Comprehensive arginine metabolomics and peripheral vasodilatory capacity in rheumatoid arthritis: A monocentric cross-sectional study
Publication date: Available online 2 July 2020Source: Microvascular ResearchAuthor(s): Gian Luca Erre, Arduino Aleksander Mangoni, Giuseppe Passiu, Stefania Bassu, Floriana Castagna, Ciriaco Carru, Matteo Piga, Angelo Zinellu, Salvatore Sotgia (Source: Microvascular Research)
Source: Microvascular Research - July 3, 2020 Category: Biochemistry Source Type: research

The CX3CL1/CX3CR1 axis is up-regulated in chronic kidney disease and contributes to angiotensin II-induced migration of vascular smooth muscle cells
Publication date: Available online 29 June 2020Source: Microvascular ResearchAuthor(s): Chengsheng Li, Xiaoyi Zhong, Wenyu Xia, Jin He, Hua Gan, HongFei Zhao, Yunfeng Xia (Source: Microvascular Research)
Source: Microvascular Research - June 30, 2020 Category: Biochemistry Source Type: research

Conjunctival microvascular responses to anti-inflammatory treatment in patients with dry eye
Publication date: Available online 29 June 2020Source: Microvascular ResearchAuthor(s): Yuqing Deng, Wan Chen, Peng Xiao, Hong Jiang, Jianhua Wang, Weirong Chen, Saiqun Li, Jing Zhong, Lulu Peng, Qian Wang, Jin Yuan (Source: Microvascular Research)
Source: Microvascular Research - June 30, 2020 Category: Biochemistry Source Type: research

Nailfold capillaroscopy in common non-rheumatic conditions: A systematic review and applications for clinical practice
Publication date: Available online 27 June 2020Source: Microvascular ResearchAuthor(s): Jacopo Ciaffi, Nerenxa Ajasllari, Luana Mancarella, Veronica Brusi, Riccardo Meliconi, Francesco Ursini (Source: Microvascular Research)
Source: Microvascular Research - June 28, 2020 Category: Biochemistry Source Type: research

2-Deoxy-d-ribose (2dDR) upregulates vascular endothelial growth factor (VEGF) and stimulates angiogenesis
Publication date: Available online 25 June 2020Source: Microvascular ResearchAuthor(s): Serkan Dikici, Anthony J. Bullock, Muhammad Yar, Frederik Claeyssens, Sheila MacNeil (Source: Microvascular Research)
Source: Microvascular Research - June 25, 2020 Category: Biochemistry Source Type: research

Minimizing the duration of laser Doppler flowmetry recordings while maintaining wavelet analysis quality: A methodological study
Publication date: Available online 23 June 2020Source: Microvascular ResearchAuthor(s): C. Reynès, A. Vinet, O. Maltinti, Y. Knapp (Source: Microvascular Research)
Source: Microvascular Research - June 24, 2020 Category: Biochemistry Source Type: research

Expression of miR-210 in the peripheral blood of patients with newly diagnosed type 2 diabetes mellitus and its effect on the number and function of endothelial progenitor cells
Publication date: Available online 10 June 2020Source: Microvascular ResearchAuthor(s): Xueting Li, Zeguo Jia, Xiaotong Zhao, Murong Xu, Mingwei Chen (Source: Microvascular Research)
Source: Microvascular Research - June 11, 2020 Category: Biochemistry Source Type: research

Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype
Publication date: Available online 9 June 2020Source: Microvascular ResearchAuthor(s): Andrew P. Voigt, S. Scott Whitmore, Kelly Mulfaul, Kathleen R. Chirco, Joseph C. Giacalone, Miles J. Flamme-Wiese, Adam Stockman, Edwin M. Stone, Budd A. Tucker, Todd E. Scheetz, Robert F. Mullins (Source: Microvascular Research)
Source: Microvascular Research - June 10, 2020 Category: Biochemistry Source Type: research

Optimizing finger systolic blood pressure measurements with laser Doppler: Validation of the second phalanx site
Publication date: Available online 9 June 2020Source: Microvascular ResearchAuthor(s): Sophie Blaise, Joël Constans, Laure Pellegrini, Patricia Senet, Isabelle Lazareth, Jean-Luc Cracowski, Patrick Carpentier (Source: Microvascular Research)
Source: Microvascular Research - June 9, 2020 Category: Biochemistry Source Type: research

