2020 STD Prevention Conference September 14–24, 2020: Erratum
No abstract available (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Erratum Source Type: research

Lymphogranuloma Venereum Proctitis
No abstract available (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Photo Submission Source Type: research

Esophageal Ulcer Due to Human Papillomavirus in an HIV-Infected Patient
No abstract available (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Photo Submission Source Type: research

Perianal Reactivation of Herpes Simplex Virus Type 2 After Laser-Assisted Hair Removal
We report a case of perianal reactivation of herpes simplex virus type 2 in a 27-year-old man, who was HIV positive with good immunovirological status, after a laser-assisted (alexandrite) hair removal session. We discuss the clinical and laboratory features and the role of prophylaxis with antivirals, particularly in certain patients such as immunocompromised ones. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Case Report Source Type: research

Mycoplasma genitalium Infection in Young Women Without Urogenital Symptoms Presenting to a Community-Based Emergency Department in Birmingham, Alabama
We used the Food and Drug Administration–cleared Aptima Mycoplasma genitalium assay to evaluate for M. genitalium infection among young women without urogenital symptoms presenting to a community-based emergency department in Birmingham, Alabama, between August 2016 to August 2019 for evaluation of nongynecological concerns. M. genitalium was detected in 23 (14.8%) of 155 women. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Notes Source Type: research

Extragenital Testing for Neisseria gonorrhoeae and Chlamydia trachomatis in a Large HIV Clinic in the US South: Implementation and Epidemiology
Background Rectal and oral Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) infections are common among people with HIV, especially men who have sex with men (MSM); however, GC/CT testing rates remain low in many HIV clinics. We evaluated the real-world implementation and results of extragenital nucleic acid amplification testing for GC/CT in an urban HIV clinic. Methods Electronic health records were reviewed for all patients 18 years or older with ≥1 outpatient visit to an HIV clinic in Dallas, TX, from February 2016 to May 2019. Extragenital nucleic acid amplification testing became available in F...
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Notes Source Type: research

Estimating the Direct Medical Costs and Productivity Loss of Outpatient Chlamydia and Gonorrhea Treatment
We used 2016–2017 administrative claims data to calculate the direct medical cost and productivity loss per diagnosed case of chlamydia and gonorrhea treatment. In 2018 US dollars, the direct cost per diagnosed case was $151 for chlamydia (n = 9180) and $85 for gonorrhea (n = 3048); productivity loss was $206 (n = 31) and $246 (n = 7), respectively, among those missing work seeking care. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Notes Source Type: research

Single-Dose Azithromycin for Genital Lymphogranuloma Venereum Biovar Chlamydia trachomatis Infection in HIV-Infected Women in South Africa: An Observational Study
We conducted an observational study of lymphogranuloma venereum (LGV) biovar Chlamydia trachomatis infection in HIV-infected women in South Africa. The LGV biovar was detected in vaginal specimens of 17 (20%) of 85 women with C. trachomatis infection; 29% were symptomatic. All cases were negative for the LGV biovar after single-dose azithromycin. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Notes Source Type: research

Clinical Performance of the BD CTGCTV2 Assay for the BD MAX System for Detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis Infections
Conclusions BD CTGCTV2 performed well using a variety of sample types. As a true triplex assay, performed using a benchtop instrument, BD CTGCTV2 may be useful in settings where no testing is currently performed and in settings, such as reference laboratories, where testing turnaround time may be several days. Use of this assay at local laboratories may result in greater access to testing and a shorter time to result, which are important steps for improving our ability to combat sexually transmitted infections. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research

High Prevalence of Sexually Transmitted Infections in Pregnant Women Living in Southern Brazil
Background Porto Alegre, Brazil, has the highest rates of congenital syphilis and HIV in the country. Other treatable sexually transmitted infections (STIs) are associated with poor pregnancy and neonatal outcomes, but are only diagnosed by syndromic algorithms. Methods Between September 2018 and November 2019, we offered all pregnant women clinic-based STI testing for HIV antibody and treponemal antibody (via lateral flow assay rapid tests provided by the Brazilian Government) and for Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis (via polymerase chain reaction–based testing provi...
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research

Interpartner Concordance on Relationship Quality and Sexually Transmitted Infections Among Young Pregnant and Parenting Couples
Conclusions Findings suggest that concordant reports of relationship satisfaction and affectional expression are protective against future STI risk. Strengthening romantic relationships may be a promising strategy for preventing STIs in pregnant/parenting AYA couples. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research

