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Condition: Thrombosis
Procedure: Coronary Artery Bypass Graft

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Total 89 results found since Jan 2013.

Stroke in Patients With Aortic Stenosis: The Simvastatin and Ezetimibe in Aortic Stenosis Study Clinical Sciences
Conclusions— In patients with aortic stenosis not prescribed oral anticoagulation, atrial fibrillation, AVR with concomitant coronary artery bypass grafting, and CHA2DS2-VASc score were the major predictors of stroke. Incident stroke was strongly associated with mortality. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00092677.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Greve, A. M., Dalsgaard, M., Bang, C. N., Egstrup, K., Ray, S., Boman, K., Rossebo, A. B., Gohlke-Baerwolf, C., Devereux, R. B., Kober, L., Wachtell, K. Tags: Thrombosis risk factors, CV surgery: valvular disease, Acute Cerebral Infarction Clinical Sciences Source Type: research

Left Atrial Appendage Closure: Is the Strategy Enough to Lower Long-Term Stroke Risk?
AbstractPurpose of ReviewLeft atrial appendage closure (LAAC) emerged as a promising site-directed therapy to mitigate stroke risk in patients ineligible for long-term oral anticoagulation. We sought to summarize the current evidence regarding the role of LAAC on long-term risk of ischemic stroke and systemic thromboembolism.Recent FindingsData from EWOLUTION registry provides real world evidence on the 1-year outcomes of LAAC by WATCHMAN device. The annual ischemic stroke rate was 1.1 per 100 patient-years, as opposed to the CHADS2VASC score-predicted stroke rate of 7.2% (84% relative risk reduction). No differences in de...
Source: Current Cardiovascular Risk Reports - August 19, 2017 Category: Cardiology Source Type: research

Circulating microaggregates during cardiac surgery precedes postoperative stroke
This report presents intraoperative microcirculation-based evidence suggesting that observations of microaggregations, otherwise undetected by conventional anticoagulation assessment techniques, could serve as an early warning in elderly patients at high risk for postoperative cerebrovascular events.
Source: Journal of Thrombosis and Thrombolysis - May 22, 2017 Category: Hematology Source Type: research

Paradoxical Emboli as a Cause of Stroke
We present two cases of PDE resulting in acute ischemic events. A 63-year-old female presented for evaluation of left upper extremity numbness. Imaging was significant for an acute right middle cerebral artery infarct and evidence of a large saddle pulmonary embolism. The patient's stroke was postulated to have been secondary to a patent foramen ovale (PFO). An 87-year-old male presented for evaluation of chest pain. The patient underwent three-vessel CABG and experienced an acute left hemispheric stroke post-operatively. Transthoracic echocardiogram demonstrated a biatrial thrombus transversing a PFO and was postulated to...
Source: The American Surgeon - February 28, 2023 Category: Surgery Authors: Ilya Sakharuk Peter Drevets Philip Coffey Wasef Nijim Vijay Patel Source Type: research

Anticoagulation for stroke prevention in new atrial fibrillation after coronary artery bypass graft surgery
The benefit of early anticoagulation for stroke prophylaxis in atrial fibrillation after coronary artery bypass graft (CABG) surgery is uncertain. We therefore studied what proportion of ischemic strokes in patients with atrial fibrillation early after CABG surgery were potentially preventable by anticoagulation with warfarin.
Source: Thrombosis Research - February 24, 2015 Category: Hematology Authors: S. Schulman, I. Cybulsky, J. Delaney Tags: Regular Article Source Type: research

Rivaroxaban: an oral factor xa inhibitor.
CONCLUSIONS: Based on the findings of the studies reported in this review, rivaroxaban is an effective option for the prevention of VTE after orthopedic surgery, stroke prevention for nonvalvular AF, and treatment of VTE. At this time, rivaroxaban cannot be recommended for secondary risk reduction after ACS because of the increased bleeding risk. PMID: 23328267 [PubMed - in process]
Source: Clinical Therapeutics - January 1, 2013 Category: Drugs & Pharmacology Authors: Thomas TF, Ganetsky V, Spinler SA Tags: Clin Ther Source Type: research

Should TCDs be routinely used for evaluating intracranial circulation for screening high risk patients prior to cardiac surgery? (P2.280)
CONCLUSIONS: Our case elucidates the possibility of a hypoperfusion stroke related to left vertebral dominantly supplying intracranial circulation in presence of bilateral significant carotid stenosis. Due to lack of previous cardio/cerebrovascular events, his carotid stenosis was deemed asymptomatic prior to cardiac surgery. We propose that intracranial collateral flow should be investigated via TCD in patients with bilateral carotid stenosis undergoing procedures with high stroke risk to assess safety and efficacy of carotid revascularization in this small but significant subset. Additional studies like acetazolamide wit...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Vu, Q., Bishop, L., Edwards, M., Tegeler, C., Sarwal, A. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research

