Authors' response: Prevention of bacterial sexually transmitted infections (STI) in France: a comprehensive approach.
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Authors' response: Prevention of bacterial sexually transmitted infections (STI) in France: a comprehensive approach. Tags: Euro Surveill Source Type: research

Tuberculosis in the European Union/European Economic Area: much progress, still many challenges.
PMID: 30914075 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Guthmann JP, Haas W Tags: Euro Surveill Source Type: research

Visual tools to assess the plausibility of algorithm-identified infectious disease clusters: an application to mumps data from the Netherlands dating from January 2009 to June 2016.
ConclusionOur tools for assessing automatically identified clusters allow outbreak investigators to rapidly spot plausible transmission clusters for mumps and other human-to-human transmissible diseases. This fast information processing potentially reduces workload. PMID: 30914076 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Soetens L, Backer JA, Hahné S, van Binnendijk R, Gouma S, Wallinga J Tags: Euro Surveill Source Type: research

Will we reach the Sustainable Development Goals target for tuberculosis in the European Union/European Economic Area by 2030?
Werf MJ Abstract We assessed progress towards the Sustainable Development Goals target for tuberculosis in the European Union/European Economic Area using the latest tuberculosis (TB) surveillance and Eurostat data. Both the TB notification rate and the number of TB deaths were decreasing before 2015 and the TB notification rate further declined between 2015 and 2017. With the current average decline in notification rate and number of TB deaths however, the EU/EEA will not reach the targets by 2030. PMID: 30914077 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Merk H, Ködmön C, van der Werf MJ Tags: Euro Surveill Source Type: research

Influenza A(H3N2) virus exhibiting reduced susceptibility to baloxavir due to a polymerase acidic subunit I38T substitution detected from a hospitalised child without prior baloxavir treatment, Japan, January 2019.
Abstract In January 2019, two influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic subunit (PA), which confers reduced susceptibility to baloxavir, were detected from epidemiologically unrelated hospitalised children in Japan. The viruses exhibited reduced susceptibility to baloxavir but were susceptible to neuraminidase inhibitors. Only one of the two children had been treated with baloxavir. An epidemiological analysis suggests possible transmission of the PA I38T mutant A(H3N2) virus among humans. PMID: 30914078 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Takashita E, Kawakami C, Ogawa R, Morita H, Fujisaki S, Shirakura M, Miura H, Nakamura K, Kishida N, Kuwahara T, Ota A, Togashi H, Saito A, Mitamura K, Abe T, Ichikawa M, Yamazaki M, Watanabe S, Odagiri T Tags: Euro Surveill Source Type: research

Letter to the editor: Prevention of bacterial sexually transmitted infections (STI) in France: why not recommend using condoms and safer sex?
PMID: 30914079 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Caumes E Tags: Euro Surveill Source Type: research

Influenza surveillance: determining the epidemic threshold for influenza by using the Moving Epidemic Method (MEM), Montenegro, 2010/11 to 2017/18 influenza seasons.
CONCLUSIONS: Our study marks the first attempt to determine the pre/post-epidemic threshold values for the epidemic period in Montenegro. The findings will allow a more detailed examination of the influenza-related epidemiological situation, timely detection of epidemic and contribute to the development of more efficient measures for disease prevention and control aimed at reducing the influenza-associated morbidity and mortality. PMID: 30914080 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Rakocevic B, Grgurevic A, Trajkovic G, Mugosa B, Sipetic Grujicic S, Medenica S, Bojovic O, Lozano Alonso JE, Vega T Tags: Euro Surveill Source Type: research

Isoniazid (INH) mono-resistance and tuberculosis (TB) treatment success: analysis of European surveillance data, 2002 to 2014.
CONCLUSIONS: This study provides evidence for an association between INH mono-resistance and a lower likelihood of TB treatment success. Increased attention should be paid to timely detection and management of INH mono-resistant TB. PMID: 30914081 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Karo B, Kohlenberg A, Hollo V, Duarte R, Fiebig L, Jackson S, Kearns C, Ködmön C, Korzeniewska-Kosela M, Papaventsis D, Solovic I, van Soolingen D, van der Werf MJ Tags: Euro Surveill Source Type: research