Mycoplasma genitalium and Bacterial Vaginosis–Associated Bacteria in a Non–Clinic-Based Sample of African American Women
Conclusions Specific BV-associated microbes and L. iners were associated with M. genitalium, but Nugent ≥7 was not. Studies are needed to confirm a high prevalence of M. genitalium in African Americans and to understand its interactions with other vaginal bacteria. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research

High Prevalence of Chlamydia and Gonorrhea and the Need for Sexually Transmitted Infection Testing Among Men Who Have Sex With Men and Transgender Women in Papua New Guinea
Conclusions There is a large unmet need among MSM and TGW in Papua New Guinea for chlamydia and gonorrhea detection and treatment. The high prevalence of HBV reinforces the importance of ensuring introduction and scale-up of HBV treatment and immunization. Urgent efforts are needed to introduce laboratory-based diagnosis for chlamydia and gonorrhea to ensure these populations have access to much needed treatment services. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research

HIV, Sexually Transmitted Infections and Sexual Practices Among Male Sex Workers Attending a Sexual Health Clinic in Melbourne, Australia: 2010 to 2018
Conclusions Male sex workers fall into 2 groups: those who had male clients and/or noncommercial partners who have a relatively high HIV/STI positivity and those who only had female partners or clients whose HIV/STI positivity is low. Both have a high proportion of condomless sex with clients and noncommercial sex partners. Strategies to increase condom use during sex work are needed. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research

Survey of Health Care Providers’ Practices and Opinions Regarding Bacterial Sexually Transmitted Infection Testing Among Gay, Bisexual, and Other Men Who Have Sex With Men
Conclusions Promising interventions to improve bacterial STI testing included initiatives that simplify and expedite testing and expand testing delivery to other health care professionals. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research

Eligibility for HIV Preexposure Prophylaxis, Intention to Use Preexposure Prophylaxis, and Informal Use of Preexposure Prophylaxis Among Men Who Have Sex With Men in Amsterdam, the Netherlands
Conclusions Most informal PrEP users are eligible to use PrEP and have a clear sexual health care need. Especially in settings with limited PrEP access, providing the necessary care for informal PrEP users is important. The intention to use PrEP is low among PrEP-eligible STI clinic visitors. Further research should investigate modes to increase PrEP intention among PrEP-eligible persons. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research

Characteristics of the Largest Network Component of Individuals With or Exposed to Early Syphilis in Central Indiana: 2016 to 2017
Conclusions Network analysis identified a group of linked individuals most likely to be reinfected with syphilis in Central Indiana. Further investigation is needed to determine whether engaging such a high-risk group could better focus resources and decrease infections. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Original Studies Source Type: research

A Narrative Review of the Epidemiology of Congenital Syphilis in the United States From 1980 to 2019
Objectives Congenital syphilis (CS) is the result of antepartum transmission from mother to fetus of the spirochete Treponema pallidum. Although preventable through timely screening and treatment, the incidence of CS in the United States is increasing. This review describes the epidemiological trends in CS in the United States from 1980 to 2019 and characteristics of mothers of infants with CS. Methods We performed a narrative review of epidemiological studies of CS following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for reporting of observational studies in epidemiology. Qual...
Source: Sexually Transmitted Diseases - January 23, 2021 Category: Sexual Medicine Tags: Review Source Type: research

At-Home Testing for Sexually Transmitted Infections During the COVID-19 Pandemic
This report describes the program implementation to provide other sexual health clinics with a roadmap in adapting to a “new normal” in providing comprehensive sexual health care virtually to patients. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Note Source Type: research

Home-Based Testing for Sexually Transmitted Infections: Leveraging Online Resources During the COVID-19 Pandemic
No abstract available (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Commentary Source Type: research

Impact of the COVID-19 Pandemic on Sexually Transmitted Infection Clinic Visits
Coronavirus disease 2019 is responsible for a global pandemic and has impacted health care accessibility and delivery. Clinic data were reviewed for an STI clinic from September 2019 to May 2020. A significant decrease in rates of STI visits and treatments during the coronavirus disease 2019 pandemic was observed. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Notes Source Type: research

