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Specialty: Neuroscience
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Total 6766 results found since Jan 2013.
Sodium Tanshinone IIA Sulfonate Ameliorates Oxygen-glucose Deprivation/Reoxygenation-induced Neuronal Injury via Protection of Mitochondria and Promotion of Autophagy
Neurochem Res. 2023 Jul 12. doi: 10.1007/s11064-023-03985-x. Online ahead of print.ABSTRACTSodium tanshinone IIA sulfonate (STS) has shown significant clinical therapeutic effects in cerebral ischemic stroke (CIS), but the molecular mechanisms of neuroprotection remain partially known. The purpose of this study was to explore whether STS plays a protective role in oxygen-glucose deprivation/reoxygenation (OGD/R)-induced neuronal injury by regulating microglia autophagy and inflammatory activity. Co-cultured microglia and neurons were subjected to OGD/R injury, an in vitro model of ischemia/reperfusion (I/R) injury with or ...
Source: Neurochemical Research - July 12, 2023 Category: Neuroscience Authors: Zhi Ma Yue Wu Juan Xu Hui Cao Mingyang Du Haibo Jiang Feng Qiu Source Type: research
Hypoxic postconditioning drives protective microglial responses and ameliorates white matter injury after ischemic stroke
CONCLUSION: HPC promotes protective microglial responses and white matter repair after MCAO, which may be related to the proliferation and differentiation of oligodendrocytes.PMID:37435771 | DOI:10.1111/cns.14346
Source: CNS Neuroscience and Therapeutics - July 12, 2023 Category: Neuroscience Authors: Wei Zhang Sijie Li Ho Jun Yun Wantong Yu Wenjie Shi Chen Gao Jun Xu Yu Yang Linhui Qin Yuchuan Ding Kunlin Jin Fengyong Liu Xunming Ji Changhong Ren Source Type: research
Neurofeedback therapy to improve cognitive function in patients with chronic post-stroke attention deficits: a within-subjects comparison
This study is the first attempt to train patients who survived stroke with SCP neurofeedback therapy.MethodsWe included N = 5 participants in a within-subjects follow-up design. We assessed neuropsychological and psychological performance at baseline (4 weeks before study onset), before study onset, after neurofeedback training, and at 3 months follow-up. Participants underwent 20 sessions of SCP neurofeedback training.ResultsParticipants learned to regulate SCPs toward negativity, and we found indications for improved attention after the SCP neurofeedback therapy in some participants. Quality of life improved throughout t...
Source: Frontiers in Human Neuroscience - July 11, 2023 Category: Neuroscience Source Type: research
Muscle Synergy-Based Functional Electrical Stimulation Reduces Muscular Fatigue in Post-Stroke Patients: A Systematic Comparison
Muscle synergy-based functional electrical stimulation had improved movement kinematics instantly and in long-term use in post-stroke patients. However, the therapeutic benefits and efficacy of muscle synergy-based functional electrical stimulation patterns over traditional stimulation patterns need exploration. This paper presents the therapeutic benefits of muscle synergy-based functional electrical stimulation compared to traditional stimulation patterns from the perspective of muscular fatigue and kinematic performance produced. Three stimulation waveforms/envelopes: customized rectangular, trapezoidal, and muscle syne...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - July 7, 2023 Category: Neuroscience Source Type: research
Preface: Special issue “”
The special issue “Brain Proteostasis in Health and Disease” features both original and review articles written by specialists in the field of protein homeostasis. Deregulation of adequate proteostasis may contribute to brain diseases, including several neuropsychiatric and neurodegenerative conditions. Therefore , delineating the processes underlying protein synthesis, folding, stability, function, and degradation in brain cells is key to promoting brain function and identifying effective therapeutic options for neurological disorders. This special issue covers the roles of protein homeostasis in several me chanisms t...
Source: Journal of Neurochemistry - July 7, 2023 Category: Neuroscience Authors: Mychael V. Lourenco Tags: EDITORIAL Source Type: research
Connection between oxidative stress and subcellular organelle in subarachnoid hemorrhage: Novel mechanisms and therapeutic implications
CNS Neurosci Ther. 2023 Jul 5. doi: 10.1111/cns.14348. Online ahead of print.ABSTRACTSpontaneous subarachnoid hemorrhage (SAH) is one of the most devastating forms of stroke, with limited treatment modalities and poor patient outcomes. Previous studies have proposed multiple prognostic factors; however, relative research on treatment has not yet yielded favorable clinical outcomes. Moreover, recent studies have suggested that early brain injury (EBI) occurring within 72 h after SAH may contribute to its poor clinical outcomes. Oxidative stress is recognized as one of the main mechanisms of EBI, which causes damage to vario...
Source: CNS Neuroscience and Therapeutics - July 6, 2023 Category: Neuroscience Authors: Jiahao Zhang Zeyu Zhang Xiaoyu Wang Yibo Liu Qian Yu Kaikai Wang Yuanjian Fang Cameron Lenahan Maohua Chen Sheng Chen Source Type: research
The Neurophysiological Features Associated with Unilateral Spatial Neglect Recovery: A Scoping Review
Brain Topogr. 2023 Jul 6. doi: 10.1007/s10548-023-00980-x. Online ahead of print.ABSTRACTThe purpose of this scoping review is to provide updated information on the neural basis and neurophysiological features associated with unilateral spatial neglect (USN) recovery. We applied the Preferred Reporting Systems for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) framework and identified 16 relevant papers from the databases. Critical appraisal was performed by two independent reviewers using a standardized appraisal instrument developed by the PRISMA-ScR. We identified and categorized investi...
Source: Brain Topography - July 6, 2023 Category: Neuroscience Authors: Masaya Ueda Takuma Yuri Keita Ueno Ryouhei Ishii Yasuo Naito Source Type: research
Preface: Special issue “Brain Proteostasis in Health and Disease”
The special issue “Brain Proteostasis in Health and Disease” features both original and review articles written by specialists in the field of protein homeostasis. Deregulation of adequate proteostasis may contribute to brain diseases, including several neuropsychiatric and neurodegenerative conditions. Therefore , delineating the processes underlying protein synthesis, folding, stability, function, and degradation in brain cells is key to promoting brain function and identifying effective therapeutic options for neurological disorders. This special issue covers the roles of protein homeostasis in several me chanisms t...
Source: Journal of Neurochemistry - July 6, 2023 Category: Neuroscience Authors: Mychael V. Lourenco Tags: EDITORIAL Source Type: research
Hand-worn devices for assessment and rehabilitation of motor function and their potential use in BCI protocols: a review
DiscussionWe conclude that hand-worn devices that monitor both flexion and grip will benefit both clinical diagnostic assessment of function during treatment and closed-loop BCI protocols aimed at rehabilitation.
Source: Frontiers in Human Neuroscience - July 6, 2023 Category: Neuroscience Source Type: research