Cost-effectiveness of measles control during elimination in Ontario, Canada, 2015.
ConclusionsOntario's measles outbreak response exceeds generally accepted cost-effectiveness thresholds and may not be the most efficient use of public health resources from a healthcare payer perspective. These findings should be balanced against benefits of increased vaccine coverage and maintaining elimination status. PMID: 30892178 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Ramsay LC, Crowcroft NS, Thomas S, Aruffo E, Teslya A, Heffernan JM, Gournis E, Hiebert J, Jaeger V, Jiaravuthisan M, Sharron J, Severini A, Deeks SL, Gubbay J, Mazzulli T, Sander B Tags: Euro Surveill Source Type: research

Travellers as sentinels of chikungunya epidemics: a family cluster among Finnish travellers to Koh Lanta, Thailand, January 2019.
Abstract In January 2019, five of 11 travellers to Koh Lanta, Thailand, contracted chikungunya, symptoms starting 4 days after presumed transmission. Four cases were hospitalised, one child treated in intensive care; 6 weeks after disease onset, all three adults have persistent arthralgias/arthritis, incapacitating for two. Together with a recent report of eight chikungunya cases among travellers to various destinations in Thailand, the high attack rate in our cluster points to an ongoing outbreak in the country. PMID: 30892179 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Kantele A Tags: Euro Surveill Source Type: research

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.
Abstract IntroductionIn 2007, a new federal legislation in Belgium prohibited non-biosafety level 3 laboratories to process culture tubes suspected of containing mycobacteria.AimTo present mycobacterial surveillance/diagnosis data from the Belgian National Reference Centre for mycobacteria (NRC) from 2007 to 2016.MethodsThis retrospective observational study investigated the numbers of analyses at the NRC and false positive cultures (interpreted as containing mycobacteria at referring clinical laboratories, but with no mycobacterial DNA detected by PCR in the NRC). We reviewed mycobacterial species identified and ...
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Soetaert K, Subissi L, Ceyssens PJ, Vanfleteren B, Chantrenne M, Asikainen T, Duysburgh E, Mathys V Tags: Euro Surveill Source Type: research

Epidemiology of Lyme borreliosis through two surveillance systems: the national Sentinelles GP network and the national hospital discharge database, France, 2005 to 2016.
CONCLUSION: Public health strategies should focus on high-incidence age groups and regions during the months with the highest incidences and should emphasise prevention measures such as regular tick checks after exposure and prompt removal to avoid infection. PMID: 30892181 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Septfons A, Goronflot T, Jaulhac B, Roussel V, De Martino S, Guerreiro S, Launay T, Fournier L, De Valk H, Figoni J, Blanchon T, Couturier E Tags: Euro Surveill Source Type: research

A comparative analysis of prophylactic antimicrobial use in long-term care facilities in Ireland, 2013 and 2016.
ConclusionsForty per cent of antimicrobial prescriptions in Irish LTCFs were prophylactic. This practice is not consistent with national antimicrobial prescribing guidelines. Addressing inappropriate prophylaxis prescribing in Irish LTCFs should be a key objective of antimicrobial stewardship initiatives. PMID: 30892182 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Tandan M, O'Connor R, Burns K, Murphy H, Hennessy S, Roche F, Donlon S, Cormican M, Vellinga A Tags: Euro Surveill Source Type: research

Influenza C virus in pre-school children with respiratory infections: retrospective analysis of data from the national influenza surveillance system in Germany, 2012 to 2014.
ConclusionOur data are the first on influenza C virus circulation in Germany and notably from a European national surveillance system. The low detection frequency and the identified virus variants confirm earlier observations outside a surveillance system. More virus detections during the 2012/13 season indicate a variable circulation intensity in the different years studied. Influenza C virus can be considered for ILI patients. Future studies addressing its clinical impact, especially in patients with severe disease are needed. PMID: 30862333 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Fritsch A, Schweiger B, Biere B Tags: Euro Surveill Source Type: research

