Using data from a behavioural survey of men who have sex with men (MSM) to estimate the number likely to present for HIV pre-exposure prophylaxis (PrEP) in Ireland, 2017.
Abstract In Ireland, men who have sex with men (MSM) have increased HIV risk. Pre-exposure prophylaxis (PrEP), combined with safe sex practices, can reduce HIV acquisition. We estimated MSM numbers likely to present for PrEP by applying French PrEP criteria to Irish MSM behavioural survey data. We adjusted for survey bias, calculated proportions accessing testing services and those likely to take PrEP. We estimated 1-3% of MSM in Ireland were likely to present for PrEP. PMID: 29208157 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Nic Lochlainn L, O'Donnell K, Hurley C, Lyons F, Igoe D Tags: Euro Surveill Source Type: research

HIV testing in Europe: Evaluating the impact, added value, relevance and usability of the European Centre for Disease Prevention and Control (ECDC)'s 2010 HIV testing guidance.
CONCLUSION: The guidance has been widely used to develop policies, guidelines, programmes and strategies in the EU/EEA and should be regularly updated due to continuous developments in the field in order to continue to serve as an important reference guidance in the region. PMID: 29208158 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Sullivan AK, Sperle I, Raben D, Amato-Gauci AJ, Lundgren JD, Yazdanpanah Y, Jakobsen SF, Tavoschi L Tags: Euro Surveill Source Type: research

Reduction in undiagnosed HIV infection in the European Union/European Economic Area, 2012 to 2016.
Abstract It is well-documented that early HIV diagnosis and linkage to care reduces morbidity and mortality as well as HIV transmission. We estimated the median time from HIV infection to diagnosis in the European Union/European Economic Area (EU/EEA) at 2.9 years in 2016, with regional variation. Despite evidence of a decline in the number of people living with undiagnosed HIV in the EU/EEA, many remain undiagnosed, including 33% with more advanced HIV infection (CD4 
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: van Sighem A, Pharris A, Quinten C, Noori T, Amato-Gauci AJ, The Ecdc Hiv/Aids Surveillance And Dublin Declaration Monitoring Networks Tags: Euro Surveill Source Type: research

HIV epidemic among men who have sex with men in the Czech Republic, 2016: high time for targeted action.
e;ková B, Procházka I Abstract Reported incidence of human immunodeficiency virus (HIV) infection in the Czech Republic increased steeply over the past decade from 90 new cases in 2005 to 266 in 2015. This increase is almost exclusively attributed to sexual transmissions between men who have sex with men (MSM). In 2015, there were 79% (n=210) newly diagnosed cases among MSM, 17% (n=45) were attributed to heterosexual transmission and 1% (n=3) to people who inject drugs. Interventions targeted at MSM have not yet been prioritised in the broadly focused national HIV prevention strategy which this is en...
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Mravčík V, Pitoňák M, Hejzák R, Janíková B, Procházka I Tags: Euro Surveill Source Type: research

Hepatitis A outbreak in HIV-infected MSM and in PrEP-using MSM despite a high level of immunity, Lyon, France, January to June 2017.
up, Cotte L Abstract Since 2016, an increase in the number of hepatitis A cases affecting mainly men who have sex with men (MSM) has been reported in low endemic countries in Europe. We calculated the attack rate in Lyon, France, in populations considered at high-risk: HIV-infected MSM and HIV-negative MSM receiving HIV pre-exposure prophylaxis (PrEP). In these populations, high level of immunity did not prevent the outbreak, indicating that vaccination should be reinforced, particularly in younger individuals. PMID: 29208161 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Charre C, Ramière C, Roque-Afonso AM, Chidiac C, Zoulim F, Godinot M, Koffi J, Scholtès C, Livrozet JM, Hav Lyon Study Group, Cotte L Tags: Euro Surveill Source Type: research

Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
Abstract For over a decade virtually all A(H3N2) influenza viruses have been resistant to the adamantane class of antivirals. However, during the 2017 influenza season in Australia, 15/461 (3.3%) adamantane-sensitive A(H3N2) viruses encoding serine at residue 31 of the M2 protein were detected, more than the total number identified globally during the last 6 years. A return to wide circulation of adamantane-sensitive A(H3N2) viruses would revive the option of using these drugs for treatment and prophylaxis. PMID: 29183552 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Hurt A, Komadina N, Deng YM, Kaye M, Sullivan S, Subbarao K, Barr I Tags: Euro Surveill Source Type: research

