MERA India: Malaria Elimination Research Alliance India.
Authors: Rahi M, Anvikar AR, Singh OP, Jambulingam P, Vijayachari P, Das A, Pati S, Narain K, Gangakhedkar RR, Dhingra N, Bhargava B PMID: 31070158 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

ICMR research initiatives enabling malaria elimination in India.
Authors: Rahi M, Das P, Jambulingam P, Vijayachari P, Das A, Pati S, Narain K, Kumar A, Gangakhedkar RR, Valecha N PMID: 31070159 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Essential guidance on malaria elimination in its history.
Authors: Baird JK PMID: 31070160 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Partnering to fight malaria in India: Past, present and future.
Authors: Samby K, Ramachandruni H, Banerji J, Burrows JN, Daumerie PG, Hooft van Huijsduijnen RAM, Duparc S, Wells TNC Abstract The global fight against malaria requires continual development of new tools. Collaborations in India have played a key role in MMV's partnerships to discover, develop and deliver new medicines. Over the last decade, India has become a focal point of global medicinal chemistry, and combined with investments in basic science, this has led to the discovery of new potential drugs. India also brings significant experience to drug development, in clinical trials, but also in formulation and man...
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Some considerable issues concerning malaria elimination in India.
Authors: Kumar A Abstract Malaria elimination is a health priority of India for the national development and to meet UN sustainable development goals. In this article, an attempt has been made to highlight some of the key issues that need attention and consideration. These include addressing the gaps in malaria burden and adopting District Health Information System (DHIS) for real time data gathering, transfer and analysis for rapid response. The article highlights threat to malaria elimination from human migration, asymptomatic malaria, P. malariae as a neglected species, need for updating vector information and d...
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Malaria elimination in India-The way forward.
Authors: Ghosh SK, Rahi M Abstract The World Malaria Report 2018 published by the World Health Organization highlights that no significant progress in reducing global malaria cases was achieved for the period 2015-2017. India carries 4% of the global malaria burden and contributes 87% of the total malaria cases in South-East Asia. India is in malaria elimination mode, and set targets for malaria-free status by 2030. Diagnosis and treatment of asymptomatic falciparum malaria cases continues to be a challenge for health care providers. To overcome these hurdles innovative solutions along with the existing tools and s...
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Malaria control in India: A national perspective in a regional and global fight to eliminate malaria.
Authors: Guerin PJ, Dhorda M, Ganguly NK, Sibley CH Abstract Since the declaration of the vision of malaria eradication in 2007, the overall burden of malaria has been reduced substantially in many countries in the endemic world. This progress has, however, recently slowed worldwide and even an increase of morbidity and mortality has been observed in some regions. That reality has led to reflection on the strategy for malaria elimination, noting that focusing only on low transmission sites has competed with the efforts in countries that still have foci with high malaria burdens. This opinion piece outlines the coll...
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Preparedness for malaria elimination in the wake of climate change in the State of Uttarakhand (India).
Authors: Dhiman RC, Singh P, Yadav Y, Saraswat S, Kumar G, Singh RK, Ojha VP, Joshi BC, Singh P Abstract Background & objectives: Climate change is an emerging issue particularly in the context of vector-borne diseases. A study was undertaken in Nainital and Almora districts of Uttarakhand to provide evidences of changing climatic conditions, abundance of vectors, and knocking of malaria in hilly areas. Material and methods: Longitudinal data on temperature and relative humidity were procured from Tussar Silk Centre, Bhimtal, India as well as generated using HOBO device. Monthly density of malaria vectors, ...
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Malaria elimination drive in Odisha: Hope for halting the transmission.
Authors: Pradhan MM, Meherda PK PMID: 31070166 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Comprehensive case management of malaria: Operational research informing policy.
Authors: Pradhan MM, Anvikar AR, Daumerie PG, Pradhan S, Dutta A, Shah NK, Joshi PL, Banerji J, Duparc S, Mendis K, Murugasampillay S, Valecha N Abstract In 2013, the Odisha state Vector Borne Disease Control Programme led a five year operational research project, under programmatic conditions, in close collaboration with several partners. This Comprehensive Case Management Project covered a population of 900,000 across paired control and intervention blocks in four districts, each with different transmission intensities. Key gaps in access to malaria services were identified through household surveys and a detaile...
