Filtered By:
Specialty: Neurology
Condition: Bleeding
This page shows you your search results in order of date. This is page number 13.
Order by Relevance | Date
Total 720 results found since Jan 2013.
Outcomes and Treatment Complications of Intravenous Urokinase Thrombolysis in Acute Ischemic Stroke in China
Conclusions: Patients treated with urokinase had similar outcomes but a higher risk of extracranial bleeding compared to patients treated with alteplase. The risk of extracranial bleeding was higher in the patients treated with high-dose urokinase than in the patients treated with low-dose urokinase. Patients who received low-dose urokinase had similar outcomes and complications compared to patients treated with alteplase. In countries such as China where some acute ischemic stroke patients cannot afford alteplase, urokinase may be a good alternative to alteplase for intravenous thrombolysis.
Source: Frontiers in Neurology - July 12, 2021 Category: Neurology Source Type: research
Interaction Effect of Baseline Serum Glucose and Early Ischemic Water Uptake on the Risk of Secondary Hemorrhage After Ischemic Stroke
Conclusion: A higher degree of early tissue water uptake and high admission BGL were both independent predictors of ICH. Higher BGL was significantly associated with accelerated effects of NWU on the likelihood of ICH. Although a clear causal relationship remains speculative, stricter BGL control and monitoring may be tested to reduce the risk of ICH in patients undergoing thrombectomy.
Source: Frontiers in Neurology - July 8, 2021 Category: Neurology Source Type: research
Aspirin Use and Risk of Subdural Hematoma: Updated Meta-Analysis of Randomized Trials
Subdural hematomas are an uncommon, but a serious, bleeding complication of antithrombotic therapies. We update our previous inconclusive meta-analysis to better estimate the risk of subdural hematoma associated with aspirin use.
Source: Journal of Stroke and Cerebrovascular Diseases - June 13, 2021 Category: Neurology Authors: Robert G. Hart, Lesly A. Pearce, Philip B. Gorelick, Ben J. Connolly, Luciana Catanese Source Type: research
Safety and Efficacy of Low-Dose Tirofiban Combined With Intravenous Thrombolysis and Mechanical Thrombectomy in Acute Ischemic Stroke: A Matched-Control Analysis From a Nationwide Registry
Conclusion: In acute ischemic stroke patients who underwent mechanical thrombectomy and preceding intravenous thrombolysis, low-dose tirofiban was not associated with increased risk of sICH or ICH. Further randomized clinical trials are needed to confirm the effects of tirofiban in patients undergoing bridging therapy.
Source: Frontiers in Neurology - June 10, 2021 Category: Neurology Source Type: research
Anticoagulation Protocol for Secondary Prevention of Acute Ischemic Stroke Associated with Nonvalvular Atrial Fibrillation
Atrial fibrillation (AF) is a major risk factor for ischemic stroke and despite evidence for the efficacy of anticoagulation for secondary prevention of recurrent stroke in patients with AF,1 to date there is no established evidence regarding the timing for initiation of oral anticoagulants (OACs), including direct oral anticoagulants (DOACs), for secondary prevention of acute ischemic stroke associated with AF. Of concern in early initiation of OACs is the risk of recurrence balanced with the risk of hemorrhagic transformation (HT) after vascular reperfusion with reports of 3.6% symptomatic cerebral bleeding for acute use of OACs.
Source: Journal of Stroke and Cerebrovascular Diseases - June 6, 2021 Category: Neurology Authors: Teruo Kimura, Adam Tucker, Atsushi Nakagaki, Toshihide Sugimura, Shin Fukuda, Makoto Katsuno, Tsutomu Fujita, Naoto Izumi, Nozomi Suzuki, Kazuhiro Sako Source Type: research
Acute T2*-Weighted Magnetic Resonance Imaging Detectable Cerebral Thrombosis in a Rat Model of Subarachnoid Hemorrhage
AbstractSubarachnoid hemorrhage (SAH) is associated with a high incidence of morbidity and mortality, particularly within the first 72 h after aneurysm rupture. We recently found ultra-early cerebral thrombosis, detectable on T2* magnetic resonance imaging (MRI), in a mouse SAH model at 4 h after onset. The current study examined whether such changes also occur in rat at 24 h after SAH, the vessels involved, whether the degree of thrombosis varied with SAH severity and brain injury, and if it differed between male and female rats. Adult Sprague Dawley rats were subjected to an endovascular perforation SAH model or sham...
Source: Translational Stroke Research - June 2, 2021 Category: Neurology Source Type: research
Impact of Platelet Endothelial Aggregation Receptor-1 Genotypes on Long-Term Cerebrovascular Outcomes in Patients With Minor Stroke or Transient Ischemic Attack
Conclusions: Our data do provide robust evidence that genetic variation in PEAR1 rs12041331 do not contribute to atherothrombotic or bleeding risk in minor stroke and TIA patients treated with DAPT.