Sex-differences in cholinergic, nicotinic, and β-adrenergic cutaneous vasodilation: Roles of nitric oxide synthase, cyclooxygenase, and K+ channels
Publication date: Available online 9 June 2020Source: Microvascular ResearchAuthor(s): Naoto Fujii, Gregory W. McGarr, Reem Ghassa, Madison Schmidt, James J. McCormick, Takeshi Nishiyasu, Glen P. Kenny (Source: Microvascular Research)
Source: Microvascular Research - June 9, 2020 Category: Biochemistry Source Type: research

Importance of the evaluation of systemic microvascular flow and reactivity in critically ill patients with coronavirus disease 2019 — COVID-19
Publication date: Available online 9 June 2020Source: Microvascular ResearchAuthor(s): Eduardo Tibirica, Andrea De Lorenzo (Source: Microvascular Research)
Source: Microvascular Research - June 9, 2020 Category: Biochemistry Source Type: research

The applications of heparin in vascular tissue engineering
Publication date: Available online 5 June 2020Source: Microvascular ResearchAuthor(s): Saba Aslani, Mahboubeh Kabiri, Simzar HosseinZadeh, Hana Hanaee-Ahvaz, Elham Sadat Taherzadeh, Masoud Soleimani (Source: Microvascular Research)
Source: Microvascular Research - June 5, 2020 Category: Biochemistry Source Type: research

The use of the chick embryo CAM assay in the study of angiogenic activiy of biomaterials
Publication date: Available online 5 June 2020Source: Microvascular ResearchAuthor(s): Domenico Ribatti, Tiziana Annese, Roberto Tamma (Source: Microvascular Research)
Source: Microvascular Research - June 5, 2020 Category: Biochemistry Source Type: research

Evaluation of microcirculation by Sidestream Dark Field imaging: Impact of hemodynamic status on the occurrence of pressure artifacts – A pilot study
Publication date: Available online 1 June 2020Source: Microvascular ResearchAuthor(s): Mathieu Magnin, Élisa Foulon, Thibaut Lurier, Bernard Allaouchiche, Jeanne Marie Bonnet Garin, Stéphane Junot (Source: Microvascular Research)
Source: Microvascular Research - June 2, 2020 Category: Biochemistry Source Type: research

Toxoplasma gondii infection impairs radial glia differentiation and its potential to modulate brain microvascular endothelial cell function in the cerebral cortex
Publication date: Available online 2 June 2020Source: Microvascular ResearchAuthor(s): Anne Caroline Marcos, Michele Siqueira, Liandra Alvarez-Rosa, Cynthia M. Cascabulho, Mariana C. Waghabi, Helene S. Barbosa, Daniel Adesse, Joice Stipursky (Source: Microvascular Research)
Source: Microvascular Research - June 2, 2020 Category: Biochemistry Source Type: research

Cardiovascular diseases and metabolic abnormalities associated with obesity: What is the role of inflammatory responses? A systematic review
Publication date: Available online 30 May 2020Source: Microvascular ResearchAuthor(s): Nadia Hamjane, Fatiha Benyahya, Naima Ghailani Nourouti, Mohcine Bennani Mechita, Amina Barakat (Source: Microvascular Research)
Source: Microvascular Research - May 31, 2020 Category: Biochemistry Source Type: research

Editorial Board
Publication date: July 2020Source: Microvascular Research, Volume 130Author(s): (Source: Microvascular Research)
Source: Microvascular Research - May 27, 2020 Category: Biochemistry Source Type: research

Implant-induced inflammatory angiogenesis is up-regulated in obese mice
Publication date: Available online 22 May 2020Source: Microvascular ResearchAuthor(s): Laura Alejandra Ariza Orellano, Simone Aparecida de Almeida, Luciana Xavier Pereira, Clara Tolentino Machado, Celso Tarso Rodrigues Viana, Silvia Passos Andrade, Paula Peixoto Campos (Source: Microvascular Research)
Source: Microvascular Research - May 23, 2020 Category: Biochemistry Source Type: research

