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The Incidence Of Secondary Stroke Prevention Medication Following Hospitalization For Ischemic Stroke (P5.005)
CONCLUSIONS:The incidence of statins and ACE-I/ARB initiation following a stroke, among older adults discharged home was low (24-35%). Reported rates of side effects of either class of medications are not high enough to account for the low observed incidence. Better understanding of why beneficiaries are not receiving SSP, namely statins and ACE-I/ARBs, within 90 days of an ischemic stroke is critical to preventing recurrent stroke.Study Supported by:UnfundedDisclosure: Dr. Blackburn has nothing to disclose. Dr. Zhao has nothing to disclose. Dr. Kilgore has nothing to disclose. Dr. Albright has received research support fr...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Blackburn, J., Zhao, H., Kilgore, M., Albright, K. Tags: Cerebrovascular Disease and Interventional Neurology II Source Type: research

Increasing compliance with national quality measures for stroke through use of a standard order set.
CONCLUSION: A retrospective review of the treatment records of patients hospitalized for acute stroke showed that adherence to national guidelines was increased when providers used a standard order set. PMID: 25991597 [PubMed - in process]
Source: American Journal of Health-System Pharmacy : AJHP - May 21, 2015 Category: Drugs & Pharmacology Authors: Elder KG, Lemon SK, Costello TJ Tags: Am J Health Syst Pharm Source Type: research

Processes and outcomes of ischemic stroke care: the influence of hospital level of care
Conclusions Outcomes among patients with ischemic stroke can be improved by thrombolytic therapy, antithrombotic therapy, statin treatment and rehabilitation assessment. Among patients with ischemic stroke, admission to designated stroke center hospitals may be associated with lower mortality through better processes of care.
Source: International Journal for Quality in Health Care - July 31, 2015 Category: Global & Universal Authors: Tung, Y.-C., Jeng, J.-S., Chang, G.-M., Chung, K.-P. Tags: Papers Source Type: research

Lowering C-reactive protein with statins after an ischemic stroke avoids mortality and readmissions. A prospective cohort study.
CONCLUSIONS: Therapy with statins, either previous or early initiation, after an ischemic stroke, could improve the survival and readmission rates by lowering both cholesterol and hsCRP levels. PMID: 25895539 [PubMed - indexed for MEDLINE]
Source: Annals of Medicine - February 18, 2016 Category: Internal Medicine Tags: Ann Med Source Type: research

Poor Adherence to Statin and Antihypertensive Therapies as Risk Factors for Fatal Stroke
ConclusionsIndividuals with hypercholesterolemia and hypertension who fail to take their prescribed statin and antihypertensive medication experience a substantially increased risk of fatal stroke. The risk is lower if the patient is adherent to either one of these therapies.
Source: Journal of the American College of Cardiology - March 29, 2016 Category: Cardiology Source Type: research

COLADAS: Caribbean Origin Latin Americans Disparities in Acute Stroke (I5.006)
Conclusions: Our study reveals intrinsic sex differences that may imply under treatment. Understanding the reasons underlying these "sex-gaps" is critical. Study Supported By: Award Number Grants 5S21MD000242 and 5S21MD000138, from the National Center for Minority Health and Health Disparities, National Institutes of Health (NCMHD-NIH).Disclosure: Dr. Teron Molina has nothing to disclose. Dr. Rodríguez Centeno has nothing to disclose. Dr. Santiago has nothing to disclose. Dr. López Valentín has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Teron Molina, I., Rodriguez Centeno, A., Santiago, F., Lopez Valentin, M. Tags: Sex-related Factors in Neurological Disease Data Blitz Presentations Source Type: research

Get Rid of Toxins to Reduce Risk of Stroke
Effects of Toxins I’ve been warning you about the toxins in our environment for years. They cause inflammation… They make you gain weight… They cause you to feel fatigued… Our exposure to them starts before we’re even born. One study found 287 chemicals and toxins in the blood of newborn babies.1 It’s shocking. What is in the air we breathe? We breathe in toxins and air pollutants every day. Carbon dioxide, lead, nitrogen oxide, sulfur dioxide, and particulate matter (PM). Causes of Stroke Now, a new study reveals that air pollution is responsible for as many as one-third of all strokes.2 That’...
Source: Al Sears, MD Natural Remedies - July 15, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news

