Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017.
y Group Abstract Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms. In 2016-17, we performed the second point-prevalence survey (PPS) of healthcare-associated infections (HAIs) and antimicrobial use in European acute care hospitals. We included 1,209 hospitals and 310,755 patients in 28 of 31 European Union/European Economic Area (EU/EEA) countries. The weighted prevalence of antimicrobial use in the EU/EEA was 30.5% (95% CI: 29.2-31.9%). The most common indication for prescribing antimicrobials was...
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Plachouras D, Kärki T, Hansen S, Hopkins S, Lyytikäinen O, Moro ML, Reilly J, Zarb P, Zingg W, Kinross P, Weist K, Monnet DL, Suetens C, The Point Prevalence Survey Study Group Tags: Euro Surveill Source Type: research

Antimicrobials in acute and long-term care: a point in time along the way to improved use.
PMID: 30458918 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Neuhauser MM, Weber JT Tags: Euro Surveill Source Type: research

Congenital brain abnormalities during a Zika virus epidemic in Salvador, Brazil, April 2015 to July 2016.
ConclusionThis study highlights the magnitude of neurological consequences of the ZIKV epidemic and the limitations of head circumference in accurately identifying children with CBA. Gestational symptoms compatible with ZIKV infection should be combined with imaging studies for efficient detection of suspect CBAs during ZIKV epidemics. PMID: 30424827 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Kikuti M, Cardoso CW, Prates APB, Paploski IAD, Kitron U, Reis MG, Mochida GH, Ribeiro GS Tags: Euro Surveill Source Type: research

High rates of meticillin-resistant Staphylococcus aureus among asylum seekers and refugees admitted to Helsinki University Hospital, 2010 to 2017.
Abstract IntroductionAntimicrobial resistance is increasing rapidly in countries with low hygiene levels and poorly controlled antimicrobial use. The spread of resistant bacteria poses a threat to healthcare worldwide. Refugees and migrants from high-prevalence countries may add to a rise in multidrug-resistant (MDR) bacteria in low-prevalence countries. However, respective data are scarce.MethodsWe retrospectively collected microbiological and clinical data from asylum seekers and refugees treated at Helsinki University Hospital between January 2010 and August 2017.ResultsOf 447 asylum seekers and refugees (Iraq:...
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Aro T, Kantele A Tags: Euro Surveill Source Type: research

Tick-borne encephalitis in Europe, 2012 to 2016.
ler H Abstract Since 2012, tick-borne encephalitis (TBE) is a notifiable in the European Union. The European Centre for Disease Prevention and Control annually collects data from 28 countries plus Iceland and Norway, based on the EU case definition. Between 2012 and 2016, 23 countries reported 12,500 TBE cases (Ireland and Spain reported none), of which 11,623 (93.0%) were confirmed cases and 878 (7.0%) probable cases. Two countries (Czech Republic and Lithuania) accounted for 38.6% of all reported cases, although their combined population represented only 2.7% of the population under surveillance. The annual noti...
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Beauté J, Spiteri G, Warns-Petit E, Zeller H Tags: Euro Surveill Source Type: research

Echovirus type 6 transmission clusters and the role of environmental surveillance in early warning, the Netherlands, 2007 to 2016.
ConclusionAlgorithms using combined time-place-phylogeny data allowed identification of clusters not detected by any of these variables alone. EEVS identified strains circulating in the population, but EEVS samples did not systematically precede clinical case surveillance, limiting EEVS usefulness for early warning in a context where E6 is endemic. PMID: 30424830 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Monge S, Benschop K, Soetens L, Pijnacker R, Hahné S, Wallinga J, Duizer E Tags: Euro Surveill Source Type: research

High prevalence of carriage of mcr-1-positive enteric bacteria among healthy children from rural communities in the Chaco region, Bolivia, September to October 2016.
ConclusionThis high prevalence of mcr-1-like carriage, in absence of professional exposure, is unexpected. Its extent at the national level should be investigated with priority. Possible causes should be studied; they may include unrestricted use of colistin in veterinary medicine and animal breeding, and importation of mcr-1-positive bacteria via food and animals. PMID: 30424831 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Giani T, Sennati S, Antonelli A, Di Pilato V, di Maggio T, Mantella A, Niccolai C, Spinicci M, Monasterio J, Castellanos P, Martinez M, Contreras F, Balderrama Villaroel D, Damiani E, Maury S, Rocabado R, Pallecchi L, Bartoloni A, Rossolini GM Tags: Euro Surveill Source Type: research

