associated with cases reported late for public health action. We reviewed the epidemiology of cases reported in London and South East England for the period 2010 to 2015. We characterised risk factors associated with late reporting of cases and described public health actions taken on timely reported cases. From 2010 to 2015, 9,163 cases of pertussis were reported to health protectio...
Source: Euro Surveill - July 20, 2017 Category: Infectious Diseases Authors: Crabbe H, Saavedra-Campos M, Verlander NQ, Leonard A, Morris J, Wright A, Balasegaram S Tags: Euro Surveill Source Type: research

Ongoing hepatitis A among men who have sex with men (MSM) linked to outbreaks in Europe in Tel Aviv area, Israel, December 2016 - June 2017.
Abstract Between December 2016 and June 2017, 19 Hepatitis A virus (HAV)-positive cases, 17 of which were among men who have sex with men (MSM) were identified in the Tel Aviv area. Seven of the 15 sewage samples collected between January and June 2017 were also HAV-positive. All sequences clustered with two of the three strains identified in the current European HAV outbreak. We demonstrate that despite an efficient vaccination programme, HAV can still be transmitted to an unvaccinated high-risk population. PMID: 28749336 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - July 20, 2017 Category: Infectious Diseases Authors: Gozlan Y, Bar-Or I, Rakovsky A, Savion M, Amitai Z, Sheffer R, Ceder N, Anis E, Grotto I, Mendelson E, Mor O Tags: Euro Surveill Source Type: research

Pertussis surveillance and control: exploring variations and delays in testing, laboratory diagnostics and public health service notifications, the Netherlands, 2010 to 2013.
Abstract Pertussis is most severe among unvaccinated infants (
Source: Euro Surveill - July 13, 2017 Category: Infectious Diseases Authors: Heil J, Ter Waarbeek HLG, Hoebe CJPA, Jacobs PHA, van Dam DW, Trienekens TAM, Cals JWL, van Loo IHM, Dukers-Muijrers NHTM Tags: Euro Surveill Source Type: research

A cluster of invasive meningococcal disease (IMD) caused by Neisseria meningitidis serogroup W among university students, France, February to May 2017.
oya I Abstract Between February and May 2017, two cases of invasive meningococcal disease caused by a new, rapidly expanding serogroup W meningococci variant were reported among students of an international university in Paris. Bacteriological investigations showed that isolates shared identical genotypic formula (W:P1.5,2:F1-1:cc11) and belonged to the South American/UK lineage. A vaccination campaign was organised that aimed at preventing new cases linked to potential persistence of the circulation of the bacteria in the students. PMID: 28749333 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - July 13, 2017 Category: Infectious Diseases Authors: Bassi C, Taha MK, Merle C, Hong E, Lévy-Bruhl D, Barret AS, Mounchetrou Njoya I Tags: Euro Surveill Source Type: research

Evaluation of a widely used culture-based method for detection of livestock-associated meticillin-resistant Staphylococcus aureus (MRSA), Denmark and Norway, 2014 to 2016.
en Ø Abstract We evaluated a widely used culture-based method for detection of livestock-associated meticillin-resistant Staphylococcus aureus (LA-MRSA) in samples collected from pigs and the environment inside pig stables in Denmark and Norway. Selective enrichment in tryptic soy broth containing cefoxitin and aztreonam led to a high ratio of false-negative results (26%; 57/221). On this basis, we recommend reconsidering the use of selective enrichment for detection of LA-MRSA in animal and environmental samples. PMID: 28749335 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - July 13, 2017 Category: Infectious Diseases Authors: Larsen J, Sunde M, Islam MZ, Urdahl AM, Barstad AS, Larsen AR, Grøntvedt CA, Angen Ø Tags: Euro Surveill Source Type: research

International risk of yellow fever spread from the ongoing outbreak in Brazil, December 2016 to May 2017.
Abstract States in south-eastern Brazil were recently affected by the largest Yellow Fever (YF) outbreak seen in a decade in Latin America. Here we provide a quantitative assessment of the risk of travel-related international spread of YF indicating that the United States, Argentina, Uruguay, Spain, Italy and Germany may have received at least one travel-related YF case capable of seeding local transmission. Mitigating the risk of imported YF cases seeding local transmission requires heightened surveillance globally. PMID: 28749337 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - July 13, 2017 Category: Infectious Diseases Authors: Dorigatti I, Hamlet A, Aguas R, Cattarino L, Cori A, Donnelly CA, Garske T, Imai N, Ferguson NM Tags: Euro Surveill Source Type: research

