Filtered By:
Specialty: Biology
This page shows you your search results in order of relevance. This is page number 8.
Order by Relevance | Date
Total 656 results found since Jan 2013.
Diffusional Characteristics of Brain Matter after Stroke
We analyzed characteristics of diffusion and its kurtosis obtained using diffusion-kurtosis MRI in the hemisphere contralateral to the one affected by acute cerebrovascular accident. Diffusion characteristics in the white and gray matter were compared using analysis of covariance (ANCOVA) in healthy subjects and stroke patients with consideration for the age and sex factors. Significant differences between the groups were revealed for apparent diffusion coefficient and mean kurtosis in the white matter. Age dependence was studied using regression analysis and, according to the results of ANCOVA, this factor was found to be...
Source: Bulletin of Experimental Biology and Medicine - February 17, 2022 Category: Biology Source Type: research
A Canine Surgical Model of Stroke by Minimally Invasive Occlusion of the Proximal Middle Cerebral Artery
In this study, a model of ischemic stroke by surgical proximal middle cerebral artery (MCA) occlusion was developed on 10 beagle dogs. The advantages of this model are the transtemporal approach and a minimally invasive surgical procedure. Dogs were randomly assigned to two groups: sham-operated (proximal MCA exposure without occlusion) and experimental (permanent proximal MCA occlusion) groups. Different evaluation methods were used to assess the consequences of MCA occlusion in dogs, including neurobehavioral tests, MRI, and immunohistochemical staining. Clear signs of cerebral infarction associated with the region suppl...
Source: Bulletin of Experimental Biology and Medicine - February 3, 2023 Category: Biology Source Type: research
Identification of three potential novel biomarkers for early diagnosis of acute ischemic stroke via plasma lipidomics
ConclusionsOur work provides valuable information on the pathophysiology of AIS and constitutes an important step toward clinical application of blood-based biomarkers for diagnosing AIS.
Source: Metabolomics - March 30, 2023 Category: Biology Source Type: research
NR4A1 destabilizes < i > TNF < /i > mRNA in microglia and modulates stroke outcomes
by Yao Yao
Microglia play a dual role in stroke depending on their pro-inflammatory and anti-inflammatory polarization. A study in PLOS Biology identifies a new mechanism, through which the transcription factor NR4A1 negatively regulates TNF expression in microglia.
Microglia play a dual role in stroke depending on their pro-inflammatory and anti-inflammatory polarization. This Primer explores a PLOS Biology study that identifies a new mechanism through which the transcription factor NR4A1 negatively regulates TNF expression in microglia.
Source: PLoS Biology: Archived Table of Contents - July 25, 2023 Category: Biology Authors: Yao Yao Source Type: research
Novel nanotherapy breakthrough may help reduce recurrent heart attacks and stroke
(The Mount Sinai Hospital / Mount Sinai School of Medicine) New report in Nature Communications by Icahn School of Medicine at Mount Sinai shows their new statin nanotherapy can target high-risk inflammation inside heart arteries that causes heart attacks or stroke.
Source: EurekAlert! - Biology - January 20, 2014 Category: Biology Source Type: news
Can citrus ward off your risk of stroke?
(American Academy of Neurology) Eating foods that contain vitamin C may reduce your risk of the most common type of hemorrhagic stroke, according to a study released today that will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26-May 3, 2014.
Source: EurekAlert! - Biology - February 14, 2014 Category: Biology Source Type: news
Complex brain functional network connection after stroke
(Neural Regeneration Research) A research team from Huazhong University of Science and Technology in China inferred that these models could also be used to explore functional network connectivity changes in stroke patients.
Source: EurekAlert! - Biology - March 24, 2014 Category: Biology Source Type: news
New ultrasound device may add in detecting risk for heart attack, stroke
(North Carolina State University) Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a new ultrasound device that could help identify arterial plaque that is at high risk of breaking off and causing heart attack or stroke.
Source: EurekAlert! - Biology - April 24, 2014 Category: Biology Source Type: news
Blocking key enzyme minimizes stroke injury, UT Southwestern research finds
(UT Southwestern Medical Center) A drug that blocks the action of the enzyme Cdk5 could substantially reduce brain damage if administered shortly after a stroke, UT Southwestern Medical Center research suggests.
Source: EurekAlert! - Biology - June 26, 2014 Category: Biology Source Type: news
Continuing the quest for better stroke therapies
(New Jersey Institute of Technology) Helping people recover from the debilitating effects of a stroke is an immensely complex challenge that requires deep knowledge of neurophysiology as well as effective therapy. Advancing such knowledge to improve therapeutic options and outcomes has been the primary focus of research by Sergei Adamovich, associate professor of biomedical engineering, since he joined the NJIT faculty more than a decade ago.
Source: EurekAlert! - Biology - July 29, 2014 Category: Biology Source Type: news
Kessler Foundation researchers find foot drop stimulator beneficial in stroke rehab
(Kessler Foundation) Kessler Foundation scientists have published a study showing that use of a foot drop stimulator during a task-specific movement for 4 weeks can retrain the neuromuscular system. This finding indicates that applying the foot drop stimulator as rehabilitation intervention may facilitate recovery from this common complication of stroke. 'EMG of the tibialis anterior demonstrates a training effect after utilization of a foot drop stimulator,' was published online ahead of print on July 2 by NeuroRehabilitation
Source: EurekAlert! - Biology - September 23, 2014 Category: Biology Source Type: news
Sweet nanoparticles target stroke
(FECYT - Spanish Foundation for Science and Technology) Materials resulting from chemical bonding of glucosamine, a type of sugar, with fullerenes, kind of nanoparticles known as buckyballs, might help to reduce cell damage and inflammation occurring after stroke. A team from the Max Planck Institute in Germany has tested this on mice, opening the door to potential new drugs for the cerebrovascular accident.
Source: EurekAlert! - Biology - March 12, 2015 Category: Biology Source Type: news
A selective cannabinoid CB2 agonist attenuates damage and improves memory retention following stroke in mice
Publication date: Available online 30 May 2015 Source:Life Sciences Author(s): Richard D. Ronca , Alyssa M. Myers , Doina Ganea , Ronald F. Tuma , Ellen A. Walker , Sara Jane Ward Aims We have recently demonstrated that treatment with a cannabinoid CB2 agonist was protective in a mouse middle cerebral artery occlusion model of cerebral ischemia/reperfusion injury. The present study aimed to determine whether these protective effects of CB2 agonism would extend to a mouse photoinjury model of permanent ischemia and determine associated alterations in cognition and infarct size. Main Methods Mice received three injections...
Source: Life Sciences - May 31, 2015 Category: Biology Source Type: research
Effect of Sodium Nitrite and L-NNA on the Outcome of Experimental Ischemic Stroke
We studied the effect of sodium nitrite in doses of 5 and 50 mg/kg and NO synthase inhibitor L-NNA in a dose of 20 mg/kg on the course of experimental ischemic stroke caused by occlusion of both carotid arteries. Sodium nitrite and NO synthase inhibitor were administered 1 h prior to occlusion of еру carotid arteries and 5 sec after brain ischemia. Sodium nitrite in a dose of 5 mg/kg had a protective effect on the time course of neurological disorders and reduced animal mortality. NO synthase inhibitor L-NNA aggravated the neurological symptoms.
Source: Bulletin of Experimental Biology and Medicine - June 19, 2015 Category: Biology Source Type: research
