Challenges of investigating a large food-borne norovirus outbreak across all branches of a restaurant group in the United Kingdom, October 2016.
Abstract During October and November 2016, over 1,000 customers and staff reported gastroenteritis after eating at all 23 branches of a restaurant group in the United Kingdom. The outbreak coincided with a new menu launch and norovirus was identified as the causative agent. We conducted four retrospective cohort studies; one among all restaurant staff and three in customers at four branches. We investigated the dishes consumed, reviewed recipes, interviewed chefs and inspected restaurants to identify common ingredients and preparation methods for implicated dishes. Investigations were complicated by three public h...
Source: Euro Surveill - May 1, 2019 Category: Infectious Diseases Authors: Morgan M, Watts V, Allen D, Curtis D, Kirolos A, Macdonald N, Maslen E, Morgan D, Saei A, Sedgwick J, Stevenson J, Turbitt D, Vivancos R, Waugh C, Williams C, Decraene V Tags: Euro Surveill Source Type: research

Estimating age-specific vaccine effectiveness using data from a large measles outbreak in Berlin, Germany, 2014/15: evidence for waning immunity.
ConclusionVE for MCV2 was generally high, but lower in those aged 31-42 years old. The estimated proportion with MCV2 should have led to sufficient herd immunity in those aged 31-42 years old. Thus, lower VE cannot be fully explained by natural immunity, suggesting presence of waning immunity. PMID: 31039834 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Bitzegeio J, Majowicz S, Matysiak-Klose D, Sagebiel D, Werber D Tags: Euro Surveill Source Type: research

Measles outbreak in Gothenburg urban area, Sweden, 2017 to 2018: low viral load in breakthrough infections.
The objective of this study was to compare measles RNA levels between naïve (i.e. primary) and breakthrough infections. We also propose a fast provisional classification of breakthrough infections. Medical records were reviewed and real-time PCR-positive samples genotyped. Cases were classified as naïve, breakthrough or vaccine infections. We compared clinical symptoms and measles RNA cycle threshold (Ct) values between breakthrough and naïve infections. Sixteen of 28 confirmed cases of measles in this outbreak were breakthrough infections. A fast provisional classification, based on previous history of meas...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Sundell N, Dotevall L, Sansone M, Andersson M, Lindh M, Wahlberg T, Tyrberg T, Westin J, Liljeqvist JÅ, Bergström T, Studahl M, Andersson LM Tags: Euro Surveill Source Type: research

Spatiotemporal distribution and determinants of measles incidence during a large outbreak, Italy, September 2016 to July 2018.
ConclusionThe spread of measles between September 2016 and July 2018 in Italy indicates the need to improve VC and to explore further how societal and other parameters might be linked to incidence. PMID: 31039836 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Andrianou XD, Del Manso M, Bella A, Vescio MF, Baggieri M, Rota MC, Pezzotti P, Filia A Tags: Euro Surveill Source Type: research

One Health approach for West Nile virus surveillance in the European Union: relevance of equine data for blood safety.
Abstract West Nile virus (WNV) infection is notifiable in humans and equids in the European Union (EU). An area where a human case is detected is considered affected until the end of the mosquito transmission season (week 48) and blood safety measures have to be implemented. We used human and equine case notifications between 2013 and 2017 to define the WNV distribution in the EU and to investigate the relevance of using equine cases as a complementary trigger for blood safety measures. Adding areas with equine cases to the definition of an affected area would have a major impact on blood safety measures. Adding a...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Young JJ, Coulombier D, Domanović D, European Union West Nile Fever Working Group, Zeller H, Gossner CM Tags: Euro Surveill Source Type: research

Detection of colistin resistance mcr-1 gene in Salmonella enterica serovar Rissen isolated from mussels, Spain, 2012- to 2016.
Abstract Nineteen Salmonella strains were isolated from 5,907 randomly selected mussel samples during a monitoring programme for the presence of Salmonella in shellfish in Galicia, north-west Spain (2012-16). Serovars, sequence type and antimicrobial resistance genes were determined through genome sequencing. Presence of the mcr-1 gene in one strain belonging to serovar Rissen and ST-469 was identified. The mcr-1 gene had not been isolated previously in environmental Salmonella isolated from mussels in Spain. PMID: 31014417 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Lozano-Leon A, Garcia-Omil C, Dalama J, Rodriguez-Souto R, Martinez-Urtaza J, Gonzalez-Escalona N Tags: Euro Surveill Source Type: research

