Real-time monitoring shows substantial excess all-cause mortality during second wave of COVID-19 in Europe, October to December 2020.
bvos J, Paldy A, Rotem N, Kornilenko I, Domegan L, O'Donnell J, Donato F, Scortichini M, Hoffmann P, Velez T, England K, Calleja N, van Asten L, Stoeldraijer L, White RA, Paulsen TH, da Silva SP, Rodrigues AP, Klepac P, Zaletel M, Fafangel M, Larrauri A, León I, Farah A, Galanis I, Junker C, Perisa D, Sinnathamby M, Andrews N, O'Doherty MG, Irwin D, Kennedy S, McMenamin J, Adlhoch C, Bundle N, Penttinen P, Pukkila J, Pebody R, Krause TG, Mølbak K Abstract The European monitoring of excess mortality for public health action (EuroMOMO) network monitors weekly excess all-cause mortality in 27 European c...
Source: Euro Surveill - January 1, 2021 Category: Infectious Diseases Authors: Nørgaard SK, Vestergaard LS, Nielsen J, Richter L, Schmid D, Bustos N, Braye T, Athanasiadou M, Lytras T, Denissov G, Veideman T, Luomala O, Möttönen T, Fouillet A, Caserio-Schönemann C, An der Heiden M, Uphoff H, Gkolfinopoulou K, Bobvos J, Paldy A, Tags: Euro Surveill Source Type: research

Job vacancies at the European Centre for Disease Prevention and Control (ECDC).
PMID: 33413738 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2021 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Eurosurveillance reviewers in 2020.
PMID: 33413739 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2021 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Early transmissibility assessment of the N501Y mutant strains of SARS-CoV-2 in the United Kingdom, October to November 2020.
Abstract Two new SARS-CoV-2 lineages with the N501Y mutation in the receptor-binding domain of the spike protein spread rapidly in the United Kingdom. We estimated that the earlier 501Y lineage without amino acid deletion Δ69/Δ70, circulating mainly between early September and mid-November, was 10% (6-13%) more transmissible than the 501N lineage, and the 501Y lineage with amino acid deletion Δ69/Δ70, circulating since late September, was 75% (70-80%) more transmissible than the 501N lineage. PMID: 33413740 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2021 Category: Infectious Diseases Authors: Leung K, Shum MH, Leung GM, Lam TT, Wu JT Tags: Euro Surveill Source Type: research

Impact of mass testing during an epidemic rebound of SARS-CoV-2: a modelling study using the example of France.
Abstract We used a mathematical model to evaluate the impact of mass testing in the control of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Under optimistic assumptions, one round of mass testing may reduce daily infections by up to 20-30%. Consequently, very frequent testing would be required to control a quickly growing epidemic if other control measures were to be relaxed. Mass testing is most relevant when epidemic growth remains limited through a combination of interventions. PMID: 33413741 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2021 Category: Infectious Diseases Authors: Bosetti P, Kiem CT, Yazdanpanah Y, Fontanet A, Lina B, Colizza V, Cauchemez S Tags: Euro Surveill Source Type: research

Control of a COVID-19 outbreak in a nursing home by general screening and cohort isolation in Germany, March to May 2020.
Abstract Elderly care facilities have become a major focus of coronavirus disease (COVID-19) control. Here, we describe an outbreak of COVID-19 in a nursing home in Germany from 8 March to 4 May 2020 (58 days), and the effect of an intervention of general screening and cohort isolation. COVID-19 cases among residents and staff were recorded on a daily basis from the first positive SARS-CoV-2 test from a resident on 8 March 2020, until 4 May 2020 when the last staff member was classified COVID-19 negative. Eighty of 160 residents (50%) and 37 of 135 staff members (27%) tested positive for SARS-CoV-2. Twenty-seven o...
Source: Euro Surveill - January 1, 2021 Category: Infectious Diseases Authors: Krone M, Noffz A, Richter E, Vogel U, Schwab M Tags: Euro Surveill Source Type: research