Childhood multidrug-resistant tuberculosis in the European Union and European Economic Area: an analysis of tuberculosis surveillance data from 2007 to 2015.
Conclusions: The burden of MDR TB in children in the EU/EEA appears low, but may be underestimated owing to challenges in laboratory confirmation. Diagnostic improvements are needed for early detection and adequate treatment of MDR TB. Children previously treated for TB or of foreign origin may warrant higher attention. PMID: 29183553 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Ködmön C, van den Boom M, Zucs P, van der Werf MJ Tags: Euro Surveill Source Type: research

Molecular characterisation of human Shiga toxin-producing Escherichia coli O26 strains: results of an outbreak investigation, Romania, February to August 2016.
Discussion/conclusion: This first description of STEC O26 strains from cases in Romania showed that the isolates belonged to a diverse population. The virulence content of most strains highlighted a high risk for severe outcome in infected patients. Improving the national surveillance strategy for STEC infections in Romania needs to be further considered. PMID: 29183554 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Usein CR, Ciontea AS, Militaru CM, Condei M, Dinu S, Oprea M, Cristea D, Michelacci V, Scavia G, Zota LC, Zaharia A, Morabito S Tags: Euro Surveill Source Type: research

Enhanced Bordetella pertussis acquisition rate in adolescents during the 2012 epidemic in the Netherlands and evidence for prolonged antibody persistence after infection.
Discussion: Longitudinal studies allow a better estimation of pertussis infections in the population. A PT-IgG concentration ≥50 IU/mL as indication of recent infection may overestimate these numbers in cross-sectional serosurveillance and should be used carefully. PMID: 29183555 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: van der Lee S, Stoof SP, van Ravenhorst MB, van Gageldonk PGM, van der Maas NAT, Sanders EAM, Buisman AM, Berbers GAM Tags: Euro Surveill Source Type: research

Epidemiological information is key when interpreting whole genome sequence data - lessons learned from a large Legionella pneumophila outbreak in Warstein, Germany, 2013.
Discussion/conclusion: The outbreak was therefore likely caused by both variants of the single sequence type, which pre-existed in the environmental reservoirs. The two clusters differed by 40 alleles located in two neighbouring genomic regions of ca 42 and 26 kb. Additional analysis supported horizontal gene transfer of the two regions as responsible for the difference between the variants. Both regions comprise virulence genes and have previously been reported to be involved in recombination events. This corroborates the notion that genomic outbreak investigations should always take epidemiological information into ...
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Petzold M, Prior K, Moran-Gilad J, Harmsen D, Lück C Tags: Euro Surveill Source Type: research

Author's correction for Euro Surveill. 2017;22(43).
PMID: 29162203 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Surveillance and laboratory detection for non-polio enteroviruses in the European Union/European Economic Area, 2016.
Abstract Enteroviruses (EVs) cause severe outbreaks of respiratory and neurological disease as illustrated by EV-D68 and EV-A71 outbreaks, respectively. We have mapped European laboratory capacity for identification and characterisation of non-polio EVs to improve preparedness to respond to (re)-emerging EVs linked to severe disease. An online questionnaire on non-polio EV surveillance and laboratory detection was submitted to all 30 European Union (EU)/European Economic Area (EEA) countries. Twenty-nine countries responded; 26 conducted laboratory-based non-polio EV surveillance, and 24 included neurological infe...
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Harvala H, Jasir A, Penttinen P, Pastore Celentano L, Greco D, Broberg E Tags: Euro Surveill Source Type: research

