Effectiveness and infectious complications of BCMA T ‐cell engagers in treating multiple myeloma: Real‐world evidence from Sweden
ConclusionsDespite the risk of infectious complications, the prognosis of MM patients can be significantly improved with vigilant monitoring and proactive management of infections. This real-world data highlight the potential of BCMA T-cell engagers in treating MM, emphasizing the need for careful patient monitoring to mitigate infection risks. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Katarina Uttervall,
Love T ätting,
Konstantinos Lemonakis,
Mousa Majd,
Jacob Crafoord,
Mikael Olsson,
Ulf‐Henrik Mellqvist,
Markus Hansson,
Hareth Nahi Tags: RESEARCH ARTICLE Source Type: research
Trends in incidence and treatments of spontaneous subarachnoid hemorrhage- a 10 year hospital based study
ConclusionsThe incidence of patients with SAH gradually decreased in our material, in line with national data. The treatment policy in our unit has been shifting to more use of endovascular methods. During the study period the use of hemicraniectomies decreased. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - April 22, 2024 Category: Neurosurgery Source Type: research
Remote neuropsychological assessment of patients with neurological disorders and injuries--a study protocol for a cross-sectional case-control validation study
This study protocol describes a cross-sectional study aimed at validating the newly developed digitalized neuropsychological test battery Mindmore Remote in patients with neurological disorders and injuries. Diagnoses comprise traumatic brain injury, stroke, Parkinson’s disease, multiple sclerosis, brain tumour and epilepsy. 50 patients in each patient group will be included. In addition, 50 healthy controls will be recruited. All participants will undergo both testing with Mindmore Remote at home and traditional neuropsychological assessment face-to-face in a randomised order. The primary outcome is the association ...
Source: BMJ Open - April 22, 2024 Category: General Medicine Authors: Berginström, N., Andersson, L. Tags: Open access, Neurology Source Type: research
Promising therapeutic targets for the treatment of urine storage dysfunction: what ’s the status?
. (Source: Expert Opinion on Therapeutic Targets)
Source: Expert Opinion on Therapeutic Targets - April 21, 2024 Category: Drugs & Pharmacology Authors: Karl-Erik Anderssona Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USAb Department of Laboratory Medicine, Lund University, Lund, Sweden Source Type: research
Psychosocial Self-efficacy and its Association with Selected Potential Factors Among Adults with Type 1 Diabetes: A Cross-Sectional Survey Study
ConclusionsIn this study, higher well-being score and lower self-reported HbA1c levels were associated with higher psychosocial self-efficacy in both univariate- and multivariate analysis and accounted for 30% of the variation in psychosocial self-efficacy in the regression model. Thus, measures to improve psychosocial self-efficacy in adults with type 1 diabetes may help maintain their psychological well-being and blood glucose control. (Source: Diabetes Therapy)
Source: Diabetes Therapy - April 20, 2024 Category: Endocrinology Source Type: research
Healthcare resource utilisation and direct medical cost for individuals with 5q spinal muscular atrophy in Sweden
Discussion and conclusionThe economic burden attributable to SMA is significant. Further research is needed to understand the burden in other European countries and the impact of new treatments. (Source: The European Journal of Health Economics)
Source: The European Journal of Health Economics - April 20, 2024 Category: Health Management Source Type: research
Psychosocial Self-efficacy and its Association with Selected Potential Factors Among Adults with Type 1 Diabetes: A Cross-Sectional Survey Study
ConclusionsIn this study, higher well-being score and lower self-reported HbA1c levels were associated with higher psychosocial self-efficacy in both univariate- and multivariate analysis and accounted for 30% of the variation in psychosocial self-efficacy in the regression model. Thus, measures to improve psychosocial self-efficacy in adults with type 1 diabetes may help maintain their psychological well-being and blood glucose control. (Source: Diabetes Therapy)
Source: Diabetes Therapy - April 20, 2024 Category: Endocrinology Source Type: research
Occupational balance and associated factors among students during higher education within healthcare and social work in Sweden: a multicentre repeated cross-sectional study
Conclusions
The association between higher levels of OBQ11 and lower levels of health and well-being is remarkable. There is a need for more research on this contradiction and what it means for students’ health and well-being in the long run. (Source: BMJ Open)