Outbreak of Shiga toxin-producing Escherichia coli O157:H7 linked to raw drinking milk resolved by rapid application of advanced pathogen characterisation methods, England, August to October 2017.
Abstract An outbreak of Shiga toxin-producing Escherichia coli (STEC) O157:H7 occurred on the Isle of Wight between August and October 2017. Of the seven cases linked to the outbreak, five were identified through the statutory notification process and two were identified through national surveillance of whole genome sequencing data. Enhanced surveillance questionnaires established a common link to a farm, and link to the likely food vehicle, raw drinking milk (RDM). Microbiological investigations, including PCR, identified the presence of STEC O157:H7 in samples of RDM. Analysis of core genome single nucleotide po...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Treacy J, Jenkins C, Paranthaman K, Jorgensen F, Mueller-Doblies D, Anjum M, Kaindama L, Hartman H, Kirchner M, Carson T, Kar-Purkayastha I Tags: Euro Surveill Source Type: research

Author's correction for Euro Surveill. 2019;24(14).
PMID: 31017085 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Group A rotavirus surveillance before vaccine introduction in Italy, September 2014 to August 2017.
ConclusionsThe emergence of G12P[8] rotavirus in Italy, as in other countries, marks this genotype as the sixth most common human genotype. Continuous surveillance of RVA strains and monitoring of circulating genotypes are important for a better understanding of rotavirus evolution and genotype distribution, particularly regarding strains that may emerge from reassortment events. PMID: 30994104 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Ianiro G, Micolano R, Di Bartolo I, Scavia G, Monini M, RotaNet-Italy Study Group Tags: Euro Surveill Source Type: research

Changing epidemiology of meticillin-resistant Staphylococcus aureus in 42 hospitals in the Dutch-German border region, 2012 to 2016: results of the search-and-follow-policy.
We describe MRSA colonisation/infection and bacteraemia rate trends in Dutch-German border region hospitals (NL-DE-BRH) in 2012-16.MethodsAll 42 NL-DE BRH (8 NL-BRH, 34 DE-BRH) within the cross-border network EurSafety Health-net provided surveillance data (on average ca 620,000 annual hospital admissions, of these 68.0% in Germany). Guidelines defining risk for MRSA colonisation/infection were reviewed. MRSA-related parameters and healthcare utilisation indicators were derived. Medians over the study period were compared between NL- and DE-BRH.ResultsMeasures for MRSA cases were similar in both countries, however defining...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Jurke A, Daniels-Haardt I, Silvis W, Berends MS, Glasner C, Becker K, Köck R, Friedrich AW Tags: Euro Surveill Source Type: research

Missed opportunities for HIV testing in people diagnosed with HIV, Estonia, 2014 to 2015.
ConclusionsThe HIV testing rate in the 2 years before an HIV diagnosis was very low, even in the presence of an HIV indicator condition. This emphasises the importance of implementing the Estonian HIV testing guidelines. PMID: 30994106 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Rüütel K, Lemsalu L, Lätt S, Epštein J, On Behalf Of OptTEST By HiE Tags: Euro Surveill Source Type: research

Children under 10 years of age were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic in Canada: ‎possible cohort effect following the 2009 influenza pandemic.
Children under 10 years of age were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic in Canada: ‎possible cohort effect following the 2009 influenza pandemic. Euro Surveill. 2019 Apr;24(15): Authors: Skowronski DM, Leir S, De Serres G, Murti M, Dickinson JA, Winter AL, Olsha R, Croxen MA, Drews SJ, Charest H, Martineau C, Sabaiduc S, Bastien N, Li Y, Petric M, Jassem A, Krajden M, Gubbay JB Abstract IntroductionFindings from the community-based Canadian Sentinel Practitioner Surveillance Network (SPSN) suggest children were more affected by the 2018/19 influenza A(H1N1)pdm09 epidemic.A...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Skowronski DM, Leir S, De Serres G, Murti M, Dickinson JA, Winter AL, Olsha R, Croxen MA, Drews SJ, Charest H, Martineau C, Sabaiduc S, Bastien N, Li Y, Petric M, Jassem A, Krajden M, Gubbay JB Tags: Euro Surveill Source Type: research