Knowing What We Do Not Know: Analysis of an Online Consultation Service to Identify Provider Knowledge Gaps in Sexually Transmitted Disease Care
The national Sexually Transmitted Diseases (STD) Clinical Consultation Network receives requests regarding complex STD cases. A total of 927 requests from Western states, 2017 to 2019, were analyzed for STD of inquiry and syphilis-specific subtopics. Syphilis requests accounted for most queries, and the number and proportion of syphilis-related requests increased significantly over time. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Notes Source Type: research

Clinical and Personal Lubricants Impact the Growth of Vaginal Lactobacillus Species and Colonization of Vaginal Epithelial Cells: An in Vitro Study
Background Vaginal lubricants are commonly used during gynecological examinations, during sexual activities, or to alleviate vaginal dryness. Many lubricants contain potentially bacteriostatic or bactericidal agents (parabens, chlorhexidine gluconate, nonoxynol-9). Our objective was to evaluate the impact of lubricants that vary in formulation on the growth and viability of vaginal Lactobacillus species and vaginal epithelial cell (VEC) colonization in an in vitro model. Methods Growth curve, disk diffusion, and minimal inhibitory assays were used to determine the impact of lubricants or excipients on the growth...
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Original Study Source Type: research

Can Machine Learning Help Identify Patients at Risk for Recurrent Sexually Transmitted Infections?
Conclusions Machine algorithms using structured EHR data did not differentiate well between patients with and without repeat STIs diagnosis. Alternative strategies, able to account for sociobehavioral characteristics, could be explored. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Original Study Source Type: research

Critical Elements of Community Engagement to Address Disparities and Related Social Determinants of Health: The Centers of Disease Control and Prevention Community Approaches to Reducing Sexually Transmitted Disease Initiative
Conclusions This study expands the community engagement literature within STD prevention, screening, and treatment by elucidating some of the critical elements of the approach and provides guidance for practitioners, researchers, and their partners as they develop, implement, and evaluate strategies to reduce STD disparities. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Original Study Source Type: research

HIV Screening Among Gonorrhea-Diagnosed Individuals; Baltimore, Maryland; April 2015 to April 2019
Conclusions Our findings suggest a considerable gap in HIV screening among individuals at elevated risk for HIV acquisition in Baltimore City, particularly among those diagnosed in emergency departments/urgent care centers/hospital settings. Future work should focus on identifying provider-level barriers to concurrent HIV/STI screening to inform provider education programs. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Original Study Source Type: research

Chlamydia Prevalence by Age and Correlates of Infection Among Pregnant Women
Conclusions Among pregnant women living in the southeastern United States, chlamydia was detected in 1 of 14 women who were tested. Chlamydia positivity was highest among women younger than 30 years. Study findings support broad screening for chlamydia in pregnancy. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Original Study Source Type: research

Women Are Less Likely to Be Tested for HIV or Offered Preexposure Prophylaxis at the Time of Sexually Transmitted Infection Diagnosis
Conclusions In patients diagnosed with bacterial STI outside of sexual health clinics, gaps in HIV prevention exist. HIV screening, multisite STI screening, and discussion of PrEP were particularly infrequent among women. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Original Study Source Type: research

Health Profession Students’ Awareness, Knowledge, and Confidence Regarding Preexposure Prophylaxis: Results of a National, Multidisciplinary Survey
Background Preexposure prophylaxis (PrEP) is a highly effective, pharmacologic method of HIV prevention. Despite its safety and efficacy, PrEP prescription remains low in those patients who are at highest risk for HIV infection. One possible reason for this may be the lack of inclusion of PrEP and HIV prevention discussions within the curricula of health professions education. Methods An online survey was administered to a cross-sectional sample of future prescribers (osteopathic/allopathic medical and physician assistant students), future nurses, and future pharmacists (n = 2085) in the United States between Ja...
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Original Study Source Type: research

Predicting Clinical Practice Change: An Evaluation of Trainings on Sexually Transmitted Disease Knowledge, Diagnosis, and Treatment
Conclusions Results suggest that longer trainings may result in more practice change than shorter trainings, recruitment of trainees should focus on those more likely to make a change in their practice, and future trainings should focus on organizational capacity building and assessing change at the organizational level. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Original Study Source Type: research

The Role of Sexually Transmitted Infections in Police as Clients Among Street-Based Female Sex Workers in Baltimore City
We examined this interaction in a 12-month longitudinal cohort study of street-based FSWs in Baltimore, MD. Methods We explored longitudinal bivariate and multivariate associations between having police clients and independent variables that focused on sexually transmitted infections (STIs), as well as demographic, structural, substance use, police interaction, and violence-related factors. Results Mean participant age was 35.8 years, 65.9% were White, and more than half (53.3%) had less than a high school education. Most (70.3%) used heroin daily, and 24.8% reported having police as clients over the study pe...
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: Original Study Source Type: research