Source: BMJ Open - April 19, 2024 Category: General Medicine Authors: Larsson, M., Ahlstrand, I., Larsson, I., Lood, Q., Hammar, I. A., Sundler, A. J., Pennbrant, S., Ekman, A., Forsberg, E., Heden, L., Nunstedt, H., Sterner, A., Hallgren, J. Tags: Open access, Occupational and environmental medicine Source Type: research
Are there lost opportunities in chronic kidney disease? A region-wide cohort study
Conclusions
While we noted underdiagnosis and undertreatment of CKD in this large contemporary population, we also identified a substantial realisable potential to improve CKD outcomes and reduce its burden by treating patients early with guideline-directed pharmacological therapy. (Source: BMJ Open)
Source: BMJ Open - April 19, 2024 Category: General Medicine Authors: Sundström, J., Norhammar, A., Karayiannides, S., Bodegard, J., Gustafsson, S., Cars, T., Eriksson Svensson, M., Ärnlöv, J. Tags: Open access, Epidemiology Source Type: research
Undiagnosed type 2 diabetes is common – intensified screening of established risk groups is imperative in Sweden: the SDPP cohort
Undiagnosed type 2 diabetes (T2D) is a global problem. Current strategies for diagnosis in Sweden include screening individuals within primary healthcare who are of high risk, such as those with hypertension, ... (Source: BMC Medicine)
Source: BMC Medicine - April 19, 2024 Category: Internal Medicine Authors: Hrafnhildur Gudjonsdottir, Per Tynelius, Nouha Saleh Stattin, Diego Yacam án Méndez, Anton Lager and Boel Brynedal Tags: Research article Source Type: research
‘We get to learn as we move’: effects and feasibility of lesson-integrated physical activity in a Swedish primary school
Physical activity (PA) promotes health in adults as well as children. At the same time, a large proportion of children do not meet the recommendations for PA, and more school-based efforts to increase PA are n... (Source: BMC Public Health)
Source: BMC Public Health - April 19, 2024 Category: Consumer Health News Authors: Robert Larsson, Eva Ljung, Sara Josefsson and Thomas Ljung Tags: Research Source Type: research
Work-, lifestyle-, and health-related factors among women and men working in the emergency medical services
Conclusions. Exposure to work-related factors that might affect health was common among ambulance personnel. Lifestyle- and health-related factors were somewhat contradictory, with a low proportion reporting lifestyle-related risk factors, but a high proportion having risk factors for CVD.PMID:38632949 | DOI:10.1080/10803548.2024.2332115 (Source: International Journal of Occupational Safety and Ergonomics)
Source: International Journal of Occupational Safety and Ergonomics - April 18, 2024 Category: Occupational Health Authors: Anna M Johnsen Petra Wagman Anders Brostr öm Eleonor I Fransson Source Type: research
Swedish maternity care professionals' perception of labor induction
CONCLUSIONS: Labor inductions might pose challenges to midwives and could bring to light underlying tensions between obstetricians/gynecologists and midwives. Given the modest response rate of the study, we cautiously suggest that while the development of new maternity care guidelines should be grounded in evidence, they should also embrace concerns and insights from a diversity of professional perspectives.PMID:38636350 | DOI:10.1016/j.midw.2024.103997 (Source: Midwifery)
Source: Midwifery - April 18, 2024 Category: Midwifery Authors: Gabriel Raoust Stefan Rocco Hansson Petri Kajonius Source Type: research
Cystatin C as an adjunct to HbA1c may prove useful in predicting the development of diabetic complications in children and adolescents with type 1 diabetes
ConclusionIn conclusion, Cystatin C levels were higher in patients with diabetes duration longer than 5 years, and inverse correlation was found between HbA1c and Cystatin C levels as well as duration of diabetes. Cystatin C may prove useful as an adjunct to HbA1c in predicting eventual development of diabetic complications. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - April 18, 2024 Category: Endocrinology Source Type: research
The Promise of a Longer Lifetime
Modern hygiene has been described as the reaction against the old fatalistic creed that deaths inevitably occur at a constant rate. The study of vital statistics shows that there is no “iron law of mortality.” According to a report prepared for the National Conservation Commission fifteen years ago, statistics for India showed that the average duration of life there was less than twenty-five years. In Sweden it was over fifty years; in Massachusetts, forty-five years. The leng th of life is increasing wherever sanitary science and preventive medicine are applied. In India it is stationary. In Europe it doubled in three...
Source: JAMA - Journal of the American Medical Association - April 18, 2024 Category: General Medicine Source Type: research