Minimal transmission of SARS-CoV-2 from paediatric COVID-19 cases in primary schools, Norway, August to November 2020.
e BA Abstract An intense debate on school closures to control the COVID-19 pandemic is ongoing in Europe. We prospectively examined transmission of SARS-CoV-2 from confirmed paediatric cases in Norwegian primary schools between August and November 2020. All in-school contacts were systematically tested twice during their quarantine period. With preventive measures implemented in schools, we found minimal child-to-child (0.9%, 2/234) and child-to-adult (1.7%, 1/58) transmission, supporting that under 14 year olds are not the drivers of SARS-CoV-2 transmission. PMID: 33413743 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - January 1, 2021 Category: Infectious Diseases Authors: Brandal LT, Ofitserova TS, Meijerink H, Rykkvin R, Lund HM, Hungnes O, Greve-Isdahl M, Bragstad K, Nygård K, Winje BA Tags: Euro Surveill Source Type: research

Occupation- and age-associated risk of SARS-CoV-2 test positivity, the Netherlands, June to October 2020.
e; SJ Abstract High coronavirus incidence has prompted the Netherlands to implement a second lockdown. To elucidate the epidemic's development preceding this second wave, we analysed weekly test positivity in public test locations by population subgroup between 1 June and 17 October 2020. Hospitality and public transport workers, driving instructors, hairdressers and aestheticians had higher test positivity compared with a reference group of individuals without a close-contact occupation. Workers in childcare, education and healthcare showed lower test positivity. PMID: 33334396 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: de Gier B, de Oliveira Bressane Lima P, van Gaalen RD, de Boer PT, Alblas J, Ruijten M, van Gageldonk-Lafeber AB, Waegemaekers T, Schreijer A, van den Hof S, Hahné SJ Tags: Euro Surveill Source Type: research

Evaluation of lockdown effect on SARS-CoV-2 dynamics through viral genome quantification in waste water, Greater Paris, France, 5 March to 23 April 2020.
ConclusionThis work suggests that a quantitative monitoring of SARS-CoV-2 genomes in WW could generate important additional information for improved monitoring of SARS-CoV-2 circulation at local or regional levels and emphasises the role of WW-based epidemiology. PMID: 33334397 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Wurtzer S, Marechal V, Mouchel JM, Maday Y, Teyssou R, Richard E, Almayrac JL, Moulin L Tags: Euro Surveill Source Type: research

Estimating the false-negative test probability of SARS-CoV-2 by RT-PCR.
l;o J Abstract BackgroundReverse-transcription PCR (RT-PCR) assays are used to test for infection with the SARS-CoV-2 virus. RT-PCR tests are highly specific and the probability of false positives is low, but false negatives are possible depending on swab type and time since symptom onset.AimTo determine how the probability of obtaining a false-negative test in infected patients is affected by time since symptom onset and swab type.MethodsWe used generalised additive mixed models to analyse publicly available data from patients who received multiple RT-PCR tests and were identified as SARS-CoV-2 positive at least ...
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Wikramaratna PS, Paton RS, Ghafari M, Lourenço J Tags: Euro Surveill Source Type: research

Early assessment of the impact of mitigation measures to control COVID-19 in 22 French metropolitan areas, October to November 2020.
This study descriptively assesses their possible effects, also relative to their timing. A considerable decrease in incidence of COVID-19 cases and hospital admissions was observed 7 to 10 days after mitigation measures were put in place, occurring earlier in metropolitan areas which had implemented these first. This temporal coincidence suggests the measures' positive impact, consistent with international experiences. PMID: 33334399 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Spaccaferri G, Larrieu S, Pouey J, Calba C, Benet T, Sommen C, Lévy-Bruhl D, Smaili S, Che D, Filleul L, Caserio-Schönemann C, Ait-El-Belghiti F, Haeghebaert S, Desenclos JC, Huiart L, Laporte A, Rolland P Tags: Euro Surveill Source Type: research

The first wave of the COVID-19 pandemic in Spain: characterisation of cases and risk factors for severe outcomes, as at 27 April 2020.
ConclusionsCOVID-19 case numbers began declining 6 days after the national lockdown. The first wave of the COVID-19 pandemic in Spain had a severe impact on elderly people. Patients with cardiovascular or renal conditions were at higher risk for severe outcomes. A high proportion of cases were HCWs. Enhanced surveillance and control measures in these subgroups are crucial during future COVID-19 waves. PMID: 33334400 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Working group for the surveillance and control of COVID-19 in Spain, Members of the Working group for the surveillance and control of COVID-19 in Spain Tags: Euro Surveill Source Type: research

