Erratum for Euro Surveill. 2018;23(20).
PMID: 29871719 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Travel-associated hepatitis A in Europe, 2009 to 2015.
The objective of this study was to estimate the risk for hepatitis A among European travellers using surveillance and travel denominator data. Methods: We retrieved hepatitis A surveillance data from 13 European Union (EU)/ European Economic Area (EEA) countries with comprehensive surveillance systems and travel denominator data from the Statistical Office of the European Union. A travel-associated case of hepatitis A was defined as any case reported as imported. Results: From 2009 to 2015, the 13 countries reported 18,839 confirmed cases of hepatitis A, of which 5,233 (27.8%) were travel-associated. Of these...
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Beauté J, Westrell T, Schmid D, Müller L, Epstein J, Kontio M, Couturier E, Faber M, Mellou K, Borg ML, Friesema I, Vold L, Severi E Tags: Euro Surveill Source Type: research

Introduction of new and reinforcement of existing compulsory vaccinations in Italy: first evaluation of the impact on vaccination coverage in 2017.
Abstract In June 2017, a decree-law to increase the number of mandatory vaccinations from 4 to 10 for minors up to 16-years-old was issued in Italy. The vaccination coverage for 2017 showed a positive impact for all the vaccines, particularly for the measles, mumps and rubella vaccine at 91.6% for the year 2017, showing a 4.4% increase compared with 2016 (87.2%). Continued monitoring is needed to evaluate the medium to long-term effects of the law. PMID: 29871721 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: D'Ancona F, D'Amario C, Maraglino F, Rezza G, Ricciardi W, Iannazzo S Tags: Euro Surveill Source Type: research

Vector competence of Aedes albopictus for the Indian Ocean lineage (IOL) chikungunya viruses of the 2007 and 2017 outbreaks in Italy: a comparison between strains with and without the E1:A226V mutation.
Abstract We compared the vector competence of an Italian population of Aedes albopictus for two strains of chikungunya virus (CHIKV), with and without E1:A226V mutation, responsible for outbreaks in 2007 in the Emilia Romagna region and 2017 in the Lazio and Calabria regions, respectively. Ae. albopictus showed similar vector competence for both viral strains indicating that E1:A226V mutation is not exclusively responsible for ability of CHIKV to replicate well in this mosquito species. PMID: 29871722 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Fortuna C, Toma L, Remoli ME, Amendola A, Severini F, Boccolini D, Romi R, Venturi G, Rezza G, Di Luca M Tags: Euro Surveill Source Type: research

Hepatitis A: an epidemiological survey in blood donors, France 2015 to 2017.
Abstract Since mid-2016, hepatitis A virus (HAV) outbreaks, involving predominantly men who have sex with men (MSM), have affected countries in Europe and overseas. In France, HAV screening of blood donations in 2017 revealed a HAV-RNA prevalence ca fivefold higher than during 2015-16 (4.42/106 vs 0.86/106; p = 0.0005). In 2017, despite a higher male-to-female ratio (5.5 vs 0.7) and the identification of MSM-associated outbreak strains, only one of 11 infected male donors self-reported being a MSM. PMID: 29845926 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Gallian P, Barlet V, Mouna L, Gross S, Lecam S, Ricard C, Wind F, Pouchol E, Fabra C, Flan B, Visse C, Djoudi R, Couturier E, de Valk H, Tiberghien P, Roque-Afonso AM Tags: Euro Surveill Source Type: research

Yellow fever in two unvaccinated French tourists to Brazil, January and March, 2018.
We report two yellow fever cases in unvaccinated French travellers in Brazil in January and March 2018, respectively; one exposed during an excursion in Minas Gerais and the other in Ilha Grande. Both presented with fever, hepatitis, thrombocytopenia and leucopenia. Yellow fever diagnosis was based on RT-PCR and serological tests. Both patients recovered within a few days. The increasing occurrence of cases in unvaccinated travellers highlights the need to reinforce vaccination recommendation for travellers at-risk. PMID: 29845927 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Oliosi E, Serero Corcos C, Barroso PF, Bleibtreu A, Grard G, De Filippis BAM, Caumes E Tags: Euro Surveill Source Type: research