Gastroenteritis outbreaks on cruise ships: contributing factors and thresholds for early outbreak detection.
Abstract When an increased number of acute gastroenteritis (AG) cases is detected among tourists staying at the same accommodation, outbreak management plans must be activated in a timely manner to prevent large outbreaks. Syndromic surveillance data collected between 1 January 2010 and 31 December 2013 by five seagoing cruise ships were analysed to identify attack rate thresholds for early outbreak detection. The overall incidence rate of AG was 2.81 cases per 10,000 traveller-days (95% confidence interval (CI): 0.00-17.60), while the attack rate was 19.37 cases per 10,000 travellers (95% CI: 0.00-1...
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Mouchtouri VA, Verykouki E, Zamfir D, Hadjipetris C, Lewis HC, Hadjichristodoulou C, The Eu Shipsan Act Partnership Tags: Euro Surveill Source Type: research

Authors' correction for Euro Surveill. 2017;22(27).
PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Authors' correction for Euro Surveill. 2017;22(27). Tags: Euro Surveill Source Type: research

Note from the editors: 10th European Antibiotic Awareness Day (EAAD) - raising awareness about prudent use of antimicrobials to help curb antimicrobial resistance.
PMID: 29162207 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

National laboratory-based surveillance system for antimicrobial resistance: a successful tool to support the control of antimicrobial resistance in the Netherlands.
Abstract An important cornerstone in the control of antimicrobial resistance (AMR) is a well-designed quantitative system for the surveillance of spread and temporal trends in AMR. Since 2008, the Dutch national AMR surveillance system, based on routine data from medical microbiological laboratories (MMLs), has developed into a successful tool to support the control of AMR in the Netherlands. It provides background information for policy making in public health and healthcare services, supports development of empirical antibiotic therapy guidelines and facilitates in-depth research. In addition, participation of t...
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Altorf-van der Kuil W, Schoffelen AF, de Greeff SC, Thijsen SF, Alblas HJ, Notermans DW, Vlek AL, van der Sande MA, Leenstra T, The National Amr Surveillance Study Group Tags: Euro Surveill Source Type: research

An outbreak of chickenpox in an asylum seeker centre in Italy: outbreak investigation and validity of reported chickenpox history, December 2015-May 2016.
We describe the epidemiological and laboratory investigations, control measures and validity of reported history of chickenpox infection. Serological screening of all residents and incoming asylum seekers was performed, followed by vaccine offer to all susceptible individuals without contraindication. Forty-six cases were found and 41 were associated with the outbreak. No complications, hospitalisations or deaths occurred. Serological testing was performed in 1,278 individuals and 169 were found to be susceptible, with a seroprevalence of 86.8%. A questionnaire was administered to 336 individuals consecutively attending th...
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Vairo F, Di Bari V, Panella V, Quintavalle G, Torchia S, Serra MC, Sinopoli MT, Lopalco M, Ceccarelli G, Ferraro F, Valle S, Bordi L, Capobianchi MR, Puro V, Scognamiglio P, Ippolito G, The Outbreak Investigation Group Tags: Euro Surveill Source Type: research

Letter to the editor: Livestock-associated meticillin-resistant Staphylococcus aureus (LA-MRSA), Austria, 2013.
PMID: 29162210 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Ruppitsch W, Monschein S, Lepuschitz S, Allerberger F, Springer B Tags: Euro Surveill Source Type: research

Dynamics of the pneumonic plague epidemic in Madagascar, August to October 2017.
Abstract Transmission potential and severity of pneumonic plague in Madagascar were assessed. Accounting for reporting delay, the reproduction number was estimated at 1.73. The case fatality risk was estimated as 5.5%. Expected numbers of exported cases from Madagascar were estimated across the world and all estimates were below 1 person from August to October, 2017. PMID: 29162211 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Tsuzuki S, Lee H, Miura F, Chan YH, Jung SM, Akhmetzhanov AR, Nishiura H Tags: Euro Surveill Source Type: research

Comparing antibiotic consumption between two European countries: are packages an adequate surrogate for prescriptions?
son C Abstract Defined daily doses (DDD) are the gold standard indicator for quantifying prescriptions. Since 2014, the European Centre for Disease Prevention and Control (ECDC) has also been using the number of packages per 1,000 inhabitants per day (ipd), as a surrogate for prescriptions, to report antibiotic consumption in the community and to perform comparisons between European Union (EU) countries participating in the European Surveillance of Antimicrobial Consumption Network (ESAC-Net). In 2015, consumption was reported to range across Europe from 1.0 to 4.7 packages per 1,000 ipd. Our analysis showed that ...
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Watier L, Cavalié P, Coignard B, Brun-Buisson C Tags: Euro Surveill Source Type: research

