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Therapy: Radiation Therapy

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Total 256 results found since Jan 2013.

Microvascular free tissue reconstruction in the multiply irradiated patient
Conclusion: Microvascular free tissue transfer to the head and neck is expected to provide a successful reconstruction in patients who have received multiple courses of radiation who develop second primary tumors, recurrence of disease, or who suffer from late complications of their radiation therapy.
Source: The Laryngoscope - March 20, 2014 Category: ENT & OMF Authors: Eli A. Gordin, Yadranko Ducic Tags: Original Report Source Type: research

Predictors of functional recovery in adults with posterior fossa ependymomas.
Conclusions Greater extent of resection and adjuvant radiotherapy significantly improve PFS in adult patients with posterior fossa ependymomas. Tumor size, cystic changes, and the need for CSF diversion were independent predictors of the rate of functional recovery in this patient population. Taken together, these functional outcome predictors may guide preoperative estimations of recovery following microsurgical resection. PMID: 24579660 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 28, 2014 Category: Neurosurgery Authors: Mirzadeh Z, Bina R, Kusne Y, Coons SW, Spetzler RF, Sanai N Tags: J Neurosurg Source Type: research

Stroke-Like Migraine Attacks after Radiation Therapy (SMART) Syndrome Is Not Always Completely Reversible: A Case Series FELLOWS' JOURNAL CLUB
SUMMARY: We retrospectively reviewed clinical and imaging findings in 11 patients with stroke-like migraine attacks after radiation therapy (SMART) syndrome to better understand this disorder previously thought to be reversible. Six men and 5 women had complex bouts of neurologic impairment beginning, on average, 20 years after cerebral irradiation. All had characteristic, unilateral gyriform enhancement on MR imaging that developed within 2–7 days and typically resolved in 2–5 weeks. Unlike prior reports, 45% had incomplete neurologic recovery manifesting as dysphasia, cognitive impairment, or hemiparesis. The...
Source: American Journal of Neuroradiology - December 13, 2013 Category: Radiology Authors: Black, D. F., Morris, J. M., Lindell, E. P., Krecke, K. N., Worrell, G. A., Bartleson, J. D., Lachance, D. H. Tags: FELLOWS ' JOURNAL CLUB Source Type: research

Stroke in Children With Cancer: The Tip of the Iceberg?
We read with great interest the article by Noje et al. in which they analyzed the incidence and characteristics of stroke in children with cancer. Among a population of 1411 children with cancer, during a 10-year period registry, 15 children had stroke, corresponding to an overall prevalence of 1%. A slightly increased prevalence of stroke in children with brain tumors was documented (1.3%). The occurrence of stroke in children with brain tumors is potentiated by cranial radiation therapy. We are currently following a cohort of 103 adult survivors of childhood primary central nervous system tumors in our neurooncology c...
Source: Pediatric Neurology - December 6, 2013 Category: Neurology Authors: João Passos, Hipólito Nzwalo, Joana Marques, Ana Azevedo, Sofia Nunes, Duarte Salgado Tags: Letters to the Editor Source Type: research

Proton therapy for reirradiation of progressive or recurrent chordoma.
CONCLUSIONS: Full-dose proton reirradiation provided encouraging initial disease control and overall survival for patients with recurrent or progressive chordoma, although additional toxicities may develop with longer follow-up times. PMID: 24267972 [PubMed - in process]
Source: Health Physics - November 28, 2013 Category: Physics Authors: McDonald MW, Linton OR, Shah MV Tags: Int J Radiat Oncol Biol Phys Source Type: research

Proton Therapy for Reirradiation of Progressive or Recurrent Chordoma
Conclusions: Full-dose proton reirradiation provided encouraging initial disease control and overall survival for patients with recurrent or progressive chordoma, although additional toxicities may develop with longer follow-up times.
Source: International Journal of Radiation Oncology * Biology * Physics - November 23, 2013 Category: Radiology Authors: Mark W. McDonald, Okechuckwu R. Linton, Mitesh V. Shah Tags: Central Nervous System Tumors Source Type: research

Branch retinal artery occlusion following radiation therapy to the head and neck: a case report
Conclusion: This case demonstrates that patients receiving radiation to the head and neck may be at increased risk for developing a BRAO secondary to atherosclerotic changes of vessels adjacent to the radiation target. Given this risk, it may be reasonable to obtain carotid artery imaging in patients with a history of cervical radiation who present with sudden or transient visual field defects, even in the absence of other conventional risk factors for atherosclerosis.
Source: BMC Ophthalmology - Latest articles - November 1, 2013 Category: Opthalmology Authors: Helen JiangMaxwell StemJerome Finkelstein Source Type: research

