First-line Treatment Patterns and Outcomes in Advanced Non-Small Cell Lung Cancer in Sweden: A Population-based Real-world Study with Focus on Immunotherapy
Acta Oncol. 2024 Apr 21;63:198-205. doi: 10.2340/1651-226X.2024.20309.ABSTRACTBACKGROUND AND PURPOSE: The treatment landscape for patients with advanced non-small cell lung cancer (NSCLC) has evolved significantly since the introduction of immunotherapies. We here describe PD-L1 testing rates, treatment patterns, and real-world outcomes for PD-(L)1 inhibitors in Sweden.MATERIALS AND METHODS: Data were obtained from the Swedish National Lung Cancer Registry for patients with advanced NSCLC and Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0-2 who initiated first-line -systemic treatment from 01 April 201...
Source: Acta Oncologica - April 21, 2024 Category: Cancer & Oncology Authors: Gunnar Wagenius Anders Vikstr öm Anders Berglund Stina Salomonsson Goran Bencina Xiaohan Hu Dana Chirovsky Hans Brunnstr öm Source Type: research
Promising therapeutic targets for the treatment of urine storage dysfunction: what ’s the status?
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 21, 2024 Category: Drugs & Pharmacology Authors: Karl-Erik Anderssona Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USAb Department of Laboratory Medicine, Lund University, Lund, Sweden Source Type: research
Examining the dynamics between economic development, tourism, renewable energy and life expectancy in the Nordic economies
Environ Res. 2024 Apr 18:118900. doi: 10.1016/j.envres.2024.118900. Online ahead of print.ABSTRACTAs the world struggles with pressing issues like climate change and sustainable development, affecting health outcomes and environmental quality, the Nordic regionsare at the forefront of major global challenges. This paper investigates the role of human capital, renewable energy use, tourism, natural resources, and economic growth in shaping life in the Nordic region i.e., Denmark, Norway, Sweden, Finland, and Iceland).Utilizing panel data spanning from 1990 to 2020, the Driscoll and Kraay standard error (DSK) technique is em...
Source: Environmental Research - April 20, 2024 Category: Environmental Health Authors: Baozhen Dai Edwina Naa Amerley Amartei fio Francis Kyere Agyemang Kwasi Sampene Source Type: research
Psychosocial Self-efficacy and its Association with Selected Potential Factors Among Adults with Type 1 Diabetes: A Cross-Sectional Survey Study
ConclusionsIn this study, higher well-being score and lower self-reported HbA1c levels were associated with higher psychosocial self-efficacy in both univariate- and multivariate analysis and accounted for 30% of the variation in psychosocial self-efficacy in the regression model. Thus, measures to improve psychosocial self-efficacy in adults with type 1 diabetes may help maintain their psychological well-being and blood glucose control. (Source: Diabetes Therapy)
Source: Diabetes Therapy - April 20, 2024 Category: Endocrinology Source Type: research
Healthcare resource utilisation and direct medical cost for individuals with 5q spinal muscular atrophy in Sweden
Discussion and conclusionThe economic burden attributable to SMA is significant. Further research is needed to understand the burden in other European countries and the impact of new treatments. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - April 20, 2024 Category: Health Management Source Type: research
Psychosocial Self-efficacy and its Association with Selected Potential Factors Among Adults with Type 1 Diabetes: A Cross-Sectional Survey Study
ConclusionsIn this study, higher well-being score and lower self-reported HbA1c levels were associated with higher psychosocial self-efficacy in both univariate- and multivariate analysis and accounted for 30% of the variation in psychosocial self-efficacy in the regression model. Thus, measures to improve psychosocial self-efficacy in adults with type 1 diabetes may help maintain their psychological well-being and blood glucose control. (Source: Diabetes Therapy)
Source: Diabetes Therapy - April 20, 2024 Category: Endocrinology Source Type: research
Healthcare resource utilisation and direct medical cost for individuals with 5q spinal muscular atrophy in Sweden
Discussion and conclusionThe economic burden attributable to SMA is significant. Further research is needed to understand the burden in other European countries and the impact of new treatments. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - April 20, 2024 Category: Health Management Source Type: research
The global impact of SARS-CoV-2 variant BA.2.86: a comprehensive analysis with the latest developments and transmission trends - an epidemiological study
CONCLUSIONS: The SARS-CoV-2, novel variant BA.2.86, spread over six continents and 89 countries and affected 19,532 people worldwide. The disease is more prevalent in the United Kingdom, United States of America, and European countries. The detection of the disease in multiple continents and countries suggests some degree of transmissibility. Global health authorities need to rethink their policies and implement strict strategies to eradicate emerging variants and minimize the global disease burden.PMID:38639533 | DOI:10.26355/eurrev_202404_35928 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - April 19, 2024 Category: Drugs & Pharmacology Authors: S A Meo A S Meo D M Halepoto Source Type: research
Randomised controlled trial of lifestyle interventions for abdominal obesity in primary health care
Prim Health Care Res Dev. 2024 Apr 19;25:e19. doi: 10.1017/S1463423624000069.ABSTRACTAIM: Assess effects on waist circumference from diet with or without cereal grains and with or without long-term physical exercise.BACKGROUND: Elevated waist circumference is an indicator of increased abdominal fat storage and is accordingly associated with increased cardiovascular mortality. This is likely due to the association between lifestyle-induced changes in waist circumference and cardiovascular risk factors. Reductions in waist circumference may be facilitated by diet without cereal grains combined with long-term physical exercis...
Source: Primary Care - April 19, 2024 Category: Primary Care Authors: Pedro Carrera-Bastos Bj örn Rydhög Mael án Fontes-Villalba Daniel Arvidsson Yvonne Granfeldt Kristina Sundquist Tommy J önsson Source Type: research
The global impact of SARS-CoV-2 variant BA.2.86: a comprehensive analysis with the latest developments and transmission trends - an epidemiological study
CONCLUSIONS: The SARS-CoV-2, novel variant BA.2.86, spread over six continents and 89 countries and affected 19,532 people worldwide. The disease is more prevalent in the United Kingdom, United States of America, and European countries. The detection of the disease in multiple continents and countries suggests some degree of transmissibility. Global health authorities need to rethink their policies and implement strict strategies to eradicate emerging variants and minimize the global disease burden.PMID:38639533 | DOI:10.26355/eurrev_202404_35928 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 19, 2024 Category: Drugs & Pharmacology Authors: S A Meo A S Meo D M Halepoto Source Type: research
