Antifungal activities of fluoroindoles against the postharvest pathogen Botrytis cinerea: In vitro and in silico approaches
Int J Food Microbiol. 2021 Nov 24;362:109492. doi: 10.1016/j.ijfoodmicro.2021.109492. Online ahead of print.ABSTRACTBotrytis cinerea is a common necrotrophic fungal pathogen, leading cause of gray mold diseases in plants and fruit. Several benzimidazoles are used for controlling B. cinerea-associated infection in fruit and vegetables, but benzimidazoles resistance restricts its further uses. Therefore, it is a need for alternative drugs that control B. cinerea. Indoles are multi-faceted compounds and their structural similarities with antifungal benzimidazoles make them a choice for further investigation. Thus, the main ob...
Source: International Journal of Food Microbiology - December 3, 2021 Category: Food Science Authors: Chaitany Jayprakash Raorane Vinit Raj Jin-Hyung Lee Jintae Lee Source Type: research
< em > Citrus < /em > Genus and Its Waste Utilization: A Review on Health-Promoting Activities and Industrial Application
Evid Based Complement Alternat Med. 2021 Oct 20;2021:2488804. doi: 10.1155/2021/2488804. eCollection 2021.ABSTRACTCitrus fruits such as oranges, grapefruits, lemons, limes, tangerines, and mandarins, whose production is increasing every year with the rise of consumer demand, are among the most popular fruits cultivated throughout the globe. Citrus genus belongs to the Rutaceae family and is known for its beneficial effects on health for centuries. These plant groups contain many beneficial nutrients and bioactive compounds. These compounds have antimicrobial, anticancer, antidiabetic, antiplatelet aggregation, and anti-inf...
Source: Evidence-based Complementary and Alternative Medicine - November 19, 2021 Category: Complementary Medicine Authors: Usman Mir Khan Aysha Sameen Rana Muhammad Aadil Muhammad Shahid Serap Sezen Ali Zarrabi Betul Ozdemir Mustafa Sevindik Dilara Nur Kaplan Zeliha Selamoglu Alibek Ydyrys T Anitha Manoj Kumar Javad Sharifi-Rad Monica Butnariu Source Type: research
Based on Activation of p62-Keap1-Nrf2 Pathway, Hesperidin Protects Arsenic-Trioxide-Induced Cardiotoxicity in Mice
Conclusions: The results demonstrate that HES protects against ATO-induced cardiotoxicity, through inhibiting oxidative stress, and subsequent inflammation and apoptosis. The underlying results are closely related to the regulation of the p62-Keap1-Nrf2 signalling pathway. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - October 13, 2021 Category: Drugs & Pharmacology Source Type: research
Mixed polysaccharides derived from shiitake mushroom, Poriacocos, Ginger and Tangerine peel prevent the H1N1 virus infections in mice
Biosci Biotechnol Biochem. 2021 Oct 8:zbab174. doi: 10.1093/bbb/zbab174. Online ahead of print.ABSTRACTThe pandemic influenza A (H1N1) virus spread globally and posed one of the most serious global public health challenges. The traditional Chinese medicine is served as a complementary treatment strategy with vaccine immunization. Here, we demonstrated the mixed polysaccharides (MPs) derived from shiitake mushroom, poriacocos, ginger and tyangerine peel prevent the H1N1 virus infections in mice. MPs pretreatment attenuated H1N1 virus-induced weight loss, clinical symptoms and death. The lymphocytes detection results showed ...
Source: Bioscience, Biotechnology, and Biochemistry - October 9, 2021 Category: Biochemistry Authors: Diqi Yang Minghua Hu Hongmei Zhu Jianguo Chen Dehai Wang Mingxing Ding Li Han Source Type: research
Mixed polysaccharides derived from shiitake mushroom, Poriacocos, Ginger and Tangerine peel prevent the H1N1 virus infections in mice
Biosci Biotechnol Biochem. 2021 Oct 8:zbab174. doi: 10.1093/bbb/zbab174. Online ahead of print.ABSTRACTThe pandemic influenza A (H1N1) virus spread globally and posed one of the most serious global public health challenges. The traditional Chinese medicine is served as a complementary treatment strategy with vaccine immunization. Here, we demonstrated the mixed polysaccharides (MPs) derived from shiitake mushroom, poriacocos, ginger and tyangerine peel prevent the H1N1 virus infections in mice. MPs pretreatment attenuated H1N1 virus-induced weight loss, clinical symptoms and death. The lymphocytes detection results showed ...
Source: Bioscience, Biotechnology, and Biochemistry - October 9, 2021 Category: Biochemistry Authors: Diqi Yang Minghua Hu Hongmei Zhu Jianguo Chen Dehai Wang Mingxing Ding Li Han Source Type: research
Mixed polysaccharides derived from shiitake mushroom, Poriacocos, Ginger and Tangerine peel prevent the H1N1 virus infections in mice
Biosci Biotechnol Biochem. 2021 Oct 8:zbab174. doi: 10.1093/bbb/zbab174. Online ahead of print.ABSTRACTThe pandemic influenza A (H1N1) virus spread globally and posed one of the most serious global public health challenges. The traditional Chinese medicine is served as a complementary treatment strategy with vaccine immunization. Here, we demonstrated the mixed polysaccharides (MPs) derived from shiitake mushroom, poriacocos, ginger and tyangerine peel prevent the H1N1 virus infections in mice. MPs pretreatment attenuated H1N1 virus-induced weight loss, clinical symptoms and death. The lymphocytes detection results showed ...
