Theagalloflavic Acid, a New Pigment Derived from Hexahydroxydiphenoyl Group, and Lignan Oxidation Products Produced by Aerobic Microbial Fermentation of Green Tea.
Abstract Chinese ripe pu-erh tea is produced by aerobic microbial fermentation of green tea. To clarify the microbial degradation of tea polyphenols, Japanese commercial green tea was mixed with Chinese ripe pu-erh tea, which retains microorganisms, and fermented for 5 d. Chromatographic separation yielded a novel water-soluble yellow pigment termed theagalloflavic acid. Spectroscopic and chemical evidence suggested that this pigment was produced by oxidative ring cleavage of hexahydroxydiphenoyl esters. In addition, two new oxygenated lignin metabolites, (+)-5,5'-dihydroxypinoresinol and 5-hydroxydihydr...
Source: Chemical and Pharmaceutical Bulletin - July 7, 2016 Category: Drugs & Pharmacology Authors: Matsuo Y, Matsuda T, Sugihara K, Saito Y, Zhang YJ, Yang CR, Tanaka T Tags: Chem Pharm Bull (Tokyo) Source Type: research

Coffee, tea and caffeine intake and the risk of non-melanoma skin cancer: a review of the literature and meta-analysis
Conclusions Coffee intake appears to exert a moderate protective effect against BCC development, probably through the biological effect of caffeine. However, the observational nature of studies included, subject to bias and confounding, suggests taking with caution these results that should be verified in randomized clinical trials. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - July 6, 2016 Category: Nutrition Source Type: research

TBC2health: a database of experimentally validated health-beneficial effects of tea bioactive compounds.
Abstract Tea is one of the most consumed beverages in the world. Considerable studies show the exceptional health benefits (e.g. antioxidation, cancer prevention) of tea owing to its various bioactive components. However, data from these extensively published papers had not been made available in a central database. To lay a foundation in improving the understanding of healthy tea functions, we established a TBC2health database that currently documents 1338 relationships between 497 tea bioactive compounds and 206 diseases (or phenotypes) manually culled from over 300 published articles. Each entry in TBC2...
Source: Briefings in Bioinformatics - July 5, 2016 Category: Bioinformatics Authors: Zhang S, Xuan H, Zhang L, Fu S, Wang Y, Yang H, Tai Y, Song Y, Zhang J, Ho CT, Li S, Wan X Tags: Brief Bioinform Source Type: research

Variations of rhizosphere bacterial communities in tea (Camellia sinensis L.) continuous cropping soil by high‐throughput pyrosequencing approach
ConclusionLong‐term tea cultivation altered the composition and structure of soil bacterial community, which led to the reduction of the beneficial bacteria. Significance and Impact of the StudyThe results can provide clues on how to regulate the soil microbial community and maintain the health of soils in tea orchard systems.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)
Source: Journal of Applied Microbiology - July 4, 2016 Category: Microbiology Authors: Yanchun Li, Zhou Li, Zhaowei Li, Yuhang Jiang, Boqi Weng, Wenxiong Lin Tags: Original Article Source Type: research

Polymeric black tea polyphenols (PBPs) inhibit benzo(a)pyrene and 4 ‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone induced lung carcinogenesis potentially through down‐regulation of p38 and Akt phosphorylation in A/J mice
ConclusionsPBPs, most abundant polyphenolic component in the black tea, have chemopreventive effect through inhibition of inflammation, cellular proliferation and induction of apoptosis possibly via modulation of signaling kinases. This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - July 4, 2016 Category: Molecular Biology Authors: Rasika R Hudlikar, V. Venkadakrishnan, Rajiv Kumar Kaushal, Rahul A. Thorat, Sadhana Kannan, Arvind D. Ingle, Saral Desai, Girish B. Maru, Manoj B. Mahimkar Tags: Research Article Source Type: research

Polymeric black tea polyphenols (PBPs) inhibit benzo(a)pyrene and 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone induced lung carcinogenesis potentially through down‐regulation of p38 and Akt phosphorylation in A/J mice
ConclusionsPBPs, most abundant polyphenolic component in the black tea, have chemopreventive effect through inhibition of inflammation, cellular proliferation and induction of apoptosis possibly via modulation of signaling kinases. This article is protected by copyright. All rights reserved (Source: Molecular Carcinogenesis)
Source: Molecular Carcinogenesis - July 4, 2016 Category: Molecular Biology Authors: Rasika R Hudlikar, V. Venkadakrishnan, Rajiv Kumar Kaushal, Rahul A. Thorat, Sadhana Kannan, Arvind D. Ingle, Saral Desai, Girish B. Maru, Manoj B. Mahimkar Tags: Research Article Source Type: research

Effect of green tea extract on bonding durability of an etch-and-rinse adhesive system to caries-affected dentin
Conclusion It was concluded that the application of 2% green tea extract was able to increase bond durability of the etch-and-rinse system to dentin. Neither the application of chlorhexidine nor non-treatment (NT - control) had any effect on bond strength after water storage. (Source: Journal of Applied Oral Science)
Source: Journal of Applied Oral Science - July 4, 2016 Category: Dentistry Source Type: research