Outbreak of hepatitis A virus infection in Taiwan, June 2015 to September 2017.
Abstract The Taiwan Centers for Disease Control (CDC) were notified of increasing acute hepatitis A (AHA) in June 2015. Serum and/or stool from AHA patients and sewage samples were tested for hepatitis A virus (HAV). We defined outbreak cases as AHA patients with illness onset after June 2015 and with an HAV sequence less than 0.5% different from that of the TA-15 outbreak strain. We analysed characteristics and food exposures between outbreak and non-outbreak cases between January 2014 (start of enhanced surveillance) and February 2016. From June 2015 to September 2017, there were 1,563 AHA patients...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Chen WC, Chiang PH, Liao YH, Huang LC, Hsieh YJ, Chiu CM, Lo YC, Yang CH, Yang JY Tags: Euro Surveill Source Type: research

Mortality attributable to seasonal influenza in Greece, 2013 to 2017: variation by type/subtype and age, and a possible harvesting effect.
ConclusionsStudies of influenza-attributable mortality need to consider distributed-lag effects, stratify by age group and adjust both for circulating influenza virus types/subtypes and daily mean temperatures, in order to produce reliable estimates. Our approach addresses these issues, is readily applicable in the context of influenza surveillance, and can be useful for other countries. PMID: 30968823 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Lytras T, Pantavou K, Mouratidou E, Tsiodras S Tags: Euro Surveill Source Type: research

Challenges in modelling the proportion of undiagnosed HIV infections in Sweden.
ConclusionsThe proportion of undiagnosed PLHIV in Sweden is uncertain. SSOPHIE estimates had wide PR. The ECDC model estimates were unreliable because migration was not accounted for. Better migration data and estimation methods are required to obtain reliable estimates of proportions of undiagnosed PLHIV in similar settings. PMID: 30968824 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Andersson E, Nakagawa F, van Sighem A, Axelsson M, Phillips AN, Sönnerborg A, Albert J Tags: Euro Surveill Source Type: research

The seroprevalence of untreated chronic hepatitis C virus (HCV) infection and associated risk factors in male Irish prisoners: a cross-sectional study, 2017.
Abstract IntroductionData on chronic hepatitis C (HCV) infection prevalence in European prisons are incomplete and impact the public health opportunity that incarceration provides.AimsWe aimed to estimate the seroprevalence of untreated chronic HCV infection and to identify associated risk factors in an Irish male prison.MethodsWe conducted a cross-sectional study involving a researcher-administered questionnaire, review of medical records and HCV serology.ResultsOf 422 prisoners (78.0% of the study population) who participated in the study, 298 (70.6%) completed the questionnaire and 403 (95.5%) were tested for H...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Crowley D, Lambert JS, Betts-Symonds G, Cullen W, Keevans M, Kelly E, Laird E, McHugh T, McKiernan S, Miggin SJ, Murphy C, Murtagh R, O'Reilly D, Tobin C, Van Hout MC Tags: Euro Surveill Source Type: research

Erratum for Euro Surveill. 2019;24(13).
PMID: 30968826 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Increase of invasive meningococcal serogroup W disease in Europe, 2013 to 2017.
C, Musilek M, Born R, Vogel U, Borrow R Abstract BackgroundThe total incidence of invasive meningococcal disease (IMD) in Europe has been declining in recent years; however, a rising incidence due to serogroup W (MenW), predominantly sequence type 11 (ST-11), clonal complex 11 (cc11), was reported in some European countries.AimThe aim of this study was to compile the most recent laboratory surveillance data on MenW IMD from several European countries to assess recent trends in Europe.MethodsIn this observational, retrospective study, IMD surveillance data collected from 2013-17 by national reference laboratories a...
Source: Euro Surveill - April 1, 2019 Category: Infectious Diseases Authors: Krone M, Gray S, Abad R, Skoczyńska A, Stefanelli P, van der Ende A, Tzanakaki G, Mölling P, João Simões M, Křížová P, Emonet S, Caugant DA, Toropainen M, Vazquez J, Waśko I, Knol MJ, Jacobsson S, Rodrigues Bettencourt C, Musilek M, Born R, Vogel Tags: Euro Surveill Source Type: research