Changes in pre-hospital management of vascular risk factors among patients admitted due to recurrent stroke in Poland from 1995 to 2013.
CONCLUSIONS: Our data indicate a clear overall improvement of secondary stroke prevention. However, persistent use of antithrombotic drugs and tobacco smoking after the first ischemic stroke is constantly suboptimal. PMID: 27482236 [PubMed]
Source: Archives of Medical Science - August 4, 2016 Category: Journals (General) Tags: Arch Med Sci Source Type: research

Effect of statin use on clinical outcomes in ischemic stroke patients with atrial fibrillation
The objective of this study was to clarify whether statin therapy can influence the prognosis in recent ischemic stroke patients with atrial fibrillation. We identified ischemic stroke patients with atrial fibrillation between 2001 and 2011 from Taiwan National Health Insurance Database. Patients not treated with statins during the first 90 days after the index stroke were matched to patients treated with statins in the first 90 days in a 2:1 ratio on the basis of age, sex, hypertension, diabetes mellitus, ischemic heart disease, heart failure, estimated National Institutes of Health Stroke Scale, use of anticoagulant, an...
Source: Medicine - February 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Secondary prevention treatment after acute stroke in older South Asian, Chinese and other Canadians: a retrospective data analysis.
Abstract BACKGROUND: Little is known about whether there are differences in medication use between older patients of Chinese descent, those of South Asian descent and other Canadian patients after acute ischemic or primary intracerebral hemorrhagic stroke. The aim of this population-based study was to evaluate potential ethnic differences in secondary prevention pharmacotherapy after acute stroke. METHODS: Using health administrative data, we conducted a retrospective analysis of all patients aged 66 years or more admitted to hospital with acute stroke in Ontario (1997-2011) and British Columbia (1997-2009). ...
Source: cmaj - September 11, 2017 Category: General Medicine Authors: Khan NA, McAlister FA, Pilote L, Palepu A, Quan H, Hill MD, Fang J, Kapral MK Tags: CMAJ Open Source Type: research

The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK)
ConclusionsHigher plasma PAr was independently associated with increased risk of incident stroke in all participants and across all subgroups stratified by conventional risk predictors. Our novel findings point to and expand the range of inflammation and immune activation processes that may be relevant for the pathogenesis and prevention of stroke. This trial was registered at clinicaltrials.gov as NCT03013725.
Source: American Journal of Clinical Nutrition - January 26, 2018 Category: Nutrition Source Type: research

237 Systematic Review of Fibrinogen and Risk of Recurrent Stroke and Vascular Events after Ischaemic Stroke or Transient Ischaemic Attack (TIA)
ConclusionThe prognostic value of Fibrinogen after stroke or TIA remains unclear. Standardised methods and fully-adjusted multivariable analysis are needed in future prognostic studies.
Source: Age and Ageing - September 16, 2019 Category: Geriatrics Source Type: research

Effect of Statin on Stroke Recurrence Prevention at Different Infarction Locations: A Post Hoc Analysis of The J-STARS Study.
CONCLUSIONS: Pravastatin significantly reduced the recurrence rate of all stroke among patients with PCS. Thus, the effect of statin on the recurrence of stroke may differ according to infarction location. PMID: 31554765 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - September 27, 2019 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Positive Influence of Stroke Health Manager on Risk Factors Control and Medication Adherence After Ischemic Stroke
Conclusions: Stroke health manager intervention improved the control of blood pressure, LDL-C, glucose levels and the persistence for secondary prevention medications 3 months after discharge.
Source: Frontiers in Neurology - March 10, 2020 Category: Neurology Source Type: research

Effects of statin therapy on outcomes of ischemic stroke: a real-world experience in Brazil
Conclusions: Statins play an important role in the treatment of ischemic stroke, preventing stroke recurrence and cardiovascular events, and improving functional performance.RESUMO Introdu ção: A terapia com estatinas tornou-se um dos avanços mais importantes na prevenção secundária do acidente vascular cerebral (AVC). Objetivo: Fornecer evidências de dados do mundo real para avaliar associações detalhadas entre a prevenção secundária do AVC e o uso de estatinas no Bras il. Métodos: Realizamos um estudo de coorte prospectivo, incluindo pacientes consecutivos com diagnóstico de AVC isquêmico. Os indivíduos f...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research