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Total 550 results found since Jan 2013.

Effects of remote ischemic conditioning on sleep complaints in Parkinson's disease –rationale, design, and protocol for a randomized controlled study
ConclusionThis study is a prospective randomized controlled trial to determine the safety, feasibility, and potential efficacy of RIC for patients with Parkinson's disease associated with EDS.
Source: Frontiers in Neurology - July 25, 2022 Category: Neurology Source Type: research

Sleep disordered breathing has minimal association with retinal microvascular diameters in a non-diabetic sleep clinic cohort
ConclusionNo major SDB associations with CRAE or CRVE were identified, although the RFM/CPAP intervention reduced evening CRVE for severe OSA patients. Implications for cerebro-vascular disease risk remain uncertain. Trial registrationThe protocol was registered with the Australian New Zealand Clinical Trials Registry (Trial Id: ACTRN12620000694910).
Source: PLoS One - January 10, 2023 Category: Biomedical Science Authors: Kristina Kairaitis Source Type: research

Brain and Cognition Signature Fingerprinting Vascular Health in Diabetic Individuals: An International Multi-Cohort Study
CONCLUSION: Cognitive decline significantly elevates the risk of diabetic vascular complications and is correlated with retinal and renal microcirculation damage. Cognitive screening tests are strongly recommended as routine tools for management of diabetes.PMID:37230837 | DOI:10.1016/j.jagp.2023.04.010
Source: The American Journal of Geriatric Psychiatry - May 25, 2023 Category: Psychiatry Authors: Pingting Zhong Shaoying Tan Zhuoting Zhu Junyao Zhang Shida Chen Wenyong Huang Mingguang He Wei Wang Source Type: research

Applying neurointerventional expertise to save vision from eye strokes
Recent years have seen a dramatic change in the landscape of neurointerventional surgery, in large part due to the significant progress in the treatment of acute ischemic stroke (AIS). This progress has resulted in many thousands of lives saved and the prevention of life-changing morbidity and dependence in many more patients. Although the development of novel endovascular devices and procedural techniques was critical and arguably the ignition for these advances, as we move forward it is the integration of our systems of care and further collaboration with all stakeholders both within and away from the coal face clinical ...
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: De Leacy, R., Lema, G. M. C. Tags: Editor ' s column Source Type: research

Transneuronal Retrograde Degeneration of the Retinal Ganglion Cells in Patients with Cerebral Infarction
Conclusions: Retinal nerve fiber layer thickness was reduced in patients with cerebral infarction, providing evidence for TRD of the RGCs. Transneuronal retrograde degeneration was more pronounced in the nasal nerve fiber layer of the contralateral side and in the temporal nerve fiber layer of the ipsilateral side of cerebral damage. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Source: Ophthalmology - February 11, 2013 Category: Opthalmology Authors: Hae-Young Lopilly Park, Young Gun Park, A-Hyun Cho, Chan Kee Park Tags: Original Articles Source Type: research

Using omega 3 fatty acids to treat Alzheimer's & other diseases?
(Louisiana State University Health Sciences Center) Understanding how dietary essential fatty acids work may lead to effective treatments for diseases and conditions such as stroke, Alzheimer's disease, age-related macular degeneration, Parkinson's disease and other retinal and neurodegenerative diseases. The key is to be able to intervene during the early stages of the disease.
Source: EurekAlert! - Medicine and Health - July 18, 2017 Category: International Medicine & Public Health Source Type: news

Assessment of stability of CD34+ cell products enriched by immunoselection from peripheral blood mononuclear cells during refrigerated storage
Haematopoietic stem cell transplantation is generally used for haematopoietic regeneration after myeloablative therapy [1]. Therapeutic effects of stem cells in other diseases like heart failure [2,3], bone healing [4], chronic spinal cord injuries [5], retinal disorders [6], stroke [7], refractory Crohn disease [8] and multiple sclerosis [9] are being investigated in various clinical studies. Haematopoietic stem cells are most often collected in a mononuclear cell fraction by leukapheresis from peripheral blood.
Source: Transfusion and Apheresis Science - July 21, 2017 Category: Hematology Authors: Metka Krasna, Elvira Malicev, Jasmina Ziva Rozman, Bojan Vrtovec Source Type: research

Letter by Kawada Regarding Article, “Silent Brain Infarctions and Leukoaraiosis in Patients With Retinal Ischemia: A Prospective Single-Center Observational Study” Letter to the Editor
Source: Stroke - July 24, 2017 Category: Neurology Authors: Tomoyuki Kawada Tags: Epidemiology, Risk Factors Letters to the Editor Source Type: research

Prothrombotic Fibrin Clot Phenotype in Patients with Deep Vein Thrombosis and Pulmonary Embolism: A New Risk Factor for Recurrence.
Abstract Prothrombotic fibrin clot phenotype, involving faster formation of dense meshwork composed of thinner and highly branched fibers that are relatively resistant to plasmin-induced lysis, has been reported in patients with not only myocardial infarction or stroke, but also venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT), and/or pulmonary embolism (PE). Prothrombotic fibrin clot phenotype, in particular prolonged clot lysis time, is considered a novel risk factor for VTE as well as venous thrombosis at unusual location, for example, cerebral sinus venous thrombosis, retinal vein obstruct...
Source: Biomed Res - July 27, 2017 Category: Research Authors: Undas A Tags: Biomed Res Int Source Type: research

The association between bouted and non-bouted physical activity on retinopathy prevalence.
CONCLUSION: In this nationally representative sample of adults, those who engaged in non-bouted physical activity had reduced odds of a diagnosis of moderate-to-severe retinopathy. PMID: 28818533 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - August 14, 2017 Category: Internal Medicine Authors: Frith E, Loprinzi PD Tags: Eur J Intern Med Source Type: research

Nutrient intake and urinary incontinence in Korean women: A propensity score ‐matched analysis from the Korea National Health and Nutrition Examination Survey data
ConclusionHigh carbohydrate intake seems to be significantly related to female urinary incontinence in the Korean population.
Source: International Journal of Urology - August 28, 2017 Category: Urology & Nephrology Authors: Jun Ho Lee, Hyo Serk Lee Tags: Original Article Source Type: research

Clinical Presentation of Multiple Cerebral Emboli and Central Retinal Artery Occlusion (CRAO) as signs of Cardiac Myxoma
We present a patient whose history of cerebral emboli and central retinal artery occlusion (CRAO) led to a diagnosis of cardiac myxoma. Neuroimaging studies showed multiple infarcts in the region of the left middle and anterior cerebral arteries. Ophthalmic examination showed gross retinal pallor compatible with left central retinal artery occlusion (CRAO). The etiology of stroke was investigated by performing trans-thoracic echocardiography, which showed a mass in the left atrium compatible with cardiac myxoma. Complete removal of the cardiac tumor was performed by open-heart surgery. Fortunately, after a period of rehabi...
Source: Saudi Journal of Ophthalmology - September 15, 2017 Category: Opthalmology Source Type: research