Inhibition of green tea polyphenol EGCG((-)-epigallocatechin-3-gallate) on the proliferation of gastric cancer cells by suppressing canonical wnt/β-catenin signalling pathway.
This study raises a new insight into gastric cancer prevention and therapy, and provides evidence that green tea could be used as a nutraceutical beverage.
PMID: 27338284 [PubMed - as supplied by publisher] (Source: International Journal of Food Sciences and Nutrition)
Source: International Journal of Food Sciences and Nutrition - June 26, 2016 Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
Systematic review of green tea epigallocatechin gallate in reducing low-density lipoprotein cholesterol levels of humans.
Authors: Momose Y, Maeda-Yamamoto M, Nabetani H
Abstract
We conducted a systematic review of the literature for the ability of green tea epigallocatechin gallate (EGCG) to lower low-density lipoprotein cholesterol (LDL-C). Study subjects were limited to healthy individuals and randomized, controlled trials on human serum lipid levels, especially LDL-C, conducted. A total of 17 trials (n = 1356) met all of the inclusion criteria. According to weighted mean differences for changes from baseline with 95% confidence intervals (CI), 107-856 mg/d of EGCG for 4 to 14 weeks reduced LDL-C by -9.29 mg/dl (95...
Source: International Journal of Food Sciences and Nutrition - June 23, 2016 Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
Comparative Assessment of Copper, Iron, and Zinc Contents in Selected Indian (Assam) and South African (Thohoyandou) Tea (Camellia sinensis L.) Samples and Their Infusion: A Quest for Health Risks to Consumer.
Abstract
The current study aims to assess the infusion pattern of three important micronutrients namely copper (Cu), iron (Fe), and zinc (Zn) contents from black tea samples produced in Assam (India) and Thohoyandou (South Africa). Average daily intakes and hazardous quotient were reported for these micronutrients. Total content for Cu, Fe, and Zn varied from 2.25 to 48.82 mg kg(-1), 14.75 to 148.18 mg kg(-1), and 28.48 to 106.68 mg kg(-1), respectively. The average contents of each of the three micronutrients were higher in tea leaves samples collected from South Africa than those from India while t...
Source: Biological Trace Element Research - June 22, 2016 Category: Biology Authors: Karak T, Paul RK, Kutu FR, Mehra A, Khare P, Dutta AK, Bora K, Boruah RK Tags: Biol Trace Elem Res Source Type: research
Facile Separation of 5 ‐O‐Galloylquinic Acid from Chinese Green Tea Extract using Mesoporous Zirconium Phosphate
ConclusionA facile method to separate 5‐O‐galloylquinic acid from Chinese green tea extract using m‐ZrP was established. Copyright © 2016 John Wiley & Sons, Ltd. (Source: Phytochemical Analysis)
Source: Phytochemical Analysis - June 16, 2016 Category: Biochemistry Authors: Yilong Ma, Yafang Shang, Danye Zhu, Caihong Wang, Zhifeng Zhong, Ziyang Xu Tags: Research article Source Type: research
Facile Separation of 5‐O‐Galloylquinic Acid from Chinese Green Tea Extract using Mesoporous Zirconium Phosphate
ConclusionA facile method to separate 5‐O‐galloylquinic acid from Chinese green tea extract using m‐ZrP was established. Copyright © 2016 John Wiley & Sons, Ltd. (Source: Phytochemical Analysis)
Source: Phytochemical Analysis - June 16, 2016 Category: Biochemistry Authors: Yilong Ma, Yafang Shang, Danye Zhu, Caihong Wang, Zhifeng Zhong, Ziyang Xu Tags: Research article Source Type: research
Biophysical characteristics of proteins and living cells exposed to the green tea polyphenol epigallocatechin-3-gallate (EGCg): review of recent advances from molecular mechanisms to nanomedicine and clinical trials.
Abstract
Herbs and traditional medicines have been applied for thousands of years, but researchers started to study their mode of action at the molecular, cellular and tissue levels only recently. Nowadays, just like in ancient times, natural compounds are still determining factors in remedies. To support this statement, the recently won Nobel Prize for an anti-malaria agent from the plant sweet wormwood, which had been used to effectively treat the disease, could be mentioned. Among natural compounds and traditional Chinese medicines, the green tea polyphenol epigallocatechin gallate (EGCg) is one of the ...
Source: European Biophysics Journal : EBJ - June 15, 2016 Category: Physics Authors: Peter B, Bosze S, Horvath R Tags: Eur Biophys J Source Type: research
Assessing the effects of a short-term green tea intervention in skin microvascular function and oxygen tension in older and younger adults
In conclusion, we observed statistically-significant improvements in microvascular function and skin oxygen tension. Our results suggest that green tea may prove beneficial as a dietary element in lifestyle interventions aiming to lower cardiovascular disease risk, in both older and younger populations. (Source: Microvascular Research)
Source: Microvascular Research - June 15, 2016 Category: Biochemistry Source Type: research
The behaviour of green tea catechins in a full-fat milk system under conditions mimicking the cheesemaking process.
Authors: Rashidinejad A, Birch EJ, Everett DW
Abstract
Due to their well-known health benefits, green tea catechins have received recent attention as natural additives in foods such as dairy products. However, they may present some irreversible associations with milk components (e.g. protein and milk fat globules). To investigate the behaviour of two important green tea catechins, (+)-catechin (C) and (-)-epigallocatechin gallate (EGCG), in a standard whole milk system under the conditions of cheesemaking, 250 and 500 ppm of each catechin were added to whole milk (3.3% fat). Although both C and EGCG at e...