Face masks and COVID-19: don't let perfect be the enemy of good.
PMID: 33303063 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Cowling BJ, Leung GM Tags: Euro Surveill Source Type: research

Epidemiological characteristics of COVID-19 cases and estimates of the reproductive numbers 1 month into the epidemic, Italy, 28 January to 31 March 2020.
ConclusionThe COVID-19 outbreak in Italy showed a clustering onset similar to the one in Wuhan, China. R0 at 2.96 in Lombardy combined with delayed detection explains the high case load and rapid geographical spread. Overall, Rt in Italian regions showed early signs of decrease, with large diversity in incidence, supporting the importance of combined non-pharmacological control measures. PMID: 33303064 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Riccardo F, Ajelli M, Andrianou XD, Bella A, Del Manso M, Fabiani M, Bellino S, Boros S, Urdiales AM, Marziano V, Rota MC, Filia A, D'Ancona F, Siddu A, Punzo O, Trentini F, Guzzetta G, Poletti P, Stefanelli P, Castrucci MR, Ciervo A, Di Benedetto C, Tall Tags: Euro Surveill Source Type: research

Secondary transmission of COVID-19 in preschool and school settings in northern Italy after their reopening in September 2020: a population-based study.
We report epidemiological investigations of transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 41 classes of 36 schools in Reggio Emilia province, northern Italy, from their reopening on 1 September to 15 October 2020. The overall secondary case attack rate was 3.2%, reaching 6.6% in middle and high schools. More timely isolation and testing of classmates could be effective in reducing virus transmission in this setting. PMID: 33303065 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Larosa E, Djuric O, Cassinadri M, Cilloni S, Bisaccia E, Vicentini M, Venturelli F, Giorgi Rossi P, Pezzotti P, Bedeschi E, Reggio Emilia Covid-19 Working Group Tags: Euro Surveill Source Type: research

Community use of face masks and similar barriers to prevent respiratory illness such as COVID-19: a rapid scoping review.
ConclusionWearing face masks may reduce primary respiratory infection risk, probably by 6-15%. It is important to balance evidence from RCTs and observational studies when their conclusions widely differ and both are at risk of significant bias. COVID-19-specific studies are required. PMID: 33303066 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Brainard J, Jones NR, Lake IR, Hooper L, Hunter PR Tags: Euro Surveill Source Type: research

Extremely drug-resistant NDM-9-producing ST147 Klebsiella pneumoniae causing infections in Italy, May 2020.
Abstract A large outbreak of New Delhi metallo-beta-lactamase (NDM)-1-producing Klebsiella pneumoniae sequence type (ST) 147 occurred in Tuscany, Italy in 2018-2019. In 2020, ST147 NDM-9-producing K. pneumoniae were detected at the University Hospital of Pisa, Tuscany, in two critically ill patients; one developed bacteraemia. Genomic and phylogenetic analyses suggest relatedness of 2018-2019 and 2020 strains, with a change from NDM-1 to NDM-9 in the latter and evolution by colistin, tigecycline and fosfomycin resistance acquisition. PMID: 33272354 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Falcone M, Giordano C, Barnini S, Tiseo G, Leonildi A, Malacarne P, Menichetti F, Carattoli A Tags: Euro Surveill Source Type: research

Clinical characteristics and risk factors associated with severe COVID-19: prospective analysis of 1,045 hospitalised cases in North-Eastern France, March 2020.
ConclusionsOverweightedness, obesity, advanced age, male sex, comorbidities, dyspnoea and inflammation are risk factors for severe COVID-19 or death in hospitalised patients. Identifying these features among patients in routine clinical practice might improve COVID-19 management. PMID: 33272355 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Kaeuffer C, Le Hyaric C, Fabacher T, Mootien J, Dervieux B, Ruch Y, Hugerot A, Zhu YJ, Pointurier V, Clere-Jehl R, Greigert V, Kassegne L, Lefebvre N, Gallais F, Covid Alsace Study Group, Meyer N, Hansmann Y, Hinschberger O, Danion F, COVID Alsace Study G Tags: Euro Surveill Source Type: research

