Crimean-Congo Hemorrhagic Fever Virus for Clinicians-Diagnosis, Clinical Management, and Therapeutics
Emerg Infect Dis. 2024 May;30(5):864-873. doi: 10.3201/eid3005.231648.ABSTRACTCrimean-Congo hemorrhagic fever virus (CCHFV) is the most geographically widespread tickborne viral infection worldwide and has a fatality rate of up to 62%. Despite its widespread range and high fatality rate, no vaccines or treatments are currently approved by regulatory agencies in the United States or Europe. Supportive treatment remains the standard of care, but the use of antiviral medications developed for other viral infections have been considered. We reviewed published literature to summarize the main aspects of CCHFV infection in human...
Source: Emerging Infectious Diseases - April 26, 2024 Category: Infectious Diseases Authors: Maria G Frank Gretchen Weaver Vanessa Raabe State of the Clinical Science Working Group of the National Emerging Pathogens Training Education Center ’s Special Pathogens Research Network2 State of the Clinical Science Working Group of the National Emerg Source Type: research
Crimean-Congo Hemorrhagic Fever Virus for Clinicians-Epidemiology, Clinical Manifestations, and Prevention
Emerg Infect Dis. 2024 May;30(5):854-863. doi: 10.3201/eid3005.231647.ABSTRACTCrimean-Congo hemorrhagic fever (CCHF) is a tickborne infection that can range from asymptomatic to fatal and has been described in >30 countries. Early identification and isolation of patients with suspected or confirmed CCHF and the use of appropriate prevention and control measures are essential for preventing human-to-human transmission. Here, we provide an overview of the epidemiology, clinical features, and prevention and control of CCHF. CCHF poses a continued public health threat given its wide geographic distribution, potential to spr...
Source: Emerging Infectious Diseases - April 26, 2024 Category: Infectious Diseases Authors: Maria G Frank Gretchen Weaver Vanessa Raabe State of the Clinical Science Working Group of the National Emerging Pathogens Training Education Center ’s Special Pathogens Research Network2 State of the Clinical Science Working Group of the National Emerg Source Type: research
Crimean Congo Hemorrhagic Fever Virus for Clinicians-Virology, Pathogenesis, and Pathology
Emerg Infect Dis. 2024 May;30(5):847-853. doi: 10.3201/eid3005.231646.ABSTRACTCrimean-Congo hemorrhagic fever (CCHF), caused by CCHF virus, is a tickborne disease that can cause a range of illness outcomes, from asymptomatic infection to fatal viral hemorrhagic fever; the disease has been described in >30 countries. We conducted a literature review to provide an overview of the virology, pathogenesis, and pathology of CCHF for clinicians. The virus life cycle and molecular interactions are complex and not fully described. Although pathogenesis and immunobiology are not yet fully understood, it is clear that multiple pro...
Source: Emerging Infectious Diseases - April 26, 2024 Category: Infectious Diseases Authors: Maria G Frank Gretchen Weaver Vanessa Raabe State of the Clinical Science Working Group of the National Emerging Pathogens Training and Education Center ’s Special Pathogens Research Network Source Type: research
Study of the clinical manifestations and risk factors in people affected during the first Kyasanur Forest Disease outbreak in Goa, India: A mixed method study
CONCLUSION: The 'One Health' approach should be implemented to control KFD. Tick bite prevention measures coupled with vaccination of high-risk groups and intensive health education should be carried out, especially before the transmission season. There is a need to have high clinical suspicion for KFD in the region bearing in mind the non-hemorrhagic manifestation in this outbreak.PMID:38648403 | DOI:10.4103/0972-9062.383650 (Source: Journal of Vector Borne Diseases)
Source: Journal of Vector Borne Diseases - April 22, 2024 Category: Infectious Diseases Authors: Shubham Pai Kuchelkar Amit Dias Edwin Gomes Lydia Dias Source Type: research
Tick-Borne Diseases
Emerg Med Clin North Am. 2024 May;42(2):287-302. doi: 10.1016/j.emc.2024.01.004. Epub 2024 Feb 29.ABSTRACTTicks are responsible for the vast majority of vector-borne illnesses in the United States. The number of reported tick-borne disease (TBD) cases has more than doubled in the past 20 years. The majority of TBD cases occur in warm weather months in individuals with recent outdoor activities in wooded areas. The risk of contracting a TBD is also highly dependent on geographic location. Between 24 and 48 hours of tick attachment is required for most disease transmission to occur. Only 50% to 70% of patients with a TBD wil...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Wesley Eilbert Andrew Matella Source Type: research