The proportion of asymptomatic infections and spectrum of disease among pregnant women infected by Zika virus: systematic monitoring in French Guiana, 2016.
Abstract Zika virus (ZIKV) infection has been associated with complications during pregnancy. Although the presence of symptoms might be a risk factor for complication, the proportion of ZIKV-infected pregnant women with symptoms remains unknown. Following the emergence of ZIKV in French Guiana, all pregnancies in the territory were monitored by RT-PCR and/or detection of ZIKV antibodies. Follow-up data collected during pregnancy monitoring interviews were analysed from 1 February to 1 June 2016. We enrolled 3,050 pregnant women aged 14-48 years and 573 (19%) had laboratory-confirmed ZIKV infection. Rash, arthralg...
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Flamand C, Fritzell C, Matheus S, Dueymes M, Carles G, Favre A, Enfissi A, Adde A, Demar M, Kazanji M, Cauchemez S, Rousset D Tags: Euro Surveill Source Type: research

Livestock-associated meticillin-resistant Staphylococcus aureus (MRSA) among human MRSA isolates, European Union/European Economic Area countries, 2013.
Abstract Currently, surveillance of livestock-associated meticillin-resistant Staphylococcus aureus (LA-MRSA) in humans in Europe is not systematic but mainly event-based. In September 2014, the European Centre for Disease Prevention and Control (ECDC) initiated a questionnaire to collect data on the number of LA-MRSA from human samples (one isolate per patient) from national/regional reference laboratories in European Union/European Economic Area (EU/EEA) countries in 2013. Identification of LA-MRSA as clonal complex (CC) 398 by multilocus sequence typing (MLST) was preferred, although surrogate methods such as s...
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Kinross P, Petersen A, Skov R, Van Hauwermeiren E, Pantosti A, Laurent F, Voss A, Kluytmans J, Struelens MJ, Heuer O, Monnet DL, The European Human LA-Mrsa Study Group Tags: Euro Surveill Source Type: research

Transmission dynamics of the ongoing chikungunya outbreak in Central Italy: from coastal areas to the metropolitan city of Rome, summer 2017.
ler S Abstract A large chikungunya outbreak is ongoing in Italy, with a main cluster in the Anzio coastal municipality. With preliminary epidemiological data, and a transmission model using mosquito abundance and biting rates, we estimated the basic reproduction number R0 at 2.07 (95% credible interval: 1.47-2.59) and the first case importation between 21 May and 18 June 2017. Outbreak risk was higher in coastal/rural sites than urban ones. Novel transmission foci could occur up to mid-November. PMID: 29113629 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Manica M, Guzzetta G, Poletti P, Filipponi F, Solimini A, Caputo B, Della Torre A, Rosà R, Merler S Tags: Euro Surveill Source Type: research

End-of-season influenza vaccine effectiveness in adults and children, United Kingdom, 2016/17.
Discussion: The findings continue to provide support for the ongoing roll-out of the paediatric vaccine programme, with a need for ongoing evaluation. The importance of effective interventions to protect the ≥ 65-year-olds remains. PMID: 29113630 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - November 1, 2017 Category: Infectious Diseases Authors: Pebody R, Warburton F, Ellis J, Andrews N, Potts A, Cottrell S, Reynolds A, Gunson R, Thompson C, Galiano M, Robertson C, Gallagher N, Sinnathamby M, Yonova I, Correa A, Moore C, Sartaj M, de Lusignan S, McMenamin J, Zambon M Tags: Euro Surveill Source Type: research

Risk of transmission of sporadic Creutzfeldt-Jakob disease by surgical procedures: systematic reviews and quality of evidence.
CONCLUSION: The association between surgery and sCJD remains uncertain. Measures currently recommended for preventing sCJD transmission should be strongly maintained. Future studies should focus on the potential association between sCJD and surgery undergone a long time previously. PMID: 29090678 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: López FJG, Ruiz-Tovar M, Almazán-Isla J, Alcalde-Cabero E, Calero M, de Pedro-Cuesta J Tags: Euro Surveill Source Type: research

