Statin treatment before stroke reduces pro-inflammatory cytokine levels after stroke.

CONCLUSION: Stroke induces changes in the RhoA-ROCK pathway in T-cells. CRP and NIHSS score correlated positively in the study. Statins may have an anti-inflammatory effect as statin treatment before stroke reduces post-stroke pro-inflammatory levels. RhoA GTPase and its downstream effectors are possibly the key to improve statin treatment in stroke. PMID: 30574850 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30574850?dopt=Abstract

Source: Neurological Research - December 24, 2018 Category: Neurology Tags: Neurol Res Source Type: research