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Total 2969 results found since Jan 2013.
The Riga East University Hospital Stroke Registry-An Analysis of 4915 Consecutive Patients with Acute Stroke
Conclusions: Our stroke registry data are comparable to those of other major registries. Analysis of stroke registry data is important for improving stroke care and obtaining additional information for stroke studies.PMID:34207100 | PMC:PMC8233796 | DOI:10.3390/medicina57060632
Source: Medicina (Kaunas) - July 2, 2021 Category: Universities & Medical Training Authors: Guntis Karelis Madara Micule Evija Klavina Iveta Haritoncenko Ilga Kikule Biruta Tilgale Inese Polaka Source Type: research
Association of ischemic stroke onset time with presenting severity, acute progression, and long-term outcome: A cohort study
ConclusionsNight-onset strokes, compared with day-onset strokes, are associated with higher presenting neurologic severity, more frequent END, and worse 3-month functional outcome. These findings suggest that circadian time of onset is an important additional variable for inclusion in epidemiologic natural history studies and in treatment trials of neuroprotective and reperfusion agents for acute ischemic stroke.
Source: PLoS Medicine - February 4, 2022 Category: Internal Medicine Authors: Wi-Sun Ryu Source Type: research
Elevated inflammatory markers predict mortality in long-term ischemic stroke-survivors: a population-based prospective study.
CONCLUSIONS: Fibrinogen and IL-6 were independent predictors of mortality in long-term stroke-survivors, whereas elevated hs-CRP predicted mortality in stroke-free subjects. Mortality risk prediction in stroke-survivors differed from that of stroke-free subjects.
PMID: 27146666 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - May 3, 2016 Category: Geriatrics Authors: Frøyshov HM, Bjørnerem Å, Engstad T, Halvorsen DS Tags: Aging Clin Exp Res Source Type: research
Temporal Trends and Predictors of Drug Utilization and Outcomes in First-Ever Stroke Patients: A Population-Based Study Using the Singapore Stroke Registry
ConclusionsPrescription of secondary stroke preventive medications (particularly in ischemic stroke) was associated with more favorable outcomes, highlighting the importance of physician adherence to evidence-based pharmacotherapy.
Source: CNS Drugs - July 15, 2019 Category: Neurology Source Type: research
Statin Effects in Atrial Fibrillation-Related Stroke: A Systematic Review and Meta-Analysis
Conclusions: Statin therapy for AF-related stroke may reduce all-cause mortality and improve functional outcomes. Randomized controlled studies are warranted to confirm the effects of statins on the outcomes of AF-related stroke.
Source: Frontiers in Neurology - October 9, 2020 Category: Neurology Source Type: research
Polymorphism of IL-1B rs16944 (T/C) associated with serum levels of IL-1 β affects seizure susceptibility in ischemic stroke patients
CONCLUSIONS: The IL-1B rs16944 polymorphism had an independent association with seizure susceptibility after ischemic stroke. The mechanism might be associated with the regulation of IL-1β levels.PMID:36089763 | DOI:10.17219/acem/152738
Source: Adv Data - September 12, 2022 Category: Epidemiology Authors: Xiaojun Ma Liangwei Sun Xiaoli Li Yanlu Xu Qingyan Zhang Source Type: research
Effect of 20 mg/day Atorvastatin: Recurrent Stroke Survey in Chinese Ischemic Stroke Patients with Prior Intracranial Hemorrhage.
CONCLUSIONS: Medication with 20 mg/day atorvastatin may be beneficial in reducing ischemic stroke recurrence in ischemic stroke patients with a history of ICH and is not associated with an increased risk of ICH recurrence.
PMID: 23894236 [PubMed]
Source: Journal of Clinical Neurology - December 2, 2014 Category: Neurology Tags: J Clin Neurol Source Type: research
Sex differences in outcomes after stroke among patients with low total cholesterol levels: a large hospital-based prospective study
ConclusionsThese findings suggest that patients (both men and women) with atherothrombotic infarction who have low TC levels would not benefit from receiving statin treatment. Therefore, it is crucial to explore the impact of statin treatment on outcomes in Asian patients, especially Chinese patients with atherothrombotic and low TC levels, in order to improve outcomes after stroke and reduce the disease burden.
Source: Biology of Sex Differences - November 23, 2016 Category: Biology Source Type: research
Anti-inflammatory treatment and risk for depression after first-time stroke in a cohort of 147 487 Danish patients.
CONCLUSION: Anti-inflammatory treatment is associated with a lower risk for depression shortly after stroke but a higher risk for late depression. This suggests that inflammation contributes differently to the development of depression after stroke depending on the time of onset.
PMID: 28632121 [PubMed - as supplied by publisher]
Source: Journal of Psychiatry and Neuroscience - June 22, 2017 Category: Psychiatry Tags: J Psychiatry Neurosci Source Type: research
Suboptimal lipid management before and after ischaemic stroke and TIA —the North Dublin Population Stroke Study
ConclusionsIn this population-based study, LLT recommended by international guidelines was under-used, before and after index stroke/TIA. Strategies to improve adherence are needed.
Source: Irish Journal of Medical Science - January 24, 2018 Category: General Medicine Source Type: research
Statin treatment before stroke reduces pro-inflammatory cytokine levels after stroke.
CONCLUSION: Stroke induces changes in the RhoA-ROCK pathway in T-cells. CRP and NIHSS score correlated positively in the study. Statins may have an anti-inflammatory effect as statin treatment before stroke reduces post-stroke pro-inflammatory levels. RhoA GTPase and its downstream effectors are possibly the key to improve statin treatment in stroke.
PMID: 30574850 [PubMed - as supplied by publisher]
Source: Neurological Research - December 24, 2018 Category: Neurology Tags: Neurol Res Source Type: research
Characteristics and Factors for Short-Term Functional Outcome in Stroke Patients With Atrial Fibrillation, Nationwide Retrospective Cohort Study
Conclusion: Our results suggest that presence of non-relevant extracranial cerebral atherosclerosis may affect poor functional outcome and prior stroke statin therapy may be feasible in Korean stroke patients with AF.
Source: Frontiers in Neurology - October 17, 2019 Category: Neurology Source Type: research