Multidrug-resistant Neisseria gonorrhoeae failing treatment with ceftriaxone and doxycycline in France, November 2017.
We report a multidrug-resistant Neisseria gonorrhoeae urogenital and pharyngeal infection with ceftriaxone resistance and intermediate resistance to azithromycin in a heterosexual woman in her 20s in France. Treatment with ceftriaxone plus doxycycline failed for the pharyngeal localisation. Whole-genome sequencing of isolate F90 identified MLST1903, NG-MAST ST3435, NG-STAR233, and relevant resistance determinants. F90 showed phenotypic and genotypic similarities to an internationally spreading multidrug-resistant and ceftriaxone-resistant clone detected in Japan and subsequently in Australia, Canada and Denmark. PMID:...
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Poncin T, Fouere S, Braille A, Camelena F, Agsous M, Bebear C, Kumanski S, Lot F, Mercier-Delarue S, Ngangro NN, Salmona M, Schnepf N, Timsit J, Unemo M, Bercot B Tags: Euro Surveill Source Type: research

Process and outcome indicators for infection control and prevention in European acute care hospitals in 2011 to 2012 - Results of the PROHIBIT study.
Discussion/conclusion: Objectives and methods of surveillance vary across Europe, with BSI, SSI and MRSA receiving considerably more attention than indicators such as pneumonia and urinary tract infection, which may be equally important. In order to maximise prevention and control of HCAI and MDRO in Europe, surveillance should be further improved by targeting relevant HCAI. The role of feedback should be explored in more detail. PMID: 29845929 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Hansen S, Schwab F, Zingg W, Gastmeier P, The Prohibit Study Group Tags: Euro Surveill Source Type: research

Increasing macrolide resistance among Streptococcus agalactiae causing invasive disease in non-pregnant adults was driven by a single capsular-transformed lineage, Portugal, 2009 to 2015.
tions Abstract We characterised Lancefield group B streptococcal (GBS) isolates causing invasive disease among non-pregnant adults in Portugal between 2009 and 2015. All isolates (n = 555) were serotyped, assigned to clonal complexes (CCs) by multilocus sequence typing and characterised by surface protein and pilus island gene profiling. Antimicrobial susceptibility was tested by disk diffusion and resistance genotypes identified by PCR. Overall, serotype Ia was most frequent in the population (31%), followed by serotypes Ib (24%) and V (18%). Serotype Ib increased significantly throughout the study period (p 
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Lopes E, Fernandes T, Machado MP, Carriço JA, Melo-Cristino J, Ramirez M, Martins ER, The Portuguese Group For The Study Of Streptococcal Infections Tags: Euro Surveill Source Type: research

Persistent disparities in antiretroviral treatment (ART) coverage and virological suppression across Europe, 2004 to 2015.
e EuroSIDA Study Group Abstract BACKGROUND: Direct comparisons between countries in core HIV care parameters are often hampered by differences in data collection. AIM: Within the EuroSIDA study, we compared levels of antiretroviral treatment (ART) coverage and virological suppression (HIV RNA 
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Laut K, Shepherd L, Radoi R, Karpov I, Parczewski M, Mussini C, Maltez F, Losso M, Chkhartishvili N, Elinav H, Kovari H, Blaxhult A, Zangerle R, Trofimova T, Inglot M, Zilmer K, Kuzovatova E, Staub T, Raben D, Lundgren J, Mocroft A, Kirk O, On Behalf Of T Tags: Euro Surveill Source Type: research

Establishment of the European meningococcal strain collection genome library (EMSC-GL) for the 2011 to 2012 epidemiological year.
agi M, Maiden MC, Caugant DA Abstract Invasive meningococcal disease surveillance in Europe combines isolate characterisation and epidemiological data to support public health intervention. A representative European Meningococcal Strain Collection (EMSC) of IMD isolates was obtained, and whole genome sequenced to characterise 799 EMSC isolates from the epidemiological year July 2011-June 2012. To establish a genome library (GL), the isolate information was deposited in the pubMLST.org/neisseria database. Genomes were curated and annotated at 2,429 meningococcal loci, including those defining clonal complex, capsul...
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Bratcher HB, Brehony C, Heuberger S, Pieridou-Bagatzouni D, Křížová P, Hoffmann S, Toropainen M, Taha MK, Claus H, Tzanakaki G, Erdôsi T, Galajeva J, van der Ende A, Skoczyńska A, Pana M, Vaculíková A, Paragi M, Maiden MC, Caugant DA Tags: Euro Surveill Source Type: research