HEVnet: a One Health, collaborative, interdisciplinary network and sequence data repository for enhanced hepatitis E virus molecular typing, characterisation and epidemiological investigations.
Abstract Hepatitis E virus (HEV) is a common cause of acute hepatitis worldwide. In Europe, HEV is a zoonosis transmitted via contaminated pork meat or other pork food products. Genotype 3 is the most prevalent HEV type in the animal reservoir, as well as in humans. Despite an increased incidence of hepatitis E across Europe, much remains unknown about its spread, sources and transmission routes. A One Health approach is crucial to better understand the (molecular) epidemiology of HEV. HEVnet was established in April 2017 as a network and database for sharing sequences and accompanying metadata collected from huma...
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Mulder AC, Kroneman A, Franz E, Vennema H, Tulen AD, Takkinen J, Hofhuis A, Adlhoch C, Members Of HEVnet Tags: Euro Surveill Source Type: research

Increased risk of chikungunya infection in travellers to Thailand during ongoing outbreak in tourist areas: cases imported to Europe and the Middle East, early 2019.
We report nine travellers with confirmed chikungunya virus infection, returning from tourist areas of Thailand to Sweden, Switzerland, the United Kingdom, Romania, Israel and France, diagnosed in January and February 2019. These sentinel tourists support the intensification of chikungunya virus circulation in Thailand and highlight the potential for importation to areas at risk of local transmission. PMID: 30862335 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Javelle E, Florescu SA, Asgeirsson H, Jmor S, Eperon G, Leshem E, Blum J, Molina I, Field V, Pietroski N, Eldin C, Johnston V, Cotar IA, Popescu C, Hamer DH, Gautret P Tags: Euro Surveill Source Type: research

Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018.
We describe detection in the United Kingdom (UK) of the drug-resistant Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate azithromycin resistance. Two female patients developed infection following contact with UK-resident men from the same sexual network linked to travel to Ibiza, Spain. One case failed treatment with ceftriaxone, and azithromycin and gentamicin, before successful treatment with ertapenem. Both isolates had indistinguishable whole-genome sequences. Urgent action is essential to contain this drug-resistant strain. PMID: 30862336 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Eyre DW, Town K, Street T, Barker L, Sanderson N, Cole MJ, Mohammed H, Pitt R, Gobin M, Irish C, Gardiner D, Sedgwick J, Beck C, Saunders J, Turbitt D, Cook C, Phin N, Nathan B, Horner P, Fifer H Tags: Euro Surveill Source Type: research

Epidemiology and genotype 3 subtype dynamics of hepatitis E virus in Belgium, 2010 to 2017.
ConclusionThe increasing trend of HEV diagnoses in Belgium may be largely explained by increased awareness and testing. PMID: 30862337 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Suin V, Klamer SE, Hutse V, Wautier M, Jacques M, Abady M, Lamoral S, Verburgh V, Thomas I, Brochier B, Subissi L, Van Gucht S Tags: Euro Surveill Source Type: research

Hepatitis E virus in blood donors in England, 2016 to 2017: from selective to universal screening.
ConclusionHEV screening of blood donations is a vital step in order to provide safer blood for all recipients, but especially for the immunosuppressed. The unusually high rates of HEV infection in young blood donors may provide some insight into specific risks associated with HEV infection in England. PMID: 30862338 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2019 Category: Infectious Diseases Authors: Harvala H, Hewitt PE, Reynolds C, Pearson C, Haywood B, Tettmar KI, Ushiro-Lumb I, Brailsford SR, Tedder R, Ijaz S Tags: Euro Surveill Source Type: research