Pet rodents as possible risk for leptospirosis, Belgium and France, 2009 to 2016.
Abstract Leptospirosis is an under-reported and emerging zoonotic disease which is potentially fatal in humans. Rodents are the main reservoirs for pathogenic Leptospira spp., but diagnosis in these animals is difficult, and their infection, which does not induce symptoms, usually goes unoticed. Although the exposures of most human cases of leptospirosis are poorly documented, we were able to identify six human cases of leptospirosis which were associated with direct contact with pet rodents (mice or rats) in Belgium and France between 2009 and 2016. All cases had severe disease and for all, the presence of Leptos...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Mori M, Bourhy P, Le Guyader M, Van Esbroeck M, Djelouadji Z, Septfons A, Kodjo A, Picardeau M Tags: Euro Surveill Source Type: research

VIM-1 carbapenemase-producing Escherichia coli isolated from retail seafood, Germany 2016.
Abstract Carbapenems belong to the group of last resort antibiotics in human medicine. Therefore, the emergence of growing numbers of carbapenemase-producing bacteria in food-producing animals or the environment is worrying and an important concern for the public health sector. In the present study, a set of 45 Enterobacteriaceae isolated from German retail seafood (clams and shrimps), sampled in 2016, were investigated by real-time PCR for the presence of carbapenemase-producing bacteria. One Escherichia coli (ST10), isolated from a Venus clam (Ruditapes philippinarum) harvested in the Mediterranean Sea (Italy), ...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Roschanski N, Guenther S, Vu TTT, Fischer J, Semmler T, Huehn S, Alter T, Roesler U Tags: Euro Surveill Source Type: research

Low interim influenza vaccine effectiveness, Australia, 1 May to 24 September 2017.
We present interim influenza vaccine effectiveness (VE) estimates from Australia. Adjusted VE was low overall at 33% (95% confidence interval (CI): 17 to 46), 50% (95% CI: 8 to 74) for A(H1)pdm09, 10% (95% CI: -16 to 31) for A(H3) and 57% (95% CI: 41 to 69) for influenza B. For A(H3), VE was poorer for those vaccinated in the current and prior seasons. PMID: 29090681 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Sullivan SG, Chilver MB, Carville KS, Deng YM, Grant KA, Higgins G, Komadina N, Leung VK, Minney-Smith CA, Teng D, Tran T, Stocks N, Fielding JE Tags: Euro Surveill Source Type: research

6thEurosurveillance scientific seminar 'One Health - we are in this together - Viral and bacterial diseases/conditions at the animal-human interface' at ESCAIDE 2017 in Stockholm.
PMID: 29067901 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Economic evaluation of HIV pre-exposure prophylaxis among men-who-have-sex-with-men in England in 2016.
Abstract Clinical effectiveness of pre-exposure prophylaxis (PrEP) for preventing HIV acquisition in men who have sex with men (MSM) at high HIV risk is established. A static decision analytical model was constructed to inform policy prioritisation in England around cost-effectiveness and budgetary impact of a PrEP programme covering 5,000 MSM during an initial high-risk period. National genitourinary medicine clinic surveillance data informed key HIV risk assumptions. Pragmatic large-scale implementation scenarios were explored. At 86% effectiveness, PrEP given to 5,000 MSM at 3.3 per 100 person-years annual HIV ...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Ong KJ, Desai S, Field N, Desai M, Nardone A, van Hoek AJ, Gill ON Tags: Euro Surveill Source Type: research

Measles outbreak linked to European B3 outbreaks, Wales, United Kingdom, 2017.
Abstract The United Kingdom achieved interrupted endemic measles transmission for 36 months in 2016. Despite this, ongoing challenges from sporadic measles cases typically imported from abroad remain. We summarise a B3 measles genotype outbreak in south-east Wales occurring between May and September 2017, linked with other European outbreaks, and lessons learnt. Seventeen confirmed cases and one probable case occurred principally in education and healthcare-settings. Six confirmed cases attended healthcare settings when infectious, without being isolated. PMID: 29067903 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Currie J, Davies L, McCarthy J, Perry M, Moore C, Cottrell S, Bowley M, Williams C, Shankar AG, Stiff R Tags: Euro Surveill Source Type: research