Measles outbreak in a tertiary level hospital, Porto, Portugal, 2018: challenges in the post-elimination era.
nes D Abstract A measles outbreak has been occurring in a healthcare setting in Porto, Portugal, since early March 2018, posing public health challenges for a central hospital and the community. Up to 22 April, 96 cases were confirmed, 67 in vaccinated healthcare workers, mostly between 18-39 years old. Following identification of the first cases, control measures were rapidly implemented. Concomitantly, other measles cases were notified in the Northern Region of the country. No common epidemiological link was identified. PMID: 29790461 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Sá Machado R, Perez Duque M, Almeida S, Cruz I, Sottomayor A, Almeida I, R Oliveira J, Antunes D Tags: Euro Surveill Source Type: research

Negligible import of enteric pathogens by newly-arrived asylum seekers and no impact on incidence of notified Salmonella and Shigella infections and outbreaks in Rhineland-Palatinate, Germany, January 2015 to May 2016.
Conclusion: Public health risk associated with imported enteric pathogens is very low overall. Addressing individual and public health risks, we recommend replacing stool screening of all newly-arrived asylum seekers by a targeted approach, with target groups and approaches being adapted if necessary. Target groups supported by our data are children, adolescents, and Eritreans. PMID: 29790462 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Ehlkes L, George M, Knautz D, Burckhardt F, Jahn K, Vogt M, Zanger P Tags: Euro Surveill Source Type: research

Status, quality and specific needs of Ebola virus diagnostic capacity and capability in laboratories of the two European preparedness laboratory networks EMERGE and EVD-LabNet.
s M Abstract From December 2013 to March 2016, West Africa experienced the largest Ebola virus (EBOV) outbreak to date, leading to a European-wide activation of laboratory preparedness and response. At the end of the outbreak, laboratories associated with the two European preparedness networks of expert laboratories EMERGE JA and EVD-LabNet were invited to participate in an assessment of the response of European laboratories to the EBOV outbreak, to identify learning points and training needs to strengthen future outbreak responses. Response aspects assessed included diagnostics, biorisk management and quality ass...
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Reusken CB, Mögling R, Smit PW, Grunow R, Ippolito G, Di Caro A, Koopmans M Tags: Euro Surveill Source Type: research

Rubella infection in pregnancy and congenital rubella in United Kingdom, 2003 to 2016.
Abstract Rubella vaccination has been included in the United Kingdom's (UK) routine childhood schedule for nearly 30 years. The UK achieved World Health Organization (WHO) elimination status in 2016 and acute rubella infections are rare. In the period 2003-16, 31 rubella infections in pregnancy (0.23 per 100,000 pregnancies) were identified through routine surveillance, of which 26 were in women who were born abroad. Five of the 31 rubella infections led to congenital rubella syndrome in the infant and three had confirmed congenital rubella infection without congenital rubella syndrome. An additional seven babies ...
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Bukasa A, Campbell H, Brown K, Bedford H, Ramsay M, Amirthalingam G, Tookey P Tags: Euro Surveill Source Type: research

Case-control study on risk factors for acute hepatitis E in Germany, 2012 to 2014.
The objective of this case-control study was to assess risk factors for autochthonous symptomatic hepatitis E and explore reasons for delays in diagnosis. Methods: Demographic, clinical and exposure data from notified hepatitis E cases and individually matched population controls were collected in semi-standardised telephone interviews. Conditional logistic regression analysis was used to calculate matched odds ratios (mOR) and population attributable fractions (PAF). Results: In total, 270 cases and 1,159 controls were included (mean age 53 years, 61% men in both groups). Associated with disease were: consumption of under...
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Faber M, Askar M, Stark K Tags: Euro Surveill Source Type: research