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Malaria elimination: Using past and present experience to make malaria-free India by 2030.
This article provides insights into the past and present malaria control and elimination efforts that may be useful for the national programme for eliminating malaria from India by 2030. PMID: 31070168 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Role of a dedicated support group in retaining malaria-free status of Sri Lanka.
Authors: Datta R, Mendis K, Wikremasinghe R, Premaratne R, Fernando D, Parry J, Rolfe B PMID: 31070169 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Unravelling the trends of research on malaria in India through bibliometric analysis.
Authors: Singh US, Mahanty S Abstract Background & objectives: With the development of technological know-how, in recent years, malaria research in India has advanced to a great extent and the corresponding research is being translated into the form of publications, which has started to pile in thousands over the years. The purpose of the present study was to perform a bibliometric analysis on malaria research in India from its inception. Methods: The Web of Science (WoS) platform developed by Clarivate Analytics was utilized to retrieve publications on malaria research in India. The publications were retri...
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Prevalence of submicroscopic malaria in low transmission state of Punjab: A potential threat to malaria elimination.
The objectives of the study was to explore the prevalence of sub-microscopic infections in low transmission areas of Punjab using highly sensitive molecular tool. Methods: A total of 1114 finger prick blood samples were collected through active surveillance and tested for malaria diagnosis using light microscopy, RDT and PCR. Nested PCR amplification was performed using a pair of Plasmodium genus-specific primers from the 18S rRNA small subunit gene (18S rRNA). The amplified PCR products were analysed using a 2% agarose gel, stained with ethidium bromide and observed under transilluminator. Results: Test positive r...
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Deletions in the Plasmodium falciparum histidine-rich protein 2 gene: An emerging threat to the elimination of malaria in India.
Authors: Singh V, Kojom LP PMID: 31070172 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - May 11, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Strengthening of vector control in South-East Asia: Outcomes from a WHO regional workshop.
Authors: Nagpal BN, Knox TB, Risintha P, Yadav RS, Ghosh SK, Uragayala S, Valecha N, Christophel EM, Jamsheed M PMID: 30997884 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Approaches for the successful isolation and cell culture of American Rickettsia species.
Authors: Tello-Martin R, Dzul-Rosado K, Zavala-Castro J, Lugo-Caballero C Abstract Rickettsia are intracellular vector-borne bacteria, which are the etiologic agent of severe infections that could inflict death to their host. The intracellular behaviour of Rickettsia makes the study of its genetics, proteomics and cellular processes very difficult. Hence, isolation remains an important experimental technique that permits the obtention of important yields of bacteria, useful for a broad range of experiments. Isolation of Rickettsia using passages in animals or embryonated eggs has been described for long time; howev...
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Detection and distribution of Wolbachia endobacteria in Culex quinquefasciatus populations (Diptera : Culicidae) from Metropolitan Manila, Philippines.
Authors: Carvajal TM, Capistrano JDR, Hashimoto K, Go KJD, Cruz MAIJ, Martinez MJLB, Tiopianco VSP, Amalin DM, Watanabe K Abstract Background & objectives: Culex quinquefasciatus is a peridomestic mosquito known for its ability to transmit pathogenic diseases such as filariasis and Japanese encephalitis. The development and use of novel and innovative vector control measures such as the utilization of Wolbachia, along with the existing ones, are necessary to prevent the transmission of these diseases. Studies exploring the diversity of Wolbachia, particularly in Cx. quinquefasciatus are very limited in the Phil...
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Genetic diversity and structural analysis of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (IspE) from Plasmodium falciparum.
Authors: Kadian K, Vijay S, Rawal R, Singh J, Anvikar A, Pande V, Sharma A Abstract Background & objectives: Plasmodium parasite harbours unique methylerythritol phosphate (MEP) pathway which is obligatory for the biosynthesis of isoprenoids. In malaria parasites, the isoprenoids are indispensable during hepatic, erythrocytic and gametocytic stages. Owing to the criticality of MEP pathway and the potential of its enzymes to act as antimalarial drug target, this study comprehensively investigated the genetic diversity and structural composition of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (IspE), fourth e...
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Larvicidal activity of Ricinus communis extract against mosquitoes.