Implementation of a Learning Collaborative Model Increases Chlamydia Screening at 37 Family Planning Clinics: Lessons Learned From 3 Cohorts
Background Chlamydia is the most commonly reported notifiable condition in the United States. Chlamydia disproportionately impacts young women and women of color. Annual screening of sexually active women 24 years and younger is recommended. Methods Between 2016 and 2019, we facilitated 3 learning collaboratives to increase chlamydia screening at a combined 37 family planning clinics funded by the Planned Parenthood Federation of America, the Office of Population Affairs in the Department of Health and Human Services, and the New York State Department of Health. We applied a consistent learning collaborative app...
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: The Real World of STD Prevention Source Type: research

Impacts of Sexually Transmitted Disease/HIV Outreach Sites on the Effectiveness of Detecting New Infections in Baltimore City, 2015 to 2018
Conclusions The findings indicated that street corners were the most successful at detecting new syphilis cases, whereas community centers were the most successful at detecting new HIV cases. However, because of the small number of new cases detected and low uptake per testing event between 2015 and 2018, STD/HIV mobile testing does not seem to be effective overall. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - December 17, 2020 Category: Sexual Medicine Tags: The Real World of STD Prevention Source Type: research

Molecular Algorithms Accurately Predict Decreased Susceptibility to Ceftriaxone in Neisseria gonorrhoeae
No abstract available (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Letters to the Editor Source Type: research

Response to Dr Robert E. Fullilove’s Editorial Letter: “Race and Sexually Transmitted Diseases…Again?”
No abstract available (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Letters to the Editor Source Type: research

Use of a Novel Couples' Verification Tool in a Male Partner Treatment Study of Women With Recurrent Bacterial Vaginosis
Verification of relationship status beyond self-report is an important aspect in sexually transmitted infection research, including partner treatment studies where primary sexual partners are targeted for enrollment. This exploratory study describes the use of a novel couples' verification tool in a male partner treatment study of women with recurrent bacterial vaginosis. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Notes Source Type: research

Characteristics of Women and Their Male Sex Partners Predict Bacterial Vaginosis Among a Prospective Cohort of Kenyan Women With Nonoptimal Vaginal Microbiota
Background Up to 50% of women with nonoptimal vaginal microbial community state type (CST) have bacterial vaginosis (BV). Little is known about what distinguishes women with and without BV diagnosis within nonoptimal CST. We identified features of women and their male sex partners associated with BV among women with nonoptimal vaginal CST. Methods In this prospective study, 252 heterosexual couples were observed at 1, 6, and 12 months after baseline. Microbiomes were characterized in cervicovaginal lavage and penile meatal swabs through high-throughput 16s ribosomal RNA gene amplicon sequencing. Nonoptimal CST w...
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Original Studies Source Type: research

Factors Associated With the Recurrence, Persistence, and Clearance of Asymptomatic Bacterial Vaginosis Among Young African American Women: A Repeated-Measures Latent Class Analysis
Conclusions Assessment of BV cases revealed distinct patterns of recurrence and persistence of BV, which were significantly associated with douching, being in the treatment arm, and being a woman who had sex with women. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Original Studies Source Type: research

Sexual Behavior and Sexually Transmitted Infection Outcomes Among Men Who Have Sex With Men and Transgender Women Participating in a Study of the Timing of Antiretroviral Therapy in Lima, Peru
Conclusions Despite reported increases in condom use, the overall high incidence of STIs reflects some ongoing condomless sex among HIV-positive men who have sex with men and transgender women, highlighting the importance of regular STI screening and counseling to support consistent condom use among HIV-positive individuals at risk for STIs. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Original Studies Source Type: research

Acceptability of a Tenofovir Disoproxil Fumarate Intravaginal Ring for HIV Pre-Exposure Prophylaxis Among Sexually Active Women
Conclusions Despite unanticipated ulcers, TDF and placebo IVRs were acceptable to some women, even when used with menses and during sex, which is promising for continued development of IVRs for HIV prevention. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Original Studies Source Type: research