Computer-assisted, high-frequency, hospital-wide point prevalence surveys of hospital-acquired infections in a tertiary care hospital, the Netherlands, 2013 to 2014.
ConclusionPerforming computer-assisted, high frequency hospital-wide PPS, is a feasible method that will detect even subtle changes in HAI prevalence over time. PMID: 30940313 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Streefkerk HRA, Willemsen SP, van der Hoeven CP, Vos MC, Verkooijen RP, Verbrugh HA Tags: Euro Surveill Source Type: research

Increased prevalence of Escherichia coli strains from food carrying bla NDM and mcr-1-bearing plasmids that structurally resemble those of clinical strains, China, 2015 to 2017.
Abstract IntroductionEmergence of resistance determinants of bla NDM and mcr-1 has undermined the antimicrobial effectiveness of the last line drugs carbapenems and colistin.AimThis work aimed to assess the prevalence of bla NDM and mcr-1 in E. coli strains collected from food in Shenzhen, China, during the period 2015 to 2017.MethodsMultidrug-resistant E. coli strains were isolated from food samples. Plasmids encoding mcr-1 or bla NDM genes were characterised and compared with plasmids found in clinical isolates.ResultsAmong 1,166 non-repeated cephalosporin-resistant E. coli strains isolated from 2,147 food sampl...
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Liu X, Geng S, Chan EW, Chen S Tags: Euro Surveill Source Type: research

Outbreak of Salmonella enterica serotype Poona in infants linked to persistent Salmonella contamination in an infant formula manufacturing facility, France, August 2018 to February 2019.
We describe a Salmonella Poona outbreak involving 31 infant cases in France. Following outbreak detection on 18 January 2019, consumption of rice-based infant formula manufactured at a facility in Spain was identified as the probable cause, leading to a recall on 24 January. Whole genome sequencing analysis linked present outbreak isolates to a 2010-11 S. Poona outbreak in Spain associated with formula manufactured in the same facility, indicating a persistent source of contamination. PMID: 30940315 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Jones G, Pardos de la Gandara M, Herrera-Leon L, Herrera-Leon S, Varela Martinez C, Hureaux-Roy R, Abdallah Y, Nisavanh A, Fabre L, Renaudat C, Mossong J, Mattheus W, Huard C, Le Borgne C, de Valk H, Weill FX, Jourdan-Da Silva N Tags: Euro Surveill Source Type: research

Clonal expansion of community-associated meticillin-resistant Staphylococcus aureus (MRSA) in people who inject drugs (PWID): prevalence, risk factors and molecular epidemiology, Bristol, United Kingdom, 2012 to 2017.
CONCLUSIONS: MRSA colonisation in Bristol PWID is substantially elevated compared with general population estimates and there is evidence of clonal expansion, community-based transmission and increased infection risk related to the colonising strain. Targeted interventions, including community screening and suppression therapy, education and basic infection control are needed to reduce MRSA infections in PWID. PMID: 30940316 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Packer S, Pichon B, Thompson S, Neale J, Njoroge J, Kwiatkowska RM, Oliver I, Telfer M, Doumith M, Buunaaisie C, Heinsbroek E, Hopewell-Kelly N, Desai M, Hope V, Williams OM, Kearns A, Hickman M, Gobin M Tags: Euro Surveill Source Type: research

In the national epidemiological bulletins - a selection from recent issues.
PMID: 30940317 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Exploring Campylobacter seasonality across Europe using The European Surveillance System (TESSy), 2008 to 2016.
ConclusionAcross Europe, the strength and timing of campylobacteriosis peaks have remained similar to those observed previously. In addition, TESSy is a useful resource for cross-European seasonal analysis of infectious diseases such as campylobacteriosis, but its utility depends upon each country's reporting infrastructure. PMID: 30940318 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Lake IR, Colón-González FJ, Takkinen J, Rossi M, Sudre B, Dias JG, Tavoschi L, Joshi A, Semenza JC, Nichols G Tags: Euro Surveill Source Type: research