Authors: Sogan N, Kapoor N, Singh H, Kala S, Nayak A, Nagpal BN Abstract Background & objectives: Vector control strategies play significant role in reducing the transmission of malaria, dengue and other vector-borne diseases. The control of vector population using synthetic insecticides has resulted in development of insecticide resistance and negative effects on humans and environment. The present investigation evaluated the larvicidal potential of methanol, dichloromethane and hexane extracts of leaves and seeds of Ricinus communis (castor) plant against the early IV instar larvae of the dengue vector, Aedes...
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Mosquito abundance and pig seropositivity as a correlate of Japanese encephalitis in human population in Assam, India.
Authors: Baruah A, Hazarika RA, Barman NN, Islam S, Gulati BR Abstract Background & objectives: Assam is the most vulnerable state for Japanese encephalitis (JE) in India. The situation warrants characterization of epidemiological patterns of JE in vectors, pigs and human population. This investigation was aimed to determine the relative abundance of mosquito species and seroprevalence of JE in pigs in order to draw an epidemiological association with reported human JE cases in Assam. Methods: Pig sera and mosquitoes from selected farms in Sivasagar and Kamrup districts of Assam were collected fortnightly f...
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Modeling spatial distribution of Rhombomys opimus as the main reservoir host of zoonotic cutaneous leishmaniasis in northeastern Iran.
Authors: Sofizadeh A, Hanafi-Bojd AA, Shoraka HR Abstract Background & objectives: Zoonotic cutaneous leishmaniasis (ZCL) is among the most endemic zoonotic diseases in Golestan Province of Iran. The aim of this study was to find the high risk areas of this infection by considering the distribution of reservoirs and human infection. Methods: A cross-sectional study was conducted, in which Rhombomys opimus (Gerbils) were captured from different collection sites across the Golestan Province, Iran. records about the occurrence of Rh. opimus in the Province was obtained from earlier studies and were gathered in...
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

First field evidence infection of Culex perexiguus by West Nile virus in Sahara Oasis of Algeria.
This study reports for the first time a WNV natural infection of Culex perexiguus in the study region indicating that species other than Cx. pipiens should be taken into consideration in WNV surveillance, especially in specific environments like Saharan Oasis ecosystem. PMID: 30997891 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

The relationship between skin rash and outcome in dengue.
This study was aimed to compare the clinical profile and outcome in DF patients with or without skin involvement. Methods: This study included all the patients with DF from the acute febrile illness database of a tertiary care health centre in south India. These patients were further subgrouped into SP and SN (skin involvement positive and negative) based on the presence and absence of skin rash. Differences in clinical presentation, laboratory parameters, disease course, morbidity and outcome among patients with DF with or without skin rash were recorded and analysed statistically. Results: In total 387 patients (...
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

High resolution melting analysis as an accurate method for identifying Leishmania infantum in canine serum samples.
This study aimed to diagnose and identify Leishmania infection caused by L. infantum species using real-time PCR coupled with HRM assay in the serum samples in comparison with anti-L. infantum antibodies obtained using direct agglutination test (DAT), in domestic and wild canines of northeastern Iran. Methods: Serum samples of 15 foxes, 14 jackals, seven domestic dogs and three wolves were collected in some villages around Shirvan and Bojnourd districts from the northeast regions of Iran during 2014-15. Initially, all the collected serum samples were tested by DAT for the detection of anti-L. infantum antibodies. After...
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Diagnostic ability of community health workers for malaria diagnosis in the field using different variants of bivalent malaria rapid diagnostic test kits.
Authors: Singh MP, Chand SK, Jaiswal A, Savargaonkar D, Anvikar AR PMID: 30997894 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Preliminary serological investigation of Rift Valley fever in Poland.
Authors: Bazanow BA, Stygar D, Romuk E, Skrzep-Poloczek B, Pacoń J, Gadzała Ł, Welz M, Pawęska JT PMID: 30997895 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Can Google be used to study parasitic disease? Internet searching on tick-borne encephalitis in Germany.
Authors: Walker MD PMID: 30997896 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Incrimination of Aedes aegypti for dengue virus serotype-1 in Assam, Northeast India.
Authors: Dutta P, Khan SA, Chetry S, Abdul M PMID: 30997897 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 20, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Geographic distribution and spatial analysis of Leishmania infantum infection in domestic and wild animal reservoir hosts of zoonotic visceral leishmaniasis in Iran: A systematic review.
