Outcomes by sex in the International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) trial
CONCLUSIONS: In ISCHEMIA, women assigned to the INV arm were less likely to undergo revascularisation than men. The effect of an INV versus CON strategy was consistent by sex, but women had a significantly lower contribution of procedural MI to the primary outcome.PMID:38444364 | DOI:10.4244/EIJ-D-24-00011 (Source: EuroIntervention)
Source: EuroIntervention - March 6, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Mario Gaudino John H Alexander Sigrid Sandner Lamia Harik Jessica Kim Gregg W Stone Mohamed Rahouma Patrick O'Gara Deepak L Bhatt Bjorn Redfors Source Type: research

One-month DAPT with ticagrelor and aspirin for patients undergoing coronary artery bypass grafting: rationale and design of the randomised, multicentre, double-blind, placebo-controlled ODIN trial
EuroIntervention. 2024 Mar 4;20(5):e322-e328. doi: 10.4244/EIJ-D-23-00699.ABSTRACTThe optimal antiplatelet strategy after coronary artery bypass graft (CABG) surgery in patients with chronic coronary syndromes (CCS) is unclear. Adding the P2Y12 inhibitor, ticagrelor, to low-dose aspirin for 1 year is associated with a reduction in graft failure, particularly saphenous vein grafts, at the expense of an increased risk of clinically important bleeding. As the risk of thrombotic graft failure and ischaemic events is highest early after CABG surgery, a better risk-to-benefit profile may be attained with short-term dual antiplat...
Source: EuroIntervention - March 4, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Sigrid Sandner Mario Gaudino Bjorn Redfors Dominick J Angiolillo Ori Ben-Yehuda Deepak L Bhatt Stephen E Fremes Andre Lamy Riccardo Marano Roxana Mehran Stuart Pocock Sunil V Rao John A Spertus Jonathan W Weinsaft George Wells Marc Ruel Source Type: research

Acute changes in microvascular resistance after treating aortic stenosis
EuroIntervention. 2024 Mar 4;20(5):e274-e275. doi: 10.4244/EIJ-E-23-00068.NO ABSTRACTPMID:38436366 | PMC:PMC10905189 | DOI:10.4244/EIJ-E-23-00068 (Source: EuroIntervention)
Source: EuroIntervention - March 4, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Nils P Johnson Rob Eerdekens Source Type: research

Single antiplatelet therapy following Amplatzer left atrial appendage occlusion
CONCLUSIONS: SAPT following Amplatzer LAAO displayed rates of DRT and stroke comparable to those reported with more intensive antithrombotic regimens. Meanwhile, we observed low rates of major bleeding.PMID:38436367 | PMC:PMC10905198 | DOI:10.4244/EIJ-D-23-00684 (Source: EuroIntervention)
Source: EuroIntervention - March 4, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Anders Kramer Kasper Korsholm Jens Erik Nielsen-Kudsk Source Type: research

Early outcomes of transapical mitral valve implantation versus surgical replacement in matched elderly patients at intermediate surgical risk
CONCLUSIONS: Patients with intermediate surgical risk, according to STS-PROM and EuroSCORE II, demonstrated higher rates of MVARC device at 30 days after TMVI compared to 30 days after SMVR. Rates of survival and procedural success, neurological, renal and bleeding complications were similar. Transfusion count and length of stay were lower after TMVI. For elderly patients at intermediate risk, a TMVI eligibility assessment may be considered.PMID:38436368 | PMC:PMC10905192 | DOI:10.4244/EIJ-D-23-00734 (Source: EuroIntervention)
Source: EuroIntervention - March 4, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Johannes A Ziegelmueller Melchior Burri Andreas Stein Peter Tassani-Prell Markus Krane R üdiger Lange Hendrik Ruge Source Type: research

Angiography ‑based quantitative flow ratio for functional assessment of intracranial atherosclerotic disease
CONCLUSIONS: The μQFR was significantly associated with symptomatic ICAS and outperformed the angiographic stenosis severity. The final nomogram effectively discriminated symptomatic lesions and may provide a useful tool for risk stratification in ICAS patients.PMID:38436369 | PMC:PMC10905197 | DOI:10.4244/EIJ-D-23-00611 (Source: EuroIntervention)
Source: EuroIntervention - March 4, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Kangmo Huang Haotao Li Shengxian Tu Juan Du Weihe Yao Rui Liu Yunfei Han Ruidong Ye Shiteng Suo Wusheng Zhu Xinfeng Liu Source Type: research

Impact of percutaneous mitral paravalvular leak closure on the natural history of recurrent gastrointestinal bleeding
EuroIntervention. 2024 Mar 4;20(5):e329-e331. doi: 10.4244/EIJ-D-23-00703.NO ABSTRACTPMID:38436370 | PMC:PMC10905193 | DOI:10.4244/EIJ-D-23-00703 (Source: EuroIntervention)
Source: EuroIntervention - March 4, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Yassin Belahnech Bruno Garc ía Del Blanco Ignacio Ferreira-Gonz ález Eduard R ódenas-Alesina Carmen Alonso-Cotoner Laura Galian-Gay Mar ía Bermudez-Ramos Rosa Vila-Olives Gerard Mart í-Aguasca Source Type: research

Navigating the complexities of antithrombotic therapy after LAAO
EuroIntervention. 2024 Mar 4;20(5):e276-e277. doi: 10.4244/EIJ-E-24-00001.NO ABSTRACTPMID:38436371 | PMC:PMC10905190 | DOI:10.4244/EIJ-E-24-00001 (Source: EuroIntervention)
Source: EuroIntervention - March 4, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Mohamad Alkhouli Source Type: research