Creating a web-based electronic tool to aid tuberculosis (TB) cluster investigation: data integration in TB surveillance activities in the United Kingdom, 2013 to 2016.
Abstract Molecular technology to identify relatedness between Mycobacterium tuberculosis complex isolates, representative of possible tuberculosis (TB) transmission between individuals, continues to evolve. At the same time, tools to utilise this information for public health action to improve TB control should also be implemented. Public Health England developed the Strain Typing Module (STM) as an integral part of the web-based surveillance system used in the United Kingdom following the roll-out of prospective 24 loci mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) strain ty...
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Davidson JA, Anderson LF, Adebisi V, de Jongh L, Burkitt A, Lalor MK Tags: Euro Surveill Source Type: research

Characterisation of HIV-1 transmission clusters and drug-resistant mutations in Denmark, 2004 to 2016.
This study describes the prevalence of human immunodeficiency virus (HIV) drug resistance mutations among 1,815 patients in Denmark from 2004 to 2016 and characterises transmission clusters. POL sequences were analysed for subtype, drug resistance mutations and phylogenetic relationship. The prevalence of surveillance drug resistance mutations (SDRM) was 6.7%, while the prevalence of drug resistance mutations (DRM) with a clinical impact was 12.3%. We identified 197 transmission clusters with 706 patients. Patients 40 years or older were less likely to be members of a transmission cluster and patients in transmission clust...
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Petersen A, Cowan SA, Nielsen J, Fischer TK, Fonager J Tags: Euro Surveill Source Type: research

Addendum for Euro Surveill. 2018;23(10).
PMID: 30401011 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

An unusual outbreak of norovirus associated with a Halloween-themed swimming pool party in England, 2016.
Abstract In October 2016, an outbreak of norovirus occurred among attendees of a Halloween-themed party at a public swimming pool in the south-east of England. Norovirus genogroup II was confirmed in 11 cases. In the retrospective cohort study of pool users, 68 individuals (37 female and 31 male), with a median age of 11 years (range: 0-50 years), met the case definition of developing diarrhoea or vomiting between 6 and 72 h after the pool visit. Multivariable analysis showed that increasing age was associated with a reduced risk of illness (odds ratio = 0.91; 95% confidence interval: 0.83-0.99). Pool behaviou...
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Paranthaman K, Pringle E, Burgess A, Macdonald N, Sedgwick J Tags: Euro Surveill Source Type: research

Upsurge in echovirus 30 detections in five EU/EEA countries, April to September, 2018.
Abstract An upsurge in Echovirus 30 (E30) infections, associated with meningitis/meningoencephalitis, has been observed in Denmark, Germany, the Netherlands, Norway and Sweden in the period April to September 2018, compared with 2015-2017. In total, 658 E30 infections among 4,537 enterovirus infections were detected in 15 countries between January and September 2018 and affected mainly newborns and 26-45 year-olds. National public health institutes are reminded to remain vigilant and inform clinicians of the ongoing epidemic. PMID: 30401013 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2018 Category: Infectious Diseases Authors: Broberg EK, Simone B, Jansa J, The Eu/Eea Member State Contributors Tags: Euro Surveill Source Type: research

Lymphogranuloma venereum (LGV) in men who have sex with men (MSM): a re-emerging problem, Malta, 2018.
Abstract From 1 January to 30 June 2018, 11 cases of Lymphogranuloma venereum (LGV; all preserved samples (n = 4) genovar L2b) were identified at the Genitourinary Clinic (GUC), Mater Dei Hospital, Msida, Malta. All cases were diagnosed in men who have sex with men (MSM); six participated in three group-sex parties. Here, we describe the outbreak and risk factors associated with LGV diagnoses in MSM in Malta in 2018. PMID: 30376912 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Donachie A, Spiteri G, Barbara C, Melillo T, Hadad R, Gauci Farrugia A, Unemo M, Padovese V Tags: Euro Surveill Source Type: research