Options for affordable pre-exposure prophylaxis (PrEP) in national HIV prevention programmes in Europe.
PMID: 29067904 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Coleman R, Prins M Tags: Euro Surveill Source Type: research

Multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017.
We describe a multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Denmark, 2017. Whole genome sequencing of the strain GK124 identified MSLT ST1903, NG-MAST ST1614 and all relevant resistance determinants including similar penA resistance mutations previously described in ceftriaxone-resistant gonococcal strains. Although treatment with ceftriaxone 0.5 g plus azithromycin 2 g was successful, increased awareness of spread of gonococcal strains threatening the recommended dual therapy is crucial. PMID: 29067905 [PubMed - in pro...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Terkelsen D, Tolstrup J, Johnsen CH, Lund O, Larsen HK, Worning P, Unemo M, Westh H Tags: Euro Surveill Source Type: research

Surveillance of Zika virus infection in the EU/EEA, June 2015 to January 2017.
twork Abstract Surveillance of Zika virus (ZIKV) infection in the European Union/European Economic Area (EU/EEA) was implemented in 2016 in response to the large outbreak reported in the Americas in 2015 associated with an increased number of infants born with microcephaly. Between June 2015 and January 2017, 21 EU/EEA countries reported 2,133 confirmed cases of ZIKV infection, of whom 106 were pregnant women. Cases infected in the Caribbean constituted 71% of reported cases. Almost all cases (99%) were most probably infected by mosquito bite during travel outside continental Europe, while only 1% were transmitted...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Spiteri G, Sudre B, Septfons A, Beauté J, On Behalf Of The European Zika Surveillance Network Tags: Euro Surveill Source Type: research

Low 2016/17 season vaccine effectiveness against hospitalised influenza A(H3N2) among elderly: awareness warranted for 2017/18 season.
N, Lovric Z, Ferenczi A, I-Move Hospital Working Group, Moren A Abstract In a multicentre European hospital study we measured influenza vaccine effectiveness (IVE) against A(H3N2) in 2016/17. Adjusted IVE was 17% (95% confidence interval (CI): 1 to 31) overall; 25% (95% CI: 2 to 43) among 65-79-year-olds and 13% (95% CI: -15 to 30) among those ≥ 80 years. As the A(H3N2) vaccine component has not changed for 2017/18, physicians and public health experts should be aware that IVE could be low where A(H3N2) viruses predominate. PMID: 29043961 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Rondy M, Gherasim A, Casado I, Launay O, Rizzo C, Pitigoi D, Mickiene A, Marbus SD, Machado A, Syrjänen RK, Pem-Novose I, Horváth JK, Larrauri A, Castilla J, Vanhems P, Alfonsi V, Ivanciuc AE, Kuliese M, van Gageldonk-Lafeber R, Gomez V, Ikonen N, Lovri Tags: Euro Surveill Source Type: research

Usutu virus infections among blood donors, Austria, July and August 2017 - Raising awareness for diagnostic challenges.
Abstract Between July and August 2017, seven of 12,047 blood donations from eastern Austria, reacted positive to West Nile virus (WNV) in the cobas test (Roche). Follow-up investigations revealed Usutu virus (USUV) nucleic acid in six of these. Retrospective analyses of four blood donors diagnosed as WNV-infected in 2016 showed one USUV positive. Blood transfusion services and public health authorities in USUV-endemic areas should be aware of a possible increase of human USUV infections. PMID: 29043962 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Bakonyi T, Jungbauer C, Aberle SW, Kolodziejek J, Dimmel K, Stiasny K, Allerberger F, Nowotny N Tags: Euro Surveill Source Type: research

