Outcome and Sequelae of Infectious Encephalitis
J Clin Neurol. 2024 Jan;20(1):23-36. doi: 10.3988/jcn.2023.0240.ABSTRACTAcute infectious encephalitis is a widely studied clinical syndrome. Although identified almost 100 years ago, its immediate and delayed consequences are still neglected despite their high frequency and possible severity. We reviewed the available data on sequelae and persisting symptoms following infectious encephalitis with the aim of characterizing the clinical picture of these patients at months to years after hospitalization. We searched PubMed for case series involving sequelae after infectious encephalitis. We carried out a narrative review of t...
Source: Journal of Clinical Neurology - January 5, 2024 Category: Neurology Authors: Kathryn A Kvam Jean-Paul Stahl Felicia C Chow Ariane Soldatos Pierre Tattevin James Sejvar Alexandra Mailles Source Type: research
Viruses, Vol. 16, Pages 88: Computer-Selected Antiviral Compounds: Assessing In Vitro Efficacies against Rift Valley Fever Virus
This study aimed to evaluate the in vitro efficacy of chemical compounds targeting the Gc fusion mechanism. These compounds were identified through virtual screening of millions of commercially available small molecules using a structure-based artificial intelligence bioactivity predictor. In our experiments, a pretreatment with small molecule compounds revealed that 3 out of 94 selected compounds effectively inhibited the replication of the Rift Valley fever virus MP-12 strain in Vero cells. As anticipated, these compounds did not impede viral RNA replication when administered three hours after infection. However, signifi...
Source: Viruses - January 5, 2024 Category: Virology Authors: Cigdem Alkan Terrence O ’Brien Victor Kenyon Tetsuro Ikegami Tags: Article Source Type: research
Recombinant protein immunoblots for differential diagnosis of tick-borne relapsing fever and Lyme disease
This article reviews the application of line immunoblots (IBs), where recombinant proteins applied as lines on nitrocellulose membrane strips are used to detect antibodies in patient sera, for the diagnosis and differentiation of LD and TBRF.PMID:38174512 | DOI:10.4103/0972-9062.383641 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - January 4, 2024 Category: Infectious Diseases Authors: Jyotsna S Shah Joseph J Burrascano Ranjan Ramasamy Source Type: research
Microfluidic PCR and network analysis reveals complex tick-borne pathogen interactions in the tropics
Ixodid ticks, particularly Rhipicephalus sanguineus s.l., are important vectors of various disease-causing agents in dogs and humans in Cuba. However, our understading of interactions among tick-borne pathogens (... (Source: Parasites and Vectors)
Source: Parasites and Vectors - January 4, 2024 Category: Microbiology Authors: Cristian D íaz-Corona, Lisset Roblejo-Arias, Elianne Piloto-Sardiñas, Adrian A. Díaz-Sánchez, Angélique Foucault-Simonin, Clemence Galon, Alejandra Wu-Chuang, Lourdes Mateos-Hernández, Zbigniew Zając, Joanna Kulisz, Aneta Wozniak, María Karla Cast Tags: Research Source Type: research
First detection of the Jingmen tick virus in Amblyomma testudinarium ticks from the Kanto district, Japan
This report is the first to detect JMTV in the Kanto region. Further studies are required to elucidate the potential risk of infection by this tick-borne virus in Japan. In particular, the prevalence of JMTV in wild animals should be examined to clarify its geographical distribution, host range, and transmission cycle in nature.PMID:38171848 | DOI:10.7883/yoken.JJID.2023.347 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - January 3, 2024 Category: Infectious Diseases Authors: Ryo Matsumura Daisuke Kobayashi Kyo Itoyama Haruhiko Isawa Source Type: research
First detection of the Jingmen tick virus in Amblyomma testudinarium ticks from the Kanto district, Japan
This report is the first to detect JMTV in the Kanto region. Further studies are required to elucidate the potential risk of infection by this tick-borne virus in Japan. In particular, the prevalence of JMTV in wild animals should be examined to clarify its geographical distribution, host range, and transmission cycle in nature.PMID:38171848 | DOI:10.7883/yoken.JJID.2023.347 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - January 3, 2024 Category: Infectious Diseases Authors: Ryo Matsumura Daisuke Kobayashi Kyo Itoyama Haruhiko Isawa Source Type: research
First detection of the Jingmen tick virus in Amblyomma testudinarium ticks from the Kanto district, Japan
This report is the first to detect JMTV in the Kanto region. Further studies are required to elucidate the potential risk of infection by this tick-borne virus in Japan. In particular, the prevalence of JMTV in wild animals should be examined to clarify its geographical distribution, host range, and transmission cycle in nature.PMID:38171848 | DOI:10.7883/yoken.JJID.2023.347 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - January 3, 2024 Category: Infectious Diseases Authors: Ryo Matsumura Daisuke Kobayashi Kyo Itoyama Haruhiko Isawa Source Type: research
First detection of the Jingmen tick virus in Amblyomma testudinarium ticks from the Kanto district, Japan
This report is the first to detect JMTV in the Kanto region. Further studies are required to elucidate the potential risk of infection by this tick-borne virus in Japan. In particular, the prevalence of JMTV in wild animals should be examined to clarify its geographical distribution, host range, and transmission cycle in nature.PMID:38171848 | DOI:10.7883/yoken.JJID.2023.347 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - January 3, 2024 Category: Infectious Diseases Authors: Ryo Matsumura Daisuke Kobayashi Kyo Itoyama Haruhiko Isawa Source Type: research
Preparation and characterization of inactivated tick-borne encephalitis virus samples for single-particle imaging at the European XFEL
X-ray imaging of virus particles at the European XFEL could eventually allow their complete structures to be solved, potentially approaching the resolution of other structural virology methods. To achieve this ambitious goal with today's technologies, about 1 ml of purified virus suspension containing at least 1012 particles per millilitre is required. Such large amounts of concentrated suspension have never before been obtained for enveloped viruses. Tick-borne encephalitis virus (TBEV) represents an attractive model system for the development of enveloped virus purification and concentration protocols, given the avai...
Source: Acta Crystallographica Section D - January 1, 2024 Category: Biochemistry Authors: Vorovitch, M.F. Samygina, V.R. Pichkur, E. Konarev, P.V. Peters, G. Khvatov, E.V. Ivanova, A.L. Tuchynskaya, K.K. Konyushko, O.I. Fedotov, A.Y. Armeev, G. Shaytan, K.V. Kovalchuk, M.V. Osolodkin, D.I. Egorov, A.M. Ishmukhametov, A.A. Tags: tick-borne encephalitis virus virus purification virus characterization single-particle imaging research papers Source Type: research
Tick-Borne Encephalitis, Lombardy, Italy
A. Gaffuri et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - December 31, 2023 Category: Infectious Diseases Source Type: research