The objective of this study was to review the spatial distribution of canine VL (CVL) caused by Leishmania infantum in domestic and wild canines in different geographical areas of Iran. An extensive literature search was conducted in different international and national databases, including Cochrane, MEDLINE/PubMed, Scopus, Web of Science and Iran Medex to find articles with the words "visceral leishmaniasis in Iran" in their titles and "canine visceral leishmaniasis in Iran" or "feline visceral leishmaniasis in Iran" or "accidental reservoir hosts of visceral leishmaniasis in Iran" ...
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

A laboratory simulation study on suppression of resistance genes by differential exposures to an insecticide in Anopheles stephensi Liston population.
Authors: Verma V, Agrawal OP, Velamuri PS, Raghavendra K Abstract Background & objectives: : Insecticide applied at optimum dosage and coverage delays the development of resistance in disease vectors. The study was aimed to test the hypothesis whether decrease in exposure to insecticide leads to decrease in selection of insecticide resistance in mosquitoes. The mosquitoes were variably exposed to insecticide in the laboratory by simulating the variations in insecticide sprays applied in the field. Methods: : The study was carried out on DDT resistant adults of Anopheles stephensi. Mosquitoes were differenti...
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Prevalence of disease vectors in Lakshadweep Islands during post-monsoon season.
Authors: Krishnan J, Mathiarasan L Abstract Background & objectives: : Increase of vector-borne diseases (VBDs) in India has posed a question on the situation in Lakshadweep Islands, where VBDs are reported from time-to-time. The present investigation was aimed to assess the faunastic situation of the prevailing vectors along with their breeding sites in different islands of the Lakshadweep. Methods: : Extensive surveys were carried out from November 2017 to January 2018 (post-monsoon season) randomly in the nine inhabited islands of Lakshadweep for conducting faunastic studies on mosquitoes and to know the...
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Comparison of the effectiveness of two-dose versus three-dose sulphadoxine-pyrimethamine in preventing adverse pregnancy outcomes in Nigeria.
This study evaluated the effectiveness of two-dose versus three-dose of SP for IPTp-SP in the prevention of low birth weight (LBW) and malaria parasitaemia. Methods: : An open, randomized, controlled, longitudinal trial was conducted in a secondary level hospital in Nsukka region of Enugu State, Nigeria. A sample of 210 pregnant women within gestational ages of 16-24 wk were recruited at antenatal clinics and equally randomized to either a two-dose SP or three-dose SP group. The primary endpoints were LBWs, peripheral, and placental parasitaemia, while the secondary endpoints were maternal anaemia, pre-term birth, clin...
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Changing paradigm in the epidemiology of Japanese encephalitis in a non-endemic region.
This study was aimed to investigate the prevalence of JEV in mosquitoes and humans in the Thanjavur district, a non-endemic region for JE, in Tamil Nadu, by using standard available assays. Methods: : A sero-surveillance study was conducted in Thanjavur district among the normal rural school children in the 5-12 yr age group, during the JE season (October) and post-JE season (February) from 2011 to 2013 for the detection of JEV infection. Vector abundance studies were carried out from 2011 to 2014. JE seropositivity and its association between the seasons were analysed statistically. Results: : The occurrence of JE...
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Spatial risk analysis on occurrences and dispersal of Biomphalaria straminea in and endemic area for schistosomiasis.
Authors: Gomes ECS, Mesquitta MCDS, Wanderley LB, de Melo FL, de Paula Souza E Guimarães RJ, Barbosa CS Abstract Background & objectives: : Schistosomiasis is a rural endemic disease that has been expanding to urban and coastal areas in the state of Pernambuco, Brazil. The aim of this study was to characterize the distribution of breeding sites of the causative vector, Biomphalaria straminea in an endemic municipality for schistosomiasis and to present the predictive models for occurrences and dispersal of this vector snail to new areas. Methods: : A malacological survey was conducted during January ...
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Evaluation of epidemiological, clinical, and laboratory characteristics and mortality rate of patients with Crimean-Congo hemorrhagic fever in the northeast region of Turkey.