Free-floating left atrial ball thrombus after mitral valve replacement with patent coronary artery bypass grafts: successful removal by a right minithoracotomy approach without aortic cross-clamp
We describe a case in a 79-year-old woman with chronic atrial fibrillation and a recent stroke who had undergone mitral valve replacement 25 years previously and coronary artery bypass grafting 5 years previously. Redo cardiac surgery represents a clinical challenge due to a higher rate of peri-operative morbidity and mortality. Median re-sternotomy can be particularly difficult in patients with functioning coronary artery grafts, where the risk of graft injury is a significant concern. Prompt surgical intervention was carried out, and to avoid the challenge of re-sternotomy in this patient with two prior thoracotomies, ...
Source: General Thoracic and Cardiovascular Surgery - May 22, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Percutaneous coronary intervention or coronary artery bypass grafting for unprotected left main coronary artery disease
ConclusionsIn patients with unprotected left main coronary disease and low to intermediate SYNTAX score, PCI might be an acceptable alternative to CABG. © 2017 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - March 14, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Ahmed N. Mahmoud, Islam Y. Elgendy, Amgad Mentias, Marwan Saad, Walid Ibrahim, Mohammad K. Mojadidi, Ramez Nairooz, Parham Eshtehardi, R. David Anderson, Habib Samady Tags: Coronary Artery Disease Source Type: research

Prospective Study on the Incidence of Cerebrovascular Disease After Coronary Angiography.
CONCLUSIONS: We suggested that the incidence of cerebral infarction after CAG was not related to the catheterization procedure per se but may be caused by atherosclerosis with CABG. PMID: 28855432 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - September 2, 2017 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Drug-eluting stents in elderly patients with coronary artery disease (SENIOR): a randomised single-blind trial
Publication date: Available online 1 November 2017 Source:The Lancet Author(s): Olivier Varenne, Stéphane Cook, Georgios Sideris, Sasko Kedev, Thomas Cuisset, Didier Carrié, Thomas Hovasse, Philippe Garot, Rami El Mahmoud, Christian Spaulding, Gérard Helft, José F Diaz Fernandez, Salvatore Brugaletta, Eduardo Pinar-Bermudez, Josepa Mauri Ferre, Philippe Commeau, Emmanuel Teiger, Kris Bogaerts, Manel Sabate, Marie-Claude Morice, Peter R Sinnaeve Background Elderly patients regularly receive bare-metal stents (BMS) instead of drug-eluting stents (DES) to shorten the duration of double antiplatelet therapy (DAPT). The ai...
Source: The Lancet - November 2, 2017 Category: General Medicine Source Type: research

Abstract 250: Economic Burden of Mortality and Cardiovascular Events among Patients with Acute Coronary Syndromes in a Commercial Health Plan Poster Session III
Conclusion: Our findings suggest that a modest 10% increase in anticoagulant use among patients with ACS would reduce mortality, MI, ST and related healthcare costs by 4%, 0.7%, and 3%, respectively. Addition of anticoagulation therapy potentially reduces the incidence of ACS-related mortality, MI, ST and associated healthcare costs to a commercial health plan, and benefits from anticoagulation use should be balanced against the risk of bleeding.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Ogden, K., Patel, A. A., Mody, S. H., Veerman, M., Crivera, C., Quock, T. P. Tags: Poster Session III Source Type: research

Angiographic success and procedural complications in patients undergoing retrograde percutaneous coronary chronic total occlusion interventions: A weighted meta-analysis of 3482 patients from 26 studies
Conclusions: Retrograde CTO PCI is associated with high procedural success rate and acceptable risk for procedural complications.
Source: International Journal of Cardiology - April 25, 2014 Category: Cardiology Authors: Abdallah El Sabbagh, Vishal G. Patel, Omar M. Jeroudi, Tesfaldet T. Michael, Mohammed E. Alomar, Owen Mogabgab, Eric Fuh, Michele Roesle, Bavana V. Rangan, Shuaib Abdullah, Jeffrey L. Hastings, Jerrold Grodin, Dharam J. Kumbhani, Dimitrios Alexopoulos, Pa Tags: Reviews Source Type: research

Five-year outcomes of staged percutaneous coronary intervention in the SYNTAX study.
CONCLUSIONS: There is a higher incidence of MACCE in patients undergoing staged compared to single-session PCI for 3-vessel and/or left main disease over the first five years of follow-up. However, these patients had more comorbidities and more diffuse disease. PMID: 25912390 [PubMed - in process]
Source: EuroIntervention - May 1, 2015 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Influence of Gender on Long-Term Outcomes After Implantation of Bare-Metal Stent: A Multicenter Report From the Coronary Revascularization Demonstrating Outcome Study-Kyoto (CREDO-Kyoto) Registry Cohort-1.
CONCLUSIONS: -TLR and ST continued to occur without attenuation up to 10-year after BMS implantation. Men as compared with women were associated with higher adjusted 10-year risks for all-cause death, MI, stroke, CABG, TLR, and non-TLR. PMID: 26443611 [PubMed - as supplied by publisher]
Source: Circulation - October 6, 2015 Category: Cardiology Authors: Yamaji K, Shiomi H, Morimoto T, Toyota T, Ono K, Furukawa Y, Nakagawa Y, Kadota K, Ando K, Shirai S, Kato M, Takatsu Y, Doi O, Kambara H, Suwa S, Onodera T, Watanabe H, Natsuaki M, Kimura T Tags: Circulation Source Type: research