Source: International Journal of Food Sciences and Nutrition - June 12, 2016 Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
2-DE combined with two-layer feature selection accurately establishes the origin of oolong tea.
In this study, we investigated whether two-dimensional gel electrophoresis (2-DE) and nanoscale liquid chromatography/tandem mass spectroscopy (nano-LC/MS/MS) coupled with a two-layer feature selection mechanism comprising information gain attribute evaluation (IGAE) and support vector machine feature selection (SVM-FS) are useful in identifying characteristic proteins that can be used as markers of the original source of oolong tea. Samples in this study included oolong tea leaves from 23 different sources. We found that our method had an accuracy of 95.5% in correctly identifying the origin of the leaves. Overall, our me...
Source: Genomics Proteomics ... - June 12, 2016 Category: Genetics & Stem Cells Authors: Chien HJ, Chu YW, Chen CW, Juang YM, Chien MW, Liu CW, Wu CC, Tzen JT, Lai CC Tags: Food Chem Source Type: research
Microbial decontamination of gamma irradiated black tea and determination of major minerals in black tea, fresh tea leaves and tea garden soil
Publication date: November 2016 Source:LWT - Food Science and Technology, Volume 73 Author(s): Md. Harunur Rashid, M. Alamgir Zaman Chowdhury, Zeenath Fardous, E.M. Tanvir, M. Kamruzzaman Pramanik, Israt Jahan, Md. Khorshed Alam, Mohammed Moniruzzaman, Siew Hua Gan The purpose of this research was to establish an effective dose of gamma irradiation to eliminate any possible bacterial contamination as well as assess the levels of essential major elements [sodium (Na), potassium (K), calcium (Ca), magnesium (Mg) and iron (Fe)] present in black tea. The samples were compared to fresh tea leaves and soil ...
Source: LWT Food Science and Technology - June 11, 2016 Category: Food Science Source Type: research
Characterization of functional proteases from flowers of tea (Camellia sinensis) plants
This study provides evidence of occurrences of proteases in tea flowers for the first time and an effective approach to improve contents of amino acids of tea infusion. (Source: Journal of Functional Foods)
Source: Journal of Functional Foods - June 10, 2016 Category: Nutrition Source Type: research
Effect of Tea Catechins on Folate Analysis in Green Tea by Microbiological Assay.
Authors: Umegaki K, Sekine Y, Sato Y, Chiba T, Sonoda M
Abstract
Green tea is thought to be a primary source of folate in the Japanese diet, based on folate content analyzed by a microbiological assay. Green tea also contains high amount of catechins, in particular, epigallocatechin gallate (EGCg), which was demonstrated to be able to inhibit the digestive enzyme activities and microbial growth in the folate assay. In the present study, we examined whether tea catechins interfered with components of the folate assay for green tea. A marked inhibitory effect of EGCg on microbial growth was observed at an in...
Source: Journal of Nutritional Science and Vitaminology - June 9, 2016 Category: Nutrition Tags: J Nutr Sci Vitaminol (Tokyo) Source Type: research
Polyphenol- and fibre-rich dried fruits with green tea attenuate starch-derived postprandial blood glucose and insulin: a randomised, controlled, single-blind, cross-over intervention.
Abstract
Polyphenol- and fibre-rich foods (PFRF) have the potential to affect postprandial glycaemic responses by reducing glucose absorption, and thus decreasing the glycaemic response of foods when consumed together. A randomised, single-blind, cross-over study was conducted on sixteen healthy volunteers to test whether PFRF could attenuate postprandial blood glucose in healthy volunteers when added to a source of carbohydrate (starch in bread). This is the first study to examine the effects of a meal comprised of components to inhibit each stage of the biochemical pathway, leading up to the appearance o...
Source: The British Journal of Nutrition - June 8, 2016 Category: Nutrition Authors: Nyambe-Silavwe H, Williamson G Tags: Br J Nutr Source Type: research
Oxidized tea polyphenols prevent lipid accumulation in liver and visceral white adipose tissue in rats
Conclusion
Our results suggest that OTPs alleviate the accumulation of lipids in liver and visceral white adipose tissue and promote lipid excretion in rats in vivo. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - June 6, 2016 Category: Nutrition Source Type: research
Correlation of In Vivo and In Vitro Assay Results for Assessment of Free Radical Scavenging Activity of Green Tea Nutraceuticals
In this study, an orthogonal analysis protocol was designed to evaluate the photostability of a model green tea nutraceutical formulation. Lack of agreement between chemical assay results required correlation to in vivo activity in animal model. Results indicated that photodegraded green tea samples were not only ineffective but also harmful to biological systems. Photodegradation products exerted prooxidant effect rather than the beneficial antioxidant effect. Results of the study confirmed that inappropriate selection of analysis techniques and lack of correlation between in vitro and in vivo assay results might lead to ...
Source: Journal of Food Science - May 31, 2016 Category: Food Science Authors: Heba‐Alla H. Abd‐ElSalam, Medhat A. Al‐Ghobashy, Muhammad Al‐Shorbagy, Noha Nassar, Hala E. Zaazaa, Mohamed A. Ibrahim Tags: C: Food Chemistry Source Type: research