Editorial note.
PMID: 33272356 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Association between SARS-CoV-2 infection and Kawasaki-like multisystem inflammatory syndrome: a retrospective matched case-control study, Paris, France, April to May 2020.
en JF Abstract We assessed the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and Kawasaki disease (KD)-like multisystem inflammatory syndrome in a retrospective case-control study in France. RT-PCR and serological tests revealed SARS-CoV-2 infection in 17/23 cases vs 11/102 controls (matched odds ratio: 26.4; 95% confidence interval: 6.0-116.9), indicating strong association between SARS-CoV-2 infection and KD-like illness. Clinicians should keep a high level of suspicion for KD-like illness during the COVID-19 pandemic. PMID: 33272357 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - December 1, 2020 Category: Infectious Diseases Authors: Toubiana J, Levy C, Allali S, Jung C, Leruez-Ville M, Varon E, Bajolle F, Ouldali N, Chareyre J, Béchet S, Elbez A, Casanova JL, Chalumeau M, Cohen R, Cohen JF Tags: Euro Surveill Source Type: research

Serology- and PCR-based cumulative incidence of SARS-CoV-2 infection in adults in a successfully contained early hotspot (CoMoLo study), Germany, May to June 2020.
e L, Wieler LH, CoMoLo Study Group, Lampert T Abstract Three months after a coronavirus disease (COVID-19) outbreak in Kupferzell, Germany, a population-based study (n = 2,203) found no RT-PCR-positives. IgG-ELISA seropositivity with positive virus neutralisation tests was 7.7% (95% confidence interval (CI): 6.5-9.1) and 4.3% with negative neutralisation tests. We estimate 12.0% (95% CI: 10.4-14.0%) infected adults (24.5% asymptomatic), six times more than notified. Full hotspot containment confirms the effectiveness of prompt protection measures. However, 88% naïve adults are still at high COVI...
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Santos-Hövener C, Neuhauser HK, Rosario AS, Busch M, Schlaud M, Hoffmann R, Gößwald A, Koschollek C, Hoebel J, Allen J, Haack-Erdmann A, Brockmann S, Ziese T, Nitsche A, Michel J, Haller S, Wilking H, Hamouda O, Corman VM, Drosten C, Schaade L, Wieler Tags: Euro Surveill Source Type: research

Impact of the COVID-19 pandemic on testing services for HIV, viral hepatitis and sexually transmitted infections in the WHO European Region, March to August 2020.
We present preliminary results of a coronavirus disease (COVID-19) impact assessment on testing for HIV, viral hepatitis and sexually transmitted infections in the WHO European Region. We analyse 98 responses from secondary care (n = 36), community testing sites (n = 52) and national level (n = 10). Compared to pre-COVID-19, 95% of respondents report decreased testing volumes during March-May and 58% during June-August 2020. Reasons for decreases and mitigation measures were analysed. PMID: 33243354 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Simões D, Stengaard AR, Combs L, Raben D, EuroTEST COVID-19 impact assessment consortium of partners Tags: Euro Surveill Source Type: research

Where has all the influenza gone? The impact of COVID-19 on the circulation of influenza and other respiratory viruses, Australia, March to September 2020.
Abstract The coronavirus disease pandemic was declared in March 2020, as the southern hemisphere's winter approached. Australia expected co-circulation of severe acute respiratory syndrome coronavirus 2, influenza and other seasonal respiratory viruses. However, influenza notifications were 7,029 (March-September) compared with an average 149,832 for the same period in 2015-2109, despite substantial testing. Restrictions on movement within and into Australia may have temporarily eliminated influenza. Other respiratory pathogens also showed remarkably changed activity in 2020. PMID: 33243355 [PubMed - in proce...
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Sullivan SG, Carlson S, Cheng AC, Chilver MB, Dwyer DE, Irwin M, Kok J, Macartney K, MacLachlan J, Minney-Smith C, Smith D, Stocks N, Taylor J, Barr IG Tags: Euro Surveill Source Type: research