Activation of NADPH/ROS pathway contributes to angiogenesis through JNK signaling in brain endothelial cells
Publication date: Available online 16 May 2020Source: Microvascular ResearchAuthor(s): Zairan Wang, Jiping Yang, Jinchong Qi, Yonghui Jin, Liyan Tong (Source: Microvascular Research)
Source: Microvascular Research - May 18, 2020 Category: Biochemistry Source Type: research

Heat transfer analysis of blood perfusion in diabetic rats using a genetic algorithm
Publication date: Available online 16 May 2020Source: Microvascular ResearchAuthor(s): Yueping Wang, Lizhong Mu, Ying He, Yuanliang Tang, Chao Liu, Yunxia Lu, Lisheng Xu (Source: Microvascular Research)
Source: Microvascular Research - May 17, 2020 Category: Biochemistry Source Type: research

Segmenting nailfold capillaries using an improved U-net network
Publication date: Available online 1 May 2020Source: Microvascular ResearchAuthor(s): Shupeng Liu, Yuemei Li, Jingjing Zhou, Junwei Hu, Na Chen, Yana Shang, Zhenyi Chen, Taihao Li (Source: Microvascular Research)
Source: Microvascular Research - May 2, 2020 Category: Biochemistry Source Type: research

The role of glutathione and glutathione peroxidase in regulating cellular level of reactive oxygen and nitrogen species
Publication date: Available online 23 April 2020Source: Microvascular ResearchAuthor(s): Sheetal Panday, Raghav Talreja, Mahendra Kavdia (Source: Microvascular Research)
Source: Microvascular Research - April 25, 2020 Category: Biochemistry Source Type: research

Expression and regulation of tumor necrosis factor-α-induced protein-8-like 2 is associated with acute lung injury induced by myocardial ischemia reperfusion in diabetic rats
Publication date: Available online 22 April 2020Source: Microvascular ResearchAuthor(s): Qian Kong, Min Yuan, Tingqian Ming, Qing Fang, Xiaojing Wu, Xuemin Song (Source: Microvascular Research)
Source: Microvascular Research - April 23, 2020 Category: Biochemistry Source Type: research

Profiling the endothelial function using both peripheral artery tonometry (EndoPAT) and Laser Doppler Flowmetry (LD) - Complementary studies or waste of time?
Publication date: Available online 21 April 2020Source: Microvascular ResearchAuthor(s): Maciej Jakubowski, Aleksandra Turek-Jakubowska, Ewa Szahidewicz-Krupska, Karolina Gawrys, Jakub Gawrys, Adrian Doroszko (Source: Microvascular Research)
Source: Microvascular Research - April 23, 2020 Category: Biochemistry Source Type: research

State-of-the-art technologies provide new insights linking skin and blood vessel abnormalities in SSc-related disorders
Publication date: Available online 19 April 2020Source: Microvascular ResearchAuthor(s): Graham Dinsdale, Sarah Wilkinson, Jack Wilkinson, Tonia L. Moore, Joanne B. Manning, Michael Berks, Elizabeth Marjanovic, Mark Dickinson, Ariane L. Herrick, Andrea K. Murray (Source: Microvascular Research)
Source: Microvascular Research - April 20, 2020 Category: Biochemistry Source Type: research

Transport of nanoparticles in magnetic targeting: Comparison of magnetic, diffusive and convective forces and fluxes in the microvasculature, through vascular pores and across the interstitium
Publication date: Available online 17 April 2020Source: Microvascular ResearchAuthor(s): Lydia I. Kolitsi, Stergios G. Yiantsios (Source: Microvascular Research)
Source: Microvascular Research - April 17, 2020 Category: Biochemistry Source Type: research

Structure-function correlation of localized visual field defects and macular microvascular damage in primary open-angle glaucoma
Publication date: Available online 30 March 2020Source: Microvascular ResearchAuthor(s): Aizhu Tao, Yuanbo Liang, Juanjuan Chen, Haishuang Hu, Qiangjie Huang, Jingwei Zheng, Cong Ye, Fan Lu (Source: Microvascular Research)
Source: Microvascular Research - April 1, 2020 Category: Biochemistry Source Type: research