Legionnaires' disease in Europe, 2011 to 2015.
e Network Abstract Under the coordination of the European Centre for Disease Prevention and Control (ECDC), the European Legionnaires' disease Surveillance Network (ELDSNet) conducts surveillance of Legionnaires' disease (LD) in Europe. Between 2011 and 2015, 29 countries reported 30,532 LD cases to ECDC (28,188 (92.3%) confirmed and 2,344 (7.7%) probable). Four countries (France, Germany, Italy and Spain) accounted for 70.3% of all reported cases, although their combined populations represented only 49.9% of the study population. The age-standardised rate of all cases increased from 0.97 cases/100,000 population ...
Source: Euro Surveill - July 6, 2017 Category: Infectious Diseases Authors: Beauté J, European Legionnaires’ Disease Surveillance Network Tags: Euro Surveill Source Type: research

Surveillance perspective on Lyme borreliosis across the European Union and European Economic Area.
tel W Abstract Lyme borreliosis (LB) is the most prevalent tick-borne disease in Europe. Erythema migrans (EM), an early, localised skin rash, is its most common presentation. Dissemination of the bacteria can lead to more severe manifestations including skin, neurological, cardiac, musculoskeletal and ocular manifestations. Comparison of LB incidence rates in the European Union (EU)/European Economic Area (EEA) and Balkan countries are difficult in the absence of standardised surveillance and reporting procedures. We explored six surveillance scenarios for LB surveillance in the EU/EEA, based on the following key...
Source: Euro Surveill - July 6, 2017 Category: Infectious Diseases Authors: van den Wijngaard CC, Hofhuis A, Simões M, Rood E, van Pelt W, Zeller H, Van Bortel W Tags: Euro Surveill Source Type: research

Letter to the editor: Trends in tuberculosis notification rates by country of origin in the metropolitan area of Rome, 2010 to 2015.
i E, Puro V PMID: 28703099 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - July 6, 2017 Category: Infectious Diseases Authors: Sañé Schepisi M, Scognamiglio P, D'Amato M, Girardi E, Puro V Tags: Euro Surveill Source Type: research

Epidemiology of human infections with highly pathogenic avian influenza A(H7N9) virus in Guangdong, 2016 to 2017.
We describe the epidemiology of highly pathogenic avian influenza (HPAI) A(H7N9) based on poultry market environmental surveillance and laboratory-confirmed human cases (n = 9) in Guangdong, China. We also compare the epidemiology between human cases of high- and low-pathogenic avian influenza A(H7N9) (n = 51) in Guangdong. Case fatality and severity were similar. Touching sick or dead poultry was the most important risk factor for HPAI A(H7N9) infections and should be highlighted for the control of future influenza A(H7N9) epidemics. PMID: 28703705 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - July 6, 2017 Category: Infectious Diseases Authors: Kang M, Lau EHY, Guan W, Yang Y, Song T, Cowling BJ, Wu J, Peiris M, He J, Mok CKP Tags: Euro Surveill Source Type: research

Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016.
Abstract In Europe, enterovirus A71 (EV-A71) has primarily been associated with sporadic cases of neurological disease. The recent emergence of new genotypes and larger outbreaks with severely ill patients demonstrates a potential for the spread of new, highly pathogenic EV-A71 strains. Detection and characterisation of these new emerging EV variants is challenging as standard EV assays may not be adequate, necessitating the use of whole genome analysis. PMID: 28681718 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 29, 2017 Category: Infectious Diseases Authors: Midgley SE, Nielsen AG, Trebbien R, Poulsen MW, Andersen PH, Fischer TK Tags: Euro Surveill Source Type: research

An outbreak of dengue virus (DENV) type 2 Cosmopolitan genotype in Israeli travellers returning from the Seychelles, April 2017.
This report further demonstrates the role of travellers as sentinels for arboviral infections, especially in countries with limited diagnostic capabilities. PMID: 28681719 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 29, 2017 Category: Infectious Diseases Authors: Lustig Y, Wolf D, Halutz O, Schwartz E Tags: Euro Surveill Source Type: research

Dot map cartograms for detection of infectious disease outbreaks: an application to Q fever, the Netherlands and pertussis, Germany.
nga J Abstract Geographical mapping of infectious diseases is an important tool for detecting and characterising outbreaks. Two common mapping methods, dot maps and incidence maps, have important shortcomings. The former does not represent population density and can compromise case privacy, and the latter relies on pre-defined administrative boundaries. We propose a method that overcomes these limitations: dot map cartograms. These create a point pattern of cases while reshaping spatial units, such that spatial area becomes proportional to population size. We compared these dot map cartograms with standard dot map...
Source: Euro Surveill - June 29, 2017 Category: Infectious Diseases Authors: Soetens L, Hahné S, Wallinga J Tags: Euro Surveill Source Type: research