Epidemiology and public health response in early phase of COVID-19 pandemic, Veneto Region, Italy, 21 February to 2 April 2020.
ConclusionIn the Veneto Region, the strict social distancing measures imposed by the Italian government were supported by thorough case finding and contact tracing, as well as well-defined roles for different levels of care. PMID: 33243356 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Russo F, Pitter G, Da Re F, Tonon M, Avossa F, Bellio S, Fedeli U, Gubian L, Monetti D, Saia M, Zanella F, Zorzi M, Narne E, Mantoan D Tags: Euro Surveill Source Type: research

Author's correction for Euro Surveill. 2020;25(45).
PMID: 33213682 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Virological surveillance of influenza viruses in the WHO European Region in 2019/20 - impact of the COVID-19 pandemic.
Abstract The COVID-19 pandemic negatively impacted the 2019/20 WHO European Region influenza surveillance. Compared with previous 4-year averages, antigenic and genetic characterisations decreased by 17% (3,140 vs 2,601) and 24% (4,474 vs 3,403). Of subtyped influenza A viruses, 56% (26,477/47,357) were A(H1)pdm09, 44% (20,880/47,357) A(H3). Of characterised B viruses, 98% (4,585/4,679) were B/Victoria. Considerable numbers of viruses antigenically differed from northern hemisphere vaccine components. In 2020/21, maintaining influenza virological surveillance, while supporting SARS-CoV-2 surveillance is crucial. ...
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Melidou A, Pereyaslov D, Hungnes O, Prosenc K, Alm E, Adlhoch C, Fielding J, Sneiderman M, Martinuka O, Celentano LP, Pebody R, WHO European Region influenza surveillance network, WHO European Region Influenza Surveillance Network author list Tags: Euro Surveill Source Type: research

West Nile virus keeps on moving up in Europe.
PMID: 33213684 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Bakonyi T, Haussig JM Tags: Euro Surveill Source Type: research

Emergence of carbapenem-resistant ST131 Escherichia coli carrying bla OXA-244 in Germany, 2019 to 2020.
We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely. PMID: 33213685 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Welker S, Boutin S, Miethke T, Heeg K, Nurjadi D Tags: Euro Surveill Source Type: research

Autochthonous West Nile virus infection outbreak in humans, Leipzig, Germany, August to September 2020.
bert UG Abstract Following a distinct summer heat wave, nine autochthonous cases of West Nile fever and West Nile neuroinvasive disease, including one fatality, were observed in Leipzig, Germany, in August and September 2020. Phylogenetic analysis demonstrated close relationships in viruses from humans, animals and mosquitos in eastern Germany, obtained during the preceding 2 years. The described large cluster of autochthonous West Nile virus infections in Germany indicates endemic seasonal circulation of lineage 2 viruses in the area. PMID: 33213686 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Pietsch C, Michalski D, Münch J, Petros S, Bergs S, Trawinski H, Lübbert C, Liebert UG Tags: Euro Surveill Source Type: research

First autochthonous human West Nile virus infections in the Netherlands, July to August 2020.
Abstract In October 2020, the first case of autochthonous West Nile virus neuroinvasive disease was diagnosed in the Netherlands with a presumed infection in the last week of August. Investigations revealed five more cases of local West Nile virus (WNV) infection. The cases resided in a region where WNV was detected in a bird and mosquitoes in August 2020. Molecular analysis was successful for two cases and identified the presence of WNV lineage 2. PMID: 33213687 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Vlaskamp DR, Thijsen SF, Reimerink J, Hilkens P, Bouvy WH, Bantjes SE, Vlaminckx BJ, Zaaijer H, van den Kerkhof HH, Raven SF, Reusken CB Tags: Euro Surveill Source Type: research

Characterising West Nile virus epidemiology in Israel using a transmission suitability index.
ConclusionsBy producing a detailed geotemporal estimate of transmission potential and its determinants in Israel, our study promotes a better understanding of WNV epidemiology and has the potential to inform future public health responses. The proposed approach further provides opportunities for retrospective and prospective mechanistic modelling of WNV epidemiology and its associated climatic drivers. PMID: 33213688 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Lourenço J, Thompson RN, Thézé J, Obolski U Tags: Euro Surveill Source Type: research