National outbreak of Shiga toxin-producing Escherichia coli O157:H7 linked to mixed salad leaves, United Kingdom, 2016.
Abstract We investigated a large outbreak of Escherichia coli O157 in the United Kingdom (UK) with 165 cases between 31 May and 29 July 2016. No linked cases were reported in other countries. Cases were predominately female (n = 128) and adult (n = 150), 66 attended hospital and nine had features of haemorrhagic uraemic syndrome. A series of epidemiological studies (case-control, case-case, ingredients-based and venue-based studies) and supply chain investigations implicated mixed salad leaves from Supplier A as the likely outbreak vehicle. Whole genome sequencing (WGS) indicated a link with strains from t...
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Gobin M, Hawker J, Cleary P, Inns T, Gardiner D, Mikhail A, McCormick J, Elson R, Ready D, Dallman T, Roddick I, Hall I, Willis C, Crook P, Godbole G, Tubin-Delic D, Oliver I Tags: Euro Surveill Source Type: research

Preventing sepsis in healthcare - 200 years after the birth of Ignaz Semmelweis.
PMID: 29741152 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Pittet D, Allegranzi B Tags: Euro Surveill Source Type: research

Prolonged detection of dengue virus RNA in the semen of a man returning from Thailand to Italy, January 2018.
This study reports the presence of dengue virus RNA in longitudinally collected semen samples of a previously healthy Caucasian man, returning to Italy from Thailand with primary dengue fever, up to 37 days post-symptom onset, when viraemia and viruria were undetectable. This finding, coupled with the evidence of dengue virus negative-strand RNA, an indirect marker of ongoing viral replication, in the cellular fraction of semen, indicates a need to further investigate possible sexual transmission. PMID: 29741153 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Lalle E, Colavita F, Iannetta M, Gebremeskel Teklè S, Carletti F, Scorzolini L, Bordi L, Vincenti D, Castilletti C, Ippolito G, Capobianchi MR, Nicastri E Tags: Euro Surveill Source Type: research

Novel application of the matched case-control design to compare food supply chains during an Escherichia coli O157 outbreak, United Kingdom, 2016.
Abstract There is a need for innovative methods to investigate outbreaks of food-borne infection linked to produce with a complex distribution network. The investigation of a large outbreak of Escherichia coli O157 PT34 infection in the United Kingdom in 2016 indicated that catering venues associated with multiple cases had used salad leaves sourced from one supplier. Our aim was to investigate whether catering venues linked to cases were more likely to have used salad leaves from this supplier. We conducted a matched case-control study, with catering venues as the units of analysis. We compared venues linked to c...
Source: Euro Surveill - May 1, 2018 Category: Infectious Diseases Authors: Inns T, Cleary P, Bundle N, Foulkes S, Sharp A, Utsi L, McBrien C, Teagle R, Waldram A, Williams C, McCann C, Smith R, Saleh S, McCarthy N, Vivancos R, Hawker J, Decraene V Tags: Euro Surveill Source Type: research

Vaccine hesitancy in the French population in 2016, and its association with vaccine uptake and perceived vaccine risk-benefit balance.
Conclusion: Further research is needed to study the association between VH and vaccine uptake for other vaccines, and to design and validate measurement tools to monitor VH over time. PMID: 29717693 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Rey D, Fressard L, Cortaredona S, Bocquier A, Gautier A, Peretti-Watel P, Verger P, On Behalf Of The Baromètre Santé Group Tags: Euro Surveill Source Type: research

Vaccines, trust and European public health.
te; X PMID: 29717694 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Ammon A, Prats Monné X Tags: Euro Surveill Source Type: research

A modified chain binomial model to analyse the ongoing measles epidemic in Greece, July 2017 to February 2018.
Abstract Greece is currently experiencing a large measles outbreak, in the context of multiple similar outbreaks across Europe. We devised and applied a modified chain-binomial epidemic model, requiring very simple data, to estimate the transmission parameters of this outbreak. Model results indicate sustained measles transmission among the Greek Roma population, necessitating a targeted mass vaccination campaign to halt further spread of the epidemic. Our model may be useful for other countries facing similar measles outbreaks. PMID: 29717695 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Lytras T, Georgakopoulou T, Tsiodras S Tags: Euro Surveill Source Type: research