Authors' response: Prevention of bacterial sexually transmitted infections (STI) in France: a comprehensive approach.
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Authors' response: Prevention of bacterial sexually transmitted infections (STI) in France: a comprehensive approach. Tags: Euro Surveill Source Type: research

Tuberculosis in the European Union/European Economic Area: much progress, still many challenges.
PMID: 30914075 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Guthmann JP, Haas W Tags: Euro Surveill Source Type: research

Visual tools to assess the plausibility of algorithm-identified infectious disease clusters: an application to mumps data from the Netherlands dating from January 2009 to June 2016.
ConclusionOur tools for assessing automatically identified clusters allow outbreak investigators to rapidly spot plausible transmission clusters for mumps and other human-to-human transmissible diseases. This fast information processing potentially reduces workload. PMID: 30914076 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Soetens L, Backer JA, Hahné S, van Binnendijk R, Gouma S, Wallinga J Tags: Euro Surveill Source Type: research

Will we reach the Sustainable Development Goals target for tuberculosis in the European Union/European Economic Area by 2030?
Werf MJ Abstract We assessed progress towards the Sustainable Development Goals target for tuberculosis in the European Union/European Economic Area using the latest tuberculosis (TB) surveillance and Eurostat data. Both the TB notification rate and the number of TB deaths were decreasing before 2015 and the TB notification rate further declined between 2015 and 2017. With the current average decline in notification rate and number of TB deaths however, the EU/EEA will not reach the targets by 2030. PMID: 30914077 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Merk H, Ködmön C, van der Werf MJ Tags: Euro Surveill Source Type: research

Influenza A(H3N2) virus exhibiting reduced susceptibility to baloxavir due to a polymerase acidic subunit I38T substitution detected from a hospitalised child without prior baloxavir treatment, Japan, January 2019.
Abstract In January 2019, two influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic subunit (PA), which confers reduced susceptibility to baloxavir, were detected from epidemiologically unrelated hospitalised children in Japan. The viruses exhibited reduced susceptibility to baloxavir but were susceptible to neuraminidase inhibitors. Only one of the two children had been treated with baloxavir. An epidemiological analysis suggests possible transmission of the PA I38T mutant A(H3N2) virus among humans. PMID: 30914078 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Takashita E, Kawakami C, Ogawa R, Morita H, Fujisaki S, Shirakura M, Miura H, Nakamura K, Kishida N, Kuwahara T, Ota A, Togashi H, Saito A, Mitamura K, Abe T, Ichikawa M, Yamazaki M, Watanabe S, Odagiri T Tags: Euro Surveill Source Type: research

Letter to the editor: Prevention of bacterial sexually transmitted infections (STI) in France: why not recommend using condoms and safer sex?
PMID: 30914079 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Caumes E Tags: Euro Surveill Source Type: research

Influenza surveillance: determining the epidemic threshold for influenza by using the Moving Epidemic Method (MEM), Montenegro, 2010/11 to 2017/18 influenza seasons.
CONCLUSIONS: Our study marks the first attempt to determine the pre/post-epidemic threshold values for the epidemic period in Montenegro. The findings will allow a more detailed examination of the influenza-related epidemiological situation, timely detection of epidemic and contribute to the development of more efficient measures for disease prevention and control aimed at reducing the influenza-associated morbidity and mortality. PMID: 30914080 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Rakocevic B, Grgurevic A, Trajkovic G, Mugosa B, Sipetic Grujicic S, Medenica S, Bojovic O, Lozano Alonso JE, Vega T Tags: Euro Surveill Source Type: research