Near-infrared spectroscopy-derived muscle oxygen saturation during exercise recovery and flow-mediated dilation are impaired in HIV-infected patients
Publication date: Available online 28 March 2020Source: Microvascular ResearchAuthor(s): Mônica Volino-Souza, Gustavo Vieira de Oliveira, Elisa Barros-Santos, Vivian Pinheiro, Ana Paula Machado-Santos, Carlos A. Conte-Junior, Thiago Silveira Alvares (Source: Microvascular Research)
Source: Microvascular Research - March 29, 2020 Category: Biochemistry Source Type: research

CASIN and AMD3100 enhance endothelial cell proliferation, tube formation and sprouting
Publication date: Available online 19 March 2020Source: Microvascular ResearchAuthor(s): Batuhan Mert Kalkan, Sezer Akgol, Deniz Ak, Dogacan Yucel, Gulen Guney Esken, Fatih Kocabas (Source: Microvascular Research)
Source: Microvascular Research - March 20, 2020 Category: Biochemistry Source Type: research

Murine double minute-2 mediates exercise-induced angiogenesis in adipose tissue of diet-induced obese mice
Publication date: Available online 19 March 2020Source: Microvascular ResearchAuthor(s): Thomas Loustau, Eugénie Coudiere, Esma Karkeni, Jean-François Landrier, Bernard Jover, Catherine Riva (Source: Microvascular Research)
Source: Microvascular Research - March 19, 2020 Category: Biochemistry Source Type: research

A pilot study: Wavelet cross-correlation of cardiovascular oscillations under controlled respiration in humans
Publication date: Available online 17 March 2020Source: Microvascular ResearchAuthor(s): Arina Tankanag, Gennadii Krasnikov, Mizeva Irina (Source: Microvascular Research)
Source: Microvascular Research - March 18, 2020 Category: Biochemistry Source Type: research

Limb blood flow and muscle oxygenation responses during handgrip exercise above vs. below critical force
Publication date: Available online 18 March 2020Source: Microvascular ResearchAuthor(s): Shane M. Hammer, Andrew M. Alexander, Kaylin D. Didier, Lillie M. Huckaby, Thomas J. Barstow (Source: Microvascular Research)
Source: Microvascular Research - March 18, 2020 Category: Biochemistry Source Type: research

Assessment of oxygenation with polarized light spectroscopy enables new means for detecting vascular events in the skin
Publication date: Available online 16 March 2020Source: Microvascular ResearchAuthor(s): Max Bergkvist, Joakim Henricson, Sara Bergstrand, Tomas Strömberg, Erik Tesselaar, Simon Farnebo (Source: Microvascular Research)
Source: Microvascular Research - March 17, 2020 Category: Biochemistry Source Type: research

Editorial Board
Publication date: May 2020Source: Microvascular Research, Volume 129Author(s): (Source: Microvascular Research)
Source: Microvascular Research - March 17, 2020 Category: Biochemistry Source Type: research

Corrigendum to “Migration velocity of red blood cells in microchannels” [Microvasc. Res. 124 (2019) 30–36]
Publication date: Available online 3 March 2020Source: Microvascular ResearchAuthor(s): Sylvain Losserand, Gwennou Coupier, Thomas Podgorski (Source: Microvascular Research)
Source: Microvascular Research - March 4, 2020 Category: Biochemistry Source Type: research

Corrigendum to “Endocan is useful biomarker of survival and severity in sepsis” [Microvasc. Res. 93 (2014) 92–97]
Publication date: Available online 29 February 2020Source: Microvascular ResearchAuthor(s): Dunja M. Mihajlovic, Dajana F. Lendak, Biljana G. Draskovic, Snezana V. Brkic, Gorana P. Mitic, Aleksandra S. Novakov Mikic, Tatjana N. Cebovic (Source: Microvascular Research)
Source: Microvascular Research - February 29, 2020 Category: Biochemistry Source Type: research

Diclofenac sodium loaded PLGA nanoparticles for inflammatory diseases with high anti-inflammatory properties at low dose: Formulation, characterization and in vivo HET-CAM analysis
Publication date: Available online 24 February 2020Source: Microvascular ResearchAuthor(s): A. Alper Öztürk, İrem Namlı, Kadri Güleç, H. Tuba Kıyan (Source: Microvascular Research)
Source: Microvascular Research - February 25, 2020 Category: Biochemistry Source Type: research