Call for papers for a special issue on advanced diagnostics to inform public health policy.
PMID: 29043963 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Accuracy of diagnosis criteria in patients with suspected diagnosis of sporadic Creutzfeldt-Jakob disease and detection of 14-3-3 protein, France, 1992 to 2009.
This study confirms the usefulness of the recent modification of diagnosis criteria by the addition of the results of CSF real-time quaking-induced conversion, a method based on prion seed-induced misfolding and aggregation of recombinant prion protein substrate that has proven to be a highly specific test for diagnosis of sporadic CJD. PMID: 29043964 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Peckeu L, Delasnerie-Lauprètre N, Brandel JP, Salomon D, Sazdovitch V, Laplanche JL, Duyckaerts C, Seilhean D, Haïk S, Hauw JJ Tags: Euro Surveill Source Type: research

Authors' reply: Geographic resolution of surveillance data and influenza prevention in large countries.
ource: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Authors' reply: Geographic resolution of surveillance data and influenza prevention in large countries. Tags: Euro Surveill Source Type: research

Infectious disease screening in asylum seekers: range, coverage and economic evaluation in Germany, 2015.
Abstract Screening asylum seekers for infectious diseases is widely performed, but economic evaluations of such are scarce. We performed a policy analysis and economic evaluation of such screening in Germany, and analysed the effect of screening policies on cost differences between federal states. Of the 16 states, screening was compulsory for tuberculosis (TB) in asylum seekers ≥ 16 years of age in all states as well as in children
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Bozorgmehr K, Wahedi K, Noest S, Szecsenyi J, Razum O Tags: Euro Surveill Source Type: research

Letter to the editor: Sampling bias should be minimised when analysing influenza transmission zones involving very large countries.
PMID: 29019316 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Shin GY, Manuel R Tags: Euro Surveill Source Type: research

PRECEPT: an evidence assessment framework for infectious disease epidemiology, prevention and control.
n O Abstract Decisions in public health should be based on the best available evidence, reviewed and appraised using a rigorous and transparent methodology. The Project on a Framework for Rating Evidence in Public Health (PRECEPT) defined a methodology for evaluating and grading evidence in infectious disease epidemiology, prevention and control that takes different domains and question types into consideration. The methodology rates evidence in four domains: disease burden, risk factors, diagnostics and intervention. The framework guiding it has four steps going from overarching questions to an evidence statement...
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Harder T, Takla A, Eckmanns T, Ellis S, Forland F, James R, Meerpohl JJ, Morgan A, Rehfuess E, Schünemann H, Zuiderent-Jerak T, de Carvalho Gomes H, Wichmann O Tags: Euro Surveill Source Type: research

Addendum for Euro Surveill. 2017;22(8).
PMID: 29019318 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - October 1, 2017 Category: Infectious Diseases Authors: Eurosurveillance Editorial Team Tags: Euro Surveill Source Type: research

Increase in Legionnaires' disease cases associated with travel to Dubai among travellers from the United Kingdom, Sweden and the Netherlands, October 2016 to end August 2017.
Abstract Between 1 October 2016 and 31 August 2017, 51 Legionnaires' disease (LD) cases from the United Kingdom, Sweden and the Netherlands were identified with associated travel to Dubai. Cases did not all stay in the same accommodation, indicating that no single accommodation could be the source for all these infections. While local investigations continue into other potential sources, clinicians should remain alert to the possibility of LD among travellers returning from Dubai with respiratory illness. PMID: 28935023 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 21, 2017 Category: Infectious Diseases Authors: Dabrera G, Brandsema P, Lofdahl M, Naik F, Cameron R, McMenamin J, Pebody R, Phin N Tags: Euro Surveill Source Type: research

Note from the editors: Wave goodbye and say hello - Eurosurveillance to launch new website soon.
PMID: 28935024 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 21, 2017 Category: Infectious Diseases Authors: Eurosurveillance editorial team Tags: Euro Surveill Source Type: research

Burden of salmonellosis, campylobacteriosis and listeriosis: a time series analysis, Belgium, 2012 to 2020.
Abstract Salmonellosis, campylobacteriosis and listeriosis are food-borne diseases. We estimated and forecasted the number of cases of these three diseases in Belgium from 2012 to 2020, and calculated the corresponding number of disability-adjusted life years (DALYs). The salmonellosis time series was fitted with a Bai and Perron two-breakpoint model, while a dynamic linear model was used for campylobacteriosis and a Poisson autoregressive model for listeriosis. The average monthly number of cases of salmonellosis was 264 (standard deviation (SD): 86) in 2012 and predicted to be 212 (SD: 87) in 2020; campylobacter...
Source: Euro Surveill - September 21, 2017 Category: Infectious Diseases Authors: Maertens de Noordhout C, Devleesschauwer B, Haagsma JA, Havelaar AH, Bertrand S, Vandenberg O, Quoilin S, Brandt PT, Speybroeck N Tags: Euro Surveill Source Type: research