Increase in human West Nile and Usutu virus infections, Austria, 2018.
Abstract Between 28 June and 17 September 2018, 27 cases of human West Nile virus infections were recorded in Austria; four cases of West Nile neuroinvasive disease, 11 cases of West Nile fever, six infections detected by blood donation screening and six imported cases. In addition, 18 cases of human Usutu virus infections (all blood donors) were recorded. This is the highest number of annual infections recorded in Austria since the introduction of both viruses. PMID: 30376913 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Aberle SW, Kolodziejek J, Jungbauer C, Stiasny K, Aberle JH, Zoufaly A, Hourfar MK, Weidner L, Nowotny N Tags: Euro Surveill Source Type: research

Job vacancies at the European Centre for Disease Prevention and Control.
PMID: 30376914 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Influenza vaccine effectiveness in reducing severe outcomes over six influenza seasons, a case-case analysis, Spain, 2010/11 to 2015/16.
ized Cases In Catalonia Abstract PMID: 30376915 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Godoy P, Romero A, Soldevila N, Torner N, Jané M, Martínez A, Caylà JA, Rius C, Domínguez A, The Working Group On Surveillance Of Severe Influenza Hospitalized Cases In Catalonia Tags: Euro Surveill Source Type: research

Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018.
rtner B Abstract Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical products during manufacturing may lead to international outbreaks. PMID: 30352639 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Becker SL, Berger FK, Feldner SK, Karliova I, Haber M, Mellmann A, Schäfers HJ, Gärtner B Tags: Euro Surveill Source Type: research

Antimicrobial resistance of major clinical pathogens in South Korea, May 2016 to April 2017: first one-year report from Kor-GLASS.
We describe results from the first year of operation of the Kor-GLASS from May 2016 to April 2017, comprising all non-duplicated clinical isolates of major pathogens from blood, urine, faeces and urethral and cervical swabs from six sentinel hospitals. Antimicrobial susceptibility tests were carried out by disk diffusion, Etest, broth microdilution and agar dilution methods. Among 67,803 blood cultures, 3,523 target pathogens were recovered. The predominant bacterial species were Escherichia coli (n = 1,536), Klebsiella pneumoniae (n = 597) and Staphylococcus aureus (n = 584). From 57,477 urine cultures, 6,394 E. coli and ...
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Lee H, Yoon EJ, Kim D, Jeong SH, Won EJ, Shin JH, Kim SH, Shin JH, Shin KS, Kim YA, Uh Y, Yang JW, Kim IH, Park C, Lee KJ Tags: Euro Surveill Source Type: research

Antimicrobial resistance surveillance in Europe and beyond.
PMID: 30352641 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Simonsen GS Tags: Euro Surveill Source Type: research

Authors' correction for Euro Surveill. 2018;23(39).
PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Authors' correction for Euro Surveill. 2018;23(39). Tags: Euro Surveill Source Type: research

Establishment of the South Korean national antimicrobial resistance surveillance system, Kor-GLASS, in 2016.
In this report, we summarise principles and processes in order to share our experiences with other countries planning to establish a national AMR surveillance system. The pilot operation of Kor-GLASS allowed us to understand the national burden of specific infectious diseases and the status of bacterial AMR. Issues pertaining to high costs and labour-intensive operation were raised during the pilot, and improvements are being made. PMID: 30352643 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Lee H, Yoon EJ, Kim D, Jeong SH, Shin JH, Shin JH, Shin KS, Kim YA, Uh Y, Park C, Lee KJ Tags: Euro Surveill Source Type: research

Hepatitis E in Italy: 5 years of national epidemiological, virological and environmental surveillance, 2012 to 2016.
Group Abstract Increasing numbers of hepatitis E cases are being reported in several European countries, including Italy, but the burden of hepatitis E virus (HEV) infection is largely unknown in the latter. To gain a better understanding of HEV epidemiology at national level in Italy, we piloted a strengthened and integrated human (epidemiological and virological) and environmental HEV surveillance system between 2012 and 2016. Over the 5-year period, 169 confirmed hepatitis E cases were identified, with a national annual incidence of 0.72 cases per 1,000,000. Of 65 HEV-RNA positive samples of sufficient quality ...
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Alfonsi V, Romanò L, Ciccaglione AR, La Rosa G, Bruni R, Zanetti A, Della Libera S, Iaconelli M, Bagnarelli P, Capobianchi MR, Garbuglia AR, Riccardo F, Tosti ME, Collaborating Group Tags: Euro Surveill Source Type: research

