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Relationship between coronary diastolic pressure indexes during the wave ‐free period and a novel pressure‐derived index: Diastolic pressure ratio at the optimal point
ConclusionsA simple pressure ‐derived physiological marker of coronary stenosis, DROP, might represent other diastolic pressure indexes with a numerical equivalency to the instantaneous wave‐free ratio. DROP can be measured automatically assuming that the rising points on the aortic pressure curve are detectable. However, f urther large‐scale clinical investigations are needed to determine whether DROP could contribute to the further generalization of physiology‐guided percutaneous coronary intervention. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 27, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Fumiaki Nakao, Yasuhiro Ikeda, Takamasa Oda, Tooru Ueda, Takeshi Ueyama, Takashi Fujii Tags: CORONARY ARTERY DISEASE Source Type: research

Issue Information ‐ TOC
Catheterization and Cardiovascular Interventions, Volume 92, Issue 6, Page v-viii, November 15, 2018. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Tags: Issue Information ‐ TOC Source Type: research

Issue Information ‐ Copyright
Catheterization and Cardiovascular Interventions, Volume 92, Issue 6, Page i-i, November 15, 2018. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Tags: Issue Information ‐ Copyright Source Type: research

Issue Information ‐ Editorial Board
Catheterization and Cardiovascular Interventions, Volume 92, Issue 6, Page iii-iii, November 15, 2018. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Tags: Issue Information ‐ Editorial Board Source Type: research

BioResorbable scaffolds: Out of sight but not out of mind
Key Points The article highlights the results of a new novel BioResorbable Scaffold in “real world” practice Based on this, further design iterations could be reviewed for next generation BRS Larger and longer‐term trials would be needed to define the safety and effectiveness of new BRS in daily clinical practice (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Ashok Seth, Vishal Rastogi Tags: Coronary Artery Disease Source Type: research

Is the local guy, just a local guy?
Key Points The most important risk factors and preventive strategies for coronary atherosclerosis are systemic. However, the clinical manifestations of atherosclerotic disease frequently resemble a localized process, instead of a systemic one. In this issue of CCI, Zhang and co ‐workers described the association between the occurrence of stent failure and the changes in the 3D geometry of coronary segments induced by stent implantation. The investigation of local modulators of coronary disease appears as a large and fertile field of future cardiovascular research. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Pedro A. Lemos Tags: Coronary Artery Disease Source Type: research

When small vessels become big problems! Microvascular dysfunction in NSTEMI
Key Points In a carefully selected cohort of 83 NSTEMI patients, there was a wide variation in the index of microcirculatory resistance (IMR) Elevated IMR, which correlates with microvascular obstruction by MRI, was an independent predictor of adverse cardiovascular outcomes in patients with NSTEMI Further investigation is warranted to understand the influence of the microvascular on prognosis following myocardial infarction (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Elizabeth P Held, Timothy D. Henry Tags: Coronary Artery Disease Source Type: research

Day ‐after PCI: Safe for the patient but perhaps not for the Interventionalist
This study generally confirms the results of a previous single center study and another study using the NCDR CathPCI Registry. This study suggests that day‐after PCI is generally safe, but it behooves cath lab managers and interventionalists to take simple steps to minimize the risk to patients when da y‐after PCIs are performed. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: James C. Blankenship Tags: Coronary Artery Disease Source Type: research

Embolic stroke of undetermined source and patent foramen ovale closure: Practice insights from meta ‐analysis?
Key Points Closure of patent foramen ovale (PFO) in embolic stroke of undetermined source (ESUS) reduces recurrent stroke compared with antiplatelet therapy in select patients but increases risk of atrial fibrillation. Device closure is an attractive option for young patients with an anatomically higher risk PFO and imaging proven ESUS. Benefit of PFO closure in ESUS compared with oral anticoagulation remains undefined. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Arka Chatterjee, William B. Hillegass Tags: Valvular and Structural Heart Diseases Source Type: research

Which embolic protection device is ideal during carotid artery stenting?
Key Points Embolic stroke is one of the main risks of carotid artery stenting. The EMBOLDEN trial demonstrates the safety and efficacy of the Gore ® embolic filter. There is no clear evidence for the benefit of one filter‐type over another. It is important to choose the device with which the interventionalist has significant familiarity. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Nachiket J. Patel, Richard R. Heuser Tags: Peripheral Vascular Disease Source Type: research

Unstable presentation: One Stent trumps two
This report was a retrospective look at a large registry database. A one ‐stent strategy trumps a two‐stent approach in patients with acute coronary syndromes in this large registry. The primary endpoint and target lesion revascularization was half the rate if a one‐stent strategy was used. The incidence of stent thrombosis was more than three‐fold as high using a planned two‐stent strategy. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Samuel Butman Tags: Coronary Artery Disease Source Type: research

Non ‐femoral TAVR: Time to stratify alternative vascular approaches
Key Points Although transfemoral transcatheter aortic valve replacement (TAVR) is the gold standard, this approach is not be feasible in approximately 15% of the patients. Trans ‐carotid TAVR may be less invasive than transthoracic routes for TAVR, and has been associated with encouraging results. Further prospective studies comparing alternative access routes in patients with whom transfemoral TAVR is not feasible are warranted, to propose an evidence‐based algorithm g uiding the physician decision. (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Paul Guedeney, Roxana Mehran Tags: Valvular and Structural Heart Diseases Source Type: research

Caution! You're approaching a gray zone: FFR outcomes and the role of CFR and IMR
This study demonstrates that compared with low ‐ fractional flow reserve (FFR) lesions (<0.75), those in the gray ‐zone FFR (0.75–0.80) are less likely to have improvement or more likely to have impairment in flow after percutaneous coronary intervention. The findings suggest index of microcirculatory resistance measurement may help identify lesions in the FFR gray zone that are most likely to improve. The study reinforces that FFR measurements represent a continuum of ischemic values and that a single dichotomous threshold oversimplifies the answer to whether a lesion should be revascularized. (Source: Catheteriz...
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Morton J. Kern, Arnold H. Seto Tags: Coronary Artery Disease Source Type: research

Septal rupture closure: Still a challenge
Key Points Review of the Medicare database shows that over the past 16  years the incidence of post‐ myocardial infarction (MI) ventricular septal rupture (VSR) has decreased but mortality for all post‐MI VSR hospitalizations remains unchanged and high During the study period, the 30‐day VSR repair rate decreased from 49.9% in 1999 to 33.3% in 2014. Unadjusted mortality was lower for patients undergoing repair procedures than for those not undergoing repair both at 30 days and at 1‐year. Most VSR patients underwent surgical repair (82.9%) and only a minority underwent transcatheter repair (17.1%). Regardless of...
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Norihiko Kamioka, Peter C. Block Tags: Coronary Artery Disease Source Type: research

Predicting the unpredictable mortality outcome of valve ‐in‐valve interventions
Key Points Surgical aortic valve replacement (AVR) risk scores overestimate valve ‐in‐valve (ViV) transcatheter AVR (TAVR) mortality, with moderate discrimination Due to low prevalence of 30‐day mortality, positive predictive value is low Specific risk score examining multiple outcomes for TAVR and ViV patients are needed (Source: Catheterization and Cardiovascular Interventions)
Source: Catheterization and Cardiovascular Interventions - November 26, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Ran Kornowski, Oren Zusman Tags: Valvular and Structural Heart Diseases Source Type: research