Extension of French vaccination mandates: from the recommendation of the Steering Committee of the Citizen Consultation on Vaccination to the law.
lon F Abstract On 4 December 2017, French parliamentarians passed a law extending the vaccination mandates for children up to 2 years of age from three vaccinations (against diphtheria, tetanus and poliomyelitis) to 11 by adding vaccinations against pertussis, Haemophilus influenza b (Hib), hepatitis B, pneumococcal diseases, meningococcal C diseases, measles, mumps and rubella. This vote follows a recommendation made by the Steering Committee of the Citizen Consultation on Vaccination that took place in 2016. The law applies to all children born after 1 January 2018. Parents who do not fulfil the mandate will not...
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Lévy-Bruhl D, Desenclos JC, Quelet S, Bourdillon F Tags: Euro Surveill Source Type: research

Adverse events following immunisation with a meningococcal serogroup B vaccine: report from post-marketing surveillance, Germany, 2013 to 2016.
Conclusions: The safety profile described in the Summary of Product Characteristics, in general, is confirmed by data from spontaneous reporting. No safety concerns were identified. PMID: 29717697 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Mentzer D, Oberle D, Keller-Stanislawski B Tags: Euro Surveill Source Type: research

Life in vaccine science - a conversation with Stanley Plotkin at the 4th Conference on Vaccines in Dubrovnik, Croatia, September 2017.
PMID: 29717698 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Musa S Tags: Euro Surveill Source Type: research

Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): results from the Burden of Communicable Diseases in Europe study, European Union and European Economic Area countries, 2009 to 2013.
Conclusions: These results provide baseline estimates for evaluating infectious disease prevention and control strategies. The study promotes an evidence-based approach to describing population health and assessing surveillance data availability and quality, and provides information for the planning and prioritisation of limited resources in infectious disease prevention and control. PMID: 29692315 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Cassini A, Colzani E, Pini A, Mangen MJ, Plass D, McDonald SA, Maringhini G, van Lier A, Haagsma JA, Havelaar AH, Kramarz P, Kretzschmar ME, On Behalf Of The BCoDE Consortium Tags: Euro Surveill Source Type: research

Extended screening for infectious diseases among newly-arrived asylum seekers from Africa and Asia, Verona province, Italy, April 2014 to June 2015.
Conclusions: The screening of viral diseases is questionable because of low prevalence and/or long-term, expensive treatments. For opposing reasons, helminthic infections are probably worth to be targeted by screening strategies in asylum seekers of selected countries of origin. PMID: 29692316 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Buonfrate D, Gobbi F, Marchese V, Postiglione C, Badona Monteiro G, Giorli G, Napoletano G, Bisoffi Z Tags: Euro Surveill Source Type: research

Implementation of MenACWY vaccination because of ongoing increase in serogroup W invasive meningococcal disease, the Netherlands, 2018.
Abstract The annual incidence rate of serogroup W invasive meningococcal disease in the Netherlands increased from 
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Knol MJ, Ruijs WL, Antonise-Kamp L, de Melker HE, van der Ende A Tags: Euro Surveill Source Type: research

Special issue on advanced diagnostics to inform public health policy - deadline extended to 13 May 2018.
PMID: 29692318 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Job vacancy at the European Centre for Disease Prevention and Control.
PMID: 29692319 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Genomic non-coding regions reveal hidden patterns of mumps virus circulation in Spain, 2005 to 2015.
Conclusion: We suggest to consider their use in conjunction with the SH gene in the future WHO recommendations for MuV epidemiological surveillance. PMID: 29667574 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Gavilán AM, Fernández-García A, Rueda A, Castellanos A, Masa-Calles J, López-Perea N, Torres de Mier MV, de Ory F, Echevarría JE Tags: Euro Surveill Source Type: research