Job vacancy at the European Centre for Disease Prevention and Control.
PMID: 30326992 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Cryptic severe Plasmodium falciparum malaria in a Moroccan man living in Tuscany, Italy, August 2018.
Abstract In August 2018 a Moroccan man living in Tuscany developed Plasmodium falciparum malaria. The patient declared having not recently visited any endemic country, leading to diagnostic delay and severe malaria. As susceptibility to P. falciparum of Anopheles species in Tuscany is very low, and other risk factors for acquiring malaria could not be completely excluded, the case remains cryptic, similar to other P. falciparum malaria cases previously reported in African individuals living in Apulia in 2017. PMID: 30326993 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Zammarchi L, Di Lauria N, Bartalesi F, Suardi LR, Corti G, Mencarini J, Boccolini D, Severini C, Gradoni L, Buonamici C, Garofalo G, Bartolesi AM, Ciccone N, Berni A, Poggesi L, Niccolini F, Rossolini GM, Romi R, Bartoloni A Tags: Euro Surveill Source Type: research

Hepatitis A outbreak linked to imported frozen strawberries by sequencing, Sweden and Austria, June to September 2018.
erth JL Abstract Between June-September 2018, 20 hepatitis A cases were notified in six counties in Sweden. Combined epidemiological and microbiological investigations identified imported frozen strawberries produced in Poland as the source of the outbreak. Sequence analysis confirmed the outbreak strain IB in the strawberries with 100 % identity and the respective batch was withdrawn. Sharing the sequence information internationally led to the identification of 14 additional cases in Austria, linked to strawberries from the same producer. PMID: 30326994 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Enkirch T, Eriksson R, Persson S, Schmid D, Aberle SW, Löf E, Wittesjö B, Holmgren B, Johnzon C, Gustafsson EX, Svensson LM, Sandelin LL, Richter L, Lindblad M, Brytting M, Maritschnik S, Tallo T, Malm T, Sundqvist L, Ederth JL Tags: Euro Surveill Source Type: research

The impact of 10 years of human papillomavirus (HPV) vaccination in Australia: what additional disease burden will a nonavalent vaccine prevent?
CONCLUSIONS: Vaccination using 4vHPV vaccine has had a large demonstrable impact on HPV-related disease in Australia. A switch to 9vHPV could further reduce the HPV-associated cancer burden. With continued high coverage among both males and females, elimination of vaccine-type HPV disease seems achievable in Australia. PMID: 30326995 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Patel C, Brotherton JM, Pillsbury A, Jayasinghe S, Donovan B, Macartney K, Marshall H Tags: Euro Surveill Source Type: research

Divergent approaches in the vaccination of recently arrived migrants to Europe: a survey of national experts from 32 countries, 2017.
Conclusion: Existing guidance is often not migrant-specific and may not be applied in practice; clarification is needed on which vaccines should be given. Strategies are needed specifically for catch-up vaccination in adult migrants. Vaccinations should be offered in multiple settings, free of charge, with sufficient guidance and training provided to front-line healthcare professionals. PMID: 30326996 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Hargreaves S, Nellums LB, Ravensbergen SJ, Friedland JS, Stienstra Y, On Behalf Of The Esgitm Working Group On Vaccination In Migrants Tags: Euro Surveill Source Type: research

Surveillance on speed: Being aware of infectious diseases in migrants mass accommodations - an easy and flexible toolkit for field application of syndromic surveillance, Germany, 2016 to 2017.
Abstract Europe received an increased number of migrants in 2015. Housing in inadequate mass accommodations (MA) made migrants prone to infectious disease outbreaks. In order to enhance awareness for infectious diseases (ID) and to detect clusters early, we developed and evaluated a syndromic surveillance system in three MA with medical centres in Berlin, Germany. Healthcare workers transferred daily data on 14 syndromes to the German public health institute (Robert Koch-Institute). Clusters of ID syndromes and single cases of outbreak-prone diseases produced a signal according to a simple aberration-detection alg...
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Sarma N, Ullrich A, Wilking H, Ghozzi S, Lindner AK, Weber C, Holzer A, Jansen A, Stark K, Vygen-Bonnet S Tags: Euro Surveill Source Type: research

