An inverse association between tea consumption and colorectal cancer risk.
Authors: Chen Y, Wu Y, Du M, Chu H, Zhu L, Tong N, Zhang Z, Wang M, Gu D, Chen J Abstract It is well known that the tea extracts, mainly polyphenols as chemo-preventive elements, could act as cancer progression blockers. Although the association between tea consumption and colorectal cancer risk has been widely investigated, the results still remain inconsistent. We conducted a dose-response meta-analysis to evaluate their relationships by enrolling qualified 29 literatures. The summary odds ratio (OR) of colorectal cancer for the highest vs. lowest tea consumption was 0.93 with 0.87-1.00 of 95% confidence...
Source: Oncotarget - April 30, 2017 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Abstract B14: Modulating effects of green and black tea on biomarkers of chronic inflammation by gender and smoking status
Conclusion: This data implies that smokers are more likely to benefit from green tea intake while the beneficial effects of black tea are observed among former smokers.Note: This abstract was not presented at the conference.Citation Format: Iman A. Hakim, Sami A. Aldaham, Janet Foote, H-H Sherry Chow. Modulating effects of green and black tea on biomarkers of chronic inflammation by gender and smoking status. [abstract]. In: Proceedings of the AACR Special Conference: Improving Cancer Risk Prediction for Prevention and Early Detection; Nov 16-19, 2016; Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev ...
Source: Cancer Epidemiology Biomarkers and Prevention - April 30, 2017 Category: Cancer & Oncology Authors: Hakim, I. A., Aldaham, S. A., Foote, J., Chow, H.-H. S. Tags: Improving Cancer Risk Prediction for Prevention and Early Detection: Poster Presentations - Proffered Abstracts Source Type: research

Dietary tea polyphenols ameliorate metabolic syndrome and memory impairment via circadian clock related mechanisms
Conclusion Tea polyphenols supplementation might serve as future strategies to combat obesity, metabolic syndrome and cognitive disorder induced by circadian dysfunction. (Source: Journal of Functional Foods)
Source: Journal of Functional Foods - April 29, 2017 Category: Nutrition Source Type: research

Metabolic phenotyping of various tea (Camellia sinensis L.) cultivars and understanding of their intrinsic metabolism
Publication date: 15 October 2017 Source:Food Chemistry, Volume 233 Author(s): Hyang-Gi Ji, Yeong-Ran Lee, Min-Seuk Lee, Kyeng Hwan Hwang, Eun-Hee Kim, Jun Seong Park, Young-Shick Hong Recently, we selected three tea (Camellia sinensis) cultivars that are rich in taste, epigallocatechin-3-O-gallate (EGCG) and epigallocatechin-3-O-(3-O-methyl)-gallate (EGCG3″Me) and then cultivated them through asexual propagation by cutting in the same region. In the present study, proton nuclear magnetic resonance (1H NMR)-based metabolomics was applied to characterize the metabotype and to understand the metabolic mechanism of...
Source: Food Chemistry - April 29, 2017 Category: Food Science Source Type: research

Fatty acid and sterol composition of tea seed oils: Their comparison by the “FancyTiles” approach
Publication date: 15 October 2017 Source:Food Chemistry, Volume 233 Author(s): Xiaoqin Wang, Qiumei Zeng, Vito Verardo, María del Mar Contreras Confusion among tea seed oils from Sect. Thea, Oleifera and Camellia in Camellia is a widespread problem in research and production. In this work, 22 fatty acids, squalene and 13 phytosterols in the three groups of tea seed oils from 16 Chinese regions were analyzed with GC-FID and GC-MS respectively. Thea oils were significantly higher in linoleic (C18:2) and palmitic (C16:0) acids but lower in oleic acid (C18:1) than Camellia and Oleifera oils while the latter two overlapp...
Source: Food Chemistry - April 29, 2017 Category: Food Science Source Type: research

Tea consumption and the risk of ovarian cancer: A meta-analysis of epidemiological studies.
In conclusion, our meta-analysis showed an inverse association between tea consumption and ovarian cancer risk. High quality cohort-clinical trials should be conducted on different tea types and their relationship with ovarian cancer. PMID: 28445129 [PubMed - as supplied by publisher] (Source: Oncotarget)
Source: Oncotarget - April 27, 2017 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Tea consumption and risk of ischaemic heart disease
Conclusions In this large prospective study, daily tea consumption was associated with a reduced risk of IHD. (Source: Heart)
Source: Heart - April 26, 2017 Category: Cardiology Authors: Li, X., Yu, C., Guo, Y., Bian, Z., Si, J., Yang, L., Chen, Y., Ren, X., Jiang, G., Chen, J., Chen, Z., Lv, J., Li, L., on behalf of the China Kadoorie Biobank Collaborative Group Tags: Open access Cardiac risk factors and prevention Source Type: research

Nanotechnological approaches to enhance the bioavailability and therapeutic efficacy of green tea polyphenols
Publication date: July 2017 Source:Journal of Functional Foods, Volume 34 Author(s): Pradeep Puligundla, Chulkyoon Mok, Sanghoon Ko, Jin Liang, Neeraja Recharla Green tea contains numerous bioactive compounds that may provide multiple health benefits, including antioxidative, anti-inflammatory, anti-carcinogenic, anti-proliferative, anti-hypertensive, antithrombogenic and lipid-lowering effects. Most of the chemopreventive and therapeutic effects of green tea extracts have been attributed to the presence of different polyphenolic bioactives, especially catechins, in their composition. Although these polyphenolic com...
Source: Journal of Functional Foods - April 26, 2017 Category: Nutrition Source Type: research