Isoniazid (INH) mono-resistance and tuberculosis (TB) treatment success: analysis of European surveillance data, 2002 to 2014.
CONCLUSIONS: This study provides evidence for an association between INH mono-resistance and a lower likelihood of TB treatment success. Increased attention should be paid to timely detection and management of INH mono-resistant TB. PMID: 30914081 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Karo B, Kohlenberg A, Hollo V, Duarte R, Fiebig L, Jackson S, Kearns C, Ködmön C, Korzeniewska-Kosela M, Papaventsis D, Solovic I, van Soolingen D, van der Werf MJ Tags: Euro Surveill Source Type: research

Cost-effectiveness of measles control during elimination in Ontario, Canada, 2015.
ConclusionsOntario's measles outbreak response exceeds generally accepted cost-effectiveness thresholds and may not be the most efficient use of public health resources from a healthcare payer perspective. These findings should be balanced against benefits of increased vaccine coverage and maintaining elimination status. PMID: 30892178 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Ramsay LC, Crowcroft NS, Thomas S, Aruffo E, Teslya A, Heffernan JM, Gournis E, Hiebert J, Jaeger V, Jiaravuthisan M, Sharron J, Severini A, Deeks SL, Gubbay J, Mazzulli T, Sander B Tags: Euro Surveill Source Type: research

Travellers as sentinels of chikungunya epidemics: a family cluster among Finnish travellers to Koh Lanta, Thailand, January 2019.
Abstract In January 2019, five of 11 travellers to Koh Lanta, Thailand, contracted chikungunya, symptoms starting 4 days after presumed transmission. Four cases were hospitalised, one child treated in intensive care; 6 weeks after disease onset, all three adults have persistent arthralgias/arthritis, incapacitating for two. Together with a recent report of eight chikungunya cases among travellers to various destinations in Thailand, the high attack rate in our cluster points to an ongoing outbreak in the country. PMID: 30892179 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Kantele A Tags: Euro Surveill Source Type: research

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.
Abstract IntroductionIn 2007, a new federal legislation in Belgium prohibited non-biosafety level 3 laboratories to process culture tubes suspected of containing mycobacteria.AimTo present mycobacterial surveillance/diagnosis data from the Belgian National Reference Centre for mycobacteria (NRC) from 2007 to 2016.MethodsThis retrospective observational study investigated the numbers of analyses at the NRC and false positive cultures (interpreted as containing mycobacteria at referring clinical laboratories, but with no mycobacterial DNA detected by PCR in the NRC). We reviewed mycobacterial species identified and ...
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Soetaert K, Subissi L, Ceyssens PJ, Vanfleteren B, Chantrenne M, Asikainen T, Duysburgh E, Mathys V Tags: Euro Surveill Source Type: research

Epidemiology of Lyme borreliosis through two surveillance systems: the national Sentinelles GP network and the national hospital discharge database, France, 2005 to 2016.
CONCLUSION: Public health strategies should focus on high-incidence age groups and regions during the months with the highest incidences and should emphasise prevention measures such as regular tick checks after exposure and prompt removal to avoid infection. PMID: 30892181 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Septfons A, Goronflot T, Jaulhac B, Roussel V, De Martino S, Guerreiro S, Launay T, Fournier L, De Valk H, Figoni J, Blanchon T, Couturier E Tags: Euro Surveill Source Type: research

A comparative analysis of prophylactic antimicrobial use in long-term care facilities in Ireland, 2013 and 2016.
ConclusionsForty per cent of antimicrobial prescriptions in Irish LTCFs were prophylactic. This practice is not consistent with national antimicrobial prescribing guidelines. Addressing inappropriate prophylaxis prescribing in Irish LTCFs should be a key objective of antimicrobial stewardship initiatives. PMID: 30892182 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Tandan M, O'Connor R, Burns K, Murphy H, Hennessy S, Roche F, Donlon S, Cormican M, Vellinga A Tags: Euro Surveill Source Type: research

Influenza C virus in pre-school children with respiratory infections: retrospective analysis of data from the national influenza surveillance system in Germany, 2012 to 2014.
ConclusionOur data are the first on influenza C virus circulation in Germany and notably from a European national surveillance system. The low detection frequency and the identified virus variants confirm earlier observations outside a surveillance system. More virus detections during the 2012/13 season indicate a variable circulation intensity in the different years studied. Influenza C virus can be considered for ILI patients. Future studies addressing its clinical impact, especially in patients with severe disease are needed. PMID: 30862333 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Fritsch A, Schweiger B, Biere B Tags: Euro Surveill Source Type: research