Moyamoya Disease Associated with Asymptomatic Mosaic Turner Syndrome: A Rare Cause of Hemorrhagic Stroke
We present the first reported case of an adult patient with previously unrecognized mosaic Turner syndrome with acute subarachnoid and intracerebral hemorrhage as the initial manifestation of moyamoya syndrome. A 52-year-old woman was admitted with a subarachnoid hemorrhage with associated flame-shaped intracerebral hemorrhage in the left frontal lobe. Physical examination revealed short stature, pectus excavatum, small fingers, micrognathia, and mild facial dysmorphism. Cerebral angiography showed features consistent with bilateral moyamoya disease, aberrant intrathoracic vessels, and an unruptured 4-mm right superior hyp...
Source: Journal of Stroke and Cerebrovascular Diseases - October 7, 2013 Category: Neurology Authors: Sunil Manjila, Benjamin R. Miller, Anitha Rao-Frisch, Balint Otvos, Anna Mitchell, Nicholas C. Bambakidis, Michael A. De Georgia Tags: Case Reports Source Type: research

Acute late-onset encephalopathy after radiotherapy: An unusual life-threatening complication
Unusual late-onset complications of brain irradiation, characterized by reversible neurologic focal signs, seizures, and MRI alterations, have recently been reported and classified as stroke-like migraine attacks after radiation therapy (SMART)1 and peri-ictal pseudoprogression (PIPG).2
Source: Neurology - September 9, 2013 Category: Neurology Authors: Di Stefano, A. L., Berzero, G., Vitali, P., Galimberti, C. A., Ducray, F., Ceroni, M., Bastianello, S., Colombo, A. A., Simoncelli, A., Brunelli, M. C., Giometto, B., Diamanti, L., Gaviani, P., Salmaggi, A., Silvani, A., Marchioni, E. Tags: All Clinical Neurology, Coma CLINICAL/SCIENTIFIC NOTES Source Type: research

Doses to Carotid Arteries After Modern Radiation Therapy for Hodgkin Lymphoma: Is Stroke Still a Late Effect of Treatment?
Conclusions: INRT reduces the dose delivered to the carotid arteries and corresponding estimated risk of stroke for HL survivors. Even for the subset of patients with lymphoma close to the carotid arteries, the estimated risk is low.
Source: International Journal of Radiation Oncology * Biology * Physics - August 2, 2013 Category: Radiology Authors: Maja V. Maraldo, Patrick Brodin, Marianne C. Aznar, Ivan R. Vogelius, Per Munck af Rosenschöld, Peter M. Petersen, Lena Specht Tags: Lymphomas Source Type: research

Risk of Cerebrovascular Events in Elderly Patients After Radiation Therapy Versus Surgery for Early-Stage Glottic Cancer
Purpose: Comprehensive neck radiation therapy (RT) has been shown to increase cerebrovascular disease (CVD) risk in advanced-stage head-and-neck cancer. We assessed whether more limited neck RT used for early-stage (T1-T2 N0) glottic cancer is associated with increased CVD risk, using the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database.Methods and Materials: We identified patients ≥66 years of age with early-stage glottic laryngeal cancer from SEER diagnosed from 1992 to 2007. Patients treated with combined surgery and RT were excluded. Medicare CPT codes for carotid interventions, Medicare IC...
Source: International Journal of Radiation Oncology * Biology * Physics - July 30, 2013 Category: Radiology Authors: Julian C. Hong, Tim J. Kruser, Vinai Gondi, Pranshu Mohindra, Donald M. Cannon, Paul M. Harari, Søren M. Bentzen Tags: Head and Neck Cancers Source Type: research

Radiation, Atherosclerotic Risk Factors, and Stroke Risk in Survivors of Pediatric Cancer: A Report From the Childhood Cancer Survivor Study
Conclusion: Young adult pediatric cancer survivors have an increased stroke risk that is associated with CRT in a dose-dependent manner. Atherosclerotic risk factors enhanced this risk and should be treated aggressively.
Source: International Journal of Radiation Oncology * Biology * Physics - May 15, 2013 Category: Radiology Authors: Sabine Mueller, Heather J. Fullerton, Kayla Stratton, Wendy Leisenring, Rita E. Weathers, Marilyn Stovall, Gregory T. Armstrong, Robert E. Goldsby, Roger J. Packer, Charles A. Sklar, Daniel C. Bowers, Leslie L. Robison, Kevin R. Krull Tags: Pediatric Cancers Source Type: research

Risk of First and Recurrent Stroke in Childhood Cancer Survivors Treated With Cranial and Cervical Radiation Therapy
Conclusion: Cranial irradiation puts childhood cancer survivors at high risk of both first and recurrent stroke. Stroke prevention strategies for these survivors are needed.
Source: International Journal of Radiation Oncology * Biology * Physics - April 24, 2013 Category: Radiology Authors: Sabine Mueller, Katherine Sear, Nancy K. Hills, Nassim Chettout, Shervin Afghani, Erica Gastelum, Daphne Haas-Kogan, Heather J. Fullerton Tags: Pediatric Cancers Source Type: research