Rapid assessment of black tea quality using diffuse reflectance spectroscopy
In this study¸ we examined the DRS approach by creating a reflectance spectral imaging of 81 black crush, tear and curl (CTC) tea samples and eight tea quality parameters. Spectral models for each parameter were developed using the partial-least-squares regression (PLSR) approach. The ratio of performance deviation (RPD) was used to assess such spectral models. Results showed that moisture content, thearubigin components of TRSI and TRSII, total polyphenol contents and liquor brightness were accurately predicted with RPD values 3.63, 2.32, 2.24, 2.23 and 2.02, respectively. Prediction accuracies were moderate for thearubi...
Source: Journal of Food Engineering - July 3, 2016 Category: Food Science Source Type: research

Mate and Tea Intake, Dietary Antioxidants and Risk of Breast Cancer: a Case-Control Study.
In conclusion, a strong and inverse association for 'mate' intake and BC was found, independent of dietary antioxidant levels. Also strong inverse associations with tea intake were more evident only at high levels of certain dietary antioxidants. PMID: 27356713 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - July 2, 2016 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Association of green tea consumption with mortality from all-cause, cardiovascular disease and cancer in a Chinese cohort of 165,000 adult men
Abstract Tea is the most ancient and popular beverage in the world, and its beneficial health effects has attracted tremendous attention worldwide. However, the prospective evidence relating green tea consumption to total and cause-specific mortality is still limited and inconclusive. We recruited 164,681 male participants free of pre-existing disease during 1990–1991, with green tea consumption and other covariates assessed by the standardized questionnaire and mortality follow up continued until 2006 (mean 11 years; total person-years: 1,961,791). Cox regression analyses were used to quantify the ass...
Source: European Journal of Epidemiology - July 1, 2016 Category: Epidemiology Source Type: research

Prolonged Feeding with Green Tea Polyphenols Exacerbates Cholesterol‐induced Fatty Liver Disease in Mice
ConclusionProlonged GTE supplementation dramatically increased hepatic oxidative stress, inflammation and liver injury, and altered the bile acid synthesis pathway in mice fed a HCD.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 30, 2016 Category: Food Science Authors: Nina Hirsch, Anya Konstantinov, Sarit Anavi, Anna Aronis, Zion Hagay, Zecharia Madar, Oren Tirosh Tags: Research Article Source Type: research

Prolonged Feeding with Green Tea Polyphenols Exacerbates Cholesterol ‐induced Fatty Liver Disease in Mice
ConclusionProlonged GTE supplementation dramatically increased hepatic oxidative stress, inflammation and liver injury, and altered the bile acid synthesis pathway in mice fed a HCD.This article is protected by copyright. All rights reserved (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - June 30, 2016 Category: Food Science Authors: Nina Hirsch, Anya Konstantinov, Sarit Anavi, Anna Aronis, Zion Hagay, Zecharia Madar, Oren Tirosh Tags: Research Article Source Type: research

Green Tea Polyphenols Alleviate Autophagy Inhibition Induced by High Glucose in Endothelial Cells.
Abstract Bovine aortic endothelial cells (BAECs) were cultured with high glucose (33 mmol/L), 4 mg/L green tea polyphenols (GTPs) or 4 mg/L GTPs co-treatment with high glucose for 24 h in the presence or absence of Bafilomycin-A1 (BAF). We observed that high glucose increased the accumulation of LC3-II. Treatment with BAF did not further increase the accumulation of LC3-II. Results also showed an increased level of p62 and decreased Beclin-1. However, GTPs showed inversed trends of those proteins. Furthermore, GTPs co-treatment with high glucose decreased the level of LC3-II and a much higher accumulation ...
Source: Biomedical and Environmental Sciences : BES - June 30, 2016 Category: Biomedical Science Authors: Zhang PW, Tian C, Xu FY, Chen Z, Burnside R, Yi WJ, Xiang SY, Xie X, Wu NN, Yang H, Zhao NN, Ye XL, Ying CJ Tags: Biomed Environ Sci Source Type: research

Alteration in bone geometric and mechanical properties, histomorphometrical parameters of trabecular bone, articular cartilage, and growth plate in adolescent rats after chronic co-exposure to cadmium and lead in the case of supplementation with green, black, red and white tea
Publication date: Available online 29 June 2016 Source:Environmental Toxicology and Pharmacology Author(s): Ewa Tomaszewska, Piotr Dobrowolski, Anna Winiarska-Mieczan, Małgorzata Kwiecień, Agnieszka Tomczyk, Siemowit Muszyński, Radosław Radzki Adolescent male Wistar rats were used to check whether regular consumption of black, red, white, or green tea would have a protective effect on femur development during 12-week exposure to Cd and Pb (7mg Cd and 50mg Pb in 1kg of the diet). The animals were randomly divided (n=12) into a positive control (without Cd, Pb and teas), a negative control group (Cd and...
Source: Environmental Toxicology and Pharmacology - June 29, 2016 Category: Environmental Health Source Type: research

Gene expression analysis of bud and leaf color in tea
Publication date: October 2016 Source:Plant Physiology and Biochemistry, Volume 107 Author(s): Kang Wei, Yazhen Zhang, Liyun Wu, Hailin Li, Li Ruan, Peixian Bai, Chengcai Zhang, Fen Zhang, Liyi Xu, Liyuan Wang, Hao Cheng Purple shoot tea attributing to the high anthocyanin accumulation is of great interest for its wide health benefits. To better understand potential mechanisms involved in purple buds and leaves formation in tea plants, we performed transcriptome analysis of six green or purple shoot tea individuals from a F1 population using the Illumina sequencing method. Totally 292 million RNA-...
Source: Plant Physiology and Biochemistry - June 28, 2016 Category: Biochemistry Source Type: research