Job vacancy at the European Centre for Disease Prevention and Control (ECDC).
PMID: 33183402 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Will coronavirus disease (COVID-19) have an impact on antimicrobial resistance?
PMID: 33183403 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Monnet DL, Harbarth S Tags: Euro Surveill Source Type: research

Note from the editors: Eurosurveillance contributor survey results.
PMID: 33183405 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Enabling appropriate use of antibiotics: review of European Union procedures of harmonising product information, 2007 to 2020.
ConclusionOur findings highlight the importance of the regulatory actions. The changes made in the product information aim to ensure appropriate use. Ongoing harmonisation activities are likely to lead to further refinements and restrictions on individual antibiotics in support of rational use. However, further research is required to examine the impact of post-referral label changes on the clinical practice. PMID: 33183406 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Opalska A, Kwa M, Leufkens H, Gardarsdottir H Tags: Euro Surveill Source Type: research

Epidemiological situation, laboratory capacity and preparedness for carbapenem-resistant Acinetobacter baumannii in Europe, 2019.
obacter baumannii capacity survey group Abstract To update information on the epidemiological situation and national capacity for detection, surveillance and containment of carbapenem-resistant Acinetobacter baumannii (CRAb) in Europe, we performed a survey in 37 countries. Nine countries reported regional or inter-regional spread and seven an endemic situation. Laboratories with a reference function, surveillance systems, and a national containment plan for CRAb existed in 30, 23 and eight countries, respectively. A pan-European molecular survey would provide in-depth understanding of the CRAb epidemiology. ...
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Lötsch F, Albiger B, Monnet DL, Struelens MJ, Seifert H, Kohlenberg A, European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) carbapenem-resistant Acinetobacter baumannii capacity survey group, EURGen-Net carbapenem-resistant Acinetoba Tags: Euro Surveill Source Type: research

Rates of increase of antibiotic resistance and ambient temperature in Europe: a cross-national analysis of 28 countries between 2000 and 2016.
ConclusionWe found evidence of a long-term effect of ambient minimum temperature on antibiotic resistance rate increases in Europe. Ambient temperature might considerably influence antibiotic resistance growth rates, and explain geographic differences observed in cross-sectional studies. Rising temperatures globally may hasten resistance spread, complicating mitigation efforts. PMID: 33183408 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: McGough SF, MacFadden DR, Hattab MW, Mølbak K, Santillana M Tags: Euro Surveill Source Type: research

Erratum for Euro Surveill. 2020;25(43).
PMID: 33183409 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Effects of primary care C-reactive protein point-of-care testing on antibiotic prescribing by general practice staff: pragmatic randomised controlled trial, England, 2016 and 2017.
ConclusionsIn routine general practice, CRP POCT use was variable. Non-significant reductions in antibiotic prescribing may reflect small sample size due to non-use of tests. While CRP POCT may be useful, primary care staff need clearer CRP guidance and action planning according to NICE guidance. PMID: 33153517 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Eley CV, Sharma A, Lee H, Charlett A, Owens R, McNulty CAM Tags: Euro Surveill Source Type: research

Point-of-care tests for influenza A and B viruses and RSV in emergency departments - indications, impact on patient management and possible gains by syndromic respiratory testing, Capital Region, Denmark, 2018.
Abstract BackgroundPoint-of-care tests (POCT) for influenza A and B viruses and respiratory syncytial virus (RSV) were implemented in emergency departments of all hospitals in the Capital Region of Denmark in 2018.AimTo establish whether POC testing for influenza viruses or RSV is based on a valid respiratory symptom indication, whether changes in patient management based on a positive result are safe and whether syndromic POC testing may benefit patients with influenza or RSV.MethodsSamples from 180 children (
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Schneider UV, Holm MKA, Bang D, Petersen RF, Mortensen S, Trebbien R, Lisby JG Tags: Euro Surveill Source Type: research