Call for papers for a special issue on how point of care/point of impact testing (POCT/ POIT) and self-testing impact surveillance and public health.
PMID: 30808437 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Job vacancy at the European Centre for Disease Prevention and Control.
PMID: 30808438 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Analysis of exotic squirrel trade and detection of human infections with variegated squirrel bornavirus 1, Germany, 2005 to 2018.
sit J Abstract Following the discovery in 2015 of the variegated squirrel bornavirus 1 (VSBV-1) in fatal encephalitis cases among exotic squirrel breeders and a zoo animal caretaker in Germany, a case definition was developed. It was employed during trace-back animal trade investigations and sero-epidemiological studies among breeders and zoo animal caretakers of holdings with VSBV-1 infected squirrels. During the investigation, two possible human cases who had died of encephalitis were identified retrospectively among the squirrel breeders. Moreover, one probable human case was detected among the breeders who had...
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Tappe D, Frank C, Homeier-Bachmann T, Wilking H, Allendorf V, Schlottau K, Muñoz-Fontela C, Rottstegge M, Port JR, Rissland J, Eisermann P, Beer M, Schmidt-Chanasit J Tags: Euro Surveill Source Type: research

Interim 2018/19 influenza vaccine effectiveness: six European studies, October 2018 to January 2019.
Abstract Influenza A(H1N1)pdm09 and A(H3N2) viruses both circulated in Europe in October 2018-January 2019. Interim results from six studies indicate that 2018/19 influenza vaccine effectiveness (VE) estimates among all ages in primary care was 32-43% against influenza A; higher against A(H1N1)pdm09 and lower against A(H3N2). Among hospitalised older adults, VE estimates were 34-38% against influenza A and slightly lower against A(H1N1)pdm09. Influenza vaccination is of continued benefit during the ongoing 2018/19 influenza season. PMID: 30808440 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Kissling E, Rose A, Emborg HD, Gherasim A, Pebody R, Pozo F, Trebbien R, Mazagatos C, Whitaker H, Valenciano M, European Ive Group Tags: Euro Surveill Source Type: research

Tracking Rift Valley fever: From Mali to Europe and other countries, 2016.
nti V Abstract On 16 September 2016, the World Health Organization confirmed a Rift Valley fever (RVF) outbreak in Niger. Epidemiological surveillance was reinforced among the French Armed Forces deployed in Niger and bordering countries: Chad, Mali and Burkina Faso. On 26 October, a probable case of RVF was reported in a service member sampled in Mali 3 weeks earlier. At the time the result was reported, the patient was on vacation on Martinique. An epidemiological investigation was conducted to confirm this case and identify other cases. Finally, the case was not confirmed, but three suspected cases of RVF were ...
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Tong C, Javelle E, Grard G, Dia A, Lacrosse C, Fourié T, Gravier P, Watier-Grillot S, Lancelot R, Letourneur F, Comby F, Grau M, Cassou L, Meynard JB, Briolant S, Leparc-Goffart I, Pommier de Santi V Tags: Euro Surveill Source Type: research

Paediatric haemolytic uraemic syndrome related to Shiga toxin-producing Escherichia coli, an overview of 10 years of surveillance in France, 2007 to 2016.
Surveillance du Shu Pédiatrique Abstract IntroductionHaemolytic uraemic syndrome (HUS) related to Shiga toxin-producing Escherichia coli (STEC) is the leading cause of acute renal failure in young children. In France, HUS surveillance in children aged 
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Bruyand M, Mariani-Kurkdjian P, Le Hello S, King LA, Van Cauteren D, Lefevre S, Gouali M, Jourdan-da Silva N, Mailles A, Donguy MP, Loukiadis E, Sergentet-Thevenot D, Loirat C, Bonacorsi S, Weill FX, De Valk H, Réseau Français Hospitalier de Surveillanc Tags: Euro Surveill Source Type: research

Implementation and evaluation of the human papillomavirus (HPV) vaccination pilot for men who have sex with men (MSM), England, April 2016 to March 2017.
CONCLUSION: An opportunistic HPV vaccination programme for MSM can be delivered in an acceptable and, as far as can be evaluated, equitable manner, without major disruption to SHC and HIV clinics. PMID: 30808443 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Edelstein M, Iyanger N, Hennessy N, Mesher D, Checchi M, Soldan K, McCall M, Nugent J, Crofts J, Lo J, Gilson R, Powell K, Ramsay M, Yarwood J Tags: Euro Surveill Source Type: research