Three-dimensional visualization of coronary microvasculature in rats with myocardial infarction
ConclusionThree-dimensional visualization of opened coronary microvascular vessels is feasible in DiI-labelled myocardium in this rat MI model. This novel technique might be useful for defining the underlying mechanisms of coronary microvascular diseases and observe the efficacy of various therapy strategies on coronary microvessels. (Source: Microvascular Research)
Source: Microvascular Research - February 21, 2020 Category: Biochemistry Source Type: research

Resveratrol prevented experimental pulmonary vascular remodeling via miR-638 regulating NR4A3/cyclin D1 pathway
ConclusionOur data indicated that resveratrol prevented MCT-induced pulmonary vascular remodeling via miR-638 regulating NR4A3/cyclin D1 pathway. (Source: Microvascular Research)
Source: Microvascular Research - February 10, 2020 Category: Biochemistry Source Type: research

The role of circulating soluble fms-like tyrosine kinase-1 in patients with diabetic foot ulcer: A possible mechanism of pathogenesis via a novel link between oxidative stress, inflammation and angiogenesis
ConclusionThis study revealed that sFlt-1 is a major player in DFU pathogenesis and may be considered as a novel diagnostic biomarker for early detection of DFU. (Source: Microvascular Research)
Source: Microvascular Research - February 8, 2020 Category: Biochemistry Source Type: research

Fibulin-7 C-terminal fragment and its active synthetic peptide suppress choroidal and retinal neovascularization
Publication date: Available online 1 February 2020Source: Microvascular ResearchAuthor(s): Tomoko Ikeuchi, Yogita Kanan, Da Long, Susana de Vega, Kentaro Hozumi, Motoyoshi Nomizu, Peter A. Campochiaro, Yoshihiko YamadaAbstractWet age-related macular degeneration (AMD) and diabetic retinopathy are the leading causes of blindness through increased angiogenesis. Although VEGF-neutralizing proteins provide benefit, inconsistent responses indicate a need for new therapies. We previously identified the Fibulin-7 C-terminal fragment (Fbln7-C) as an angiogenesis inhibitor in vitro. Here we show that Fbln7-C inhibits neovasculariza...
Source: Microvascular Research - February 2, 2020 Category: Biochemistry Source Type: research

Utility of discovery approach using proteomics to create a biomarker profile for coronary microvascular dysfunction
Publication date: Available online 30 January 2020Source: Microvascular ResearchAuthor(s): Armin Nowroozpoor, David Gutterman, Basmah SafdarAbstractIntroductionCoronary microvascular dysfunction (CMD) is a complex disease, difficult to diagnose and often requires advanced imaging. We used mass spectrometry (MS) using discovery approach to search for serum proteins as potential biomarkers in these patients.MethodsWe used serum samples from 10 patients with CMD and 10 with normal coronary flow reserve (CFR) admitted to an observation unit where acute myocardial infarction was excluded. We identified CMD using 82Rb positron e...
Source: Microvascular Research - January 30, 2020 Category: Biochemistry Source Type: research

Association between impaired cutaneous microvascular endothelial function and lectin-like oxidized low-density lipoprotein receptor-1 in patients with coronary slow flow
This study was designed to test the hypothesis that the cutaneous microvascular endothelial function of CSF patients is impaired and correlates with lectin-like oxidized low-density lipoprotein receptor-1(LOX-1).Methods39 patients with CSF and 45 controls with normal coronary flow were enrolled. Velocity of coronary flow was quantitatively identified by thrombolysis in myocardial infarction frame count (TFC) method. LSCI system was used to assess subjects' cutaneous blood flow at rest and during PORH. Serum soluble LOX-1(sLOX-1) level was measured in all study subjects.ResultsPORH-induced vasodilation was significantly red...
Source: Microvascular Research - January 17, 2020 Category: Biochemistry Source Type: research

Angiogenic circular RNAs: A new landscape in cardiovascular diseases
Publication date: Available online 14 January 2020Source: Microvascular ResearchAuthor(s): Tian-Rong Zhang, Wei-Qiang HuangAbstractAngiogenesis refers to the formation of new blood vessels from existing blood vessels, including endothelial progenitor cells differentiation and cytokine regulation. Circular RNAs, a type of non-coding RNA, are a stable and conservative endogenous transcriptional product with a circular structure that is produced by the reverse and scrambled splicing of mRNA precursors. They can be used as microRNA sponges, are involved in transcription and protein translation, and regulate the pathophysiologi...
Source: Microvascular Research - January 15, 2020 Category: Biochemistry Source Type: research