A cluster of two human cases of tick-borne encephalitis (TBE) transmitted by unpasteurised goat milk and cheese in Germany, May 2016.
Abstract In May 2016, two cases of tick-borne encephalitis (TBE) were confirmed by serology (positive IgM and IgG antibodies against TBE virus (TBEV) in serum), with a possible link to raw milk and cheese from a goat farm in a region in Baden-Württemberg, Germany not previously known as TBE-endemic. The outbreak investigation identified 32 consumers of goat dairy products (29 consumers, one farm employee, two owners) of whom none had IgM antibodies against TBEV 3-8 weeks after consumption. Of the 27 notified TBE cases in the State, none reported consumption of raw goat milk or cheese from the suspected farm. ...
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Brockmann SO, Oehme R, Buckenmaier T, Beer M, Jeffery-Smith A, Spannenkrebs M, Haag-Milz S, Wagner-Wiening C, Schlegel C, Fritz J, Zange S, Bestehorn M, Lindau A, Hoffmann D, Tiberi S, Mackenstedt U, Dobler G Tags: Euro Surveill Source Type: research

Case of seasonal reassortant A(H1N2) influenza virus infection, the Netherlands, March 2018.
Abstract A seasonal reassortant A(H1N2) influenza virus harbouring genome segments from seasonal influenza viruses A(H1N1)pdm09 (HA and NS) and A(H3N2) (PB2, PB1, PA, NP, NA and M) was identified in March 2018 in a 19-months-old patient with influenza-like illness (ILI) who presented to a general practitioner participating in the routine sentinel surveillance of ILI in the Netherlands. The patient recovered fully. Further epidemiological and virological investigation did not reveal additional cases. PMID: 29667576 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Meijer A, Swaan CM, Voerknecht M, Jusic E, van den Brink S, Wijsman LA, Voordouw BC, Donker GA, Sleven J, Dorigo-Zetsma WW, Svraka S, van Boven M, Haverkate MR, Timen A, van Dissel JT, Koopmans MP, Bestebroer TM, Fouchier RA Tags: Euro Surveill Source Type: research

People living with undiagnosed HIV infection and a low CD4 count: estimates from surveillance data, Italy, 2012 to 2014.
Abstract Background and aimsLate HIV diagnosis is associated with onward HIV transmission, higher morbidity, mortality and healthcare costs. In Italy, more than half of people living with HIV were diagnosed late during the last decade, with a CD4 count 
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Regine V, Dorrucci M, Pezzotti P, Mammone A, Quinten C, Pharris A, Suligoi B, The Regional Representatives Of The National Hiv Surveillance System Tags: Euro Surveill Source Type: research

The effectiveness and cost-effectiveness of screening for active tuberculosis among migrants in the EU/EEA: a systematic review.
Discussion: Screening programmes for active TB are most efficient when targeting migrants from higher TB incidence countries. The limited number of studies identified and the heterogeneous evidence highlight the need for further data to inform screening programmes for migrants in the EU/EEA. PMID: 29637888 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Greenaway C, Pareek M, Abou Chakra CN, Walji M, Makarenko I, Alabdulkarim B, Hogan C, McConnell T, Scarfo B, Christensen R, Tran A, Rowbotham N, Noori T, van der Werf MJ, Pottie K, Matteelli A, Zenner D, Morton RL Tags: Euro Surveill Source Type: research

The effectiveness and cost-effectiveness of screening for latent tuberculosis among migrants in the EU/EEA: a systematic review.
Discussion: The effectiveness of LTBI programmes is limited by the large pool of migrants with LTBI, poorly predictive tests, long treatments and a weak care cascade. Targeted LTBI programmes that ensure high screening uptake and treatment completion will have greatest individual and public health benefit. PMID: 29637889 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: Greenaway C, Pareek M, Abou Chakra CN, Walji M, Makarenko I, Alabdulkarim B, Hogan C, McConnell T, Scarfo B, Christensen R, Tran A, Rowbotham N, van der Werf MJ, Noori T, Pottie K, Matteelli A, Zenner D, Morton RL Tags: Euro Surveill Source Type: research