No evidence of carbapenemase-producing Enterobacteriaceae in stool samples of 1,544 asylum seekers arriving in Rhineland-Palatinate, Germany, April 2016 to March, 2017.
CONCLUSION: In absence of other risk factors, being a newly arrived asylum seeker from a region with increased faecal ESBL-PE colonisation prevalence is not an indicator for C-PE colonisation and thus not a reason for pre-emptive screening and isolation upon hospital admission. PMID: 30808444 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Ehlkes L, Pfeifer Y, Werner G, Ignatius R, Vogt M, Eckmanns T, Zanger P, Walter J Tags: Euro Surveill Source Type: research

Genetic relatedness of ceftriaxone-resistant and high-level azithromycin resistant Neisseria gonorrhoeae cases, United Kingdom and Australia, February to April 2018.
Abstract Between February and April 2018, three ceftriaxone-resistant and high-level azithromycin-resistant Neisseria gonorrhoeae cases were identified; one in the United Kingdom and two in Australia. Whole genome sequencing was used to show that the isolates from these cases belong to a single gonococcal clone, which we name the A2543 clone. PMID: 30808445 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Jennison AV, Whiley D, Lahra MM, Graham RM, Cole MJ, Hughes G, Fifer H, Andersson M, Edwards A, Eyre D Tags: Euro Surveill Source Type: research

Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015.
Abstract IntroductionPertussis outbreaks have occurred in several industrialised countries using acellular pertussis vaccines (ACVs) since the 1990s. High prevalence of pertactin (PRN)-deficient Bordetella pertussis isolates has been found in these countries.AimsTo evaluate in Europe: (i) whether proportions of PRN-deficient strains increased in consecutive collections of B. pertussis clinical isolates; (ii) if the frequency of PRN-deficient strains in countries correlated with the time since ACV introduction; (iii) the presence of pertussis toxin (PT)-, filamentous haemagglutinin (FHA)- or fimbriae (Fim)-deficien...
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Barkoff AM, Mertsola J, Pierard D, Dalby T, Hoegh SV, Guillot S, Stefanelli P, van Gent M, Berbers G, Vestrheim D, Greve-Isdahl M, Wehlin L, Ljungman M, Fry NK, Markey K, He Q Tags: Euro Surveill Source Type: research

Cost-effectiveness and budget effect of pre-exposure prophylaxis for HIV-1 prevention in Germany from 2018 to 2058.
ConclusionIntroduction of PrEP in Germany is predicted to result in substantial health benefits because of reductions in HIV infections. Short-term financial investments in providing PrEP will result in substantial cost-savings in the long term. PMID: 30782266 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: van de Vijver DAMC, Richter AK, Boucher CAB, Gunsenheimer-Bartmeyer B, Kollan C, Nichols BE, Spinner CD, Wasem J, Schewe K, Neumann A Tags: Euro Surveill Source Type: research

Molecular epidemiology of an enterovirus A71 outbreak associated with severe neurological disease, Spain, 2016.
ConclusionAn emerging recombinant variant of EV-A71-C1 was responsible for the large outbreak in 2016 in Spain that was associated with many severe neurological cases. PMID: 30782267 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: González-Sanz R, Casas-Alba D, Launes C, Muñoz-Almagro C, Ruiz-García MM, Alonso M, González-Abad MJ, Megías G, Rabella N, Del Cuerpo M, Gozalo-Margüello M, González-Praetorius A, Martínez-Sapiña A, Goyanes-Galán MJ, Romero MP, Calvo C, Antón A Tags: Euro Surveill Source Type: research

Multidisciplinary, evidence-based consensus guidelines for human papillomavirus (HPV) vaccination in high-risk populations, Spain, 2016.
CONCLUSIONS: Data concerning non-routine HPV vaccination in populations with a high risk of HPV infection and associated lesions were scarce. We have developed a document to evaluate and establish evidence-based guidelines on HPV vaccination in high-risk populations in Spain, based on best available scientific evidence. PMID: 30782268 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Martínez-Gómez X, Curran A, Campins M, Alemany L, Rodrigo-Pendás JÁ, Borruel N, Castellsagué X, Díaz-de-Heredia C, Moraga-Llop FA, Del Pino M, Torné A Tags: Euro Surveill Source Type: research

