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Specialty: Nuclear Medicine
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Total 204 results found since Jan 2013.
Case report of nuclear medicine, bone scan imaging on a patient with heat stroke induced rhabdomyolysis
J Nucl Med Technol. 2021 Jul 30:jnmt.121.262501. doi: 10.2967/jnmt.121.262501. Online ahead of print.ABSTRACTBone scan continues to be the second greatest-volume nuclear imaging procedure, offering the advantage of total body examination, low cost, and high sensitivity not only for metastatic lesions but also benign conditions. Its power rests in the physiological uptake and pathophysiologic behavior of 99m technetium (99m-Tc) diphosphonates. 1 The localization of radiotracers in damaged skeletal muscles is because calcium builds up in them and provides a site for radiotracer deposition when combined with phosphate.1 In ca...
Source: Journal of Nuclear Medicine Technology - July 31, 2021 Category: Nuclear Medicine Authors: Jitesh Dhingra Yoram Baum Source Type: research
SPECT/CT imaging of inflammation and calcification in human carotid atherosclerosis to identify the plaque at risk of rupture
ConclusionCalcification imaging alone can only accurately identify highly calcified, stable, fibrocalcific plaques. To identify high-risk plaques, with little or no calcification, hybrid imaging of calcification and inflammation could provide diagnostic benefit.
Source: Journal of Nuclear Cardiology - July 27, 2021 Category: Nuclear Medicine Source Type: research
Hemiplegic migraine episode triggered by regadenoson
AbstractSPECT and PET myocardial perfusion imaging (MPI) are widely used to evaluate patients for coronary artery disease. Regadenoson (a selective A2A adenosine receptor agonist) is a commonly used vasodilator agent for stress MPI because of its safety profile and ease of use. Common adverse reactions such as headache, shortness of breath, flushing, and chest and abdominal discomfort are typically mild and can be effectively reversed using methylxanthines such as aminophylline and caffeine. Neurological adverse reactions such as seizure and stroke have rarely been reported with the use of regadenoson. The hemodynamic chan...
Source: Journal of Nuclear Cardiology - July 25, 2021 Category: Nuclear Medicine Source Type: research
Automated radiosynthesis and in vivo PET evaluation of VEGFR2 ligand 11CBTFP
Conclusions: [11C]BTFP, a high affinity and selective VEGFR2 ligand amenable for radiolabeling with [11C]isotope, is synthesized and radiolabeled. microPET imaging studies exhibit BBB penetration and retention of [11C]BTFP in mice brain. The details of radiosynthesis and imaging experiments will be presented. References: (1) Shim, J.W.; Madsen, J.R. VEGF Signaling in Neurological Disorders. Int. J. Mol. Sci. 2018, 19(1): 275. (2) Apte RS, Chen DS, Ferrara N. VEGF in Signaling and Disease: Beyond Discovery and Development. Cell. 2019, 176(6):1248.
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Neelamegam, R., Kumar, D. Tags: Automation & amp; Technology Development Source Type: research
Two-year change in 18F-sodium fluoride uptake in the carotid arteries of healthy subjects and angina pectoris patients
Conclusions: Slightly higher NaF uptake in the angina group indicated more ongoing carotid microcalcification at both time points in patients than in healthy subjects. The 2-year changes were very small in both groups, albeit with a tendency of slight decreases among healthy controls, suggesting a more dynamic, waxing and waning, process in these compared to a slow, but more consistent, progression in angina patients despite statin therapy in half of these.
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Piri, R., Lici, G., Riyahimanesh, P., Gerke, O., Alavi, A., Flemming Hoilund-Carlsen, P. Tags: Clinical Science Source Type: research
Conventional and molecular imaging in sickle cell disease
Conclusions: Central nervous system: About 25% of SCD patients are affected by vascular involvement of central nervous system. CT scan has been used to detect cerebral infarction. Subclinical cranial MRI lesions yield important predictive values as a risk factor of stroke, even when detected in asymptomatic patients. SPECT is a useful technique for early detection of deficits in cerebral perfusion in patients with SCD. Decreases in cerebral perfusions may lead to silent infarction, stroke, or neurocognitive diseases. PET may improve sensitivity in detection of impaired metabolism in the area surrounding a major vessel infa...
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Taghvaei, R., Sirous, R., Raynor, W., Amanullah, A., Werner, T., Revheim, M.-E., Hoilund-Carlsen, P. F., Alavi, A. Tags: General Clinical Specialties Source Type: research
Brain-related complications of COVID-19 and the role of FDG-PET in detecting vascular and non-vascular defects throughout the body
Conclusions FDG-PET can characterize the extent of systemic disease in COVID-19 patients and provide value in the early identification of complications that may make patients more susceptible to the harmful respiratory and systemic side effects of COVID-19. Severe neurological ramifications of COVID-19 have been noted such as the increased prevalence of acute cerebrovascular incidents. In these contexts, emerging literature has proven that the use of FDG-PET can be useful in monitoring the neurological manifestations the COVID-19 virus.
Source: Journal of Nuclear Medicine - May 18, 2021 Category: Nuclear Medicine Authors: Rigney, G., Ayubcha, C., Werner, T., Revheim, M.-E., Alavi, A. Tags: Neurosciences Source Type: research
Crossed cerebellar diaschisis: risk factors and prognostic value in focal cortical dysplasia by 18 F-FDG PET/CT
ConclusionThe number of lobes involved on PET, structural anomalies on MRI, the |AI| values in the posterior frontal and anterior temporal lobes may be predisposing factors for CCD. CCD occurrence may help predict the prognosis of FCD patients at 12 months postoperatively.
Source: Annals of Nuclear Medicine - April 11, 2021 Category: Nuclear Medicine Source Type: research
Imaging of the glioma microenvironment by TSPO PET
AbstractGliomas are highly dynamic and heterogeneous tumours of the central nervous system (CNS). They constitute the most common neoplasm of the CNS and the second most common cause of death from intracranial disease after stroke. The advances in detailing the genetic profile of paediatric and adult gliomas along with the progress in MRI and PET multimodal molecular imaging technologies have greatly improved prognostic stratification of patients with glioma and informed on treatment decisions. Amino acid PET has already gained broad clinical application in the study of gliomas. PET imaging targeting the translocator prote...
Source: European Journal of Nuclear Medicine and Molecular Imaging - March 15, 2021 Category: Nuclear Medicine Source Type: research
Multi-scale optoacoustic molecular imaging of brain diseases
We describe outstanding challenges in optoacoustic imaging methodologies and propose a future outlook.
Source: European Journal of Nuclear Medicine and Molecular Imaging - February 16, 2021 Category: Nuclear Medicine Source Type: research