Genomic investigation of a suspected outbreak of Legionella pneumophila ST82 reveals undetected heterogeneity by the present gold-standard methods, Denmark, July to November 2014.
ons (ESGLI) Abstract Between July and November 2014, 15 community-acquired cases of Legionnaires´ disease (LD), including four with Legionella pneumophila serogroup 1 sequence type (ST) 82, were diagnosed in Northern Zealand, Denmark. An outbreak was suspected. No ST82 isolates were found in environmental samples and no external source was established. Four putative-outbreak ST82 isolates were retrospectively subjected to whole genome sequencing (WGS) followed by phylogenetic analyses with epidemiologically unrelated ST82 sequences. The four putative-outbreak ST82 sequences fell into two clades, the two clad...
Source: Euro Surveill - June 22, 2017 Category: Infectious Diseases Authors: Schjørring S, Stegger M, Kjelsø C, Lilje B, Bangsborg JM, Petersen RF, David S, Uldum SA, ESCMID Study Group for Legionella Infections (ESGLI) Tags: Euro Surveill Source Type: research

Fall in new HIV diagnoses among men who have sex with men (MSM) at selected London sexual health clinics since early 2015: testing or treatment or pre-exposure prophylaxis (PrEP)?
Abstract Since October 2015 up to September 2016, HIV diagnoses fell by 32% compared with October 2014-September 2015 among men who have sex with men (MSM) attending selected London sexual health clinics. This coincided with high HIV testing volumes and rapid initiation of treatment on diagnosis. The fall was most apparent in new HIV testers. Intensified testing of high-risk populations, combined with immediately received anti-retroviral therapy and a pre-exposure prophylaxis (PrEP) programme, may make elimination of HIV achievable. PMID: 28662762 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 22, 2017 Category: Infectious Diseases Authors: Brown AE, Mohammed H, Ogaz D, Kirwan PD, Yung M, Nash SG, Furegato M, Hughes G, Connor N, Delpech VC, Gill ON Tags: Euro Surveill Source Type: research

Baseline incidence of intussusception in early childhood before rotavirus vaccine introduction, the Netherlands, January 2008 to December 2012.
This study provides a first estimate of intussusception incidence in young children in the Netherlands from 1 January 2008 to 31 December 2012, which could be used for future rotavirus safety monitoring. Our estimates are based on two different sources: electronic medical records from the primary healthcare database (IPCI), as well as administrative data from the Dutch hospital register (LBZ). The results from our study indicate a low rate of intussusception. Overall incidence rate in children 
Source: Euro Surveill - June 22, 2017 Category: Infectious Diseases Authors: Gadroen K, Kemmeren JM, Bruijning-Verhagen PC, Straus SM, Weibel D, de Melker HE, Sturkenboom MC Tags: Euro Surveill Source Type: research

Third Director of the European Centre for Disease Prevention and Control takes office.
PMID: 28662765 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 22, 2017 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Clinical and laboratory evidence of Haff disease - case series from an outbreak in Salvador, Brazil, December 2016 to April 2017.
We describe a series of 15 Haff disease cases from an outbreak in Salvador, Brazil, starting early December 2016. Eleven cases were grouped in four family clusters of two to four individuals, four were isolated cases. All but one patient consumed cooked fish; 11 within 24h before symptoms onset. Cases consumed 'Olho de Boi' (Seriola spp.) and 'Badejo' (Mycteroperca spp.). A total of 67 cases were detected, the last case was reported on 5 April 2017. PMID: 28661391 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - June 15, 2017 Category: Infectious Diseases Authors: Bandeira AC, Campos GS, Ribeiro GS, Cardoso CW, Bastos CJ, Pessoa TL, Araujo KA, Grassi MFR, Castro AP, Carvalho RH, Prates APPB, Gois LL, Rocha VF, Sardi SI Tags: Euro Surveill Source Type: research

Botulism in Italy, 1986 to 2015.
Abstract Botulism is a rare but severe neuroparalytic disease caused by botulinum toxins. Because of its high potential impact on public health, botulism is a closely monitored communicable disease in Europe. In Italy, which has one of the highest incidence rates in Europe (0.03 cases per 100,000 population), botulism is monitored through a case-based passive surveillance system: the front-line physician who diagnoses a suspected case must notify the Local Health Units immediately, and the Ministry of Health's office within 12 hours. From 1986 to 2015, 466 confirmed cases of botulism were recorded in Italy (of 1,2...
Source: Euro Surveill - June 15, 2017 Category: Infectious Diseases Authors: Anniballi F, Auricchio B, Fiore A, Lonati D, Locatelli CA, Lista F, Fillo S, Mandarino G, De Medici D Tags: Euro Surveill Source Type: research