Summary of available surveillance data on hepatitis C virus infection from eight Arctic countries, 2012 to 2014.
Abstract We summarised available hepatitis C virus (HCV) surveillance data for 2012-14 from Arctic/sub-Arctic countries/regions. We sent a HCV data collection template by email to public health authorities in all jurisdictions. Population statistics obtained from census sources for each country were used to estimate rates of reported acute and chronic/undifferentiated HCV cases. Seven countries with Arctic regions (Canada, Denmark, Finland, Greenland, Norway, Sweden and the United States, represented by the state of Alaska), including three Canadian territories and one province, as well as 11 Russian subnational A...
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Gounder PP, Koch A, Provo G, Lovlie A, Ederth JL, Axelsson M, Archibald CP, Hanley B, Mullen A, Matheson M, Allison D, Trykker H, Hennessy TW, Kuusi M, Chulanov V, McMahon BJ Tags: Euro Surveill Source Type: research

Addendum for Euro Surveill. 2018;23(15).
PMID: 30301490 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Authors' correction for Euro Surveill. 2018;23(28).
PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Authors' correction for Euro Surveill. 2018;23(28). Tags: Euro Surveill Source Type: research

Screening for neurocysticercosis in internationally adopted children: yield, cost and performance of serological tests, Italy, 2001 to 2016.
Conclusion: On the base of our findings we suggest the ongoing serological screening for cysticercosis to be discontinued, at least in Italy, until further evidence in support will be available. PMID: 30301492 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2018 Category: Infectious Diseases Authors: Zammarchi L, Angheben A, Fantoni T, Chiappini E, Mantella A, Galli L, Marchese V, Zavarise G, Bisoffi Z, Bartoloni A Tags: Euro Surveill Source Type: research

In the national epidemiological bulletins - a selection from recent issues.
PMID: 30280686 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

The shift in rabies epidemiology in France: time to adjust rabies post-exposure risk assessment.
Abstract The epidemiology of rabies in France and western Europe has changed during the past 22 years. In France, rabies in non-flying terrestrial mammals was declared to be eliminated in 2001, and the risk of rabies is now limited to contact with bats, rabid animals illegally imported from rabies-enzootic countries and traveller exposure in enzootic areas. We analysed the epidemiology of rabies in France from 1995 to 2016, describing and analysing data on human rabies surveillance as well as data on post-exposure prophylaxis (PEP) collected from the network of French antirabies clinics. Over the study period, sev...
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Parize P, Dacheux L, Larrous F, Bourhy H, The French Network Of Antirabies Clinics Tags: Euro Surveill Source Type: research

Uptake and effectiveness of influenza vaccine in those aged 65 years and older in the United Kingdom, influenza seasons 2010/11 to 2016/17.
Conclusions: Vaccine uptake with non-adjuvanted, normal-dose vaccines remained high, with evidence of effectiveness against influenza A(H1N1)pdm09 and B, though poor against A(H3N2), particularly in those aged 75 years and older. Forthcoming availability of newly licensed vaccines with wider use of antivirals can potentially further improve prevention and control of influenza in this group. PMID: 30280688 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Pebody RG, Warburton F, Andrews N, Sinnathamby M, Yonova I, Reynolds A, Robertson C, Cottrell S, Sartaj M, Gunson R, Donati M, Moore C, Ellis J, de Lusignan S, McMenamin J, Zambon M Tags: Euro Surveill Source Type: research

Transmission of toxigenic Corynebacterium diphtheriae by a fully immunised resident returning from a visit to West Africa, United Kingdom, 2017.
Abstract In early 2017, a United Kingdom (UK)-born person in their 20s presented with a skin ulcer on the foot 3 weeks after returning from Ghana. The patient had last received a diphtheria-containing vaccine in 2013, completing the recommended course. MALDI-TOF of a cutaneous swab identified Corynebacterium diphtheriae. Real-time PCR ascertained the species and presence of the diphtheria toxin gene. An Elek test confirmed toxigenicity. The isolate was macrolide sensitive and penicillin resistant. The local Public Health England (PHE) Health Protection Team obtained the patient's clinical history and traced contac...
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Edwards D, Kent D, Lester C, Brown CS, Murphy ME, Brown NM, Sule O, Itani A, Chand M, Trindall A, Pearson C, Roddick I, Fry NK, Hoffmann J, Iyanger N, Kemp L, White J, Javid B, Ramsay ID, Zenner D, Ahmed A, Amirthalingam G, Salimee S, Litt D, Reacher M Tags: Euro Surveill Source Type: research