Emergence of divergent enterovirus (EV) D68 sub-clade D1 strains, northern Italy, September to October 2018.
Abstract Between September and October 2018, an enterovirus D68 (EV-D68) outbreak occurred in patients hospitalised with severe acute respiratory infection in northern Italy; 21 laboratory-confirmed cases were reported. Phylogenetic analysis revealed that 16/20 of the EV-D68 sequences belonged to a divergent group within the sub-clade D1. Since its upsurge, EV-D68 has undergone rapid evolution with the emergence of new viral variants, emphasising the need for molecular surveillance that include outpatients with respiratory illness. PMID: 30782269 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Pellegrinelli L, Giardina F, Lunghi G, Uceda Renteria SC, Greco L, Fratini A, Galli C, Piralla A, Binda S, Pariani E, Baldanti F Tags: Euro Surveill Source Type: research

Genetic and antigenic characterisation of influenza A(H3N2) viruses isolated in Yokohama during the 2016/17 and 2017/18 influenza seasons.
CONCLUSION: Multiple clades, some of which differed antigenically from others, co-circulated in Yokohama, Japan during the 2016/17 and 2017/18 influenza seasons. PMID: 30755292 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Kawakami C, Yamayoshi S, Akimoto M, Nakamura K, Miura H, Fujisaki S, Pattinson DJ, Shimizu K, Ozawa H, Momoki T, Saikusa M, Yasuhara A, Usuku S, Okubo I, Toyozawa T, Sugita S, Smith DJ, Watanabe S, Kawaoka Y Tags: Euro Surveill Source Type: research

Timeliness and completeness of routine childhood vaccinations in young children residing in a district with recurrent vaccine-preventable disease outbreaks, Jerusalem, Israel.
ConclusionsConsiderable vaccination delay should be addressed within the vaccine hesitancy spectrum. Delays may induce susceptibility to vaccine-preventable disease outbreaks; tailored programmes to improve timeliness are required. PMID: 30755293 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Stein-Zamir C, Israeli A Tags: Euro Surveill Source Type: research

Childhood vaccinations: knowledge, attitudes and practices of paediatricians and factors associated with their confidence in addressing parental concerns, Italy, 2016.
ConclusionsThe majority of paediatricians in Italy are favourable to vaccination but gaps were identified between their overall positive attitudes and their knowledge, beliefs and practices. Targeted interventions are needed aimed at increasing paediatricians' confidence in addressing parents' concerns, strengthening trust towards health authorities and improving systems barriers. PMID: 30755294 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Filia A, Bella A, D'Ancona F, Fabiani M, Giambi C, Rizzo C, Ferrara L, Pascucci MG, Rota MC Tags: Euro Surveill Source Type: research

Where do Eritrean migrants get infected with malaria? The importance of considering the migration route.
PMID: 30755295 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Gautret P, Grobusch MP, Schlagenhauf P Tags: Euro Surveill Source Type: research

An increase in reports of acute flaccid paralysis (AFP) in the United Kingdom, 1 January 2018-21 January 2019: early findings.
Abstract During 2018, the United Kingdom experienced an increase in reports of cases of acute flaccid paralysis (AFP). As at 21 January 2019, 40 cases had been identified with a peak in October 2018. The increase was temporally associated with an upsurge in enterovirus (EV) D68 activity. Enterovirus was detected in 15 cases, mainly from respiratory tract samples; nine were typed as EV-D68. A national task force has been established and investigations are ongoing. PMID: 30755296 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: The United Kingdom Acute Flaccid Paralysis Afp Task Force Tags: Euro Surveill Source Type: research

Impact of rotavirus vaccination on rotavirus genotype distribution and diversity in England, September 2006 to August 2016.
ara M Abstract IntroductionRotavirus vaccination with the live-attenuated monovalent (a G1P[8] human rotavirus strain) two-dose Rotarix vaccine was introduced in England in July 2013. Since then, there have been significant reductions in rotavirus gastroenteritis incidence.AimWe assessed the vaccine's impact on rotavirus genotype distribution and diversity 3 years post-vaccine introduction.MethodsEpidemiological and microbiological data on genotyped rotavirus-positive samples between September 2006 and August 2016 were supplied by EuroRotaNet and Public Health England. Multinomial multivariable logistic regression...
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Hungerford D, Allen DJ, Nawaz S, Collins S, Ladhani S, Vivancos R, Iturriza-Gómara M Tags: Euro Surveill Source Type: research