The experience of point-of-care testing for influenza in Scotland in 2017/18 and 2018/19 - no gain without pain.
ConclusionThis study has shown an improvement in capture of data from influenza mPOCT and has highlighted issues that need to be addressed for results to be accurately captured in national surveillance. With the clear benefit to patient management we suggest careful consideration should be given to the connectivity aspects of the technology in order to ensure minimal impact on national surveillance. PMID: 33153519 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Dickson EM, Marques DF, Currie S, Little A, Mangin K, Coyne M, Reynolds A, McMenamin J, Yirrell D Tags: Euro Surveill Source Type: research

Job vacancies at the European Centre for Disease Prevention and Control (ECDC).
PMID: 33153520 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

The cat is out of the bag - point-of-care testing (POCT) is here to stay.
PMID: 33153521 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Phin N, Poutanen SM Tags: Euro Surveill Source Type: research

Do point-of-care tests (POCTs) offer a new paradigm for the management of patients with influenza?
Abstract The introduction of point-of-care tests (POCTs) has presented new opportunities for the management of patients presenting to healthcare providers with acute respiratory symptoms. This Perspective article is based on the experiences of national infection teams/those managing acute respiratory infections across the United Kingdom in terms of the challenges and opportunities that this may present for public health. This Perspective article was conceived and written pre-coronavirus disease (COVID-19), however the principles we outline here for influenza can also be translated to COVID-19 and some key points a...
Source: Euro Surveill - November 1, 2020 Category: Infectious Diseases Authors: Dickson EM, Zambon M, Pebody R, de Lusignan S, Elliot AJ, Ellis J, Lackenby A, Smith G, McMenamin J Tags: Euro Surveill Source Type: research

Author's correction for Euro Surveill. 2020;25(35).
PMID: 33124549 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2020 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Author's correction for Euro Surveill. 2020;25(40).
PMID: 33124550 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2020 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Using rapid point-of-care tests to inform antibiotic choice to mitigate drug resistance in gonorrhoea.
ConclusionMutation frequencies and rates should be considered when estimating the POCT usage required to reduce the risk of resistance development in a given population. Molecular POCTs for resistance mutations and stepping-stone mutations to resistance are likely to become important tools in antibiotic stewardship. PMID: 33124551 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2020 Category: Infectious Diseases Authors: Vegvari C, Grad YH, White PJ, Didelot X, Whittles LK, Scangarella-Oman NE, Mitrani-Gold FS, Dumont E, Perry CR, Gilchrist K, Hossain M, Mortimer TD, Anderson RM, Gardiner D Tags: Euro Surveill Source Type: research

The contribution of HIV point-of-care tests in early HIV diagnosis: community-based HIV testing monitoring in Catalonia, 1995 to 2018.
ConclusionOur study reinforces the important role that community-based HIV POCT has on the diagnosis of HIV in key populations. PMID: 33124552 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2020 Category: Infectious Diseases Authors: Fernàndez-López L, Reyes-Urueña J, Conway A, Saz J, Morales A, Quezadas J, Baroja J, Rafel A, Pazos A, Avellaneda A, Meroño M, Andreo L, Romero L, Lara A, Otón A, Rifà B, Mansilla R, Colom J, Casabona J Tags: Euro Surveill Source Type: research

Antimicrobial resistance point-of-care testing for gonorrhoea treatment regimens: cost-effectiveness and impact on ceftriaxone use of five hypothetical strategies compared with standard care in England sexual health clinics.
ConclusionsAMR POCT may enable improved antibiotic stewardship, but require net health system investment. A small reduction in test cost would enable monotherapy AMR POCT strategies to be cost-saving. PMID: 33124553 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2020 Category: Infectious Diseases Authors: Harding-Esch EM, Huntington SE, Harvey MJ, Weston G, Broad CE, Adams EJ, Sadiq ST Tags: Euro Surveill Source Type: research

Retrospective analysis on confirmation rates for referred positive rotavirus samples in England, 2016 to 2017: implications for diagnosis and surveillance.
ConclusionsThis report highlights high false positive rates with the most commonly used RV screening tests and emphasises the importance of implementing verified confirmatory tests for RV detections. This has implications for clinical diagnosis and national surveillance. PMID: 33124554 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2020 Category: Infectious Diseases Authors: Celma CC, Beard S, Douglas A, Wong S, Osafo NK, Hannah M, Hale A, Huggins G, Ladhani S, Dunning J Tags: Euro Surveill Source Type: research