Source: Frontiers in Neurology - May 28, 2021 Category: Neurology Source Type: research
Non-Vitamin K Antagonist Oral Anticoagulants for the Treatment of Cerebral Venous Sinus Thrombosis: a Retrospective, Matched Cohort Analysis
ConclusionsThe safety and efficacy results of NOAC use for CVT were similar to those for age-matched and sex-matched controls treated with VKAs, as well as historical published controls. Assessment of NOAC efficacy and safety in CVT in multicenter cohort studies and randomized controlled trials is warranted.
Source: Neurocritical Care - May 27, 2021 Category: Neurology Source Type: research
Impact of acetylsalicylic acid (ASA) on postoperative hemorrhage in spinal lumbar surgery: Should preoperative ASA be discontinued for elective surgery?
This study aimed to analyze the risk of bleeding by applying ASA before lumbar spinal surgery.
Source: Journal of the Neurological Sciences - May 22, 2021 Category: Neurology Authors: Ali Rashidi, Fabian Leins, I. Erol Sandalcioglu, Michael Luchtmann Source Type: research
Systemic Inflammation Response Index and Systemic Immune-inflammation Index for Predicting the Prognosis of Patients with Aneurysmal Subarachnoid Hemorrhage
An aneurysmal subarachnoid hemorrhage (aSAH) can result in disability and high mortality.1 Re-bleeding, poor admission neurologic status, thick SAH, vasospasm, and delayed cerebral ischemia (DCI) are known as predicting factors for exacerbated prognosis of aSAH.2 –5 Similar to other cerebrovascular diseases, aSAH can causes a pronounced peripheral inflammatory/immune response. Systemic changes are also associated with outcomes of patients with SAH.6,7 Although the exact mechanism has not yet been fully revealed, inflammation is known to plays an important role in the progress of aSAH by inducing early brain damage, vasos...
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2021 Category: Neurology Authors: Seonyong Yun, Ho Jun Yi, Dong Hoon Lee, Jae Hoon Sung Source Type: research
Safety and efficacy of intravenous thrombolytic treatment in wake ‐up stroke: Experiences from a single center
ConclusionsOur study demonstrated that in patients who awaken with stroke symptoms, intravenous thrombolytic treatment is a safe procedure that may lead to favorable outcomes. Further studies should be performed to increase the size of the group of patients with wake ‐up strokes who can be treated with reperfusion therapy.
Source: Brain and Behavior - May 3, 2021 Category: Neurology Authors: Adam Wi śniewski Tags: ORIGINAL RESEARCH Source Type: research
Risk and prognostic factors in perinatal hemorrhagic stroke
Conclusion: Our findings showed that PHS was much more common in preterm infants. Mucosal bleeding and multiple lobes involvement were more common in term infants. PHS has high morbidity and mortality rates. Small for gestational age and mucosal bleeding were more common in infants who are dead.
Source: Annals of Indian Academy of Neurology - April 28, 2021 Category: Neurology Authors: H ü seyin Ç aksen Fatma Tuba K ö seoglu Ahmet Sami G ü ven H ü seyin Altunhan Mehmet Sinan Iyisoy Saim A ç ikg ö zoglu Source Type: research
The Effect of Aging and Small-Vessel Disease Burden on Hematoma Location in Patients with Acute Intracerebral Hemorrhage
Conclusion: Putaminal, thalamic, and lobar hemorrhages are prone to occur in specific ages and SVD states: putaminal in young patients, thalamic in old and high SVD burden patients, and lobar hemorrhages in old and low SVD burden patients. Susceptibility to bleeding with aging or severe SVD accumulation seems to differ considerably among brain locations.Cerebrovasc Dis
Source: Cerebrovascular Diseases - April 23, 2021 Category: Neurology Source Type: research
A Modified in vitro Clot Lysis Assay Predicts Outcomes in Non-traumatic Intracerebral Hemorrhage Stroke Patients —The IRONHEART Study
Conclusion: Parameters of mCLA correlate with ICH bleeding volume and might be useful to predict ICH outcomes.
Source: Frontiers in Neurology - April 20, 2021 Category: Neurology Source Type: research
An Enriched Environment Leads to Increased Synaptic Plasticity-Associated miRNA Levels after Experimental Subarachnoid Hemorrhage
Subarachnoid hemorrhage is a type of stroke caused by usually bleeding in the subarachnoid space with high morbidity and mortality.1,2 The cause is usually arterial aneurysm rupture and arterial hypertension. SAH also affects cognitive functions. Half of the patients may return to their daily lives in a year after SAH, but most of these patients often have problems in memory, executive functions, and speech functions in the future.3 Although long-term neurological disorders are thought to be caused by late-term cerebral ischemia due to vasospasm triggered by extravascular blood contact with the arteries, the molecular basi...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2021 Category: Neurology Authors: Fulya Buge Ergen, Didem Turgut Cosan, Turan Kandemir, İlknur Dag, Fezan Mutlu, Tevfik Erhan Cosan Source Type: research