Knowledge, attitudes and beliefs about vaccination in primary healthcare workers involved in the administration of systematic childhood vaccines, Barcelona, 2016/17.
ConclusionsDespite high reported childhood immunisation rates in Barcelona, paediatricians and paediatric nurses in PCC had vaccine doubts, especially regarding the HPV vaccine. PMID: 30755298 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - February 1, 2019 Category: Infectious Diseases Authors: Picchio CA, Carrasco MG, Sagué-Vilavella M, Rius C Tags: Euro Surveill Source Type: research

Malaria in Eritrean migrants newly arrived in seven European countries, 2011 to 2016.
This study aimed to assess malaria among Eritrean migrants in Europe from 2011 to 2016. We reviewed European migration numbers and malaria surveillance data for seven countries (Denmark, Germany, Netherlands, Norway, Sweden, Switzerland and the United Kingdom) which received 44,050 (94.3%) of 46,730 Eritreans seeking asylum in Europe in 2014. The overall number of malaria cases, predominantly P. vivax, increased significantly in 2014 compared to previous years, with the largest increases in Germany (44 P. vivax cases in 2013 vs 294 in 2014, p 
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Sondén K, Rolling T, Wångdahl A, Ydring E, Vygen-Bonnet S, Kobbe R, Douhan J, Hammar U, Duijster J, de Gier B, Freedman J, Gysin N, Stark K, Stevens F, Vestergaard LS, Tegnell A, Färnert A Tags: Euro Surveill Source Type: research

First detection of a Vssc allele V1016G conferring a high level of insecticide resistance in Aedes albopictus collected from Europe (Italy) and Asia (Vietnam), 2016: a new emerging threat to controlling arboviral diseases.
ConclusionThe V1016G allele was detected in bothAsian and Italian Ae. albopictus populations, thus a spread of this allele beyond Italy in Europe cannot be ruled out. This study emphasises the necessity to frequently and regularly monitor the V1016G allele in Ae. albopictus, particularly where this mosquito species is the main vector of arboviruses. PMID: 30722810 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Kasai S, Caputo B, Tsunoda T, Cuong TC, Maekawa Y, Lam-Phua SG, Pichler V, Itokawa K, Murota K, Komagata O, Yoshida C, Chung HH, Bellini R, Tsuda Y, Teng HJ, Filho JLL, Alves LC, Ng LC, Minakawa N, Yen NT, Phong TV, Sawabe K, Tomita T Tags: Euro Surveill Source Type: research

Laboratory management of Crimean-Congo haemorrhagic fever virus infections: perspectives from two European networks.
ConclusionNo effective vaccine and/or therapeutics are available at present so outbreak response relies on rapid identification and appropriate infection control measures. Frontline hospitals and reference laboratories have a crucial role in the response to a CCHF outbreak, which should integrate laboratory, clinical and public health responses. PMID: 30722811 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Bartolini B, Gruber CE, Koopmans M, Avšič T, Bino S, Christova I, Grunow R, Hewson R, Korukluoglu G, Lemos CM, Mirazimi A, Papa A, Sanchez-Seco MP, Sauer AV, Zeller H, Nisii C, Capobianchi MR, Ippolito G, Reusken CB, Di Caro A Tags: Euro Surveill Source Type: research

Bacterial sexually transmitted infections in France: recent trends and patients' characteristics in 2016.
This article presents recent epidemiological trends until 2016 and the patients' characteristics. STI surveillance relies on sentinel networks: a clinician-based network RésIST (clinical, biological and behavioural data for early syphilis and gonorrhoea), the lymphogranuloma venereum (LGV) network (clinical, biological and behavioural data for rectal LGV, and the laboratory networks Rénachla and Rénago (demographic and biological data for chlamydial infections and gonorrhoea, respectively). Here we describe trends between 2014 and 2016, using data from diagnostic centres which participated regularly du...
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Ndeikoundam Ngangro N, Viriot D, Fournet N, Pioche C, De Barbeyrac B, Goubard A, Dupin N, Berçot B, Fouéré S, Alcaraz I, Ohayon M, Spenatto N, Vernay-Vaisse C, Referents For The Regional Offices Of The French National Public Health Agency, Pillonel J, Tags: Euro Surveill Source Type: research

