Filtered By:
Education: Study
Therapy: Statin Therapy

This page shows you your search results in order of relevance. This is page number 5.

Order by Relevance | Date

Total 2969 results found since Jan 2013.

Demographic and Clinical Predictors of Leptomeningeal Collaterals in Stroke Patients
Background: Leptomeningeal collaterals improve outcome after stroke, including reduction of hemorrhagic complications after thrombolytic or endovascular therapy, smaller infarct size, and reduction in symptoms at follow-up evaluation. The purpose of this study was to determine the demographic and clinical variables that are associated with a greater degree of cerebral collaterals.Methods: Clinical data of patients presenting with M1 occlusions of the middle cerebral artery (MCA) and associated computed tomography angiography studies after admission from 3 separate institutions were retrospectively compiled (n = 82). Occl...
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Nitin Malik, Qinghua Hou, Achala Vagal, James Patrie, Wenjun Xin, Patrik Michel, Ashraf Eskandari, Tudor Jovin, Max Wintermark Tags: Original Articles Source Type: research

Subsequent Vascular Events after Ischemic Stroke: The Japan Statin Treatment Against Recurrent Stroke—Longitudinal
We undertook a multicenter cohort observational study to investigate the frequency and type of subsequent vascular events after an ischemic stroke and to compare the rates of vascular events between patients with and without hyperlipidemia.
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2014 Category: Neurology Authors: Eiichi Nomura, Akifumi Suzuki, Isao Inoue, Jyoji Nakagawara, Kazuo Takahashi, Tetsuya Takahashi, Yasuhiro Manabe, Chiaki Yokota, Kazunori Okada, Tetsuhiro Nishihara, Yasumasa Yamamoto, Koichi Noda, Shinichi Takahashi, Setsuro Ibayashi, Makoto Takagi, Kazu Source Type: research

The Effects of Previous Statin Treatment on Plasma Matrix Metalloproteinase-9 Level in Chinese Stroke Patients Undergoing Thrombolysis
It is unclear whether previous statin therapy influences the prognosis, hemorrhagic transformation, and plasma matrix metalloproteinases (MMP)-9 levels in Chinese stroke patients receiving intravenous thrombolysis. We conduct a prospective cohort study of 193 patients treated with intravenous thrombolysis. All the enrolled patients were divided into 2 groups (the control group and the statin group), according to the previous history of statin use. The plasma MMP-9 levels were detected before and at 6 hours, 12 hours, 24 hours, and 72 hours after intravenous thrombolysis.
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2014 Category: Neurology Authors: Hong-Dong Zhao, Ying-Dong Zhang Source Type: research

Effect of Inflammation on the Process of Stroke Rehabilitation and Poststroke Depression
Conclusions Stroke comprises ischemic stroke and ICH. The immuno-inflammatory process is involved in neural plasticity following events such as a hemorrhage or ischemic stroke. After ischemia, astrocytes, microglia, and MDMs play important roles during rehabilitation with the modulation of cytokines or chemokines, such as TNF-α and IL-1. Moreover, MiRNAs are also important posttranscriptional regulators in these glial mitochondrial responses to cerebral ischemia. ICH involves processes similar and different to those seen in ischemia, including neuronal injury, astrocytic and microglial/macrophage activation, and n...
Source: Frontiers in Psychiatry - April 10, 2019 Category: Psychiatry Source Type: research

Combining Human Umbilical Cord Blood Cells With Erythropoietin Enhances Angiogenesis/Neurogenesis and Behavioral Recovery After Stroke
In conclusion, our results suggest that hUCBC infusion in combination with EPO administration demonstrates therapeutic efficacy in the treatment of stroke-induced injury by promoting neurogenesis and angiogenesis. Further research that delineates the therapeutic mechanism of systemically administered hUCBC and EPO is required. Ethics Statement All experimental procedures involving animals were performed in accordance with the Guide for the Care and Use of Laboratory Animals as adopted and promulgated by the U. S. National Institutes of Health and were approved by CHA University Institutional Animal Care & Use Com...
Source: Frontiers in Neurology - April 9, 2019 Category: Neurology Source Type: research

Stroke risk 'higher at start of warfarin treatment'
Conclusion This study has found that warfarin was associated with an increased risk of ischaemic stroke during the first 30 days of treatment. After 30 days of treatment, warfarin was associated with a decreased risk of stroke. However, this study has a number of limitations that should be considered: All information was from patient records, which means that it wasn't subject to recall bias, but the information may not be complete – we do not know if, for example, people took the medication they were prescribed. There may be other factors (confounders) that explain the association seen. In particular, the ba...
Source: NHS News Feed - December 19, 2013 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