Unnamed Partners From Syphilis Partner Services Interviews, 7 Jurisdictions
Conclusions Approximately 80% of sex partners were either unnamed or unreported. Partner services may be less successful at interrupting transmission in networks for men who reported sex with men where a higher proportion of partners are unnamed or unreported. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Original Studies Source Type: research

Exploring How Epidemic Context Influences Syphilis Screening Impact: A Mathematical Modeling Study
Conclusions Men who have sex with men–focused approaches to screening may be insufficient for control when there is substantial transmission in heterosexual populations. Epidemic characteristics may be useful when identifying at-risk groups for syphilis screening. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Original Studies Source Type: research

The Views of Patients and Partners Toward Patient-Delivered Partner Therapy for Chlamydia: A Systematic Review
Conclusions Because patients bear responsibility for the success of PDPT, this information is crucial in clinical settings. Acceptance, perceived and real, of PDPT was generally high. Patients are best placed to determine whether PDPT is appropriate for them, and it should be offered as an option. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Reviews Source Type: research

Sexually Transmitted Infections in Pregnancy: A Narrative Review of the Global Research Gaps, Challenges, and Opportunities
Discussion Preliminary data on harms, acceptability, and feasibility and the availability of emerging test technologies suggest that etiologic STI screening deserves further evaluation as a potential tool to improve maternal and neonatal health outcomes worldwide. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - November 14, 2020 Category: Sexual Medicine Tags: Reviews Source Type: research

Erratum: Ending the HIV Epidemic: Contributions Resulting From Syphilis Partner Services
No abstract available (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - October 13, 2020 Category: Sexual Medicine Tags: Erratum Source Type: research

Cephalosporin-Resistant Neisseria gonorrhoeae Isolated in Portugal, 2019
We report a multidrug-resistant Neisseria gonorrhoeae exhibiting resistance to ceftriaxone and cefixime, isolated in Portugal in 2019. Whole-genome sequencing was performed for typing and identification of genetic determinants of antimicrobial resistance. Because of its antimicrobial susceptibility profile, awareness should be raised for the circulation of this strain. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - October 13, 2020 Category: Sexual Medicine Tags: Case Report Source Type: research

Men and Women Repeatedly Infected With Chlamydia trachomatis Have a Lower Urogenital Bacterial Load
We assessed whether patients repeatedly infected with Chlamydia trachomatis (CT) have a lower urogenital or anorectal CT load. A CT-positive retest was independently associated with higher vaginal and higher urine Cq values (P (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - October 13, 2020 Category: Sexual Medicine Tags: Notes Source Type: research

Clearance of Mycoplasma genitalium and Trichomonas vaginalis Among Adolescents and Young Adults With Pelvic Inflammatory Disease: Results From the Tech-N Study
Current pelvic inflammatory disease (PID) treatment effectively treats Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT). However, coverage may be inadequate for Mycoplasma genitalium (MG)/Trichomonas vaginalis (TV) infections. We compared the longitudinal MG and TV outcomes with NG/CT outcomes for women enrolled in a longitudinal randomized controlled trial to optimize outcomes after PID. The prevalences of CT and NG were lower at 30- and 90-day follow-up compared with the prevalence at the time of diagnosis. No significant difference was observed for MG (odds ratio, 0.95; 0.86–1.04; P = 0.265) and TV (odds ...
Source: Sexually Transmitted Diseases - October 13, 2020 Category: Sexual Medicine Tags: Notes Source Type: research

Time to Scale Up Preexposure Prophylaxis Beyond the Highest-Risk Populations? Modeling Insights From High-Risk Women in Sub-Saharan Africa
Conclusions Preexposure prophylaxis has the potential to substantially reduce new HIV infections in HIV-endemic countries in sub-Saharan Africa. This will necessitate PrEP being made widely available beyond those at highest individual risk and continued integration into a range of national services and at community level to significantly bring down the costs and improve cost-effectiveness. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - October 13, 2020 Category: Sexual Medicine Tags: Original Studies Source Type: research

Identifying Adolescent Girls and Young Women at High Risk for HIV Acquisition: A Risk Assessment Tool From the Girl Power-Malawi Study
Conclusions A simple risk assessment tool identified a subset of AGYW in Malawi at high risk for HIV acquisition who may benefit from biomedical HIV prevention. (Source: Sexually Transmitted Diseases)
Source: Sexually Transmitted Diseases - October 13, 2020 Category: Sexual Medicine Tags: Original Studies Source Type: research