Bloodstream infections due to carbapenemase-producing Enterobacteriaceae in Italy: results from nationwide surveillance, 2014 to 2017.
Abstract Following the rapid increase of infections due to carbapenemase-producing Enterobacteriaceae (CPE) in Italy, the national surveillance of bloodstream infections (BSI) due to CPE (Klebsiella pneumoniae and Escherichia coli) was instituted in 2013. All CPE-BSI cases reported to the surveillance in the years 2014-17 were analysed in order to investigate incidence rate (IR), trend, main individual characteristics and enzymes involved in CPE resistance. Throughout this period, 7,632 CPE-BSI cases (IR: 3.14/100,000 inhabitants) were reported from all 21 regions and autonomous provinces in Italy, with an ...
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Iacchini S, Sabbatucci M, Gagliotti C, Rossolini GM, Moro ML, Iannazzo S, D'Ancona F, Pezzotti P, Pantosti A Tags: Euro Surveill Source Type: research

Early season estimate of influenza vaccination effectiveness against influenza hospitalisation in children, Hong Kong, winter influenza season 2018/19.
Abstract The winter 2018/19 influenza season in Hong Kong has been predominated by influenza A(H1N1)pdm09 as at January 2019. We enrolled 2,016 children in three public hospitals in Hong Kong between 2 September 2018 and 11 January 2019. Using the test-negative approach, we estimated high early season effectiveness of inactivated influenza vaccine against influenza A or B of 90% (95% confidence interval (CI): 80-95%) and 92% (95% CI: 82-96%) against influenza A(H1N1)pdm09. PMID: 30722814 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Chiu SS, Kwan MY, Feng S, Chan EL, Chua H, Wong JS, Peiris JM, Cowling BJ Tags: Euro Surveill Source Type: research

Applications for the 2019 ECDC traineeship programme, including at the Eurosurveillance office, open until 31 January.
PMID: 30696522 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Interim estimates of 2018/19 vaccine effectiveness against influenza A(H1N1)pdm09, Canada, January 2019.
Abstract Using a test-negative design, the Canadian Sentinel Practitioner Surveillance Network assessed interim 2018/19 vaccine effectiveness (VE) against predominant influenza A(H1N1)pdm09 viruses. Adjusted VE was 72% (95% confidence interval: 60 to 81) against medically attended, laboratory-confirmed influenza A(H1N1)pdm09 illness. This substantial vaccine protection was observed in all age groups, notably young children who appeared to be disproportionately affected. Sequence analysis identified heterogeneity in emerging clade 6B.1 viruses but no dominant drift variant. PMID: 30696523 [PubMed - in process]...
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Skowronski DM, Leir S, Sabaiduc S, Murti M, Dickinson JA, Olsha R, Gubbay JB, Croxen MA, Charest H, Chan T, Bastien N, Li Y, Krajden M, De Serres G Tags: Euro Surveill Source Type: research

How do advanced diagnostics support public health policy development?
PMID: 30696524 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Moran-Gilad J Tags: Euro Surveill Source Type: research

Review of the impact of MALDI-TOF MS in public health and hospital hygiene, 2018.
ConclusionsMALDI-TOF MS is a powerful method for protein analysis. The increase in speed of pathogen detection enables improvement of antimicrobial therapy, infection prevention and control measures leading to positive impact on public health. For antibiotic susceptibility testing and bacterial typing, it represents a rapid alternative to time-consuming conventional techniques. PMID: 30696525 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2019 Category: Infectious Diseases Authors: Rodríguez-Sánchez B, Cercenado E, Coste AT, Greub G Tags: Euro Surveill Source Type: research