Large outbreak of mumps virus genotype G among vaccinated students in Norway, 2015 to 2016.
gvik E, Riise ØR Abstract From 6 September 2015-May 2016, a large mumps outbreak occurred among vaccinated students in Norway. A case was defined as a person presenting with a clinical mumps infection, notified between 1 September 2015 and 30 June 2016. Confirmed cases had positive laboratory confirmation and probable cases had an epidemiological link; PCR-positive specimens were genotyped. A total of 232 cases were notified (230 confirmed) with median age of 23 years (range 4-81) and 61% were male. Of 68 (30%) confirmed cases that were genotyped, 66 were genotype G and associated with the outbreak. Cases t...
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Veneti L, Borgen K, Borge KS, Danis K, Greve-Isdahl M, Konsmo K, Njølstad G, Nordbø SA, Øystese KS, Rykkvin R, Sagvik E, Riise ØR Tags: Euro Surveill Source Type: research

Outbreak of human leptospirosis linked to contaminated water bodies in Northern Israel, June to August 2018.
We report preliminary findings of a large outbreak of human leptospirosis with 36 confirmed/probable and 583 suspected cases from June-August 2018, linked to contaminated water bodies in Northern Israel. There was a travel-associated case in Germany; additional cases are being investigated in other countries. The presumed chain of transmission, implicating wild boar and cattle, raises multiple challenges for risk assessment, risk management and risk communication currently being addressed by a public health response team. PMID: 30255835 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Dadon Y, Haas EJ, Kaliner E, Anis E, Singer SR, Atiya-Nasagi Y, Cohen-Dar M, Avramovich E, King R, Sued O, Goshen T, Amit S, Miskin I, Gino E, Yishai R, Sheffer R, Grotto I, Moran-Gilad J Tags: Euro Surveill Source Type: research

Two cases of monkeypox imported to the United Kingdom, September 2018.
We describe the epidemiology and the public health response for the first diagnosed cases outside the African continent since 2003. PMID: 30255836 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Vaughan A, Aarons E, Astbury J, Balasegaram S, Beadsworth M, Beck CR, Chand M, O'Connor C, Dunning J, Ghebrehewet S, Harper N, Howlett-Shipley R, Ihekweazu C, Jacobs M, Kaindama L, Katwa P, Khoo S, Lamb L, Mawdsley S, Morgan D, Palmer R, Phin N, Russell K Tags: Euro Surveill Source Type: research

Job vacancy at the European Centre for Disease Prevention and Control.
PMID: 30229721 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Letter to the editor: Occurrence of modified measles during outbreak in Taiwan in 2018.
PMID: 30229722 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Chen CJ, Lin TY, Huang YC Tags: Euro Surveill Source Type: research

Usability of the international HAVNet hepatitis A virus database for geographical annotation, backtracing and outbreak detection.
Conclusion: Analysis of a subset of short, shared sequences indicates that a geographical annotation on the level of individual countries is possible with the HAVNet data. If the current incompleteness and heterogeneity of the data can be improved on, HAVNet could become very useful as a worldwide reference set for geographical annotation and for backtracing and outbreak detection. PMID: 30229723 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Kroneman A, de Sousa R, Verhoef L, Koopmans MPG, Vennema H, On Behalf Of The HAVNet Network Tags: Euro Surveill Source Type: research

Molecular diversity and biennial circulation of enterovirus D68: a systematic screening study in Lyon, France, 2010 to 2016.
Abstract BackgroundUnderstanding enterovirus D68 (EV-D68) circulation patterns as well as risk factors for severe respiratory and neurological illness is important for developing preventive strategies. Methods: Between 2010 and 2016, 11,132 respiratory specimens from hospitalised patients in Lyon, France, were screened for EV-D68 by PCR. Phylogenetic relationships of the viral-protein-1 sequences were reconstructed using maximum-likelihood and Bayesian-Markov-Chain-Monte-Carlo approaches. Results: Overall, 171 infections with a biennial pattern were detected, including seven, one, 55, none, 42, one and 65 cases an...
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Kramer R, Sabatier M, Wirth T, Pichon M, Lina B, Schuffenecker I, Josset L Tags: Euro Surveill Source Type: research