Editorial Board
Publication date: March 2020Source: Microvascular Research, Volume 128Author(s): (Source: Microvascular Research)
Source: Microvascular Research - January 15, 2020 Category: Biochemistry Source Type: research

Activating α7nAChRs enhances endothelial progenitor cell function partially through the JAK2/STAT3 signaling pathway
This study reveals that α7nAChRs are potential therapeutic targets for angiogenesis and that the JAK2/STAT3 pathway plays a vital role in the associated therapeutic mechanism. (Source: Microvascular Research)
Source: Microvascular Research - January 9, 2020 Category: Biochemistry Source Type: research

Aortic stiffness is not only associated with structural but also functional parameters of retinal microcirculation
Publication date: Available online 7 January 2020Source: Microvascular ResearchAuthor(s): Edyta Dąbrowska, Joanna M. Harazny, Eliza Miszkowska-Nagórna, Adrian Stefański, Beata Graff, Katarzyna Kunicka, Ewa Świerblewska, Agnieszka Rojek, Anna Szyndler, Dariusz Gąsecki, Jacek Wolf, Marcin Gruchała, Stephane Laurent, Roland E. Schmieder, Krzysztof NarkiewiczAbstractObjectiveThe aim of the study was to test the hypothesis that alterations in large arteries are associated with microvascular remodelling and decreased retinal capillary blood flow.MethodsThe study group comprised of 88 patients with essential hypertens...
Source: Microvascular Research - January 7, 2020 Category: Biochemistry Source Type: research

Sublingual microvasculature in diabetic patients
Publication date: Available online 30 December 2019Source: Microvascular ResearchAuthor(s): Patricia P. Wadowski, Alexandra Kautzky-Willer, Thomas Gremmel, Renate Koppensteiner, Peter Wolf, Sebastian Ertl, Constantin Weikert, Christian Schörgenhofer, Bernd JilmaAbstractDiabetes is associated with micro- and macrovascular complications. The aim of the study was to investigate microvascular parameters (glycocalyx dimensions, perfused and total capillary density) in vivo in patients with type 1 and type 2 diabetes mellitus.In vivo sublingual videomicroscopy using sidestream darkfield - derived imaging was performed in 36...
Source: Microvascular Research - December 30, 2019 Category: Biochemistry Source Type: research

Up-regulation of brain cytokines and metalloproteinases 1 and 2 contributes to neurological deficit and brain damage in transient ischemic stroke
Publication date: Available online 28 December 2019Source: Microvascular ResearchAuthor(s): Edna Constanza Gómez Victoria, Eliana Cristina de Brito Toscano, Fabrício Marcus Silva Oliveira, Bárbara Andrade de Carvalho, Marcelo Vidigal Caliari, Antônio Lúcio Teixeira, Aline Silva de Miranda, Milene Alvarenga RachidAbstractIschemic stroke represents a major cause of adult death and severe neurological disability worldwide. Reperfusion following brain ischemia produces an inflammatory cascade that increases brain damage. In this context, matrix metalloproteinases (MMPs) play an important role ...
Source: Microvascular Research - December 30, 2019 Category: Biochemistry Source Type: research

Nailfold capillaroscopic changes in patients with chronic viral hepatitis
In this study, we investigated possible dermoscopic differences in the vascular appearance of the nailfold capillaries and their association with the disease's clinical status.MethodA hundred and forty-seven patients and 147 healthy controls were enrolled in this study. The patients' group consisted of chronic viral hepatitis B (CHB: 54 cases), chronic hepatitis C (CHC: 36 cases) and carrier of hepatitis B virus infection (CRHB: 57 cases). Nailfold capillaroscopy was performed using a digital dermoscope (Molemax II, X30). All capillaroscopy images were evaluated for capillary density, capillary loop enlargement, capillary ...
Source: Microvascular Research - December 30, 2019 Category: Biochemistry Source Type: research