Source: Bioscience, Biotechnology, and Biochemistry - October 9, 2021 Category: Biochemistry Authors: Diqi Yang Minghua Hu Hongmei Zhu Jianguo Chen Dehai Wang Mingxing Ding Li Han Source Type: research
242 High potency activities of a Tangerine extract to target Rosaceae imprints
Rosacea, a chronic skin disorder, is characterized by inflammation and vascular abnormalities of the central facial skin. Cathelicidin LL-37 and VEGF are both specific contributors to physiopathology of Rosaceae and involved in inflammatory and angiogenesis pathways respectively. The aim of this work was to assess the soothing and anti-redness properties of a dermo-cosmetic ingredient in several models exposed to the different components of the rosacea environment. Firstly, the use of human normal keratinocyte primary cell line (NHEK) after a tangerine extract pre-treatment allowed us to show a decrease of VEGF and MMP9 ge...
Source: Journal of Investigative Dermatology - October 1, 2021 Category: Dermatology Authors: F. Lestienne, H. Hernandez-Pigeon, M. Galliano, H. Delga, S. Alvarez-Georges, K. Andr é, M. Aries, S. Bessou-Touya, H. Duplan Source Type: research
Acceptability and satisfaction towards self-collection for chlamydia and gonorrhoea testing among transgender women in Tangerine Clinic, Thailand: shifting towards the new normal
CONCLUSIONS: Thai transgender women had high acceptability and satisfaction towards self-collection for CT/NG testing. The performance was promising compared to provider collection. Our results support the implementation of self-collection to the sexually transmitted infection services, particularly during the COVID-19 pandemic where physical distancing is the new normal. A larger study is warranted to determine the performance of self-collection for CT/NG testing in each anatomical compartment and confirm the performance between self-collection and provider collection.PMID:34496152 | DOI:10.1002/jia2.25801 (Source: Journa...
Source: Journal of the International AIDS Society - September 8, 2021 Category: Infectious Diseases Authors: Akarin Hiransuthikul Rena Janamnuaysook Linrada Himma Chiraporn Taya Tidarat Amatsombat Phongdanai Chumnanwet Kritima Samitpol Artsanee Chancham Jiratchaya Kongkapan Jeeranuch Rueannak Pintusorn Getwongsa Peevara Srimanus Nipat Teeratakulpisarn Narukjapor Source Type: research
Neovaginal and Anal High-Risk Human Papillomavirus DNA Among Thai Transgender Women in Gender Health Clinics
Conclusions
One of 5 transgender women visiting sexual health clinics in Bangkok was found to have hrHPV DNA in neovaginal and anal compartments. Studies are needed to look at incidence and persistence of hrHPV infection to inform anogenital precancerous and cancerous screening programs for transgender women. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - July 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research
Molecules, Vol. 26, Pages 4202: Evaluation of the Health-Promoting Properties of Selected Fruits
In this study, the health-promoting benefits of different fruits grown in Madeira Island, namely lemon (Citrus limon var. eureka), tangerine (Citrus reticulata var. setubalense), pitanga (Eugenia uniflora var. red), tomato (Solanum lycopersicum var. gordal) and uva-da-serra, an endemic blueberry (Vaccinium padifolium Sm.), were investigated. The phenolic composition (total phenolics and total flavonoids content) and antioxidant capacity (assessed through ABTS and DPPH assays) were measured revealing a high phenolic potential for all fruits, except tomato, while uva-da-serra is particularly rich in flavonoids. In relation t...
Source: Molecules - July 10, 2021 Category: Chemistry Authors: Jos é A. Figueira Priscilla Porto-Figueira Cristina Berenguer Jorge A. M. Pereira Jos é S. Câmara Tags: Article Source Type: research
Tangerine tomatoes: origin, biochemistry, potential health benefits and future prospects
(Source: Critical Reviews in Food Science and Nutrition)
Source: Critical Reviews in Food Science and Nutrition - July 9, 2021 Category: Nutrition Authors: Tanambell, Hartono Bishop, Karen Suzanne Quek, Siew Young Source Type: research
Peroxisomes Implicated in the Biosynthesis of Siderophores and Biotin, Cell Wall Integrity, Autophagy, and Response to Hydrogen Peroxide in the Citrus Pathogenic Fungus Alternaria alternata
Little is known about the roles of peroxisomes in the necrotrophic fungal plant pathogens. In the present study, a Pex6 gene encoding an ATPase-associated protein was characterized by analysis of functional mutations in the tangerine pathotype of Alternaria alternata, which produces a host-selective toxin. Peroxisomes were observed in fungal cells by expressing a mCherry fluorescent protein tagging with conserved tripeptides serine-lysing-leucine and transmission electron microscopy. The results indicated that Pex6 plays no roles in peroxisomal biogenesis but impacts protein import into peroxisomes. The number of peroxisom...
Source: Frontiers in Microbiology - June 28, 2021 Category: Microbiology Source Type: research
Uptake of Primary Care Services and HIV and Syphilis Infection among Transgender Women attending the Tangerine Community Health Clinic, Bangkok, Thailand, 2016 - 2019
CONCLUSIONS: The increasing uptake of a transgender-specific package of services, including co-located gender affirmative hormone therapy, suggests this may be an effective model in engaging and retaining TGW in primary care. The decrease in HIV prevalence and low HIV incidence across calendar years point at a possible reduction of HIV acquisition among the TGW population served by Tangerine. The increasing prevalence of syphilis suggests ongoing high-risk sexual behaviour and underscores the need for screening and treatment for this infection at the time of delivery of HIV services.PMID:34152695 | DOI:10.1002/jia2.25683 (...
Source: Journal of the International AIDS Society - June 21, 2021 Category: Infectious Diseases Authors: Frits van Griensven Rena Janamnuaysook Oranuch Nampaisan Jitsupa Peelay Kritima Samitpol Stephen Mills Tippawan Pankam Reshmie Ramautarsing Nipat Teeratakulpisarn Praphan Phanuphak Nittaya Phanuphak Source Type: research