Tick-Borne Diseases
Emerg Med Clin North Am. 2024 May;42(2):287-302. doi: 10.1016/j.emc.2024.01.004. Epub 2024 Feb 29.ABSTRACTTicks are responsible for the vast majority of vector-borne illnesses in the United States. The number of reported tick-borne disease (TBD) cases has more than doubled in the past 20 years. The majority of TBD cases occur in warm weather months in individuals with recent outdoor activities in wooded areas. The risk of contracting a TBD is also highly dependent on geographic location. Between 24 and 48 hours of tick attachment is required for most disease transmission to occur. Only 50% to 70% of patients with a TBD wil...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Wesley Eilbert Andrew Matella Source Type: research
Tick-Borne Diseases
Emerg Med Clin North Am. 2024 May;42(2):287-302. doi: 10.1016/j.emc.2024.01.004. Epub 2024 Feb 29.ABSTRACTTicks are responsible for the vast majority of vector-borne illnesses in the United States. The number of reported tick-borne disease (TBD) cases has more than doubled in the past 20 years. The majority of TBD cases occur in warm weather months in individuals with recent outdoor activities in wooded areas. The risk of contracting a TBD is also highly dependent on geographic location. Between 24 and 48 hours of tick attachment is required for most disease transmission to occur. Only 50% to 70% of patients with a TBD wil...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Wesley Eilbert Andrew Matella Source Type: research
Tick-Borne Diseases
Emerg Med Clin North Am. 2024 May;42(2):287-302. doi: 10.1016/j.emc.2024.01.004. Epub 2024 Feb 29.ABSTRACTTicks are responsible for the vast majority of vector-borne illnesses in the United States. The number of reported tick-borne disease (TBD) cases has more than doubled in the past 20 years. The majority of TBD cases occur in warm weather months in individuals with recent outdoor activities in wooded areas. The risk of contracting a TBD is also highly dependent on geographic location. Between 24 and 48 hours of tick attachment is required for most disease transmission to occur. Only 50% to 70% of patients with a TBD wil...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Wesley Eilbert Andrew Matella Source Type: research
Tick-Borne Diseases
Emerg Med Clin North Am. 2024 May;42(2):287-302. doi: 10.1016/j.emc.2024.01.004. Epub 2024 Feb 29.ABSTRACTTicks are responsible for the vast majority of vector-borne illnesses in the United States. The number of reported tick-borne disease (TBD) cases has more than doubled in the past 20 years. The majority of TBD cases occur in warm weather months in individuals with recent outdoor activities in wooded areas. The risk of contracting a TBD is also highly dependent on geographic location. Between 24 and 48 hours of tick attachment is required for most disease transmission to occur. Only 50% to 70% of patients with a TBD wil...
Source: The Medical Clinics of North America - April 19, 2024 Category: General Medicine Authors: Wesley Eilbert Andrew Matella Source Type: research
Viruses, Vol. 16, Pages 637: Identification of New Microfoci and Genetic Characterization of Tick-Borne Encephalitis Virus Isolates from Eastern Germany and Western Poland
Conclusions: Although there are still only a few cases are reported from these areas, people spending much time outdoors should consider TBE vaccination. (Source: Viruses)
Source: Viruses - April 19, 2024 Category: Virology Authors: Nina Kr ól Lidia Chitimia-Dobler Gerhard Dobler Dorota Kiewra Aleksandra Czu łowska Anna Obiegala Joanna Zajkowska Thomas Juretzek Martin Pfeffer Tags: Article Source Type: research
Multi-locus sequence analysis of Anaplasma bovis in goats and ticks from Thailand, with the initial identification of an uncultured Anaplasma species closely related to Anaplasma phagocytophilum-like 1
This study aimed to undertake a genetic analysis of A. bovis and determine its prevalence in goats and ticks utilizing three genetic markers (16S rRNA, gltA, groEL). A total of 601 goat blood and 118 tick samples were collected from 12 sampling sites throughout Thailand. Two tick species, Haemaphysalis bispinosa (n = 109), and Rhipicephalus microplus (n = 9) were identified. The results herein showed that 13.8 % (83/601) of goats at several farms and 5 % (1/20) of ticks were infected with A. bovis. Among infected ticks, A. bovis and an uncultured Anaplasma sp. which are closely related to A. phagocytophilum-like 1, were de...
Source: Comparative immunology, microbiology and infectious diseases. - April 18, 2024 Category: Allergy & Immunology Authors: Aung Aung Duriyang Narapakdeesakul Apinya Arnuphapprasert Yudhi Ratna Nugraheni Chaiyawan Wattanachant Winai Kaewlamun Morakot Kaewthamasorn Source Type: research