West Nile virus outbreak in humans and epidemiological surveillance, west Andalusia, Spain, 2016.
e-Gómez S, Ruiz-Fernández J Abstract In Andalusia, Spain, West Nile virus (WNV) surveillance takes place from April to November, during the active vector period. Within this area seroconversion to this virus was evidenced in wild birds in 2004, affecting horses and two humans for the first time in 2010. Since 2010, the virus has been isolated every year in horses, and national and regional surveillance plans have been updated with the epidemiological changes found. WNV is spreading rapidly throughout southern Europe and has caused outbreaks in humans. Here we describe the second WNV outbreak in human...
Source: Euro Surveill - April 1, 2018 Category: Infectious Diseases Authors: López-Ruiz N, Montaño-Remacha MDC, Durán-Pla E, Pérez-Ruiz M, Navarro-Marí JM, Salamanca-Rivera C, Miranda B, Oyonarte-Gómez S, Ruiz-Fernández J Tags: Euro Surveill Source Type: research

Candida auris: epidemiological situation, laboratory capacity and preparedness in European Union and European Economic Area countries, 2013 to 2017.
Abstract During 2013-2017, 620 cases of Candida auris were reported in the European Union/European Economic Area - 466 (75.2%) colonisations, 110 (17.7%) bloodstream infections, 40 (6.5%) other infections and four cases (0.6%) of unknown colonisation/infection status - the majority from four large outbreaks. Survey results showed that several countries lacked laboratory capacity and/or information on the occurrence of cases at national level. To prevent further spread, adequate laboratory capacity and infection control preparedness is required in Europe. PMID: 29616608 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Kohlenberg A, Struelens MJ, Monnet DL, Plachouras D, The Candida Auris Survey Collaborative Group Tags: Euro Surveill Source Type: research

Job vacancy at the European Centre for Disease Prevention and Control.
PMID: 29616609 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

A case of respiratory toxigenic diphtheria: contact tracing results and considerations following a 30-year disease-free interval, Catalonia, Spain, 2015.
ona S, Pumarola T Abstract In May 2015, following a 30-year diphtheria-free interval in Catalonia, an unvaccinated 6-year-old child was diagnosed with diphtheria caused by toxigenic Corynebacterium diphtheriae. After a difficult search for equine-derived diphtheria antitoxin (DAT), the child received the DAT 4 days later but died at the end of June. Two hundred and seventeen contacts were identified in relation to the index case, and their vaccination statuses were analysed, updated and completed. Of these, 140 contacts underwent physical examination and throat swabs were taken from them for analysis. Results were...
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Jané M, Vidal MJ, Camps N, Campins M, Martínez A, Balcells J, Martin-Gomez MT, Bassets G, Herrera-León S, Foguet A, Maresma M, Follia N, Uriona S, Pumarola T Tags: Euro Surveill Source Type: research

Dominant influenza A(H3N2) and B/Yamagata virus circulation in EU/EEA, 2016/17 and 2017/18 seasons, respectively.
Abstract We use surveillance data to describe influenza A and B virus circulation over two consecutive seasons with excess all-cause mortality in Europe, especially in people aged 60 years and older. Influenza A(H3N2) virus dominated in 2016/17 and B/Yamagata in 2017/18. The latter season was prolonged with positivity rates above 50% among sentinel detections for at least 12 weeks. With a current west-east geographical spread, high influenza activity might still be expected in eastern Europe. PMID: 29616611 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Adlhoch C, Snacken R, Melidou A, Ionescu S, Penttinen P, The European Influenza Surveillance Network Tags: Euro Surveill Source Type: research

In the national epidemiological bulletins - a selection from recent issues.
PMID: 29616613 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Rise and fall of outbreak-specific clone inside endemic pulsotype of Salmonella 4,[5],12:i:-; insights from high-resolution molecular surveillance in Emilia-Romagna, Italy, 2012 to 2015.
Conclusions: The study provided evidence for the remarkable prevention potential of whole genome sequencing used as a routine tool in systems that integrate human, food and animal surveillance. PMID: 29616614 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Morganti M, Bolzoni L, Scaltriti E, Casadei G, Carra E, Rossi L, Gherardi P, Faccini F, Arrigoni N, Sacchi AR, Delledonne M, Pongolini S Tags: Euro Surveill Source Type: research