HEVnet: a One Health, collaborative, interdisciplinary network and sequence data repository for enhanced hepatitis E virus molecular typing, characterisation and epidemiological investigations.
Abstract Hepatitis E virus (HEV) is a common cause of acute hepatitis worldwide. In Europe, HEV is a zoonosis transmitted via contaminated pork meat or other pork food products. Genotype 3 is the most prevalent HEV type in the animal reservoir, as well as in humans. Despite an increased incidence of hepatitis E across Europe, much remains unknown about its spread, sources and transmission routes. A One Health approach is crucial to better understand the (molecular) epidemiology of HEV. HEVnet was established in April 2017 as a network and database for sharing sequences and accompanying metadata collected from huma...
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Mulder AC, Kroneman A, Franz E, Vennema H, Tulen AD, Takkinen J, Hofhuis A, Adlhoch C, Members Of HEVnet Tags: Euro Surveill Source Type: research

Increased risk of chikungunya infection in travellers to Thailand during ongoing outbreak in tourist areas: cases imported to Europe and the Middle East, early 2019.
We report nine travellers with confirmed chikungunya virus infection, returning from tourist areas of Thailand to Sweden, Switzerland, the United Kingdom, Romania, Israel and France, diagnosed in January and February 2019. These sentinel tourists support the intensification of chikungunya virus circulation in Thailand and highlight the potential for importation to areas at risk of local transmission. PMID: 30862335 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Javelle E, Florescu SA, Asgeirsson H, Jmor S, Eperon G, Leshem E, Blum J, Molina I, Field V, Pietroski N, Eldin C, Johnston V, Cotar IA, Popescu C, Hamer DH, Gautret P Tags: Euro Surveill Source Type: research

Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018.
We describe detection in the United Kingdom (UK) of the drug-resistant Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate azithromycin resistance. Two female patients developed infection following contact with UK-resident men from the same sexual network linked to travel to Ibiza, Spain. One case failed treatment with ceftriaxone, and azithromycin and gentamicin, before successful treatment with ertapenem. Both isolates had indistinguishable whole-genome sequences. Urgent action is essential to contain this drug-resistant strain. PMID: 30862336 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Eyre DW, Town K, Street T, Barker L, Sanderson N, Cole MJ, Mohammed H, Pitt R, Gobin M, Irish C, Gardiner D, Sedgwick J, Beck C, Saunders J, Turbitt D, Cook C, Phin N, Nathan B, Horner P, Fifer H Tags: Euro Surveill Source Type: research

Epidemiology and genotype 3 subtype dynamics of hepatitis E virus in Belgium, 2010 to 2017.
ConclusionThe increasing trend of HEV diagnoses in Belgium may be largely explained by increased awareness and testing. PMID: 30862337 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Suin V, Klamer SE, Hutse V, Wautier M, Jacques M, Abady M, Lamoral S, Verburgh V, Thomas I, Brochier B, Subissi L, Van Gucht S Tags: Euro Surveill Source Type: research

Hepatitis E virus in blood donors in England, 2016 to 2017: from selective to universal screening.
ConclusionHEV screening of blood donations is a vital step in order to provide safer blood for all recipients, but especially for the immunosuppressed. The unusually high rates of HEV infection in young blood donors may provide some insight into specific risks associated with HEV infection in England. PMID: 30862338 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Harvala H, Hewitt PE, Reynolds C, Pearson C, Haywood B, Tettmar KI, Ushiro-Lumb I, Brailsford SR, Tedder R, Ijaz S Tags: Euro Surveill Source Type: research