National outbreak of Pseudomonas aeruginosa associated with an aftercare solution following piercings, July to September 2016, England.
We report a national Pseudomonas aeruginosa outbreak from a common source following piercings between July and September 2016 in England. The multi-agency outbreak investigation included active case finding, microbiological testing of environmental samples and case specimens including Variable Number Tandem Repeat (VNTR) typing and a retrospective cohort study. Overall, 162 outbreak cases (29 confirmed, 14 probable and 119 possible) and 14 non-outbreak cases were identified; all confirmed cases had ear piercings (93% cartilage). Outbreak cases were predominantly female (95%) and had a median age of 18 years (interquartile ...
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Evans H, Bolt H, Heinsbroek E, Lloyd B, English P, Latif S, Elviss N, Turton J, Hoffman P, Crook P, Puleston R, On Behalf Of The Outbreak Control Team Tags: Euro Surveill Source Type: research

ESCAIDE 2018 - call for late breakers.
PMID: 30205869 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Trends and determinants of antimicrobial susceptibility of Neisseria gonorrhoeae in the Netherlands, 2007 to 2015.
BH Abstract BackgroundNeisseria gonorrhoeae antibiotic resistance surveillance is important to maintain adequate treatment. We analysed 2007-15 data from the Gonococcal Resistance to Antimicrobials Surveillance (GRAS), which currently includes 19 of 25 sexually transmitted infection (STI) centres in the Netherlands. Methods: From each patient with a gonorrhoea culture, the minimum inhibitory concentration (MIC) for several antibiotics was determined. Time trends were assessed by geometric means and linear regression of logarithmic MIC. Determinants for decreased susceptibility to ceftriaxone (MIC >&thin...
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Hofstraat SH, Götz HM, van Dam AP, van der Sande MA, van Benthem BH Tags: Euro Surveill Source Type: research

Yellow fever cases in French Guiana, evidence of an active circulation in the Guiana Shield, 2017 and 2018.
Abstract French Guiana (FG) is a French overseas region bordering Brazil and Suriname that is considered endemic for yellow fever (YF); vaccination is compulsory for residents and travellers. In August 2017 and 2018, two sporadic YF cases were notified 1 year apart, confirming that sylvatic YF virus circulation is active in the region. YF vaccination coverage should be closely monitored and improved in FG and neighbouring territories and clinicians should be aware of the risk. PMID: 30205871 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Sanna A, Andrieu A, Carvalho L, Mayence C, Tabard P, Hachouf M, Cazaux CM, Enfissi A, Rousset D, Kallel H Tags: Euro Surveill Source Type: research

Call for ECDC Fellowship Programme cohort 2019.
PMID: 30205872 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 1, 2018 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Outbreak of multiple strains of non-O157 Shiga toxin-producing and enteropathogenic Escherichia coli associated with rocket salad, Finland, autumn 2016.
Abstract In August 2016, an outbreak of Shiga toxin-producing Escherichia coli (STEC) and enteropathogenic E. coli (EPEC) with 237 cases occurred in the Helsinki metropolitan area, Finland. Gastroenteritis cases were reported at 11 events served by one catering company. Microbiological and epidemiological investigations suggested rocket salad as the cause of the outbreak. STEC ONT: H11 and EPEC O111:H8 strains isolated from food samples containing rocket were identical to the patient isolates. In this outbreak, the reported symptoms were milder than considered before for STEC infection, and the guidelines for...
Source: Euro Surveill - August 1, 2018 Category: Infectious Diseases Authors: Kinnula S, Hemminki K, Kotilainen H, Ruotsalainen E, Tarkka E, Salmenlinna S, Hallanvuo S, Leinonen E, Jukka O, Rimhanen-Finne R Tags: Euro Surveill Source Type: research

Current hepatitis E virus seroprevalence in Swiss blood donors and apparent decline from 1997 to 2016.
Conclusions: HEV seroprevalence in Switzerland is high, but has declined over the last decades. The result shows that primarily endemic HEV infections occur and that current blood products may pose a risk to vulnerable transfusion recipients. Nucleic acid screening of all blood products for HEV will begin in November 2018. PMID: 30180927 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - August 1, 2018 Category: Infectious Diseases Authors: Niederhauser C, Widmer N, Hotz M, Tinguely C, Fontana S, Allemann G, Borri M, Infanti L, Sarraj A, Sigle J, Stalder M, Thierbach J, Waldvogel S, Wiengand T, Züger M, Gowland P Tags: Euro Surveill Source Type: research