Note from the editors: World Tuberculosis Day 2018 and Special issue-Screening and prevention of infectious diseases in newly arrived migrants in Europe.
PMID: 29589576 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Hepatitis E virus (HEV) in Scotland: evidence of recent increase in viral circulation in humans.
Abstract BackgroundPrevious studies showed low levels of circulating hepatitis E virus (HEV) in Scotland. We aimed to reassess current Scottish HEV epidemiology. Methods: Blood donor samples from five Scottish blood centres, the minipools for routine HEV screening and liver transplant recipients were tested for HEV antibodies and RNA to determine seroprevalence and viraemia. Blood donor data were compared with results from previous studies covering 2004-08. Notified laboratory-confirmed hepatitis E cases (2009-16) were extracted from national surveillance data. Viraemic samples from blood donors (2016) and chronic...
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Thom K, Gilhooly P, McGowan K, Malloy K, Jarvis LM, Crossan C, Scobie L, Blatchford O, Smith-Palmer A, Donnelly MC, Davidson JS, Johannessen I, Simpson KJ, Dalton HR, Petrik J Tags: Euro Surveill Source Type: research

Universal screening for latent and active tuberculosis (TB) in asylum seeking children, Bochum and Hamburg, Germany, September 2015 to November 2016.
Conclusions: Asylum seeking children from high and low incidence countries are both at risk of developing LTBI or active TB. Universal TB screening for all asylum seeking children should be considered. PMID: 29589578 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Mueller-Hermelink M, Kobbe R, Methling B, Rau C, Schulze-Sturm U, Auer I, Ahrens F, Brinkmann F Tags: Euro Surveill Source Type: research

Field investigation with real-time virus genetic characterisation support of a cluster of Ebola virus disease cases in Dubr éka, Guinea, April to June 2015.
We describe the epidemiological and molecular investigations of this event. We used the Dubréka EVD registers and the Ebola treatment centre's (ETC) records to characterise chains of transmission. Real-time field Ebola virus sequencing was employed to support epidemiological results. An epidemiological cluster of 32 cases was found, of which 27 were laboratory confirmed, 24 were isolated and 20 died. Real-time viral sequencing on 12 cases demonstrated SL3 lineage viruses with sequences differing by one to three nt inside a single phylogenetic cluster. For isolated cases, the average time between symptom onset and ET...
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Pini A, Zomahoun D, Duraffour S, Derrough T, Charles M, Quick J, Loman N, Cowley L, Leno M, Ouedraogo N, Thiam O, Hernández-Romieu A, Iko A, Keita H, Konate D, Soumah AA, Bouchouar E, Ileka-Priouzeau S, Keita S, Diallo B, Cisse F, Jansa J, Carroll M, Gü Tags: Euro Surveill Source Type: research

Increased risk of yellow fever infections among unvaccinated European travellers due to ongoing outbreak in Brazil, July 2017 to March 2018.
Abstract Since December 2016, Brazil has faced a large outbreak of yellow fever with ca 1,500 confirmed human cases. In the first 2 months of 2018, Brazil reported almost as many cases as in 2017 as a whole. In these 2 months, five imported cases were reported among unvaccinated European travellers. Three had travelled to Ilha Grande, a popular destination among European tourists. Physicians and European travellers visiting Brazil should follow yellow fever vaccination recommendations. PMID: 29560853 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Gossner CM, Haussig JM, de Bellegarde de Saint Lary C, Kaasik Aaslav K, Schlagenhauf P, Sudre B Tags: Euro Surveill Source Type: research

Moving epidemic method (MEM) applied to virology data as a novel real time tool to predict peak in seasonal influenza healthcare utilisation. The Scottish experience of the 2017/18 season to date.
We report the application of the moving epidemic method (MEM) to virology data as a tool to predict the influenza peak activity period and peak week of swab positivity in the current season. This novel MEM application has been successful locally and is believed to be of potential use to other countries for healthcare planning and building wider community resilience. PMID: 29560854 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - March 1, 2018 Category: Infectious Diseases Authors: Murray JLK, Marques DFP, Cameron RL, Potts A, Bishop J, von Wissmann B, William N, Reynolds AJ, Robertson C, McMenamin J Tags: Euro Surveill Source Type: research