Ongoing outbreak with well over 4,000 measles cases in Italy from January to end August 2017 - what is making elimination so difficult?
We report an ongoing measles outbreak in Italy, with over 4,400 cases reported in 20 Regions from January to August 2017. Median age was 27 years, 88% of the cases were unvaccinated. The highest incidence was in infants below one year of age and 7% of cases occurred among healthcare workers. Three deaths occurred and two cases of encephalitis were reported. Wide immunity gaps and nosocomial transmission are major challenges to measles elimination in Italy. PMID: 28933342 [PubMed - in process] (Source: Euro Surveill)
Source: Euro Surveill - September 14, 2017 Category: Infectious Diseases Authors: Filia A, Bella A, Del Manso M, Baggieri M, Magurano F, Rota MC Tags: Euro Surveill Source Type: research

The European Medical Corps: first Public Health Team mission and future perspectives.
Abstract The 2013-2016 Ebola epidemic in West Africa challenged traditional international mechanisms for public health team mobilisation to control outbreaks. Consequently, in February 2016, the European Union (EU) launched the European Medical Corps (EMC), a mechanism developed in collaboration with the World Health Organization (WHO) to rapidly deploy teams and equipment in response to public health emergencies inside and outside the EU. Public Health Teams (PHTs), a component of the EMC, consist of experts in communicable disease prevention and control from participating countries and the European Centre for Di...
Source: Euro Surveill - September 14, 2017 Category: Infectious Diseases Authors: Haussig JM, Severi E, Baum JH, Vanlerberghe V, Laiseca A, Defrance L, Brailescu C, Coulombier D, Jansa J Tags: Euro Surveill Source Type: research

First outbreak of Zika virus in the continental United States: a modelling analysis.
ler S Abstract Since 2015, Zika virus (ZIKV) has spread throughout Latin and Central America. This emerging infectious disease has been causing considerable public health concern because of severe neurological complications, especially in newborns after congenital infections. In July 2016, the first outbreak in the continental United States was identified in the Wynwood neighbourhood of Miami-Dade County, Florida. In this work, we investigated transmission dynamics using a mathematical model calibrated to observed data on mosquito abundance and symptomatic human infections. We found that, although ZIKV transmissio...
Source: Euro Surveill - September 14, 2017 Category: Infectious Diseases Authors: Marini G, Guzzetta G, Rosà R, Merler S Tags: Euro Surveill Source Type: research

Recurrent seasonal outbreak of an emerging serotype of Shiga toxin-producing Escherichia coli (STEC O55:H7 Stx2a) in the south west of England, July 2014 to September 2015.
Namara E, Hawker J, Balasegaram S Abstract The first documented British outbreak of Shiga toxin-producing Escherichia coli (STEC) O55:H7 began in the county of Dorset, England, in July 2014. Since then, there have been a total of 31 cases of which 13 presented with haemolytic uraemic syndrome (HUS). The outbreak strain had Shiga toxin (Stx) subtype 2a associated with an elevated risk of HUS. This strain had not previously been isolated from humans or animals in England. The only epidemiological link was living in or having close links to two areas in Dorset. Extensive investigations included testing of animals and...
Source: Euro Surveill - September 7, 2017 Category: Infectious Diseases Authors: McFarland N, Bundle N, Jenkins C, Godbole G, Mikhail A, Dallman T, O'Connor C, McCarthy N, O'Connell E, Treacy J, Dabke G, Mapstone J, Landy Y, Moore J, Partridge R, Jorgensen F, Willis C, Mook P, Rawlings C, Acornley R, Featherstone C, Gayle S, Edge J, M Tags: Euro Surveill Source Type: research