Stroke Down to Fifth-Leading Killer in U.S. -- Here's What the Statistical Change Really Means
In the 1970s, Joseph Broderick was a resident at the Mayo Clinic in need of a focus for his fellowship. He decided to give stroke research a try. Part of the lure was all the unanswered questions, like: Who is most likely to have a stroke? Why do they have it when others seemingly like them don't? Is stroke getting more or less common? What can be done to prevent it? Another part of the lure was a landmark study on the frequency of stroke being done in the hospital's hometown of Rochester, Minnesota. Being part of it meant working for one of the nation's leading stroke researchers at the time, Jack Whisnant. By the mid-...
Source: Healthy Living - The Huffington Post - January 12, 2015 Category: Consumer Health News Source Type: news

Researcher Studies Statins for Stroke Therapy
Stacy Pigott A $2.8 million grant may help develop an improved therapeutic treatment for acute ischemic stroke patients to let them recover faster with fewer long-term complications. The protocol hinges on effectively delivering statins to the brain, where their neuroprotective properties can help save tissue damaged by stroke. Aug. 7, 2020 University of Arizona Health Sciencesnhg-PATRICK-RONALDSON_DSC6492-web.jpg Patrick Ronaldson (right), associate professor in the College of Medicine – Tucson's Department of Pharmacology, and doctoral students Erica Williams and Robert Betterton discuss their latest researc...
Source: The University of Arizona: Health - August 6, 2020 Category: Universities & Medical Training Authors: mittank Source Type: research

How People With Diabetes Can Lower Stroke Risk
After spending nearly two decades trying to manage her Type 2 diabetes, Agnes Czuchlewski landed in the emergency room in 2015, with news that she’d just experienced a heart attack. She also learned that she had metabolic syndrome, a cluster of conditions that includes diabetes but also brings higher risk of heart disease and stroke. “Because I needed to lose quite a bit of weight when I was first diagnosed, I was focused on the number I saw on the scale, and then on my blood-sugar numbers,” recalls Czuchlewski, 68, who lives in New York City. “I didn’t realize other numbers came into play, li...
Source: TIME: Health - November 10, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Disease healthscienceclimate Source Type: news

Differences in the knowledge and compliance with secondary prevention of stroke between transient ischaemic attack patients with and without subsequent stroke
ConclusionsThe transient ischaemic attack patients with subsequent stroke exhibit a higher identification rate of most of the warning signs of stroke and a better compliance with antiplatelet agents and statins therapy of stroke compared with those without subsequent stroke. Thus, we suggest that transient ischaemic attack patients should receive additional health education to increase their awareness of the harms of stroke. Relevance to clinical practiceClinicians should be aware of conducting different health education to patients with transient ischaemic attack and stroke. Also, it is important to give health education ...
Source: Journal of Clinical Nursing - January 21, 2014 Category: Nursing Authors: Jingjing Zhao, Muke Zhou, Jian Guo, Jingjing Zhang, Yaqiong Yang, Fan Yu, Li He Tags: Original Article Source Type: research

Influence of Statin Pretreatment on Initial Neurological Severity and Short-Term Functional Outcome in Acute Ischemic Stroke Patients: The Fukuoka Stroke Registry
This study aimed at determining these associations in ischemic stroke patients. Methods: Among patients registered in the Fukuoka Stroke Registry from June 2007 to October 2014, 3,848 patients with ischemic stroke within 24 h of onset, who had been functionally independent before onset, were enrolled in this study. Ischemic stroke was classified as cardioembolic or non-cardioembolic infarction. Primary and secondary study outcomes were mild neurological symptoms defined as a National Institutes of Health Stroke Scale score of ≤4 on admission and favorable functional outcome defined as a modified Rankin Scale score of ≤...
Source: Cerebrovascular Diseases - July 4, 2016 Category: Neurology Source Type: research

U ‐curve relation between cholesterol and prior ischemic stroke
ConclusionOur hypothesis was falsified. The association between lower cholesterol levels and higher frequency of prior ischemic stroke in patients with cholesterol <5.5 mmol/L cannot be solely an effect of aggressive statin treatment in patients with prior ischemic stroke, as the association pertained also to patients who did not use statin. Previous studies on ischemic stroke patients have shown conflicting results concerning the association between cholesterol level and patient outcome. We hypothesized that acute ischemic stroke patients with increased cholesterol on admission more frequently had experienced prior i...
Source: Brain and Behavior - August 31, 2016 Category: Neurology Authors: Gerd Haga Bringeland, Aliona Nacu, Ulrike Waje ‐Andreassen, Lars Thomassen, Halvor Naess Tags: Original Research Source Type: research

Survivability of patients admitted for stroke in a primary stroke center, Penang, Malaysia: a retrospective 5-year study
CONCLUSION: The findings of the study are intended to encourage more non-stroke hospitals in Malaysia to increase their efforts in treating stroke patients, as early treatment can help reduce the severity of the stroke. With the incorporation of evidence-based data, this study also contributes to local data for comparison and improves the implementation of regularly prescribed stroke medication.PMID:37131240 | DOI:10.1186/s40360-023-00669-8
Source: BMC Pharmacology and Toxicology - May 2, 2023 Category: Drugs & Pharmacology Authors: Monica Danial Nurul Shahira Izwani Mohdradzi Amer Hayat Khan Alan Swee Hock Ch'ng Looi Irene Source Type: research