Call for papers for a special issue on how point of care/point of impact testing (POCT/ POIT) and self-testing impact surveillance and public health.
PMID: 30808437 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Job vacancy at the European Centre for Disease Prevention and Control.
PMID: 30808438 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Analysis of exotic squirrel trade and detection of human infections with variegated squirrel bornavirus 1, Germany, 2005 to 2018.
sit J Abstract Following the discovery in 2015 of the variegated squirrel bornavirus 1 (VSBV-1) in fatal encephalitis cases among exotic squirrel breeders and a zoo animal caretaker in Germany, a case definition was developed. It was employed during trace-back animal trade investigations and sero-epidemiological studies among breeders and zoo animal caretakers of holdings with VSBV-1 infected squirrels. During the investigation, two possible human cases who had died of encephalitis were identified retrospectively among the squirrel breeders. Moreover, one probable human case was detected among the breeders who had...
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Tappe D, Frank C, Homeier-Bachmann T, Wilking H, Allendorf V, Schlottau K, Muñoz-Fontela C, Rottstegge M, Port JR, Rissland J, Eisermann P, Beer M, Schmidt-Chanasit J Tags: Euro Surveill Source Type: research

Interim 2018/19 influenza vaccine effectiveness: six European studies, October 2018 to January 2019.
Abstract Influenza A(H1N1)pdm09 and A(H3N2) viruses both circulated in Europe in October 2018-January 2019. Interim results from six studies indicate that 2018/19 influenza vaccine effectiveness (VE) estimates among all ages in primary care was 32-43% against influenza A; higher against A(H1N1)pdm09 and lower against A(H3N2). Among hospitalised older adults, VE estimates were 34-38% against influenza A and slightly lower against A(H1N1)pdm09. Influenza vaccination is of continued benefit during the ongoing 2018/19 influenza season. PMID: 30808440 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Kissling E, Rose A, Emborg HD, Gherasim A, Pebody R, Pozo F, Trebbien R, Mazagatos C, Whitaker H, Valenciano M, European Ive Group Tags: Euro Surveill Source Type: research

Tracking Rift Valley fever: From Mali to Europe and other countries, 2016.
nti V Abstract On 16 September 2016, the World Health Organization confirmed a Rift Valley fever (RVF) outbreak in Niger. Epidemiological surveillance was reinforced among the French Armed Forces deployed in Niger and bordering countries: Chad, Mali and Burkina Faso. On 26 October, a probable case of RVF was reported in a service member sampled in Mali 3 weeks earlier. At the time the result was reported, the patient was on vacation on Martinique. An epidemiological investigation was conducted to confirm this case and identify other cases. Finally, the case was not confirmed, but three suspected cases of RVF were ...
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Tong C, Javelle E, Grard G, Dia A, Lacrosse C, Fourié T, Gravier P, Watier-Grillot S, Lancelot R, Letourneur F, Comby F, Grau M, Cassou L, Meynard JB, Briolant S, Leparc-Goffart I, Pommier de Santi V Tags: Euro Surveill Source Type: research

Paediatric haemolytic uraemic syndrome related to Shiga toxin-producing Escherichia coli, an overview of 10 years of surveillance in France, 2007 to 2016.
Surveillance du Shu Pédiatrique Abstract IntroductionHaemolytic uraemic syndrome (HUS) related to Shiga toxin-producing Escherichia coli (STEC) is the leading cause of acute renal failure in young children. In France, HUS surveillance in children aged 
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Bruyand M, Mariani-Kurkdjian P, Le Hello S, King LA, Van Cauteren D, Lefevre S, Gouali M, Jourdan-da Silva N, Mailles A, Donguy MP, Loukiadis E, Sergentet-Thevenot D, Loirat C, Bonacorsi S, Weill FX, De Valk H, Réseau Français Hospitalier de Surveillanc Tags: Euro Surveill Source Type: research

Implementation and evaluation of the human papillomavirus (HPV) vaccination pilot for men who have sex with men (MSM), England, April 2016 to March 2017.
CONCLUSION: An opportunistic HPV vaccination programme for MSM can be delivered in an acceptable and, as far as can be evaluated, equitable manner, without major disruption to SHC and HIV clinics. PMID: 30808443 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Edelstein M, Iyanger N, Hennessy N, Mesher D, Checchi M, Soldan K, McCall M, Nugent J, Crofts J, Lo J, Gilson R, Powell K, Ramsay M, Yarwood J Tags: Euro Surveill Source Type: research