The objective of this study was to evaluate the demographic, clinical, and laboratory characteristics and mortality rates of CCHF patients in the northeast region of Turkey. Methods: : A total of 206 patients, diagnosed with CCHF, from northeast region of Turkey were included and evaluated between 2011 and 2017. Real-time reverse transcriptase polymerase chain reaction (RT-PCR) and immunofluorescence (IFA) methods were used for the diagnoses. Results: : Of the patients included in the study, 77.2% were farmers/livestockers, while 22.8% had other occupations. The incidence of tick bite or tick contact with bare hand...
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Babesiosis prevalence in malaria-endemic regions of Colombia.
Authors: Gonzalez J, Echaide I, Pabón A, Gabriel Piñeros JJ, Blair S, Tobón-Castaño A Abstract Background & objectives: : The presence of Babesia spp in humans, bovine cattle and ticks (the transmitting vector) has not been well characterized in Colombia. Babesia infection in humans can be overlooked due to similarity of the disease symptoms with malaria specially in the regions where malaria is endemic. The aim of the present work was to study the frequency of Babesia infection in humans, bovines and ticks in a malaria endemic region of Colombia, and explore the possible relationshi...
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Low susceptibility of domestic cats to experimental Leishmania infantum infection.
In this study, the susceptibility of domestic cats to experimental Leishmania infantum infection was assessed by different diagnostic methods. Methods: : A total of 12 healthy adult male cats were captured by double door live trap cages containing baits. Of them eight cats were intraperitoneally inoculated with 107 L. infantum promastigotes (stationary phase), and four cats were used as controls. Whole blood and serum samples were collected at weekly intervals for 16 wk after inoculation for testing by polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA) methods. Aspirates of prescapular lymph ...
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Adaptation of Aedes aegypti to salinity: Characterized by larger anal papillae in larvae.
Authors: Surendran SN, Sivabalakrishnan K, Jayadas TTP, Santhirasegaram S, Laheetharan A, Senthilnanthanan M, Ramasamy R Abstract PMID: 30618451 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Attempt to uncover reservoirs of human spotted fever rickettsiosis on the Fleurieu Peninsula, South Australia.
Authors: Taggart PL, Traub R, Fui S, Weinstein P Abstract PMID: 30618452 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

An investigation about the possible role of cattle and goats as reservoir hosts for Leishmania donovani in Bangladesh.
Authors: Alam MZ, Rahman MM, Akter S, Talukder MH, Dey AR Abstract PMID: 30618453 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Protein tyrosine phosphatase, opisthorchiasis and dengue: A proteomics interrelationship.
Authors: Yasri S, Wiwanitkit V Abstract PMID: 30618454 [PubMed - in process] (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - January 10, 2019 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Role of gut inhabitants on vectorial capacity of mosquitoes.
In this study, microbiome of the three genera of mosquitoes, namely Aedes, Anopheles, and Culex along with their vectorial capacity have been reviewed for assessing their role in mosquito control and transmission. Relevant articles were accessed using different databases, including LILACS, Embase, Science Direct and PubMed from inception to June 2017. The search keywords included "Aedes", "Anopheles", "Culex", "gut inhabitants", "vectors", and "mosquito". The titles, abstract, and keywords of the retrieved articles were screened, and eligible research articles wer...
Source: Journal of Vector Borne Diseases - October 4, 2018 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Predictive and diagnostic test accuracy of ultrasonography in differentiating severe dengue from nonsevere dengue.
The objective of this systematic review was to evaluate the diagnostic test accuracy of ultrasonography in differentiating severe dengue from nonsevere dengue; and to assess if ultrasonography/ultrasound can be used as a predictive (screening) and diagnostic tool in the course of dengue infection. An electronic search was conducted in different databases via OvidSP platform. The included studies were cohort studies between 1995 and 2016 wherein cases were confirmed by dengue blood test. Severity of dengue was assessed and compared using standard WHO references. The methodological quality of the paper was assessed by two in...
Source: Journal of Vector Borne Diseases - October 4, 2018 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Transcriptional responses of attractin gene in the mosquito Anopheles culicifacies: A synergistic neuro-olfactory regulation.