Tea phytochemicals for breast cancer prevention and intervention: From bench to bedside and beyond
Publication date: Available online 7 April 2017 Source:Seminars in Cancer Biology Author(s): Dona Sinha, Jaydip Biswas, Seyed Mohammad Nabavi, Anupam Bishayee The National Cancer Institute of the United States had projected breast cancer as one of the topmost prevalent malignancies of 2016. It was estimated that in 2016, 246,660 new cases of invasive breast cancer were expected to be diagnosed in women in the US, along with 61,000 new cases of non-invasive (in situ) breast cancer. The heterogeneity of breast cancer accounts for its differential molecular subtyping. Recent incorporation of high throughput approaches h...
Source: Seminars in Cancer Biology - April 23, 2017 Category: Cancer & Oncology Source Type: research

Appropriately raising fermentation temperature beneficial to the increase of antioxidant activity and gallic acid content in Eurotium cristatum-fermented loose tea
In this study, gallic acid contents and antioxidant properties of Eurotium cristatum-fermented loose tea at different fermentation temperatures were analyzed. The results showed that E. cristatum fermentation had resulted in an obvious increase of the antioxidant ability, and fermentation temperature significantly affected gallic acid and antioxidant ability of E. cristatum-fermented loose tea (p < 0.05). Appropriately raising fermentation temperature significantly contributes to increasing gallic acid content and antioxidant ability of E. cristatum-fermented loose tea (p < 0.05). Gallic acid was significa...
Source: LWT Food Science and Technology - April 23, 2017 Category: Food Science Source Type: research

Theanine: the unique amino acid in the tea plant as an oral hepatoprotective agent.
Abstract For thousands of years, humans have consumed tea made from leaves of Camellia sinensis, first as a medicinal herb and then as a widely popular beverage. In the past 10 years, theanine, a tea-derived, unique, nonproteinic amino acid, has been extensively studied for its health benefits. Recently, multiple lines of evidence have proven its beneficial effects on hepatic and immune functions. One possible mechanism for its biological activity involves the downregulation of the inflammatory response through the induction of nitric oxide production and glutathione synthesis. In this review, we summarize...
Source: Asia Pacific Journal of Clinical Nutrition - April 22, 2017 Category: Nutrition Authors: Wang D, Gao Q, Wang T, Qian F, Wang Y Tags: Asia Pac J Clin Nutr Source Type: research

Effect modification of green tea on the association between rice intake and the risk of diabetes mellitus: a prospective study in Japanese men and women.
CONCLUSIONS: Rice intake was associated with an increased risk of diabetes only in women, and women with a higher intake of green tea had a lower risk of diabetes. A high intake of green tea may be protective against increased risk of diabetes with a higher intake of rice in women. PMID: 28429922 [PubMed - in process] (Source: Asia Pacific Journal of Clinical Nutrition)
Source: Asia Pacific Journal of Clinical Nutrition - April 22, 2017 Category: Nutrition Authors: Hirata A, Ohnaka K, Tashiro N, Wang Z, Kohno M, Kiyohara C, Kono S, Takayanagi R Tags: Asia Pac J Clin Nutr Source Type: research

Physiologically based pharmacokinetic modeling of tea catechin mixture in rats and humans
The objectives of this study were to develop and validate a physiologically based pharmacokinetic (PBPK) model of tea catechin mixture (TCM) in rats and humans, and to predict an integrated or total concentration of TCM in the plasma of humans after consuming GT or Polyphenon E (PE). To this end, a PBPK model of epigallocatechin gallate (EGCg) consisting of 13 first‐order, blood flow‐limited tissue compartments was first developed in rats. The rat model was scaled up to humans by replacing its physiological parameters, pharmacokinetic parameters and tissue/blood partition coefficients (PCs) with human‐specific values...
Source: Pharmacology Research and Perspectives - April 17, 2017 Category: Drugs & Pharmacology Authors: Francis C. P. Law, Meicun Yao, Hui ‐Chang Bi, Stephen Lam Tags: Original Article Source Type: research

Analysis of honeybush tea (Cyclopia spp.) volatiles by comprehensive two-dimensional gas chromatography using a single-stage thermal modulator.
Abstract The applicability of comprehensive two-dimensional gas chromatography (GC×GC) using a single-stage thermal modulator was explored for the analysis of honeybush tea (Cyclopia spp.) volatile compounds. Headspace solid phase micro-extraction (HS-SPME) was used in combination with GC×GC separation on a non-polar × polar column set with flame ionisation (FID) detection for the analysis of fermented Cyclopia maculata, Cyclopia subternata and Cyclopia genistoides tea infusions of a single harvest season. Method optimisation entailed evaluation of the effects of several experimental parameters on the p...
Source: Analytical and Bioanalytical Chemistry - April 17, 2017 Category: Chemistry Authors: Ntlhokwe G, Tredoux AGJ, Górecki T, Edwards M, Vestner J, Muller M, Erasmus L, Joubert E, Christel Cronje J, de Villiers A Tags: Anal Bioanal Chem Source Type: research

Optimization and validation of Folin-Ciocalteu method for the determination of total polyphenol content of Pu-erh tea.
Authors: Musci M, Yao S Abstract Pu-erh tea is a post-fermented tea that has recently gained popularity worldwide, due to potential health benefits related to the antioxidant activity resulting from its high polyphenolic content. The Folin-Ciocalteu method is a simple, rapid, and inexpensive assay widely applied for the determination of total polyphenol content. Over the past years, it has been subjected to many modifications, often without any systematic optimization or validation. In our study, we sought to optimize the Folin-Ciocalteu method, evaluate quality parameters including linearity, precision an...
Source: International Journal of Food Sciences and Nutrition - April 14, 2017 Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research