Authors: Das De T, Hasija Y, Dixit R Abstract Background & objectives: Attractin, is a large multi-domain protein which has regulatory functions in multiple physiological processes and thus have strong therapeutic potential. In invertebrates, it was first identified as a water-borne protein pheromone that plays important role in chemical communication and coordinates reproductive activities. But its role in mosquitoes/insects remains unknown. Our unexpected discovery of attractin homolog from the olfactory tissue of Anopheles culicifacies mosquito prompted us to investigate the possible role of Ac-attractin (Ac...
Source: Journal of Vector Borne Diseases - October 4, 2018 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Comparative proteomics of salivary glands of Anopheles culicifacies mosquitoes using tandem mass tag (TMT) mass spectrometry.
Authors: Rawal R, Vijay S, Kadian K, Adak T, Pande V, Sharma A Abstract Background & objectives: Salivary gland proteins play a pivotal role in blood feeding, epithelial interactions, and parasite transmission in mosquito vectors. Anopheles culicifacies is a complex of five sibling species, viz. A, B, C, D, and E, with diverse geographical distribution patterns. Among these, sibling species B has been identified as poor vector. Exploring the differentially expressed salivary proteins in An. culicifacies may potentially identify refractoriness factors during malaria parasite maturation and may help to elucidate ...
Source: Journal of Vector Borne Diseases - October 4, 2018 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Potent antileishmanial activity of chitosan against Iranian strain of Leishmania major (MRHO/IR/75/ER): In vitro and in vivo assay.
Authors: Esboei BR, Mohebali M, Mousavi P, Fakhar M, Akhoundi B Abstract Background & objectives: Leishmaniasis is one of the major neglected zoonotic parasitic diseases whose treatment and control is very complex. Pentavalent antimonials remain the primary drugs against different forms of leishmaniasis, however, resistance to antimony and its toxic effects has necessitated the development of alternative medications such as use of medicinal plants and natural compounds. The aim of the current study was to assess the in vitro and in vivo activities of chitosan as a natural resource against Leishmania major. ...
Source: Journal of Vector Borne Diseases - October 4, 2018 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Schistosoma mansoni infection in human and nonhuman primates in selected areas of Oromia Regional State, Ethiopia.
The objective of this study was, therefore, to determine the prevalence of S. mansoni infection in human and NHPs living in close proximities to villages in selected endemic areas of Ethiopia. Methods: In this cross-sectional study, stool specimens were collected from 911 humans, and fresh faecal droppings from 106 NHPs from Bochesa (Ziway), Bishan Gari (Kime) and Finchaa (Camp 7) endemic localities in Oromia Regional State, and examined for S. mansoni and other helminth infections using Kato-Katz method for human participants and direct microscopic examination for NHPs. Results: The prevalence of helminthiasis amo...
Source: Journal of Vector Borne Diseases - October 4, 2018 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Small-scale (Phase II) evaluation of the efficacy and residual activity of SumiShield ® 50 WG (clothianidin 50%, w/w) for indoor residual spraying in comparison to deltamethrin, bendiocarb and pirimiphos-methyl for malaria vector control in Karnataka state, India.
Small-scale (Phase II) evaluation of the efficacy and residual activity of SumiShield® 50 WG (clothianidin 50%, w/w) for indoor residual spraying in comparison to deltamethrin, bendiocarb and pirimiphos-methyl for malaria vector control in Karnataka state, India. J Vector Borne Dis. 2018 Apr-Jun;55(2):122-129 Authors: Sreehari U, Raghavendra K, Tiwari SN, Sreedharan S, Ghosh SK, Valecha N Abstract Background & objectives: There is an urgent need of introducing new insecticide molecules with novel modes of action to counter the ever growing insecticide-resistance in mosquito vectors. In the pres...
Source: Journal of Vector Borne Diseases - October 4, 2018 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research

Coinfections as an aetiology of acute undifferentiated febrile illness among adult patients in the sub-Himalayan region of north India.
The objective of the present study was to assess the prevalence of coinfections among patients with acute undifferentiated fevers (AUF) admitted in a tertiary care hospital in the northern hilly state of Himachal Pradesh, India. Methods: This was a hospital based open cohort study conducted over a period of two months (September and October) in 2016. All the patients above the age of 18 yr admitted in medical wards and fulfilling the definition of AUF were included. The patients diagnosed with dual infections were the subjects of the study. Standard guidelines were used for case definitions of scrub typhus, dengue, chi...
Source: Journal of Vector Borne Diseases - October 4, 2018 Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research